-
1
-
-
17244377075
-
Direct comparison of the specificity of gene silencing using antisense oligonucleotides and RNAi
-
Bilanges B, Stokoe D (2005). Direct comparison of the specificity of gene silencing using antisense oligonucleotides and RNAi. Biochemcal J, 388, 573-8
-
(2005)
Biochemcal J
, vol.388
, pp. 573-578
-
-
Bilanges, B.1
Stokoe, D.2
-
2
-
-
77949452524
-
The PKB/AKT pathway in cancer
-
Carnero A (2010). The PKB/AKT pathway in cancer. Curr Pharm Des, 16, 34-4
-
(2010)
Curr Pharm Des
, vol.16
, pp. 34-44
-
-
Carnero, A.1
-
3
-
-
20044375047
-
Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1, and AKT and the effect of therapeutic kinase inhibitors on cell survival
-
Carón RW, Yacoub A, Li M, et a1 (2005). Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1, and AKT and the effect of therapeutic kinase inhibitors on cell survival. Mol Cancer Ther, 4, 257-7
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 257-267
-
-
Carón, R.W.1
Yacoub, A.2
Li, M.3
-
4
-
-
0032545933
-
Potent and specific interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, et a1 (1998). Potent and specific interference by double-stranded RNA in Caenorhabditis elegans. Nature, 391, 806-1
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
-
5
-
-
32944465388
-
Handicapping the race to develop inhibitors of the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway
-
Granville CA, Memmott RM, Gills JJ, Dennis PA (2006). Handicapping the race to develop inhibitors of the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway. Clin Cancer Res, 12, 679-8
-
(2006)
Clin Cancer Res
, vol.12
, pp. 679-688
-
-
Granville, C.A.1
Memmott, R.M.2
Gills, J.J.3
Dennis, P.A.4
-
6
-
-
60849109531
-
Genetic variations in the PI3K/PTEN /AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy
-
Hildebrandt MA, Yang H, Hung MC, et a1 (2009). Genetic variations in the PI3K/PTEN /AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy. J Clin Oncol, 27, 857-7
-
(2009)
J Clin Oncol
, vol.27
, pp. 857-867
-
-
Hildebrandt, M.A.1
Yang, H.2
Hung, M.C.3
-
7
-
-
2342564353
-
A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens
-
Hsieh AC, Bo R, Manola J, et a1 (2004). A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens. Nucleic Acids Research, 32, 893-90
-
(2004)
Nucleic Acids Research
, vol.32
, pp. 893-990
-
-
Hsieh, A.C.1
Bo, R.2
Manola, J.3
-
8
-
-
58249090328
-
Parallel RNAi and compound screens identify the PDK1 pathway as a target for tamoxifen sensitisation
-
Iorns E, Lord CJ, Ashworth A (2009). Parallel RNAi and compound screens identify the PDK1 pathway as a target for tamoxifen sensitisation. Biochem J, 417, 361-7
-
(2009)
Biochem J
, vol.417
, pp. 361-367
-
-
Iorns, E.1
Lord, C.J.2
Ashworth, A.3
-
9
-
-
70349098422
-
Resveratrol downregulates PI3K/Akt/mTOR signaling pathways in human U251 glioma cells
-
Jiang H, Shang X, Wu H, et al (2009). Resveratrol downregulates PI3K/Akt/mTOR signaling pathways in human U251 glioma cells. J Exp Ther Oncol, 8, 25-3
-
(2009)
J Exp Ther Oncol
, vol.8
, pp. 25-33
-
-
Jiang, H.1
Shang, X.2
Wu, H.3
-
10
-
-
76649128715
-
Phosphatidylinositol 3-kinase (PI3K) pathway activation in bladder cancer
-
Knowles MA, Platt FM, Ross RL, Hurst CD (2009). Phosphatidylinositol 3-kinase (PI3K) pathway activation in bladder cancer. Cancer Metastasis Rev, 28, 305-1
-
(2009)
Cancer Metastasis Rev
, vol.28
, pp. 305-311
-
-
Knowles, M.A.1
Platt, F.M.2
Ross, R.L.3
Hurst, C.D.4
-
11
-
-
36148964068
-
Id-1 activation of PI3K/Akt/NFkB signaling pathway and its significance in promoting survival of esophageal cancer cells
-
