Increasing magnetite contents of polymeric magnetic particles dramatically improves labeling of neural stem cell transplant populations

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 11, Issue 1, 2015, Pages 19-29

  Adams, Christopher F ^a   Rai, Ahmad ^b   Sneddon, Gregor ^c   Yiu, Humphrey H P ^c   Polyak, Boris ^b   Chari, Divya M ^a  

^a KEELE UNIVERSITY   (United Kingdom)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c HERIOT WATT UNIVERSITY   (United Kingdom)

Author keywords

Labeling; Magnetic cell targeting; Neural stem cells; Polymeric magnetic particles; Transplant cells

Indexed keywords

CYTOLOGY; LABELING; MAGNETIC BUBBLES; MAGNETISM; MAGNETITE; NEUROPHYSIOLOGY; POLYMERS;

CELL TRANSPLANTATION; CENTRAL NERVOUS SYSTEMS; MAGNETIC CELLS; MAGNETIC LOCALIZATION; MAGNETIC PARTICLE; MAGNETITE CONTENTS; NEURAL STEM CELL; TARGETED DELIVERY;

STEM CELLS;

GLIAL FIBRILLARY ACIDIC PROTEIN; MAGNETITE; NESTIN; POLYLACTIC ACID; BIOMATERIAL; LACTIC ACID; MAGNETITE NANOPARTICLE; POLYMER;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LABELING; CELL POPULATION; CELL REGENERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; IN VITRO STUDY; MAGNETIC FIELD; NEURAL STEM CELL TRANSPLANTATION; NONHUMAN; PARTICLE SIZE; POLYMERIZATION; SUBVENTRICULAR ZONE; ANIMAL; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; HUMAN; MAGNETISM; METABOLISM; NANOMEDICINE; NERVE CELL; NEURAL STEM CELL; PROCEDURES; REGENERATION; STEM CELL TRANSPLANTATION;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELL DIFFERENTIATION; CELL PROLIFERATION; HUMANS; LACTIC ACID; MAGNETICS; MAGNETITE NANOPARTICLES; NANOMEDICINE; NEURAL STEM CELLS; NEURONS; POLYMERS; REGENERATION; STEM CELL TRANSPLANTATION;

EID: 84919844469     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2014.07.001     Document Type: Article

References (50)

