Mitochondrial induced and self-monitored intrinsic apoptosis by antitumor theranostic prodrug: In vivo imaging and precise cancer treatment

Journal of the American Chemical Society

Volumn 136, Issue 51, 2014, Pages 17836-17843

  Kumar, Rajesh ^a   Han, Jiyou ^a   Lim, Hee Joung ^a   Ren, Wen Xiu ^a   Lim, Ja Yun ^a   Kim, Jong Hoon ^a   Kim, Jong Seung ^a  

^a Korea University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; CELL MEMBRANES; CHEMICAL ACTIVATION; DISEASES; DRUG PRODUCTS; GENE EXPRESSION; MACHINERY; MITOCHONDRIA; TUMORS;

APOPTOTIC GENES; APOPTOTIC MARKERS; CANCER THERAPY; EARLY DIAGNOSIS; IN-VIVO IMAGING; SELF-MONITORING; THERANOSTIC AGENTS; TUMOR PROGRESSIONS;

DIAGNOSIS;

5' DEOXY 5 FLUOROCYTIDINE; CASPASE 3; CASPASE 9; CELL SURFACE RECEPTOR; CYTOCHROME C; DEATH RECEPTOR; ETHIDIUM; HYDROGEN PEROXIDE; PROTEIN BAK; PROTEIN BAX; PROTEIN BID; PROTEIN NOXA; PUMA PROTEIN; ANTINEOPLASTIC AGENT; DOXIFLURIDINE; FLOXURIDINE; PRODRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER THERAPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG RELEASE; EX VIVO STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG CANCER; MITOCHONDRION; MOUSE; NONHUMAN; TUMOR GROWTH; ANIMAL; CHEMISTRY; DRUG EFFECTS; FLUORESCENCE IMAGING; LUNG NEOPLASMS; MOLECULARLY TARGETED THERAPY; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; FLOXURIDINE; HUMANS; LUNG NEOPLASMS; MICE; MITOCHONDRIA; MOLECULAR TARGETED THERAPY; OPTICAL IMAGING; PRODRUGS;

EID: 84919905487     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja510421q     Document Type: Article

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