Psoriasin, A multifunctional player in different diseases

Current Protein and Peptide Science

Volumn 15, Issue 8, 2014, Pages 836-842

  Jia, Jinjing ^a   Duan, Qiqi ^a   Guo, Jiaqi ^a   Zheng, Yan ^a  

^a THE SECOND AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Cancer; Keratinocyte; Psoriasin; Psoriasis

Indexed keywords

BETA CATENIN; CD24 ANTIGEN; EPIDERMAL GROWTH FACTOR; GLYCOGEN SYNTHASE KINASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 17; INTERLEUKIN 22; MITOGEN ACTIVATED PROTEIN KINASE; PSORIASIN; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; PROTEIN S 100;

ANTIMICROBIAL ACTIVITY; ARTICLE; BASAL CELL CARCINOMA; BREAST ADENOCARCINOMA; CARCINOGENESIS; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CHROMOSOME REARRANGEMENT; EPIDERMIS; ESCHERICHIA COLI; HUMAN; INNATE IMMUNITY; LICHEN SCLEROSUS ET ATROPHICUS; METASTASIS; NEOPLASM; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; PSORIASIS; SIGNAL TRANSDUCTION; SKIN PROTECTION; SQUAMOUS CELL CARCINOMA; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT; CHEMISTRY; DISEASES; METABOLISM; PATHOLOGY; SKIN DISEASE;

DISEASE; EPIDERMIS; HUMANS; NEOPLASMS; S100 PROTEINS; SKIN DISEASES;

EID: 84919769960     PISSN: 13892037     EISSN: 18755550     Source Type: Journal    
DOI: 10.2174/138920371508141128152712     Document Type: Article

References (106)

1. Madsen, P.; Rasmussen, H. H.; Leffers, H.; Honore, B.; Dejgaard, K.; Olsen, E.; Kiil, J.; Walbum, E.; Andersen, A. H.; Basse, B.; Lauridsen, J. B.; Ratz, G. P.; Celis, A.; Vandekerckhove, J.; Celis, J. E. Molecular cloning, occurrence, and expression of a novel partially secreted protein "psoriasin" that is highly up-regulated in psoriatic skin. J. Invest. Dermatol., 1991, 97, 701-712.
2. Heizmann, C. W.; Fritz, G.; Schäfer, B. W. S100 proteins: structure, functions and pathology. Front. Biosci., 2002, 7, d1356-1368.
3. Marenholz, I.; Heizmann, C. W.; Fritz, G. S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature). Biochem. Biophys. Res. Commun., 2004, 322, 1111-1122.
4. Mischke, D.; Korge, B. P.; Marenholz, I.; Volz, A.; Ziegler, A. Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ("epidermal differentiation complex") on human chromosome 1q21. J. Invest. Dermatol., 1996, 106, 989-992.
5. Schäfer, B. W.; Heizmann, C. W. The S100 family of EF-hand calcium-binding proteins: functions and pathology. Trends. Biochem. Sci., 1996, 21, 134-140.
6. Schröder JM, Harder J. Innate antimicrobial peptides in the skin. Med. Sci. (Paris), 2006, 22, 153-157.
7. Eckert, R. L.; Broome, A. M.; Ruse, M.; Robinson, N.; Ryan, D.; Lee, K. S100 Proteins in the epidermis. J. Inves. Dermatol., 2004, 123, 23-33.
8. Donato, R. Intracellular and extracellular roles of S100 proteins. Microsc. Res. Tech., 2003, 60, 540-551.
9. Zimmer, D. B.; Wright, Sadosky, P.; Weber, D. J. Molecular mechanisms of S100-target protein interactions. Microsc. Res. Tech., 2003, 60, 552-559.
10. Donato, R. Functional roles of S100 proteins, caleium-binding proteins of the EF-hand type. Biochim. Biophys. Acta., 2009, 1450, 191-231.