Li B, Cheung PY, Wang X, Tsao SW, et al (2007). Id-1 activation of PI3K/Akt/NFkB signaling pathway and its significance in promoting survival of esophageal cancer cells. Carcinogenesis, 28, 2313-2
-
(2007)
Carcinogenesis
, vol.28
, pp. 2313-2322
-
-
Li, B.1
Cheung, P.Y.2
Wang, X.3
Tsao, S.W.4
-
12
-
-
33747610198
-
Differential roles of phosphoinositide-dependent protein kinase-1 and akt1 expression and phosphorylation in breast cancer cell resistance to Paclitaxel, Doxorubicin, and gemcitabine
-
Liang K, Lu Y, Li X, et al (2006). Differential roles of phosphoinositide-dependent protein kinase-1 and akt1 expression and phosphorylation in breast cancer cell resistance to Paclitaxel, Doxorubicin, and gemcitabine. Mol Pharmacol, 70, 1045-5
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1045-1055
-
-
Liang, K.1
Lu, Y.2
Li, X.3
-
13
-
-
67649604297
-
Down-regulation of 3-phosphoinositide-dependent protein kinase-1 levels inhibits migration and experimental metastasis of human breast cancer cells
-
Liu Y, Wang J, Wu M, et al (2009). Down-regulation of 3-phosphoinositide-dependent protein kinase-1 levels inhibits migration and experimental metastasis of human breast cancer cells. Mol Cancer Res, 7, 944-5
-
(2009)
Mol Cancer Res
, vol.7
, pp. 944-945
-
-
Liu, Y.1
Wang, J.2
Wu, M.3
-
14
-
-
77957819681
-
The phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients
-
Martelli AM, Evangelisti C, Chiarini F, McCubrey JA (2010). The phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients. Oncotarget, 1, 89-10
-
(2010)
Oncotarget
, vol.1
, pp. 89-10
-
-
Martelli, A.M.1
Evangelisti, C.2
Chiarini, F.3
McCubrey, J.A.4
-
15
-
-
70350560575
-
Current perspectives on Akt Akt-ivation and Akt-ions
-
Matheny RW Jr, Adamo ML (2009). Current perspectives on Akt Akt-ivation and Akt-ions. Exp Biol Med, 234, 1264-7
-
(2009)
Exp Biol Med
, vol.234
, pp. 1264-1267
-
-
Matheny Jr., R.W.1
Adamo, M.L.2
-
17
-
-
58249092754
-
New anti-cancer role for PDK1 inhibitors: preventing resistance to tamoxifen
-
Peifer C, Alessi DR (2009). New anti-cancer role for PDK1 inhibitors: preventing resistance to tamoxifen. Biochem J, 417, e5-7
-
(2009)
Biochem J
, vol.417
-
-
Peifer, C.1
Alessi, D.R.2
-
18
-
-
45049087900
-
Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells
-
Tamgüney T, Zhang C, Fiedler D, Shokat K, Stokoe D (2008). Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells. Exp Cell Res, 314, 2299-31
-
(2008)
Exp Cell Res
, vol.314
, pp. 2299-2231
-
-
Tamgüney, T.1
Zhang, C.2
Fiedler, D.3
Shokat, K.4
Stokoe, D.5
-
19
-
-
74249086913
-
Activation of PI3KAKT pathway in oral epithelial dysplasia and early cancer of tongue
-
Watanabe S, Sato K, Okazaki Y, et al (2009). Activation of PI3KAKT pathway in oral epithelial dysplasia and early cancer of tongue. Bull Tokyo Dent Coll, 50, 125-3
-
(2009)
Bull Tokyo Dent Coll
, vol.50
, pp. 125-123
-
-
Watanabe, S.1
Sato, K.2
Okazaki, Y.3
-
20
-
-
23944506289
-
RNA interference is an antiviral defence mechanism in Caenorhabditis elegans
-
Wilkins C, Dishongh R, Moore SC, et al (2005). RNA interference is an antiviral defence mechanism in Caenorhabditis elegans. Nature, 436, 1044-7
-
(2005)
Nature
, vol.436
, pp. 1044-1047
-
-
Wilkins, C.1
Dishongh, R.2
Moore, S.C.3
-
21
-
-
85008408631
-
Small interfering RNA PDK1 inhibits breast cancer cell line invasion and metastasis
-
Wu M, Wu J, Xu Y, et al (2009). Small interfering RNA PDK1 inhibits breast cancer cell line invasion and metastasis, Chinese J Clin Oncol, 36, 697-70
-
(2009)
Chinese J Clin Oncol
, vol.36
, pp. 697-670
-
-
Wu, M.1
Wu, J.2
Xu, Y.3
|