메뉴 건너뛰기




Volumn 5, Issue 8, 2011, Pages 6527-6538

Magnetic nanoparticle-mediated gene transfer to oligodendrocyte precursor cell transplant populations is enhanced by magnetofection strategies

Author keywords

gene therapy; magnetic nanoparticles; magnetofection; oligodendrocyte precursor cells; organotypic slice culture; transfection; transplantation

Indexed keywords

MAGNETIC NANOPARTICLES; MAGNETOFECTION; OLIGODENDROCYTES; ORGANOTYPIC SLICE CULTURE; TRANSFECTION;

EID: 80052047993     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn2018717     Document Type: Article
Times cited : (89)

References (71)
  • 1
    • 15444373957 scopus 로고    scopus 로고
    • Stem cell therapy for myelin diseases
    • DOI 10.2174/1389450053345000
    • Ben-Hur, T.; Einstein, O.; Bulte, J. W. M. Stem Cell Therapy for Myelin Diseases Curr. Drug Targets 2005, 6, 3-19 (Pubitemid 40394319)
    • (2005) Current Drug Targets , vol.6 , Issue.1 , pp. 3-19
    • Ben-Hur, T.1    Einstein, O.2    Bulte, J.W.M.3
  • 4
    • 54949105397 scopus 로고    scopus 로고
    • Repair and Neurorehabilitation Strategies for Spinal Cord Injury
    • Ruff, R. L.; McKerracher, L.; Selzer, M. E. Repair and Neurorehabilitation Strategies for Spinal Cord Injury Ann. N.Y. Acad. Sci. 2008, 1142, 1-20
    • (2008) Ann. N.Y. Acad. Sci. , vol.1142 , pp. 1-20
    • Ruff, R.L.1    McKerracher, L.2    Selzer, M.E.3
  • 5
    • 36849092335 scopus 로고    scopus 로고
    • Cell therapy for spinal cord regeneration
    • DOI 10.1016/j.addr.2007.08.028, PII S0169409X07002487, Emerging Trends in Cell-Based Therapies
    • Willerth, S. M.; Sakiyama-Elbert, S. E. Cell Therapy for Spinal Cord Regeneration Adv. Drug Delivery Rev. 2008, 60, 263-276 (Pubitemid 350236403)
    • (2008) Advanced Drug Delivery Reviews , vol.60 , Issue.2 , pp. 263-276
    • Willerth, S.M.1    Sakiyama-Elbert, S.E.2
  • 7
    • 0037379348 scopus 로고    scopus 로고
    • Function of Myelin is to Protect Axons from Subsequent Injury: Implications for Deficits in Multiple Sclerosis
    • Rodriguez, M. A Function of Myelin is to Protect Axons from Subsequent Injury: Implications for Deficits in Multiple Sclerosis Brain 2003, 126, 751-752
    • (2003) Brain , vol.126 , pp. 751-752
    • Rodriguez, M.A.1
  • 8
    • 64149099359 scopus 로고    scopus 로고
    • Neuroprotection and Neuroregeneration in Multiple Sclerosis
    • Stangel, M. Neuroprotection and Neuroregeneration in Multiple Sclerosis J. Neurol. 2008, 255 (Suppl 6) 77-81
    • (2008) J. Neurol. , vol.255 , Issue.SUPPL. 6 , pp. 77-81
    • Stangel, M.1
  • 9
    • 18644384444 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived oligodendrocyte progenitor cell transplants remyelinate and restore locomotion after spinal cord injury
    • DOI 10.1523/JNEUROSCI.0311-05.2005
    • Keirstead, H. S.; Nistor, G.; Bernal, G.; Totoiu, M.; Cloutier, F.; Sharp, K.; Steward, O. Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitor Cell Transplants Remyelinate and Restore Locomotion after Spinal Cord Injury J. Neurosci. 2005, 25, 4694-4705 (Pubitemid 40664118)
    • (2005) Journal of Neuroscience , vol.25 , Issue.19 , pp. 4694-4705
    • Keirstead, H.S.1    Nistor, G.2    Bernal, G.3    Totoiu, M.4    Cloutier, F.5    Sharp, K.6    Steward, O.7
  • 10
    • 65249113835 scopus 로고    scopus 로고
    • In Search of Human Oligodendroglia for Myelin Repair
    • Buchet, D.; Baron-Van Evercooren, A. In Search of Human Oligodendroglia for Myelin Repair Neurosci. Lett. 2009, 456, 112-119
    • (2009) Neurosci. Lett. , vol.456 , pp. 112-119
    • Buchet, D.1    Baron-Van Evercooren, A.2
  • 11
    • 1542336187 scopus 로고    scopus 로고
    • Fetal and adult human oligodendrocyte progenitor cell isolates myelinate the congenitally dysmyelinated brain
    • DOI 10.1038/nm974
    • Windrem, M. S.; Nunes, M. C.; Rashbaum, W. K.; Schwartz, T. H.; Goodman, R. A.; McKhann, G., 2nd; Roy, N. S.; Goldman, S. A. Fetal and Adult Human Oligodendrocyte Progenitor Cell Isolates Myelinate the Congenitally Dysmyelinated Brain Nat. Med. 2004, 10, 93-97 (Pubitemid 38524704)
    • (2004) Nature Medicine , vol.10 , Issue.1 , pp. 93-97
    • Windrem, M.S.1    Nunes, M.C.2    Rashbaum, W.K.3    Schwartz, T.H.4    Goodman, R.A.5    McKhann II, G.6    Roy, N.S.7    Goldman, S.A.8
  • 12
    • 80052069403 scopus 로고    scopus 로고
    • (accessed May 20).