11. Santamaria-Kisiel, L.; Rintala-Dempsey, A. C.; Shaw, G. S. Calcium-dependent and-independent interactions of the S100 protein family. Biochem. J., 2006, 396, 201-214.
12. Brodersen, D. E.; Etzerodt, M.; Madsen, P.; Celis, J. E.; Thøgersen, H. C.; Nyborg, J.; Kjeldgaard, M. EF-hands at atomic resolution: the structure of human psoriasin (S100A7) solved by MAD phasing. Structure, 1998, 6, 477-489.
13. Watson, P. H.; Leygue, E. R.; Murphy, L. C. Psoriasin (S100A7). Int. J. Biochem. Cell Biol., 1998, 30, 561-571.
14. Børglum, A. D.; Flint, T.; Madsen, P.; Celis, J. E.; Kruse, T. A. Refined mapping of the psoriasin gene S100A7 to chromosome 1cenq21. Hum. Genet., 1995, 96, 592-596.
15. Semprini, S.; Capon, F.; Bovolenta, S.; Bruscia, E.; Pizzuti, A.; Fabrizi, G.; Schietroma, C.; Zambruno, G.; Dallapiccola, B.; Novelli, G. Genomic structure, promoter characterisation and mutational analysis of the S100A7 gene: exclusion of a candidate for familial psoriasis susceptibility. Hum. Genet., 1999, 104, 130-134.
16. Randazzo, A.; Acklin, C.; Schäfer, B. W.; Heizmann, C. W.; Chazin, W. J. Structural insight into human Zn(2+)-bound S100A2 from NMR and homology modeling. Biochem. Biophys. Res. Commun., 2001, 288, 462-467.
17. Reithmayer, K.; Meyer, K. C.; Kleditzsch, P.; Tiede, S.; Uppalapati, S. K.; Gläser, R.; Harder, J.; Schröder, J. M.; Paus, R. Human hair follicle epithelium has an antimicrobial defence system that includes the inducible antimicrobial peptide psoriasin (S100A7) and RNase 7. Br. J. Dermatol., 2009, 161, 78-89.
18. Gläser, R.; Harder, J.; Lange, H.; Bartels, J.; Christophers, E.; Schröder, J. M. Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection. Nat. Immunol., 2005, 6, 57-64.
19. Lee, K. C.; Eckert, R. L. S100A7 (Psoriasin)-mechanism of antibacterial action in wounds. J. Invest. Dermatol., 2007, 127, 945-957.
20. Michalek, M.; Gelhaus, C.; Hecht, O.; Podschun, R.; Schröder, J. M.; Leippe, M.; Grotzinger, J. The human antimicrobial protein psoriasin acts by permeabilization of bacterial membranes. Dev. Comp. Immunol., 2009, 33, 740-746.
21. Wiesner, J.; Vilcinskas, A. Antimicrobial peptides: the ancient arm of the human immune system. Virulence, 2010, 1, 440-464.
22. Wolk, K.; Witte, E.; Wallace, E.; Docke, W. D.; Kunz, S.; Asadullah, K.; Volk, H. D.; Sterry, W.; Sabat, R. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur. J. Immunol.; 2006, 36, 1309-1323.
23. Abtin, A.; Eckhart, L.; Mildner, M.; Gruber, F.; Schröder, J. M.; Tschachler, E. Flagellin is the principal inducer of the antimicrobial peptide S100A7c (psoriasin) in human epidermal keratinocytes exposed to Escherichia coli. FASEB J., 2008, 22, 2168-2176.
24. Abtin, A.; Eckhart, L.; Mildner, M.; Gruber, F.; Schröder, J. M.; Tschachler, E. Flagellin is the principal inducer of the antimicrobial peptide S100A7c(psoriasin) in human epidermal keratinocytes exposed to Escherichia coli. FASEB J., 2008, 22, 2168-2176.
