-
2
-
-
84904754826
-
Current management of esophageal cancer
-
PID: 2486844
-
D’Journo XB, Thomas PA. Current management of esophageal cancer. J Thorac Dis. 2014;6(Suppl 2):S253–64.
-
(2014)
J Thorac Dis
, vol.6
, pp. S253-S264
-
-
D’Journo, X.B.1
Thomas, P.A.2
-
4
-
-
84890569411
-
Molecular alterations and clinical relevance in esophageal squamous cell carcinoma
-
PID: 2400274
-
Shang L, Wang M. Molecular alterations and clinical relevance in esophageal squamous cell carcinoma. Front Med. 2013;7:401–10.
-
(2013)
Front Med
, vol.7
, pp. 401-410
-
-
Shang, L.1
Wang, M.2
-
5
-
-
2442585463
-
Molecular aspects of esophageal squamous cell carcinoma carcinogenesis
-
PID: 1526404
-
Lehrbach DM, Nita ME, Cecconello I. Molecular aspects of esophageal squamous cell carcinoma carcinogenesis. Arq Gastroenterol. 2003;40:256–61.
-
(2003)
Arq Gastroenterol
, vol.40
, pp. 256-261
-
-
Lehrbach, D.M.1
Nita, M.E.2
Cecconello, I.3
-
6
-
-
84907195505
-
Acute regulation of PDK1 by a complex interplay of molecular switches
-
COI: 1:CAS:528:DC%2BC2cXhsFGhsbbE, PID: 2523342
-
Calleja V, Laguerre M, de Las Heras-Martinez G, Parker PJ, Requejo-Isidro J, Larijani B. Acute regulation of PDK1 by a complex interplay of molecular switches. Biochem Soc Trans. 2014;42:1435–40.
-
(2014)
Biochem Soc Trans
, vol.42
, pp. 1435-1440
-
-
Calleja, V.1
Laguerre, M.2
de Las Heras-Martinez, G.3
Parker, P.J.4
Requejo-Isidro, J.5
Larijani, B.6
-
7
-
-
84914168775
-
Expression of Akt kinase-interacting protein 1, a scaffold protein of the PI3 K/PDK1/Akt pathway, in pancreatic cancer
-
COI: 1:CAS:528:DC%2BC2cXhsFKns7rL, PID: 2503690
-
Ohtsubo K, Yamada T, Zhao L, Jin TF, Takeuchi S, Mouri H, Yamashita K, Yasumoto K, Fujita N, Kitagawa H, Ohta T, Ikeda H, Yano S. Expression of Akt kinase-interacting protein 1, a scaffold protein of the PI3 K/PDK1/Akt pathway, in pancreatic cancer. Pancreas. 2014;43:1093–100.
-
(2014)
Pancreas
, vol.43
, pp. 1093-1100
-
-
Ohtsubo, K.1
Yamada, T.2
Zhao, L.3
Jin, T.F.4
Takeuchi, S.5
Mouri, H.6
Yamashita, K.7
Yasumoto, K.8
Fujita, N.9
Kitagawa, H.10
Ohta, T.11
Ikeda, H.12
Yano, S.13
-
8
-
-
84899510151
-
MicroRNA-375 targets PDK1 in pancreatic carcinoma and suppresses cell growth through the Akt signaling pathway
-
COI: 1:CAS:528:DC%2BC2cXptFynsLw%3D, PID: 2448126
-
Zhou J, Song S, He S, Zhu X, Zhang Y, Yi B, Zhang B, Qin G, Li D. MicroRNA-375 targets PDK1 in pancreatic carcinoma and suppresses cell growth through the Akt signaling pathway. Int J Mol Med. 2014;33:950–6.
-
(2014)
Int J Mol Med
, vol.33
, pp. 950-956
-
-
Zhou, J.1
Song, S.2
He, S.3
Zhu, X.4
Zhang, Y.5
Yi, B.6
Zhang, B.7
Qin, G.8
Li, D.9
-
9
-
-
84877840852
-
Upregulation of PKCη by PKCε and PDK1 involves two distinct mechanisms and promotes breast cancer cell survival
-
COI: 1:CAS:528:DC%2BC3sXptV2mtr4%3D, PID: 2356276
-
Pal D, Outram SP, Basu A. Upregulation of PKCη by PKCε and PDK1 involves two distinct mechanisms and promotes breast cancer cell survival. Biochim Biophys Acta. 2013;1830:4040–5.
