Effects of alpha-lipoic acid on spatial learning and memory, oxidative stress, and central cholinergic system in a rat model of vascular dementia

Neuroscience Letters

Volumn 587, Issue , 2015, Pages 113-119

  Zhao, Ran ran ^a,b   Xu, Fei ^a   Xu, Xiao chen ^a   Tan, Guo jun ^b   Liu, Liang min ^c   Wu, Ning ^d   Zhang, Wen zhong ^a   Liu, Ji xiang ^a  

^a First Hospital of Handan   (China)

^b HEBEI MEDICAL UNIVERSITY   (China)

^c Department of Neurology The Traditional Chinese Medicine Hospital of Anyang   (China)

^d Department of Cardiology The People's Hospital of Guangxi Zhuang Automous Region   (China)

Author keywords

Acetylcholine; Bilateral common carotid artery occlusion; Chronic cerebral hypoperfusion; Morris water maze; Oxidative stress

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; CHOLINE ACETYLTRANSFERASE; GLUTATHIONE; MALONALDEHYDE; THIOCTIC ACID;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BEHAVIOR ASSESSMENT; BRAIN PERFUSION; CAROTID ARTERY OBSTRUCTION; CHOLINERGIC SYSTEM; COMMON CAROTID ARTERY; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; HIPPOCAMPUS; LIPID PEROXIDATION; MALE; MEMORY ASSESSMENT; MULTIINFARCT DEMENTIA; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; RAT; SPATIAL LEARNING; SPATIAL MEMORY; TISSUE HOMOGENATE; TREATMENT DURATION; ANIMAL; COMPLICATION; DEMENTIA, VASCULAR; DRUG EFFECTS; MEMORY; METABOLISM; PSYCHOLOGY; WISTAR RAT;

ACETYLCHOLINE; ACETYLCHOLINESTERASE; ANIMALS; CAROTID STENOSIS; CHOLINE O-ACETYLTRANSFERASE; DEMENTIA, VASCULAR; HIPPOCAMPUS; MALE; MEMORY; OXIDATIVE STRESS; RATS, WISTAR; SPATIAL LEARNING; THIOCTIC ACID;

EID: 84919935411     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2014.12.037     Document Type: Article

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