1. Aboody K., Capela A., Niazi N., Stern J.H., Temple S. Translating stem cell studies to the clinic for CNS repair: current state of the art and the need for a Rosetta stone. Neuron 2011, 70:597-613.
2. Hauger O., Frost E.E., van Heeswijk R., Deminière C., Xue R., Delmas Y., et al. MR evaluation of the glomerular homing of magnetically labeled mesenchymal stem cells in a rat model of nephropathy. Radiology 2006, 238:200-210.
3. Kraitchman D.L., Tatsumi M., Gilson W.D., Ishimori T., Kedziorek D., Walczak P., et al. Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction. Circulation 2005, 112:1451-1461.
4. Li L., Jiang Q., Ding G., Zhang L., Zhang Z.G., Li Q., et al. Effects of administration route on migration and distribution of neural progenitor cells transplanted into rats with focal cerebral ischemia, an MRI study. J Cereb Blood Flow Metab 2010, 30:653-662.
5. Carenza E., Barceló V., Morancho A., Levander L., Boada C., Laromaine A., et al. In vitro angiogenic performance and in vivo brain targeting of magnetized endothelial progenitor cells for neurorepair therapies. Nanomedicine 2014, 10:225-234.
6. Song M., Kim Y.-J., Kim Y., Roh J., Kim S.U., Yoon B.-W. Using a neodymium magnet to target delivery of ferumoxide-labeled human neural stem cells in a rat model of focal cerebral ischemia. Hum Gene Ther 2010, 21:603-610.
7. Vaněček V., Zablotskii V., Forostyak S., Růřička J., Herynek V., Babič M., et al. Highly efficient magnetic targeting of mesenchymal stem cells in spinal cord injury. Int J Nanomedicine 2012, 7:3719-3730.
8. Polyak B., Fishbein I., Chorny M., Alferiev I., Williams D., Yellen B., et al. High field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stents. Proc Natl Acad Sci U S A 2008, 105:698-703.
9. Cheng K., Li T., Malliaras K. Magnetic targeting enhances engraftment and functional benefit of iron-labeled cardiosphere-derived cells in myocardial infarction. Circulation 2010, 106:1570-1581.
10. Pluchino S., Quattrini A., Brambilla E., Gritti A., Salani G., Dina G., et al. Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis. Nature 2003, 422:688-694.
11. Cohen M.E., Muja N., Fainstein N., Bulte J.W.M., Ben-Hur T. Conserved fate and function of ferumoxides-labeled neural precursor cells in vitro and in vivo. J Neurosci Res 2010, 88:936-944.
12. Bakhru S.H., Altiok E., Highley C., Delubac D., Suhan J., Hitchens T.K., et al. Enhanced cellular uptake and long-term retention of chitosan-modified iron-oxide nanoparticles for MRI-based cell tracking. Int J Nanomedicine 2012, 7:4613-4623.
13. Delehanty J.B., Boeneman K., Bradburne C.E., Robertson K., Bongard J.E., Medintz I.L. Peptides for specific intracellular delivery and targeting of nanoparticles: implications for developing nanoparticle-mediated drug delivery. Ther Deliv 2010, 1:411-433.
14. Arbab A.S., Yocum G.T., Wilson L.B., Parwana A., Jordan E.K., Kalish H., et al. Comparison of transfection agents in forming complexes with ferumoxides, cell labeling efficiency, and cellular viability. Mol Imaging 2004, 3:24-32.
15. Lee S.H., Castagner B., Leroux J.-C. Is there a future for cell-penetrating peptides in oligonucleotide delivery?. Eur J Pharm Biopharm 2013, 85:5-11.
16. Plank C., Zelphati O., Mykhaylyk O. Magnetically enhanced nucleic acid delivery. Adv Drug Deliv Rev 2011, 63:1300-1331.
17. MacDonald C., Barbee K., Polyak B. Force dependent internalization of magnetic nanoparticles results in highly loaded endothelial cells for use as potential therapy delivery vectors. Pharm Res 2012, 29:1270-1281.
18. Soenen S.J., De Smedt S.C., Braeckmans K. Limitations and caveats of magnetic cell labeling using transfection agent complexed iron oxide nanoparticles. Contrast Media Mol Imaging 2012, 7:140-152.
19. Politi L.S., Bacigaluppi M., Brambilla E., Cadioli M., Falini A., Comi G., et al. Magnetic-resonance-based tracking and quantification of intravenously injected neural stem cell accumulation in the brains of mice with experimental multiple sclerosis. Stem Cells 2007, 25:2583-2592.
20. Neri M., Maderna C., Cavazzin C., Deidda-Vigoriti V., Politi L.S., Scotti G., et al. Efficient in vitro labeling of human neural precursor cells with superparamagnetic iron oxide particles: relevance for in vivo cell tracking. Stem Cells 2008, 26:505-516.
21. Chen C.-C.V., Ku M.-C., DMJ, Lai J.-S., Hueng D.-Y., Chang C. Simple SPION incubation as an efficient intracellular labeling method for tracking neural progenitor cells using MRI. PLoS One 2013, 8:e56125.
22. Johnson B., Toland B., Chokshi R., Mochalin V., Koutzaki S., Polyak B. Magnetically responsive paclitaxel-loaded biodegradable nanoparticles for treatment of vascular disease: preparation, characterization and in vitro evaluation of anti-proliferative potential. Curr Drug Deliv 2010, 7:263-273.
23. Pickard M.R., Barraud P., Chari D.M. The transfection of multipotent neural precursor/stem cell transplant populations with magnetic nanoparticles. Biomaterials 2011, 32:2274-2284.
