Radiochemotherapy-induced changes of tumour vascularity and blood supply estimated by dynamic contrast-enhanced CT and fractal analysis in malignant head and neck tumours

British Journal of Radiology

Volumn 88, Issue 1045, 2015, Pages

  Abramyuk, Andrij ^a   Hietschold, V ^a   Appold, S ^a   Von Kummer, R ^a   Abolmaali, N ^a  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; FLUOROURACIL; IOPROMIDE; CONTRAST MEDIUM;

ADULT; AGED; ARTICLE; CHEMORADIOTHERAPY; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DYNAMIC CONTRAST ENHANCED COMPUTER ASSISTED TOMOGRAPHY; FOLLOW UP; FRACTAL ANALYSIS; HUMAN; HYPOPHARYNX CARCINOMA; MULTIPLE CYCLE TREATMENT; OROPHARYNX CARCINOMA; SQUAMOUS CELL CARCINOMA; TREATMENT RESPONSE; TUMOR VASCULARIZATION; TUMOR VOLUME; FEMALE; HEAD AND NECK NEOPLASMS; MALE; MIDDLE AGED; PROCEDURES; PROSPECTIVE STUDY; RADIOGRAPHY; SPIRAL COMPUTER ASSISTED TOMOGRAPHY; VASCULARIZATION;

AGED; CHEMORADIOTHERAPY; CONTRAST MEDIA; FEMALE; FOLLOW-UP STUDIES; FRACTALS; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; TOMOGRAPHY, SPIRAL COMPUTED;

EID: 84919774826     PISSN: 00071285     EISSN: None     Source Type: Journal    
DOI: 10.1259/bjr.20140412     Document Type: Article

References (42)

