Time course of lung retention and toxicity of inhaled particles: Short-term exposure to nano-Ceria

Archives of Toxicology

Volumn 88, Issue 11, 2014, Pages 2033-2059

  Keller, Jana ^a   Wohlleben, Wendel ^a   Ma Hock, Lan ^a   Strauss, Volker ^a   Gröters, Sibylle ^a   Küttler, Karin ^a   Wiench, Karin ^a   Herden, Christiane ^b   Oberdörster, Günter ^c   van Ravenzwaay, Bennard ^a   Landsiedel, Robert ^a  

^a BASF SE   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c UNIVERSITY OF ROCHESTER   (United States)

Author keywords

Bronchoalveolar lavage; Ceria; Inhalation; Nanomaterial (NM); Respiratory tract

Indexed keywords

CERIUM OXIDE; CERIUM OXIDE NM 211; CERIUM OXIDE NM 212; NANOPARTICLE; UNCLASSIFIED DRUG; AEROSOL; CERIC OXIDE; CERIUM; NANOMATERIAL;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CHRONICITY; CLINICAL CHEMISTRY; CLINICAL EXAMINATION; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; GENOTOXICITY; GRANULOMATOUS INFLAMMATION; HEMATOLOGY; HISTOPATHOLOGY; INHALATION; LUNG BURDEN; LUNG CLEARANCE; LUNG LAVAGE; LUNG TOXICITY; LYMPH NODE; MACROPHAGE; NANOTOXICOLOGY; NEUTROPHIL; NONHUMAN; ORGAN WEIGHT; PROTEIN BLOOD LEVEL; RAT; UPPER RESPIRATORY TRACT; ADVERSE EFFECTS; ANIMAL; CHEMICALLY INDUCED; COMPARATIVE STUDY; DOSE RESPONSE; EXPOSURE; FEMALE; GRANULOMA; INFLAMMATION; INHALATIONAL DRUG ADMINISTRATION; LUNG; METABOLISM; PATHOLOGY; TIME; WISTAR RAT;

RATTUS;

ADMINISTRATION, INHALATION; AEROSOLS; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CERIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GRANULOMA; INFLAMMATION; INHALATION EXPOSURE; LUNG; MACROPHAGES; NANOSTRUCTURES; NEUTROPHILS; RATS; RATS, WISTAR; TIME FACTORS;

EID: 84919834694     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-014-1349-9     Document Type: Article

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