25. Brodersen, D. E.; Nyborg, J.; Kjeldgaard, M. Zinc-binding site of an S100 protein revealed. Two crystal structures of Ca2+-bound human psoriasin (S100A7) in the Zn2+-loadedand Zn2+-free states. Biochemistry, 1999, 38, 1695-1704.
26. Li, X.; de, Leeuw, E.; Lu, W. Total chemical synthesis of human psoriasin by native chemical ligation. Biochemistry, 2005, 44, 14688-14694.
27. Bevins, C. L. An important clue: fingerprints point to psoriasin in defense against E. coli. Nat. Immunol., 2005, 6, 12-13.
28. Vegfors, J.; Petersson, S.; Kovács, A.; Polyak, K.; Enerbäck, C. The expression of Psoriasin (S100A7) and CD24 is linked and related to the differentiation of mammary epithelial cells. PLoS One, 2012; 7, e53119.
29. Gläser, R.; Köten, B.; Wittersheim, M.; Harder, J. Psoriasin: key molecule of the cutaneous barrier?. J. Dtsch. Dermatol. Ges., 2011, 9, 897-902.
30. Sun, W.; Zheng, Y.; Lu, Z.; Cui, Y.; Tian, Q.; Xiao, S.; Liu, F.; Liu, J. Overexpression of S100A7 protects LPS-induced mitochondrial dysfunction and stimulates IL-6 and IL-8 in HaCaT cells. PLoS One, 2014, 9, e92927.
31. Hattori, F.; Kiatsurayanon, C.; Okumura, K.; Ogawa, H.; Ikeda, S.; Okamoto, K.; Niyonsaba, F. The antimicrobial protein S100A7/psoriasin enhances the expression of keratinocyte differentiation markers and strengthens the skin's tight junction barrier. Br. J. Dermatol., 2014. [Epub ahead of print].
32. Kvarnhammar, A. M.; Rydberg, C.; Järnkrants, M.; Eriksson, M.; Uddman, R.; Benson, M.; Cardell, L. O. Diminished levels of nasal S100A7 (psoriasin) in seasonal allergic rhinitis: an effect mediated by Th2 cytokines. Respir. Res., 2012, 13, 2.
33. Kim, K. H.; Cho, J. G.; Song, J. J.; Woo, J. S.; Lee, H. M.; Jung, H. H.; Hwang, S. J.; Chae, S. Psoriasin (S100A7), an antimicrobial peptide, is increased in human middle ear cholesteatoma. Acta. Otolaryngol., 2009, 129, 1067-1071.
34. Bryborn, M.; Adner, M.; Cardell, L. O. Psoriasin, one of several new proteins identified in nasal lavage fluid from allergic and nonallergic individuals using 2-dimensional gel electrophoresis and mass spectrometry. Respir. Res., 2005, 6, 118.
35. Meyer, J. E.; Harder, J.; Sipos, B.; Maune, S.; Klöppel, G.; Bartels, J.; Schröder, J. M.; Gläser, R. Psoriasin (S100A7) is a principal antimicrobial peptide of the human tongue. Mucosal Immunol., 2008, 1, 239-243.
36. Garreis, F.; Gottschalt, M.; Paulsen, F. P. Antimicrobial peptides as a major part of the innate immune defense at the ocular surface. Dev. Ophthalmol., 2010, 45, 16-22.
37. Garreis, F.; Gottschalt, M.; Schlorf, T.; Gläser, R.; Harder, J.; Worlitzsch, D.; Paulsen, F. P. Expression and regulation of antimicrobial peptide psoriasin (S100A7) at the ocular surface and in the lacrimal apparatus. Invest. Ophthalmol. Vis. Sci., 2011, 52, 4914-4922.
38. Yoshio, H.; Tollin, M.; Gudmundsson, G. H.; Lagercrantz, H.; Jornvall, H.; Marchini, G.; Agerberth, B. Antimicrobial polypeptides of human vernix caseosa and amniotic fluid: implications for newborn innate defense. Pediatr. Res., 2003, 53, 211-216.