24. Jenkins S., Pickard M., Furness D., Yiu H., Chari D. Differences in magnetic particle uptake by CNS neuroglial subclasses: implications for neural tissue engineering. Nanomedicine (Lond) 2013, 8:951-968.
25. Pickard M., Jenkins S., Koller C., Furness D., Chari D. Magnetic nanoparticle labeling of astrocytes derived for neural transplantation. Tissue Eng Part C Methods 2010, 17:89-99.
26. Luther E.M., Petters C., Bulcke F., Kaltz A., Thiel K., Bickmeyer U., et al. Endocytotic uptake of iron oxide nanoparticles by cultured brain microglial cells. Acta Biomater 2013, 9:8454-8465.
27. Marieb E.N. The cardiovascular system: blood vessels. Hum Anat Physiol Int Ed 2004, 721-739. Pearson Education, San Francisco. M.A. Murray (Ed.).
28. Albanese A., Tang P.S., Chan W.C.W. The effect of nanoparticle size, shape, and surface chemistry on biological systems. Ann Rev Biomed Eng 2012, 14:1-16.
29. Fröhlich E. The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles. Int J Nanomedicine 2012, 7:5577-5591.
30. Labille J., Brant J. Stability of nanoparticles in water. Nanomedicine (Lond) 2010, 5:985-998.
31. Zhao F., Zhao Y., Liu Y., Chang X., Chen C., Zhao Y. Cellular uptake, intracellular trafficking, and cytotoxicity of nanomaterials. Small 2011, 7:1322-1337.
32. Gref R., Miralles G., Dellacherie É. Polyoxyethylene-coated nanospheres: effect of coating on zeta potential and phagocytosis. Polym Int 1999, 48:251-256.
33. Sahoo S.K., Panyam J., Prabha S., Labhasetwar V. Residual polyvinyl alcohol associated with poly (d, l-lactide-co-glycolide) nanoparticles affects their physical properties and cellular uptake. J Control Release 2002, 82:105-114.
34. Chorny M., Polyak B., Alferiev I.S., Walsh K., Friedman G., Levy R.J. Magnetically driven plasmid DNA delivery with biodegradable polymeric nanoparticles. FASEB J 2007, 21:2510-2519.
35. Jenkins S.I., Pickard M.R., Granger N., Chari D.M. Magnetic nanoparticle-mediated gene transfer to oligodendrocyte precursor cell transplant populations is enhanced by magnetofection strategies. ACS Nano 2011, 5:6527-6538.
36. Pickard M., Chari D. Enhancement of magnetic nanoparticle-mediated gene transfer to astrocytes by "magnetofection": effects of static and oscillating fields. Nanomedicine (Lond) 2010, 5:217-232.
37. Arsianti M., Lim M., Marquis C.P., Amal R. Assembly of polyethylenimine-based magnetic iron oxide vectors: insights into gene delivery. Langmuir 2010, 26:7314-7326.
38. Ganguly S., Chakraborty S. Sedimentation of nanoparticles in nanoscale colloidal suspensions. Phys Lett A 2011, 375:2394-2399.
39. Sahni V., Kessler J.A. Stem cell therapies for spinal cord injury. Nat Rev Neurol 2010, 6:363-372.
40. Gupta B., Revagade N., Hilborn J. Poly(lactic acid) fiber: an overview. Prog Polym Sci 2007, 32:455-482.
41. Lin Xiao M., Wang B., Yang G., Gauthier M. Poly(lactic acid)-based biomaterials: synthesis, modification and applications. Biomed Sci Eng Technol InTech 2012, 247-282. D. Ghista (Ed.).
42. Grayson A.C.R., Voskerician G., Lynn A., Anderson J.M., Cima M.J., Langer R. Differential degradation rates in vivo and in vitro of biocompatible poly(lactic acid) and poly(glycolic acid) homo- and co-polymers for a polymeric drug-delivery microchip. J Biomater Sci Polym Ed 2004, 15:1281-1304.
43. Tengood J.E., Alferiev I.S., Zhang K., Fishbein I., Levy R.J., Chorny M. Real-time analysis of composite magnetic nanoparticle disassembly in vascular cells and biomimetic media. Proc Natl Acad Sci U S A 2014, 111:4245-4250.
44. Worthington-Kirsch R.L., Siskin G.P., Hegener P., Chesnick R. Comparison of the efficacy of the embolic agents acrylamido polyvinyl alcohol microspheres and tris-acryl gelatin microspheres for uterine artery embolization for leiomyomas: a prospective randomized controlled trial. Cardiovasc Interv Radiol 2011, 34:493-501.
45. Jain T.K., Reddy M.K., Morales M.A., Leslie-Pelecky D.L., Labhasetwar V. Biodistribution, clearance, and biocompatibility of iron oxide magnetic nanoparticles in rats. Mol Pharm 2008, 5:316-327.
46. Weissleder R., Stark D.D., Engelstad B.L., Bacon B.R., Compton C.C., White D.L., et al. Superparamagnetic iron oxide: pharmacokinetics and toxicity. AJR Am J Roentgenol 1989, 152:167-173.
47. Tartaj P. Nanomagnets for biomedical applications. Encycl Nanosci Nanotechnol 2003, vol. 6:823. American Scientific Publishers. N. Hari Singh (Ed.).
48. Santos T., Ferreira R., Maia J., Agasse F., Xapelli S., Cortes L., et al. Polymeric nanoparticles to control the differentiation of neural stem cells in the subventricular zone of the brain. ACS Nano 2012, 6:10463-10474.
49. Miyoshi S., Flexman J.A., Cross D.J., Maravilla K.R., Kim Y., Anzai Y., et al. Transfection of neuroprogenitor cells with iron nanoparticles for magnetic resonance imaging tracking: cell viability, differentiation, and intracellular localization. Mol Imaging Biol 2005, 7:286-295.
50. Shive M., Anderson J. Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv Drug Deliv Rev 1997, 28:5-24.