    • http://www.geron.com/GRNOPC1Trial/grnopc1-backgrounder.pdf (accessed May 20, 2011).
    • (2011)
  • 13
    • 0345874552 scopus 로고    scopus 로고
    • Transplantation of oligodendrocytes precursors and sonic hedgehog results in improved function and white matter sparing in the cords of adult rats after contusion
    • DOI 10.1016/j.spinee.2003.07.004, PII S1529943003004649
    • Bambakidis, N. C.; Miller, R. H. Transplantation of Oligodendrocyte Precursors and Sonic Hedgehog Results in Improved Function and White Matter Sparing in the Spinal Cords of Adult Rats after Contusion Spine J. 2004, 4, 16-26 (Pubitemid 38100897)
    • (2004) Spine Journal , vol.4 , Issue.1 , pp. 16-26
    • Bambakidis, N.C.1    Miller, R.H.2
  • 14
    • 23044446572 scopus 로고    scopus 로고
    • Functional recovery in traumatic spinal cord injury after transplantation of multineurotrophin-expressing glial-restricted precursor cells
    • DOI 10.1523/JNEUROSCI.1065-05.2005
    • Cao, Q.; Xu, X. M.; DeVries, W. H.; Enzmann, G. U.; Ping, P.; Tsoulfas, P.; Wood, P. M.; Bunge, M. B.; Whittemore, S. R. Functional Recovery in Traumatic Spinal Cord Injury after Transplantation of Multineurotrophin- Expressing Glial-Restricted Precursor Cells J. Neurosci. 2005, 25, 6947-6957 (Pubitemid 41077002)
    • (2005) Journal of Neuroscience , vol.25 , Issue.30 , pp. 6947-6957
    • Cao, Q.1    Xu, X.-M.2    DeVries, W.H.3    Enzmann, G.U.4    Ping, P.5    Tsoulfas, P.6    Wood, P.M.7    Bunge, M.B.8    Whittemore, S.R.9
  • 15
    • 77649133015 scopus 로고    scopus 로고
    • Transplantation of Ciliary Neurotrophic Factor-Expressing Adult Oligodendrocyte Precursor Cells Promotes Remyelination and Functional Recovery after Spinal Cord Injury
    • Cao, Q.; He, Q.; Wang, Y.; Cheng, X.; Howard, R. M.; Zhang, Y.; DeVries, W. H.; Shields, C. B.; Magnuson, D. S.; Xu, X. M. et al. Transplantation of Ciliary Neurotrophic Factor-Expressing Adult Oligodendrocyte Precursor Cells Promotes Remyelination and Functional Recovery after Spinal Cord Injury J. Neurosci. 2010, 30, 2989-3001
    • (2010) J. Neurosci. , vol.30 , pp. 2989-3001
    • Cao, Q.1    He, Q.2    Wang, Y.3    Cheng, X.4    Howard, R.M.5    Zhang, Y.6    Devries, W.H.7    Shields, C.B.8    Magnuson, D.S.9    Xu, X.M.10
  • 16
    • 33646771825 scopus 로고    scopus 로고
    • Remyelination Strategies: New Advancements Toward a Regenerative Treatment in Multiple Sclerosis
    • Stangel, M.; Trebst, C. Remyelination Strategies: New Advancements Toward a Regenerative Treatment in Multiple Sclerosis Curr. Neurol. Neurosci. Rep. 2006, 6, 229-235
    • (2006) Curr. Neurol. Neurosci. Rep. , vol.6 , pp. 229-235
    • Stangel, M.1    Trebst, C.2
  • 17
    • 37849049690 scopus 로고    scopus 로고
    • Regeneration and Repair in Multiple Sclerosis: The View from Experimental Pathology
    • Blakemore, W. F. Regeneration and Repair in Multiple Sclerosis: the View from Experimental Pathology J. Neurol. Sci. 2008, 265, 1-4
    • (2008) J. Neurol. Sci. , vol.265 , pp. 1-4
    • Blakemore, W.F.1
  • 19
    • 3042754210 scopus 로고    scopus 로고
    • In vitro myelination by oligodendrocyte precursor cells transfected with the neurotrophin-3 gene
    • DOI 10.1002/glia.20035
    • Rubio, N.; Rodriguez, R.; Arevalo, M. A. In Vitro Myelination by Oligodendrocyte Precursor Cells Transfected with the Neurotrophin-3 Gene Glia 2004, 47, 78-87 (Pubitemid 38879708)
    • (2004) GLIA , vol.47 , Issue.1 , pp. 78-87
    • Rubio, N.1    Rodriguez, R.2    Arevalo, M.A.3
  • 20
    • 0035885111 scopus 로고    scopus 로고