39. Erhart, W.; Alkasi, Ö.; Brunke, G.; Wegener, F.; Maass, N.; Arnold, N.; Arlt, A.; Meinhold-Heerlein, I. Induction of human β-defensins and psoriasin in vulvovaginal human papillomavirusassociated lesions. J. Infect. Dis., 2011, 204, 391-399.
40. Porre, S.; Heinonen, S.; Mäntyjärvi, R.; Rytkönen-Nissinen, M.; Perola, O.; Rautiainen, J.; Virtanen, T. Psoriasin, a calcium-binding protein with chemotactic properties is present in the third trimester amniotic fluid. Mol. Hum. Reprod., 2005, 119, 87-92.
41. Mildner, M.; Stichenwirth, M.; Abtin, A.; Eckhart, L.; Sam, C.; Gläser, R.; Schröder, J. M.; Gmeiner, R.; Mlitz, V.; Pammer, J.; Geusau, A.; Tschachler, E. Psoriasin (S100A7) is a major Escherichia coli-cidal factor of the female genital tract. Mucosal. Immunol., 2010, 3, 602-609.
42. Tollin, M.; Jagerbrink, T.; Haraldsson, A.; Agerberth, B.; Jornvall, H. Proteome analysis of vernix caseosa. Pediatr. Res., 2006, 60, 430-434.
43. Teijeiro, J. M.; Marini, P. E. S100A7 is present in human sperm and a homologous pig sperm protein interacts with sperm-binding glycoprotein (SBG). Andrologia, 2012, 44 Suppl 1, 772-779.
44. Zhang, G. W.; Lai, S. J.; Yoshimura, Y.; Isobe, N. Messenger RNA expression and immunolocalization of psoriasin in the goat mammary gland and its milk concentration after an intramammary infusion of lipopolysaccharide. Vet. J., 2014. [Epub ahead of print].
45. Celis, J. E.; Cruger, D.; Kiil, J.; Dejgaard, K.; Lauridsen, J. B.; Ratz, G. P.; Basse, B.; Celis, A.; Rasmussen, H. H.; Bauw, G.; Vandekerckhoue, J. A two-dimensional gel protein database of noncultured total normal human epidermal keratinocytes: identification of proteins strongly up-regulated in psoriatic epidermis. Electrophoresis, 1990, 11, 242-254.
46. Kulski, J. K.; Lim, C. P.; Dunn, D. S.; Bellgard, M. Genomic and phylogenetic analysis of the S100A7 (Psoriasin) gene duplications within the region of the S100 gene cluster on human chromosome 1q21. J. Mol. Evol., 2003, 56, 97-406.
47. Jinquan, T.; Vorum, H.; Larsen, C. G.; Madsen, P.; Rasmussen, H. H.; Gesser, B.; Etzerodt, M.; Honoré, B.; Celis, J. E.; Thestrup-Pedersen, K. Psoriasin: A novel chemotactic protein. J. Invest. Dermatol., 1996, 107, 5-10.
48. Jeong, S. H.; Kim, H. J.; Jang, Y.; Ryu, W. I.; Lee, H.; Kim, J. H.; Bae, H. C.; Choi, J. E.; Kye, Y. C.; Son, S. W. Egr-1 is a key regulator of IL-17A-induced psoriasin upregulation in psoriasis. Exp. Dermatol., 2014. [Epub ahead of print].
49. Gambichler, T.; Skrygan, M.; Tomi, N. S.; Othlinghaus, N.; Brockmeyer, N. H.; Altmeyer, P.; Kreuter, A. Differential mRNA expression of antimicrobial peptides and proteins in atopic dermatitis as compared to psoriasis vulgaris and healthy skin. Int. Arch. Allergy. Immunol., 2008, 147, 17-24.