-
(2013)
Biochim Biophys Acta
, vol.1830
, pp. 4040-4045
-
-
Pal, D.1
Outram, S.P.2
Basu, A.3
-
10
-
-
84904527473
-
Prognostic potential of microRNA-138 and its target mRNA PDK1 in sera for patients with non-small cell lung cancer
-
PID: 2506473
-
Han L, Zhang G, Zhang N, Li H, Liu Y, Fu A, Zheng Y. Prognostic potential of microRNA-138 and its target mRNA PDK1 in sera for patients with non-small cell lung cancer. Med Oncol. 2014;31:129.
-
(2014)
Med Oncol
, vol.31
, pp. 129
-
-
Han, L.1
Zhang, G.2
Zhang, N.3
Li, H.4
Liu, Y.5
Fu, A.6
Zheng, Y.7
-
11
-
-
84873623573
-
Silencing of PDK1 gene expression by RNA interference suppresses growth of esophageal cancer
-
PID: 2309853
-
Yu J, Chen KS, Li YN, Yang J, Zhao L. Silencing of PDK1 gene expression by RNA interference suppresses growth of esophageal cancer. Asian Pac J Cancer Prev. 2012;13:4147–51.
-
(2012)
Asian Pac J Cancer Prev
, vol.13
, pp. 4147-4151
-
-
Yu, J.1
Chen, K.S.2
Li, Y.N.3
Yang, J.4
Zhao, L.5
-
12
-
-
84922670463
-
-
Chen MQ, Xu BH, Zhang YY. Analysis of prognostic factors for esophageal squamous cell carcinoma with distant organ metastasis at initial diagnosis. J Chin Med Assoc. 2014 (in press)
-
Chen MQ, Xu BH, Zhang YY. Analysis of prognostic factors for esophageal squamous cell carcinoma with distant organ metastasis at initial diagnosis. J Chin Med Assoc. 2014 (in press).
-
-
-
-
13
-
-
84872321691
-
Cellular regulation by protein phosphorylation
-
COI: 1:CAS:528:DC%2BC3sXnvVWi, PID: 2305892
-
Fischer EH. Cellular regulation by protein phosphorylation. Biochem Biophys Res Commun. 2013;430:865–7.
-
(2013)
Biochem Biophys Res Commun
, vol.430
, pp. 865-867
-
-
Fischer, E.H.1
-
14
-
-
84869007032
-
Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors
-
COI: 1:CAS:528:DC%2BC38Xhs1enurjP, PID: 2303082
-
Najafov A, Shpiro N, Alessi DR. Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors. Biochem J. 2012;448:285–95.
-
(2012)
Biochem J
, vol.448
, pp. 285-295
-
-
Najafov, A.1
Shpiro, N.2
Alessi, D.R.3
-
15
-
-
84865214853
-
A novel regulatory mechanism links PLCγ1 to PDK1
-
COI: 1:CAS:528:DC%2BC38XhsVKiurbO, PID: 2245452
-
Raimondi C, Chikh A, Wheeler AP, Maffucci T, Falasca M. A novel regulatory mechanism links PLCγ1 to PDK1. J Cell Sci. 2012;125:3153–63.
-
(2012)
J Cell Sci
, vol.125
, pp. 3153-3163
-
-
Raimondi, C.1
Chikh, A.2
Wheeler, A.P.3
Maffucci, T.4
Falasca, M.5
-
16
-
-
79959365543
-
Targeting PDK1 in cancer
-
COI: 1:CAS:528:DC%2BC3MXht1Cit73I, PID: 2156890
-
Raimondi C, Falasca M. Targeting PDK1 in cancer. Curr Med Chem. 2011;18:2763–9.
-
(2011)
Curr Med Chem
, vol.18
, pp. 2763-2769
-
-
Raimondi, C.1
Falasca, M.2
-
17
-
-
27144480288
-
Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(±) mice
-
COI: 1:CAS:528:DC%2BD2MXhtFCjsL%2FO, PID: 1624303
-
Bayascas JR, Leslie NR, Parsons R, Fleming S, Alessi DR. Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(±) mice. Curr Biol. 2005;15:1839–46.