    • Transplants of cells genetically modified to express neurotrophin-3 rescue axotomized Clarke's nucleus neurons after spinal cord hemisection in adult rats
    • DOI 10.1002/jnr.1185
    • Himes, B. T.; Liu, Y.; Solowska, J. M.; Snyder, E. Y.; Fischer, I.; Tessler, A. Transplants of Cells Genetically Modified to Express Neurotrophin-3 Rescue Axotomized Clarke's Nucleus Neurons after Spinal Cord Hemisection in Adult Rats J. Neurosci. Res. 2001, 65, 549-564 (Pubitemid 32847148)
    • (2001) Journal of Neuroscience Research , vol.65 , Issue.6 , pp. 549-564
    • Timothy Himes, B.1    Liu, Y.2    Solowska, J.M.3    Snyder, E.Y.4    Fischer, I.5    Tessler, A.6
  • 22
    • 0029123286 scopus 로고
    • CNS-Derived Neural Progenitor Cells for Gene Transfer of Nerve Growth Factor to the Adult Rat brain: Complete Rescue of Axotomized Cholinergic Neurons after Transplantation into the Septum
    • Martinez-Serrano, A.; Lundberg, C.; Horellou, P.; Fischer, W.; Bentlage, C.; Campbell, K.; McKay, R. D.; Mallet, J.; Bjorklund, A. CNS-Derived Neural Progenitor Cells for Gene Transfer of Nerve Growth Factor to the Adult Rat brain: Complete Rescue of Axotomized Cholinergic Neurons after Transplantation into the Septum J. Neurosci. 1995, 15, 5668-5680
    • (1995) J. Neurosci. , vol.15 , pp. 5668-5680
    • Martinez-Serrano, A.1    Lundberg, C.2    Horellou, P.3    Fischer, W.4    Bentlage, C.5    Campbell, K.6    McKay, R.D.7    Mallet, J.8    Bjorklund, A.9
  • 23
    • 38049101110 scopus 로고    scopus 로고
    • Transplantation of Adult Neural Progenitor Cells Transfected with Vascular Endothelial Growth Factor Rescues Grafted Cells in the Rat Brain
    • Maurer, M. H.; Thomas, C.; Burgers, H. F.; Kuschinsky, W. Transplantation of Adult Neural Progenitor Cells Transfected with Vascular Endothelial Growth Factor Rescues Grafted Cells in the Rat Brain Int. J. Biol. Sci. 2007, 4, 1-7
    • (2007) Int. J. Biol. Sci. , vol.4 , pp. 1-7
    • Maurer, M.H.1    Thomas, C.2    Burgers, H.F.3    Kuschinsky, W.4
  • 24
    • 0032528159 scopus 로고    scopus 로고
    • Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord
    • McTigue, D. M.; Horner, P. J.; Stokes, B. T.; Gage, F. H. Neurotrophin-3 and Brain-Derived Neurotrophic Factor Induce Oligodendrocyte Proliferation and Myelination of Regenerating Axons in the Contused Adult Rat Spinal Cord J. Neurosci. 1998, 18, 5354-5365 (Pubitemid 28311952)
    • (1998) Journal of Neuroscience , vol.18 , Issue.14 , pp. 5354-5365
    • McTigue, D.M.1    Horner, P.J.2    Stokes, B.T.3    Gage, F.H.4
  • 25
    • 33646576504 scopus 로고    scopus 로고
    • Direct gene therapy for repair of the spinal cord
    • DOI 10.1089/neu.2006.23.508
    • Blits, B.; Bunge, M. B. Direct Gene Therapy for Repair of the Spinal Cord J. Neurotrauma 2006, 23, 508-520 (Pubitemid 43726325)
    • (2006) Journal of Neurotrauma , vol.23 , Issue.3-4 , pp. 508-520
    • Blits, B.1    Bunge, M.B.2
  • 26
    • 34249656320 scopus 로고    scopus 로고
    • Process elongation of oligodendrocytes is promoted by the Kelch-related protein MRP2/KLHL1
    • DOI 10.1074/jbc.M701019200
    • Jiang, S.; Seng, S.; Avraham, H. K.; Fu, Y.; Avraham, S. Process Elongation of Oligodendrocytes is Promoted by the Kelch-Related Protein MRP2/KLHL1 J. Biol. Chem. 2007, 282, 12319-12329 (Pubitemid 47100730)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.16 , pp. 12319-12329
    • Jiang, S.1    Seng, S.2    Avraham, H.K.3    Fu, Y.4    Avraham, S.5
  • 27
    • 0032869846 scopus 로고    scopus 로고