50. Harder, J.; Dressel, S.; Wittersheim, M.; Cordes, J.; Meyer-Hoffert, U.; Mrowietz, U.; Folster-Holst, R.; Proksch, E.; Schröder, J. M.; Schwarz, T.; Gläser, R. Enhanced expression and secretion of antimicrobial peptides in atopic dermatitis and after superficial skin injury. J. Invest. Dermatol., 2010, 130, 1355-1364.
51. Algermissen, B.; Sitzmann, J.; LeMotte, P.; Czarnetzki, B. Differential expression of CRABP II, psoriasin and cytokeratin 1 mRNA in human skin diseases. Arch. Dermatol. Res.; 1996, 288, 426-430.
52. Harder, J.; Schröder, J. M. Psoriatic scales: a promising source for the isolation of human skin-derived antimicrobial proteins. J. Leukoc. Biol., 2005, 77, 476-486.
53. Gambichler, T.; Skrygan, M.; Tigges, C.; Kobus, S.; Gläser, R.; Kreuter, A. Significant upregulation of antimicrobial peptides and proteins in lichen sclerosus. Br. J. Dermatol., 2009, 161, 1136-1142.
54. Schlapbach, C.; Yawalkar, N.; Hunger, R. E. Human beta-defensin-2 and psoriasin are overexpressed in lesions of acne inversa. J. Am. Acad. Dermatol., 2009, 61, 58-65.
55. Ganceviciene, R.; Fimmel, S.; Glass, E.; Zouboulis, C. C. Psoriasin and follicular hyperkeratinization in acne comedones. Dermatology, 2006, 213, 270-272.
56. Xu L, Zeng WH, Zheng Y. Expression of psoriasin in mycosis fungoides and its significance. Nan Fang Yi Ke Da Xue Xue Bao, 2011, 31, 1907-1909. (In Chinese).
57. Gläser, R.; Meyer-Hoffert, U.; Harder, J.; Cordes, J.; Wittersheim, M.; Kobliakova, J.; Folster-Holst, R.; Proksch, E.; Schröder, J. M.; Schwarz, T. The antimicrobial protein psoriasin (S100A7) is upregulated in atopic dermatitis and after experimental skin barrier disruption. J. Invest. Dermatol., 2009, 129, 641-649.
58. Dressel, S.; Harder, J.; Cordes, J.; Wittersheim, M.; Meyer-Hoffert, U.; Sunderkotter, C.; Gläser, R. Differential expression of antimicrobial peptides in margins of chronic wounds. Exp. Dermatol., 2010, 19, 628-632.
59. Broome, A. M.; Ryan, D.; Eckert, R. L. S100 protein subcellular localization during epidermal differentiation and psoriasis. J. Histochem. Cytochem., 2003, 51, 675-685.
60. Ruse, M.; Broome, A. M.; Eckert, R. L. S100A7(psoriasin) interacts with epidermal fatty acid binding protein and localizes in focal adhesion-like structures in cultured keratinocytes. J. Invest. Dermatol., 2003, 121, 132-141.
61. Hagens, G.; Masouye, I.; Augsburger, E.; Hotz, R.; Saurat, J. H.; Siegenthaler, G. Calcium-binding protein S100A7 and epidermaltype fatty acid-binding protein are associated in the cytosol of human keratinocytes. Biochem. J., 1999, 339, 419-427.
62. Hagens, G.; Roulin, K.; Hotz, R.; Saurat, J. H.; Hellman, U.; Siegenthaler, G. Probable interaction between S100A7 and EFABP in the cytosol of human keratinocytes from psoriatic scales. Mol. Cell Biochem., 1999, 192, 123-128.
63. Liang, S. C.; Tan, X. Y.; Luxenberg, D. P.; Karim, R.; Dunussi-Joannopoulos, K.; Collins, M.; Fouser, L. A. Interleukin(IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J. Exp. Med., 2006, 203, 2271-2279.