1. Pazdur R, Coia L, Hoskins W, Wagman L, eds. Cancer management: a multidisciplinary approach. 9th edn. New York, NY: CMP Healthcare Media; 2005.
2. Gorski DH, Beckett MA, Jaskowiak NT, Calvin DP, Mauceri HJ, Salloum RM, et al. Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation. Cancer Res 1999; 59: 3374-8.
3. Koukourakis MI, Giatromanolaki A, Sivridis E, Simopoulos K, Pissakas G, Gatter KC, et al. Squamous cell head and neck cancer: evidence of angiogenic regeneration during radiotherapy. Anticancer Res 2001; 21: 4301-9.
4. Albertsson P, Lennernäs B, Norrby K. Chemotherapy and antiangiogenesis: drug-specific effects on microvessel sprouting. Apmis 2003; 111: 995-1003.
5. Folkman J, Camphausen K. Cancer. What does radiotherapy do to endothelial cells? Science 2001; 293: 227-8.
6. Furuya M, Nishiyama M, Kasuya Y, Kimura S, Ishikura H. Pathophysiology of tumor neovascularization. Vasc Health Risk Manag 2005; 1: 277-90.
7. Wouters BG, Brown JM. Cells at intermediate oxygen levels can be more important than the "hypoxic fraction" in determining tumor response to fractionated radiotherapy. Radiat Res 1997; 147: 541-50.
8. Bocci G, Nicolaou KC, Kerbel RS. Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs. Cancer Res 2002; 62: 6938-43.
9. Hara T, Bansal A, DeGrado TR. Effect of hypoxia on the uptake of [methyl-3H] choline, [1-14C] acetate and [18F]FDG in cultured prostate cancer cells. Nucl Med Biol 2006; 33: 977-84.
10. Marusyk A, Polyak K. Tumor heterogeneity: causes and consequences. Biochim Biophys Acta 2010; 1805: 105-17. doi: 10.1016/j.bbcan.2009.11.002
11. Fidler IJ, Hart IR. Biological diversity in metastatic neoplasms: origins and implications. Science 1982; 217: 998-1003.
12. Heppner GH. Tumor heterogeneity. Cancer Res 1984; 44: 2259-65.
13. Van der Meeren A, Monti P, Vandamme M, Squiban C, Wysocki J, Griffiths N. Abdominal radiation exposure elicits inflammatory responses and abscopal effects in the lungs of mice. Radiat Res 2005; 163: 144-52.
14. Abramyuk A, Tokalov S, Zophel K, Koch A, Szluha Lazanyi K, Gillham C, et al. Is pre-therapeutical FDG-PET/CT capable to detect high risk tumor subvolumes responsible for local failure in non-small cell lung cancer? Radiother Oncol 2009; 91: 399-404. doi: 10.1016/j.radonc.2009.01.003
15. Benjamin LE, Golijanin D, Itin A, Pode D, Keshet E. Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal. J Clin Invest 1999; 103: 159-65.
16. Srinivasan A, Mohan S, Mukherji SK. Biologic imaging of head and neck cancer: the present and the future. AJNR Am J Neuroradiol 2012; 33: 586-94. doi: 10.3174/ajnr.A2535
17. Miles KA, Charnsangavej C, Lee FT, Fishman EK, Horton K, Lee TY. Application of CT in the investigation of angiogenesis in oncology. Acad Radiol 2000; 7: 840-50.
18. Abramyuk A, Wolf G, Shakirin G, Haberland U, Tokalov S, Koch A, et al. Preliminary assessment of dynamic contrast-enhanced CT implementation in pretreatment FDG-PET/CT for outcome prediction in head and neck tumors. Acta Radiol 2010; 51: 793-9. doi: 10.3109/02841851.2010.491092
19. WHO handbook for reporting results of cancer treatment. Offset publication no. 48. Geneva, Switzerland: World Health Organization; 1979.
20. Tofts PS, Brix G, Buckley DL, Evelhoch JL, Henderson E, Knopp MV, et al. Estimating kinetic parameters from dynamic contrastenhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols. J Magn Reson Imaging 1999; 10: 223-32.
21. Patankar TF, Haroon HA, Mills SJ, Balériaux D, Buckley DL, Parker GJ, et al. Is volume transfer coefficient (K(trans)) related to histologic grade in human gliomas? AJNR Am J Neuroradiol 2005; 26: 2455-65.
22. Plotnick RE, Gardner RH, Hargrove WW, Prestegaard K, Perlmutter M. Lacunarity analysis: a general technique for the analysis of spatial patterns. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics 1996; 53: 5461-8.
23. Smith TG Jr, Lange GD, Marks WB. Fractal methods and results in cellular morphology - dimensions, lacunarity and multifractals. J Neurosci Methods 1996; 69: 123-36.
24. Goh V, Sanghera B, Wellsted DM, Sundin J, Halligan S. Assessment of the spatial pattern of colorectal tumour perfusion estimated at perfusion CT using twodimensional fractal analysis. Eur Radiol 2009; 19 : 1358-65.