    • Adenoviral vectors for in vivo gene delivery to oligodendrocytes: Transgene expression and cytopathic consequences
    • DOI 10.1038/sj.gt.3300971
    • Franklin, R.; Quick, M.; Haase, G. Adenoviral Vectors for in Vivo Gene Delivery to Oligodendrocytes: Transgene Expression and Cytopathic Consequences Gene Ther. 1999, 6, 1360-1367 (Pubitemid 29396724)
    • (1999) Gene Therapy , vol.6 , Issue.8 , pp. 1360-1367
    • Franklin, R.J.M.1    Quick, M.M.2    Haase, G.3
  • 28
    • 0031802635 scopus 로고    scopus 로고
    • Viral vectors, tools for gene transfer in the nervous system
    • DOI 10.1016/S0301-0082(98)00007-0, PII S0301008298000070
    • Hermens, W. T.; Verhaagen, J. Viral Vectors, Tools for Gene Transfer in the Nervous System Prog. Neurobiol. 1998, 55, 399-432 (Pubitemid 28255043)
    • (1998) Progress in Neurobiology , vol.55 , Issue.4 , pp. 399-432
    • Hermens, W.T.J.M.C.1    Verhaagen, J.2
  • 29
    • 66949127647 scopus 로고    scopus 로고
    • Uptake of Systemically Administered Magnetic Nanoparticles (MNPs) in Areas of Experimental Spinal Cord Injury (SCI)
    • Jeffery, N. D.; McBain, S. C.; Dobson, J.; Chari, D. M. Uptake of Systemically Administered Magnetic Nanoparticles (MNPs) in Areas of Experimental Spinal Cord Injury (SCI) J. Tissue Eng. Regen. Med. 2009, 3, 153-157
    • (2009) J. Tissue Eng. Regen. Med. , vol.3 , pp. 153-157
    • Jeffery, N.D.1    McBain, S.C.2    Dobson, J.3    Chari, D.M.4
  • 30
    • 0031888001 scopus 로고    scopus 로고
    • Transient transfection of oligodendrocyte progenitors by electroporation
    • DOI 10.1023/A:1022426021173
    • Krueger, W. H.; Madison, D. L.; Pfeiffer, S. E. Transient Transfection of Oligodendrocyte Progenitors by Electroporation Neurochem. Res. 1998, 23, 421-426 (Pubitemid 28109889)
    • (1998) Neurochemical Research , vol.23 , Issue.3 , pp. 421-426
    • Krueger, W.H.H.1    Madison, D.L.2    Pfeiffer, S.E.3
  • 31
    • 77957343707 scopus 로고    scopus 로고
    • Chemical Vectors for Gene Delivery: Uptake and Intracellular Trafficking
    • Pichon, C.; Billiet, L.; Midoux, P. Chemical Vectors for Gene Delivery: Uptake and Intracellular Trafficking Curr. Opin. Biotechnol. 2010, 21, 640-645
    • (2010) Curr. Opin. Biotechnol. , vol.21 , pp. 640-645
    • Pichon, C.1    Billiet, L.2    Midoux, P.3
  • 32
    • 33847706008 scopus 로고    scopus 로고
    • Translational considerations for CNS gene therapy
    • DOI 10.1517/14712598.7.3.305
    • Ryan, D. A.; Federoff, H, J. Translational Considerations for CNS Gene Therapy Expert Opin. Biol. Ther. 2007, 7, 305-318 (Pubitemid 46383474)
    • (2007) Expert Opinion on Biological Therapy , vol.7 , Issue.3 , pp. 305-318
    • Ryan, D.A.1    Federoff, H.J.2
  • 33
    • 0030024584 scopus 로고    scopus 로고
    • Efficient and sustained transgene expression in mature rat oligodendrocytes in primary culture
    • DOI 10.1002/jnr.490430104
    • Guo, Z.; Yang, N. S.; Jiao, S.; Sun, J.; Cheng, L.; Wolff, J. A.; Duncan, I. D. Efficient and Sustained Transgene Expression in Mature Rat Oligodendrocytes in Primary Culture J. Neurosci. Res. 1996, 43, 32-41 (Pubitemid 26044215)
    • (1996) Journal of Neuroscience Research , vol.43 , Issue.1 , pp. 32-41
    • Guo, Z.1    Yang, N.-S.2    Jiao, S.3    Sun, J.4    Cheng, L.5    Wolff, J.A.6    Duncan, I.D.7
  • 34
    • 70450207654 scopus 로고    scopus 로고
    • Progress in Functionalization of Magnetic Nanoparticles for Applications in Biomedicine
    • Berry, C. C. Progress in Functionalization of Magnetic Nanoparticles for Applications in Biomedicine J. Phys. D: Appl. Phys. 2009, 42, 1-9