64. Hegyi, Z.; Zwicker, S.; Bureik, D.; Peric, M.; Koglin, S.; Batycka-Baran, A.; Prinz, J. C.; Ruzicka, T.; Schauber, J.; Wolf, R. Vitamin D analog calcipotriol suppresses the Th17 cytokine-induced proinflammatory S100 "alarmins" psoriasin (S100A7) and koebnerisin (S100A15) in psoriasis. J. Invest. Dermatol., 2012, 132, 1416-1424.
65. Li, T.; Cowley, EA. Reduced expression of psoriasin in human airway cystic fibrosis epithelia. Respir. Physiol. Neurobiol., 2012, 183, 177-185.
66. Tavakkol, A.; Zouboulis, C. C.; Duell, E. A.; Voorhees, J. J. A retinoic acid-inducible skin-specific gene (RIS-1/psoriasin): Molecular cloning and analysis of gene expression in human skin in vivo and cultured skin cells in vitro. Mol. Biol. Rep., 1994, 20, 75-83.
67. Hoffmann, H. J.; Olsen, E.; Etzerodt, M.; Madsen, P.; Thogersen, H. C.; Kruse, T.; Celis, J. E. Psoriasin binds calcium and is upregulated by calcium to levels that resemble those observed in normal skin. J. Invest. Dermatol., 1994, 103, 370-375.
68. Zouboulis, C. C.; Voorhees, J. J.; Orfanos, C. E.; Tavakkol, A. Topical all-trans retinoic acid (RA) induces an early, coordinated increase in RA-inducible skin-specific gene/psoriasin and cellular RA-binding protein II mRNA levels which precedes skin erythema. Arch. Dermatol. Res., 1996, 288, 664.
69. Di, Nuzzo, S.; Sylva-Steenland, R. M.; Koomen, C. W.; de, Rie, M. A.; Das, P. K.; Bos, J. D.; Teunissen, M. B. Exposure to UVB induces accumulation of LFA-1+ T cells and enhanced expression of the chemokine psoriasin in normal human skin. Photochem. Photobiol., 2000, 72, 374-382.
70. Schröder, J. M.; Schwarz, A.; Schwarz, T. UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo. J. Allergy Clin. Immunol., 2009, 123, 1117-1123.
71. Zheng, Y.; Niyonsaba, F.; Ushio, H.; Ikeda, S.; Nagaoka, I.; Okumura, K.; Ogawa, H. Microbicidal protein psoriasin is a multifunctional modulator of neutrophil activation. Immunology, 2008, 124, 357-367.
72. Celis, J. E.; Rasmussen, H. H.; Vorum, H.; Madsen, P.; Honore, B.; Wolf, H.; Orntoft, T. F. Bladder squamous cell carcinomas express psoriasin and externalize it to the urine. J. Urol., 1996, 155, 2105-2112.
73. Alowami. S.; Qing, G.; Emberley, E.; Snell, L.; Watson, P. H. Psoriasin (S100A7) expression is altered during skin tumorigenesis. BMC Dermatol,. 2003, 3, 1.
74. Ostergaard, M.; Rasmussen, H. H.; Nielsen, H. V.; Vorum, H.; Orntoft, T. F.; Wolf, H.; Celis, J. E. Proteome profiling of bladder squamous cell carcinomas: identification of markers that define their degree of differentiation. Cancer Res., 1997, 57, 4111-4117.
75. Ostergaard, M.; Wolf, H.; Orntoft, T. F.; Celis, J. E. Psoriasin (S100A7): a putative urinary marker for the follow-up of patients with bladder squamous cell carcinomas. Electrophoresis, 1999, 20, 349-354.
76. Moog-Lutz, C.; Bouillet, P.; Regnier, C. H.; Tomasetto, C.; Mattei, M. G.; Chenard, M. P.; Anglard, P.; Rio, M. C. Basset, P. Comparative expression of the psoriasin (S100A7) and S100C genes in breast carcinoma and co-localization to human chromosome 1q21-q22. Int. J. Cancer., 1995, 63, 297-303.