-
(2005)
Curr Biol
, vol.15
, pp. 1839-1846
-
-
Bayascas, J.R.1
Leslie, N.R.2
Parsons, R.3
Fleming, S.4
Alessi, D.R.5
-
18
-
-
84899745758
-
The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts
-
COI: 1:CAS:528:DC%2BC2cXhvVCru7vO, PID: 2433429
-
Zabkiewicz J, Pearn L, Hills RK, Morgan RG, Tonks A, Burnett AK, Darley RL. The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts. Haematologica. 2014;99:858–64.
-
(2014)
Haematologica
, vol.99
, pp. 858-864
-
-
Zabkiewicz, J.1
Pearn, L.2
Hills, R.K.3
Morgan, R.G.4
Tonks, A.5
Burnett, A.K.6
Darley, R.L.7
-
19
-
-
0037096904
-
Transformation of mammary epithelial cells by 3-phosphoinositide-dependent protein kinase-1 (PDK1) is associated with the induction of protein kinase Calpha
-
COI: 1:CAS:528:DC%2BD38XkslWqt74%3D, PID: 1206800
-
Zeng X, Xu H, Glazer RI. Transformation of mammary epithelial cells by 3-phosphoinositide-dependent protein kinase-1 (PDK1) is associated with the induction of protein kinase Calpha. Cancer Res. 2002;62:3538–43.
-
(2002)
Cancer Res
, vol.62
, pp. 3538-3543
-
-
Zeng, X.1
Xu, H.2
Glazer, R.I.3
-
20
-
-
84872548105
-
PDK1 inhibition is a novel therapeutic target in multiple myeloma
-
COI: 1:CAS:528:DC%2BC3sXhtFCmtro%3D, PID: 2332151
-
Fujiwara S, Kawano Y, Yuki H, Okuno Y, Nosaka K, Mitsuya H, Hata H. PDK1 inhibition is a novel therapeutic target in multiple myeloma. Br J Cancer. 2013;108:170–8.
-
(2013)
Br J Cancer
, vol.108
, pp. 170-178
-
-
Fujiwara, S.1
Kawano, Y.2
Yuki, H.3
Okuno, Y.4
Nosaka, K.5
Mitsuya, H.6
Hata, H.7
-
21
-
-
84862544843
-
Antitumor mechanisms of targeting the PDK1 pathway in head and neck cancer
-
COI: 1:CAS:528:DC%2BC38XotlCis7c%3D, PID: 2249180
-
Bhola NE, Freilino ML, Joyce SC, Sen M, Thomas SM, Sahu A, Cassell A, Chen CS, Grandis JR. Antitumor mechanisms of targeting the PDK1 pathway in head and neck cancer. Mol Cancer Ther. 2012;11:1236–46.
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 1236-1246
-
-
Bhola, N.E.1
Freilino, M.L.2
Joyce, S.C.3
Sen, M.4
Thomas, S.M.5
Sahu, A.6
Cassell, A.7
Chen, C.S.8
Grandis, J.R.9
-
22
-
-
84909582372
-
Emerging role of the KRAS-PDK1 axis in pancreatic cancer
-
COI: 1:CAS:528:DC%2BC2cXhvFajurbL, PID: 2515257
-
Ferro R, Falasca M. Emerging role of the KRAS-PDK1 axis in pancreatic cancer. World J Gastroenterol. 2014;20:10752–7.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 10752-10757
-
-
Ferro, R.1
Falasca, M.2
-
23
-
-
78650417431
-
Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer
-
COI: 1:CAS:528:DC%2BC3cXhs1Wktb3I, PID: 2103546
-
Slattery ML, Lundgreen A, Herrick JS, Wolff RK. Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer. Mutat Res. 2011;706:13–20.
-
(2011)
Mutat Res
, vol.706
, pp. 13-20
-
-
Slattery, M.L.1
Lundgreen, A.2
Herrick, J.S.3
Wolff, R.K.4
-
24
-
-
84899909540
-
Immunohistochemical analysis of PDK1 expression in breast cancer
-
PID: 2473948
-
Arsenic R. Immunohistochemical analysis of PDK1 expression in breast cancer. Diagn Pathol. 2014;9:82.
-
(2014)
Diagn Pathol.
, vol.9
, pp. 82
-
-
Arsenic, R.1
|