    • (2009) J. Phys. D: Appl. Phys. , vol.42 , pp. 1-9
    • Berry, C.C.1
  • 35
    • 33947136251 scopus 로고    scopus 로고
    • Magnetic Micro- and Nano-Particle-Based Targeting for Drug and Gene Delivery
    • Dobson, J. Magnetic Micro- and Nano-Particle-Based Targeting for Drug and Gene Delivery Nanomedicine (London) 2006, 1, 31-37
    • (2006) Nanomedicine (London) , vol.1 , pp. 31-37
    • Dobson, J.1
  • 37
    • 78149414882 scopus 로고    scopus 로고
    • The Use of Magnetite Nanoparticles for Implant-Assisted Magnetic Drug Targeting in Thrombolytic Therapy
    • Kempe, M; Kempe, H; Snowball, I.; Wallen, R.; Arza, C. R.; Gotberg, M.; Olsson, T. The Use of Magnetite Nanoparticles for Implant-Assisted Magnetic Drug Targeting in Thrombolytic Therapy Biomaterials 2010, 31, 9499-9510
    • (2010) Biomaterials , vol.31 , pp. 9499-9510
    • Kempe, M.1    Kempe, H.2    Snowball, I.3    Wallen, R.4    Arza, C.R.5    Gotberg, M.6    Olsson, T.7
  • 39
  • 40
    • 73549120413 scopus 로고    scopus 로고
    • Preparation and Characterization of Polyethylenimine-Coated Fe3O4-MCM-48 Nanocomposite Particles as a Novel Agent for Magnet-Assisted Transfection
    • Yiu, H. H.; McBain, S. C.; Lethbridge, Z. A.; Lees, M. R.; Dobson, J. Preparation and Characterization of Polyethylenimine-Coated Fe3O4-MCM-48 Nanocomposite Particles as a Novel Agent for Magnet-Assisted Transfection J. Biomed. Mater. Res. A 2010, 92, 386-392
    • (2010) J. Biomed. Mater. Res. A , vol.92 , pp. 386-392
    • Yiu, H.H.1    McBain, S.C.2    Lethbridge, Z.A.3    Lees, M.R.4    Dobson, J.5
  • 41
    • 40949137366 scopus 로고    scopus 로고
    • Synthesis of chemically functionalized superparamagnetic nanoparticles as delivery vectors for chemotherapeutic drugs
    • DOI 10.1016/j.bmc.2007.12.051, PII S0968089607011200
    • Hanessian, S.; Grzyb, J. A.; Cengelli, F.; Juillerat-Jeanneret, L. Synthesis of Chemically Functionalized Superparamagnetic Nanoparticles as Delivery Vectors for Chemotherapeutic Drugs Bioorg. Med. Chem. 2008, 16, 2921-2931 (Pubitemid 351418211)
    • (2008) Bioorganic and Medicinal Chemistry , vol.16 , Issue.6 , pp. 2921-2931
    • Hanessian, S.1    Grzyb, J.A.2    Cengelli, F.3    Juillerat-Jeanneret, L.4
  • 42
    • 7744247184 scopus 로고    scopus 로고
    • Superparamagnetic iron oxide-labeled schwann cells and olfactory ensheathing cells can be traced in vivo by magnetic resonance imaging and retain functional properties after transplantation into the CNS
    • DOI 10.1523/JNEUROSCI.3126-04.2004
    • Dunning, M. D.; Lakatos, A.; Loizou, L.; Kettunen, M.; ffrench-Constant, C.; Brindle, K. M.; Franklin, R. J. M. Superparamagnetic Iron Oxide-Labeled Schwann Cells and Olfactory Ensheathing Cells can be Traced in Vivo by Magnetic Resonance Imaging and Retain Functional Properties after Transplantation into the CNS J. Neurosci. 2004, 24, 9799-9810 (Pubitemid 39463561)
    • (2004) Journal of Neuroscience , vol.24 , Issue.44 , pp. 9799-9810
    • Dunning, M.D.1    Lakatos, A.2    Loizou, L.3    Kettunen, M.4    Ffrench-Constant, C.5    Brindle, K.M.6    Franklin, R.J.M.7
  • 44
    • 79954490740 scopus 로고    scopus 로고
    • Nucleic Acid Delivery Using Magnetic Nanoparticles: The Magnetofection Technology
    • Laurent, N.; Sapet, C.; Le Gourrierec, L.; Bertosio, E.; Zelphati, O. Nucleic Acid Delivery Using Magnetic Nanoparticles: the Magnetofection Technology Ther. Delivery 2011, 2, 471-482
    • (2011) Ther. Delivery , vol.2 , pp. 471-482