77. Leygue, E.; Snell, L.; Hiller, T.; Dotzlaw, H.; Hole, K.; Murphy, L. C.; Watson, P. H. Differential expression of psoriasin messenger RNA between in situ and invasive human breast carcinoma. Cancer Res., 1996, 56, 4606-4609.
78. Wolf, R.; Ruzicka, T.; Yuspa, S. H. Novel S100A7 (psoriasin)/S100A15 (koebnerisin) subfamily: highly homologous but distinct in regulation and function. Amino Acids, 2011, 41, 789-796.
79. Barbieri, M. R.; Andrade, C. D.; Silva, W. A. Jr.; Marques, A. A.; Leopoldino, A. M.; Montes, M. B.; Dias-Baruffi, M.; Soares, I. C.; Wakamatsu, A.; Alves, V. A.; Laure, H. J.; Zago, M. A.; Greene, L. J. Expression of human protein S100A7 (psoriasin), preparation of antibody and application to human larynx squamous cell carcinoma. BMC Res. Notes., 2011, 4, 494.
80. Webb, M.; Emberley, E. D.; Lizardo, M.; Alowami, S.; Qing, G.; Alfia'ar, A.; Snell-Curtis, L. J.; Niu, Y.; Civetta, A.; Myal, Y.; Shiu, R.; Murphy, L. C.; Watson, P. H. Expression analysis of the mouse S100A7/psoriasin gene in skin inflammation and mammary tumorigenesis. BMC Cancer, 2005, 5, 17.
81. Al-Haddad, S.; Zhang, Z.; Leygue, E.; Snell, L.; Huang, A.; Niu, Y.; Hiller-Hitchcock, T.; Hole, K.; Murphy, L. C.; Watson, P. H. Psoriasin (S100A7) expression and invasive breast cancer. Am. J. Pathol., 1999, 155, 2057-2066.
82. Emberley, E. D.; Murphy, L. C.; Watson, P. H. S100A7 and the progression of breast cancer. Breast Cancer Res., 2004, 6, 153-159.
83. Wolf, R.; Voscopoulos, C.; Winston, J.; Dharamsi, A.; Goldsmith, P.; Gunsior, M.; Vonderhaar, B. K.; Olson, M.; Watson, P. H.; Yuspa, S. H. Highly homologous hS100A15 and hS100A7 proteins are distinctly expressed in normal breast tissue and breast cancer. Cancer Lett., 2009, 277, 101-7.
84. Kaur, J.; Matta, A.; Kak, I.; Srivastava, G.; Assi, J.; Leong, I.; Witterick, I.; Colgan, T. J.; Macmillan, C.; Siu, K. W.; Walfish, P. G.; Ralhan, R. S100A7 overexpression is a predictive marker for high risk of malignant transformation in oral dysplasia. Int. J. Cancer., 2014, 134, 1379-1388.
85. Hu, M.; Ye, L.; Ruge, F.; Zhi, X.; Zhang, L.; Jiang, W. G. The clinical significance of Psoriasinfor non-small cell lung cancer patients and its biological impact on lung cancer cell functions. BMC Cancer, 2012, 12, 588.
86. Leon, R.; Murray, J. I.; Cragg, G.; Farnell, B.; West, N. R.; Pace, T. C.; Watson, P. H.; Bohne, C.; Boulanger, M. J.; Hof, F. Identification and characterization of binding sites on S100A7, a participant in cancer and inflammation pathways. Biochemistry, 2009, 48, 10591-10600.
87. Moubayed, N.; Weichenthal, M.; Harder, J.; Wandel, E.; Sticherling, M.; Gläser, R. Psoriasin (S100A7) is significantly upregulated in human epithelial skin tumours. J. Cancer Res. Clin. Oncol., 2007, 133, 253-261.
88. Paruchuri, V.; Prasad, A.; McHugh, K.; Bhat, H. K.; Polyak, K.; Ganju, R. K. S100A7-downregulation inhibits epidermal growth factor-induced signaling in breast cancer cells and blocks osteoclastformation. PLoS One, 2008, 3, e1741.