25. Cao Y, Tsien CI, Sundgren PC, Nagesh V, Normolle D, Buchtel H, et al. Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for prediction of radiation-induced neurocognitive dysfunction. Clin Cancer Res 2009; 15: 1747-54. doi: 10.1158/1078-0432.CCR-08-1420
26. Almeida-Freitas DB, Pinho MC, Otaduy MC, Braga HF, Meira-Freitas D, da Costa Leite C. Assessment of irradiated brain metastases using dynamic contrast-enhanced magnetic resonance imaging. Neuroradiology 2014; 56: 437-43. doi: 10.1007/s00234-014-1344-0
27. Lazanyi KS, Abramyuk A, Wolf G, Tokalov S, Zöphel K, Appold S, et al. Usefulness of dynamic contrast enhanced computed tomography in patients with non-small-cell lung cancer scheduled for radiation therapy. Lung Cancer 2010; 70: 280-5. doi: 10.1016/j.lungcan.2010.03.004
28. Dugdale PE, Miles KA, Bunce I, Kelley BB, Leggett DA. CT measurement of perfusion and permeability within lymphoma masses and its ability to assess grade, activity, and chemotherapeutic response. J Comput Assist Tomogr 1999; 23: 540-7.
29. Ng QS, Goh V, Milner J, Padhani AR, Saunders MI, Hoskin PJ. Acute tumor vascular effects following fractionated radiotherapy in human lung cancer: in vivo whole tumor assessment using volumetric perfusion computed tomography. Int J Radiat Oncol Biol Phys 2007; 67: 417-24.
30. Surlan-Popovic K, Bisdas S, Rumboldt Z, Koh TS, Strojan P. Changes in perfusion CT of advanced squamous cell carcinoma of the head and neck treated during the course of concomitant chemoradiotherapy. AJNR Am J Neuroradiol 2010; 31: 570-5. doi: 10.3174/ajnr.A1859
31. Gupta VK, Jaskowiak NT, Beckett MA, Mauceri HJ, Grunstein J, Johnson RS, et al. Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance. Cancer J 2002; 8: 47-54.
32. Koutsimpelas D, Brieger J, Kim DW, Stenzel M, Hast J, Mann WJ. Proangiogenic effects of ionizing irradiation on squamous cell carcinoma of the hypopharynx. Auris Nasus Larynx 2008; 35: 369-75.
33. Yang Z, Tang LH, Klimstra DS. Effect of tumor heterogeneity on the assessment of Ki67 labeling index in well-differentiated neuroendocrine tumors metastatic to the liver: implications for prognostic stratification. Am J Surg Pathol 2011; 35: 853 -60. doi: 10.1097/PAS.0b013e31821a0696
34. Bisdas S, Rumboldt Z, Surlan-Popovic K, Baghi M, Koh TS, Vogl TJ, et al. Perfusion CT in squamous cell carcinoma of the upper aerodigestive tract: long-term predictive value of baseline perfusion CT measurements. AJNR Am J Neuroradiol 2010; 31: 576-81. doi: 10.3174/ajnr.A1852
35. Hermans R, Meijerink M, Van den Bogaert W, Rijnders A, Weltens C, Lambin P. Tumor perfusion rate determined noninvasively by dynamic computed tomography predicts outcome in head-and-neck cancer after radiotherapy. Int J Radiat Oncol Biol Phy 2003; 57: 1351-6.
36. Vaupel P. Tumor microenvironmental physiology and its implications for radiation oncology. Semin Radiat Oncol 2004; 14: 198-206.
37. Dankbaar JW, Hom J, Schneider T, Cheng SC, Lau BC, van der Schaaf I, et al. Dynamic perfusion CT assessment of the blood-brain barrier permeability: first pass versus delayed acquisition. AJNR Am J Neuroradiol 2008; 29: 1671-6. doi: 10.3174/ajnr.A1203
38. Bektas H,Wu TC, Kasam M, Harun N, Sitton CW, Grotta JC, et al. Increased blood-brain barrier permeability on perfusion CT might predict malignant middle cerebral artery infarction. Stroke 2010; 41: 2539-44. doi: 10.1161/STROKEAHA.110.591362
39. Bartoš M, Keunen O, Jirik R, Bjerkvig R, Taxt T. Perfusion analysis of dynamic contrast enhanced magnetic resonance images using a fully continuous tissue homogeneity model with mean transit time dispersion and frequency domain estimation of the signal delay. Biosignal 2010; 20: 269-74.
40. Riedel S. Pharmacokinetic modelling for dynamic contrast-enhanced MR renography. Bachelor thesis. Luebeck, Germany: University of Luebeck; 2012.
41. Fusco R, Sansone M, Maffei S, Raiano N, Petrillo A. Dynamic contrast-enhanced MRI in breast cancer: a comparison between distributed and compartmental tracer kinetic models. J Biomed Graphics Comput 2012; 2: 23-36.
42. Allain C, Cloitre M. Characterizing the lacunarity of random and deterministic fractal sets. Phys Rev A 1991; 44: 3552-8.