    • Laurent, N.1    Sapet, C.2    Le Gourrierec, L.3    Bertosio, E.4    Zelphati, O.5
  • 47
    • 85047695405 scopus 로고    scopus 로고
    • Magnetofection: Enhancing and targeting gene delivery by magnetic force in vitro and in vivo
    • DOI 10.1038/sj/gt/3301624
    • Scherer, F.; Anton, M.; Schillinger, U.; Henke, J.; Bergemann, C.; Kruger, A.; Gansbacher, B.; Plank, C. Magnetofection: Enhancing and Targeting Gene Delivery by Magnetic Force in Vitro and in Vivo Gene Ther. 2002, 9, 102-109 (Pubitemid 34189525)
    • (2002) Gene Therapy , vol.9 , Issue.2 , pp. 102-109
    • Scherer, F.1    Anton, M.2    Schillinger, U.3    Henke, J.4    Bergemann, C.5    Kruger, A.6    Gansbacher, B.7    Plank, C.8
  • 48
    • 13644257020 scopus 로고    scopus 로고
    • Insights into the mechanism of magnetofection using PEI-based magnetofectins for gene transfer
    • DOI 10.1002/jgm.577
    • Huth, S.; Lausier, J.; Gersting, S. W.; Rudolph, C.; Plank, C.; Welsch, U.; Rosenecker, J. Insights into the Mechanism of Magnetofection using PEI-based Magnetofectins for Gene Transfer J. Gene Med. 2004, 6, 923-936 (Pubitemid 40228108)
    • (2004) Journal of Gene Medicine , vol.6 , Issue.8 , pp. 923-936
    • Huth, S.1    Lausier, J.2    Gersting, S.W.3    Rudolph, C.4    Plank, C.5    Welsch, U.6    Rosenecker, J.7
  • 49
    • 33644593889 scopus 로고    scopus 로고
    • Uptake Pathways and Subsequent Intracellular Trafficking in Nonviral Gene Delivery
    • Khalil, I. A.; Kogure, K.; Akita, H.; Harashima, H. Uptake Pathways and Subsequent Intracellular Trafficking in Nonviral Gene Delivery Pharmacol. Rev. 2006, 58, 32-45
    • (2006) Pharmacol. Rev. , vol.58 , pp. 32-45
    • Khalil, I.A.1    Kogure, K.2    Akita, H.3    Harashima, H.4
  • 51
    • 0037237133 scopus 로고    scopus 로고
    • Magnetofection: Enhancing and targeting gene delivery with superparamagnetic nanoparticles and magnetic fields
    • DOI 10.1081/LPR-120017486
    • Plank, C.; Scherer, F.; Schillinger, U.; Bergemann, C.; Anton, M. Magnetofection: Enhancing and Targeting Gene Delivery with Superparamagnetic Nanoparticles and Magnetic Fields J. Liposome Res. 2003, 13, 29-32 (Pubitemid 36373341)
    • (2003) Journal of Liposome Research , vol.13 , Issue.1 , pp. 29-32
    • Plank, C.1    Scherer, F.2    Schillinger, U.3    Bergemann, C.4    Anton, M.5
  • 52
    • 77949657067 scopus 로고    scopus 로고
    • The Effect of Static Magnetic Fields and tat Peptides on Cellular and Nuclear Uptake of Magnetic Nanoparticles
    • Smith, C. A.; de la Fuente, J.; Pelaz, B.; Furlani, E. P.; Mullin, M.; Berry, C. C. The Effect of Static Magnetic Fields and tat Peptides on Cellular and Nuclear Uptake of Magnetic Nanoparticles Biomaterials 2010, 31, 4392-4400
    • (2010) Biomaterials , vol.31 , pp. 4392-4400
    • Smith, C.A.1    De La Fuente, J.2    Pelaz, B.3    Furlani, E.P.4    Mullin, M.5    Berry, C.C.6
  • 53
    • 77950875686 scopus 로고    scopus 로고
    • Enhancement of Magnetic Nanoparticle-Mediated Gene Transfer to Astrocytes by "magnetofection": Effects of Static and Oscillating Fields
    • Pickard, M. R.; Chari, D. M. Enhancement of Magnetic Nanoparticle- Mediated Gene Transfer to Astrocytes by "Magnetofection": Effects of Static and Oscillating Fields Nanomedicine (London) 2010, 5, 217-232
    • (2010) Nanomedicine (London) , vol.5 , pp. 217-232
    • Pickard, M.R.1    Chari, D.M.2
  • 54
    • 80052055762 scopus 로고    scopus 로고
    • Programme of the Fourth Annual Scientific Conference of the UK National Stem Cell Network, University of York, March 30-April 1, Abstract: Poster number 83.
