Netrin-1 improves post-injury cardiac function in vivo via DCC/NO-dependent preservation of mitochondrial integrity, while attenuating autophagy

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1852, Issue 2, 2015, Pages 277-289

  Bouhidel, Jalaleddinne Omar ^a   Wang, Ping ^a   Siu, Kin Lung ^a   Li, Hong ^a   Youn, Ji Youn ^a   Cai, Hua ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Autophagy; Ischemia reperfusion (I R) injury; Myocardial infarction (MI); NADPH oxidase isoforms 4 (NOX4); Netrin 1; Nitric oxide (NO)

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; NETRIN 1; NITRIC OXIDE; SUPEROXIDE; UO 126; CARDIOTONIC AGENT; CELL SURFACE RECEPTOR; DCC PROTEIN, MOUSE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NERVE GROWTH FACTOR; NETRIN-1; NOX4 PROTEIN, MOUSE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TUMOR SUPPRESSOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; BIOAVAILABILITY; CONTROLLED STUDY; CORONARY ARTERY LIGATION; CORONARY ARTERY OCCLUSION; ELECTRON SPIN RESONANCE; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART PROTECTION; IN VIVO STUDY; MALE; MITOCHONDRION SWELLING; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; REPERFUSION INJURY; ANIMAL; C57BL MOUSE; DOWN REGULATION; ENZYME ACTIVATION; ENZYMOLOGY; HEART FUNCTION TEST; METABOLISM; MITOCHONDRION; PATHOLOGY; PATHOPHYSIOLOGY; VASCULAR REMODELING;

MUS;

ANIMALS; AUTOPHAGY; CARDIOTONIC AGENTS; DOWN-REGULATION; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEART FUNCTION TESTS; MALE; MICE, INBRED C57BL; MITOCHONDRIA; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; NADPH OXIDASE; NERVE GROWTH FACTORS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; RECEPTORS, CELL SURFACE; SUPEROXIDES; TUMOR SUPPRESSOR PROTEINS; VASCULAR REMODELING;

EID: 84919829116     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2014.06.005     Document Type: Article

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