    • Pickard, M. R.; Chari, D. M. Magnetic Nanoparticle Applications for Neural Stem Cell Transplantation Therapies. Programme of the Fourth Annual Scientific Conference of the UK National Stem Cell Network, University of York, March 30-April 1, 2011. Abstract: Poster number 83.
    • (2011) Magnetic Nanoparticle Applications for Neural Stem Cell Transplantation Therapies
    • Pickard, M.R.1    Chari, D.M.2
  • 55
    • 78751705386 scopus 로고    scopus 로고
    • The Transfection of Multipotent Neural Precursor/Stem Cell Transplant Populations with Magnetic Nanoparticles
    • Pickard, M. R.; Barraud, P.; Chari, D. M. The Transfection of Multipotent Neural Precursor/Stem Cell Transplant Populations with Magnetic Nanoparticles Biomaterials 2011, 32, 2274-2284
    • (2011) Biomaterials , vol.32 , pp. 2274-2284
    • Pickard, M.R.1    Barraud, P.2    Chari, D.M.3
  • 56
    • 0025652651 scopus 로고
    • Gene Transfer of Rat Mature Oligodendrocytes and Glial Progenitor Cells with the LacZ Gene
    • Lubetzki, C.; Goujet-Zalc, C.; Evrard, C.; Danos, O.; Rouget, P.; Zalc, B. Gene Transfer of Rat Mature Oligodendrocytes and Glial Progenitor Cells with the LacZ Gene Ann. N.Y. Acad. Sci. 1990, 605, 66-70
    • (1990) Ann. N.Y. Acad. Sci. , vol.605 , pp. 66-70
    • Lubetzki, C.1    Goujet-Zalc, C.2    Evrard, C.3    Danos, O.4    Rouget, P.5    Zalc, B.6
  • 57
    • 80052049219 scopus 로고    scopus 로고
    • (accessed May 20).
    • http://www.lonzabio.com/fileadmin/groups/marketing/Downloads/Protocols/ Generated/Optimized-Protocol-99.pdf (accessed May 20, 2011).
    • (2011)
  • 59
    • 51349087646 scopus 로고    scopus 로고
    • Magnetic Nanoparticles as Gene Delivery Agents: Enhanced Transfection in the Presence of Oscillating Magnet Arrays
    • McBain, S. C.; Griesenbach, U.; Xenariou, S.; Keramane, A.; Batich, C. D.; Alton, E. W. F. W.; Dobson, J. Magnetic Nanoparticles as Gene Delivery Agents: Enhanced Transfection in the Presence of Oscillating Magnet Arrays Nanotechnology 2008, 19, 405102
    • (2008) Nanotechnology , vol.19 , pp. 405102
    • McBain, S.C.1    Griesenbach, U.2    Xenariou, S.3    Keramane, A.4    Batich, C.D.5    Alton, E.W.F.W.6    Dobson, J.7
  • 60
    • 0035066639 scopus 로고    scopus 로고
    • Biology of oligodendrocyte and myelin in the mammalian central nervous system
    • Baumann, N.; Pham-Dinh, D. Biology of Oligodendrocyte and Myelin in the Mammalian Central Nervous System Physiol. Rev. 2001, 81, 871-927 (Pubitemid 32267079)
    • (2001) Physiological Reviews , vol.81 , Issue.2 , pp. 871-927
    • Baumann, N.1    Pham-Dinh, D.2
  • 61
    • 34248657276 scopus 로고    scopus 로고
    • Remyelination in Multiple Sclerosis
    • Chari, D. M. Remyelination in Multiple Sclerosis Int. Rev. Neurobiol. 2007, 79, 589-620
    • (2007) Int. Rev. Neurobiol. , vol.79 , pp. 589-620
    • Chari, D.M.1
  • 62
    • 23844458963 scopus 로고    scopus 로고
    • The molecular orchestra of the migration of oligodendrocyte precursors during development
    • DOI 10.1016/j.brainresrev.2004.12.034, PII S0165017304002152, Embryonic Chimeras and Transplantation for the Study of CNS Development and Regeneration
    • de Castro, F.; Bribian, A. The Molecular Orchestra of the Migration of Oligodendrocyte Precursors During Development Brain Res. Rev. 2005, 49, 227-241 (Pubitemid 41160392)
    • (2005) Brain Research Reviews , vol.49 , Issue.2 , pp. 227-241
    • De Castro, F.1    Bribian, A.2
  • 63
    • 0034029228 scopus 로고    scopus 로고
    • PDGF and FGF-2 signaling in oligodendrocyte progenitor cells: Regulation of proliferation and differentiation by multiple intracellular signaling pathways
    • DOI 10.1006/mcne.1999.0827
    • Baron, W.; Metz, B.; Bansal, R.; Hoekstra, D.; de Vries, H. PDGF and FGF-2 Signaling in Oligodendrocyte Progenitor Cells: Regulation of Proliferation and Differentiation by Multiple Intracellular Signaling Pathways Mol. Cell. Neurosci. 2000, 15, 314-329 (Pubitemid 30193804)
    • (2000) Molecular and Cellular Neurosciences , vol.15 , Issue.3 , pp. 314-329
    • Baron, W.1    Metz, B.2    Bansal, R.3    Hoekstra, D.4    De Vries, H.5
  • 65
    • 22044448897 scopus 로고    scopus 로고
    • Organotypic cultures as tools for functional screening in the CNS
    • DOI 10.1016/S1359-6446(05)03502-6, PII S1359644605035026
    • Sundstrom, L.; Morrison, B., 3rd; Bradley, M.; Pringle, A. Organotypic Cultures as Tools for Functional Screening in the CNS Drug Discovery Today 2005, 10, 993-1000 (Pubitemid 40967048)
    • (2005) Drug Discovery Today , vol.10 , Issue.14 , pp. 993-1000
    • Sundstrom, L.1    Morrison III, B.2    Bradley, M.3    Pringle, A.4
  • 66
    • 57449087848 scopus 로고    scopus 로고
    • Simvastatin Induces Cell Death in a Mouse Cerebellar Slice Culture (CSC) Model of Developmental Myelination
    • Xiang, Z.; Reeves, S. A. Simvastatin Induces Cell Death in a Mouse Cerebellar Slice Culture (CSC) Model of Developmental Myelination Exp. Neurol. 2009, 215, 41-47
    • (2009) Exp. Neurol. , vol.215 , pp. 41-47
    • Xiang, Z.1    Reeves, S.A.2
  • 67
    • 4744349978 scopus 로고    scopus 로고
    • Lysolecithin induces demyelination in vitro in a cerebellar slice culture system
    • DOI 10.1002/jnr.20248
    • Birgbauer, E.; Rao, T. S.; Webb, M. Lysolecithin Induces Demyelination in Vitro in a Cerebellar Slice Culture System J. Neurosci. Res. 2004, 78, 157-166 (Pubitemid 39313787)
    • (2004) Journal of Neuroscience Research , vol.78 , Issue.2 , pp. 157-166
    • Birgbauer, E.1    Rao, T.S.2    Webb, M.3
  • 68
    • 33745776536 scopus 로고    scopus 로고
    • Skin-derived precursors generate myelinating Schwann cells for the injured and dysmyelinated nervous system
    • DOI 10.1523/JNEUROSCI.1007-06.2006
    • McKenzie, I. A.; Biernaskie, J.; Toma, J. G.; Midha, R.; Miller, F. D. Skin-Derived Precursors Generate Myelinating Schwann Cells for the Injured and Dysmyelinated Nervous System J. Neurosci. 2006, 26, 6651-6660 (Pubitemid 44318347)
    • (2006) Journal of Neuroscience , vol.26 , Issue.24 , pp. 6651-6660
    • McKenzie, I.A.1    Biernaskie, J.2    Toma, J.G.3    Midha, R.4    Miller, F.D.5
  • 69
    • 33644966032 scopus 로고    scopus 로고
    • Impact of Basic FGF Expression in Astrocytes on Dopamine Neuron Synaptic Function and Development
    • Forget, C.; Stewart, J; Trudeau, L.-E. Impact of Basic FGF Expression in Astrocytes on Dopamine Neuron Synaptic Function and Development Eur. J. Neurosci. 2006, 23, 608-616
    • (2006) Eur. J. Neurosci. , vol.23 , pp. 608-616
    • Forget, C.1    Stewart, J.2    Trudeau, L.-E.3
  • 70
    • 0028933272 scopus 로고
    • Regulation of Astrocyte Proliferation by FGF-2 and Heparan Sulfate in Vivo
    • Gomez-Pinilla, F.; Vu, L.; Cotman, C. W. Regulation of Astrocyte Proliferation by FGF-2 and Heparan Sulfate in Vivo J. Neurosci. 1995, 15, 2021-2029
    • (1995) J. Neurosci. , vol.15 , pp. 2021-2029
    • Gomez-Pinilla, F.1    Vu, L.2    Cotman, C.W.3
  • 71
    • 0019313317 scopus 로고
    • Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
    • DOI 10.1083/jcb.85.3.890
    • McCarthy, K. D.; de Vellis, J. Preparation of Separate Astroglial and Oligodendroglial Cell Cultures from Rat Cerebral Tissue J. Cell Biol. 1980, 85, 890-902 (Pubitemid 10007455)
    • (1980) Journal of Cell Biology , vol.85 , Issue.3 , pp. 890-902
    • McCarthy, K.D.1    De Vellis, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.