89. Deol, Y. S.; Nasser, M. W.; Yu, L.; Zou, X.; Ganju, R. K. Tumorsuppressive effects of psoriasin (S100A7) are mediated through the beta-catenin/T cell factor 4 protein pathway in estrogen receptorpositive breast cancer cells. J. Biol. Chem., 2011, 286, 44845-44854.
90. Nasser, M. W.; Qamri, Z.; Deol, Y. S.; Ravi, J.; Powell, C. A.; Trikha, P.; Schwendener, R. A.; Bai, X. F.; Shilo, K.; Zou, X.; Leone, G.; Wolf, R.; Yuspa, S. H.; Ganju, R. K. S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways. Cancer Res., 2012, 72, 604-615.
91. Andresen, E.; Lange, C.; Strodthoff, D.; Goldmann, T.; Fischer, N.; Sahly, H.; Branscheid, D.; Heine, H. S100A7/psoriasin expression in the human lung: unchanged in patients with COPD, but upregulated upon positive S. aureus detection. BMC Pulm. Med., 2011, 11, 10.
92. Sneh, A.; Deol, Y. S.; Ganju, A.; Shilo, K.; Rosol, T. J.; Nasser, M. W.; Ganju, R. K. Differential role of psoriasin (S100A7) in estrogen receptor β positive and negative breast cancer cells occur through actin remodeling. Breast Cancer Res. Treat., 2013, 138, 727-739.
93. Emberley, E. D.; Alowami, S.; Snell, L.; Murphy, L. C.; Watson, P. H. S100A7 (psoriasin) expression is associated with aggressive features and alteration of Jab1 in ductal carcinoma in situ of the breast. Breast Cancer Res., 2004, 6, R308-315.
94. Mandal, S.; Curtis, L.; Pind, M.; Murphy, L. C.; Watson, P. H. S100A7 (psoriasin) influences immune response genes in human breast cancer. Exp. Cell Res., 2007, 313, 3016-3025.
95. Emberley, E. D.; Niu, Y.; Leygue, E.; Tomes, L.; Gietz, R. D.; Murphy, L. C.; Watson, P. H. Psoriasin interacts with Jab1 and influences breast cancer progression. Cancer Res., 2003, 63, 1954-1961.
96. Petersson, S.; Shubbar, E.; Yhr, M.; Kovacs, A.; Enerbäck, C. Loss of ICAM-1 signaling induces psoriasin (S100A7) and MUC1 in mammary epithelial cells. Breast Cancer Res. Treat., 2011, 125, 13-25.
97. Emberley, E. D.; Niu, Y.; Curtis, L.; Troup, S.; Mandal, S. K.; Myers, J. N.; Gibson, S. B.; Murphy, L. C.; Watson, P. H.; The S100A7-c-Jun activation domain binding protein 1 pathway enhances prosurvival pathways in breast cancer. Cancer Res., 2005, 65, 5696-5702.
98. Petersson, S.; Bylander, A.; Yhr, M.; Enerbäck, C. S100A7 (Psoriasin), highly expressed in ductal carcinoma in situ (DCIS), is regulated by IFN-gamma in mammary epithelial cells. BMC Cancer, 2007, 7, 205.
99. Shubbar, E.; Vegfors, J.; Carlström, M.; Petersson, S.; Enerbäck, C. Psoriasin (S100A7) increases the expression of ROS and VEGF and acts through RAGE to promote endothelial cell proliferation. Breast Cancer Res. Treat., 2012, 134, 71-80.
100. Krop, I.; März, A.; Carlsson, H.; Li, X.; Bloushtain-Qimron, N.; Hu, M.; Gelman, R.; Sabel, M. S.; Schnitt, S.; Ramaswamy, S.; Kleer, C. G.; Enerbäck, C.; Polyak, K. A putative role for psoriasin in breast tumor progression. Cancer Res., 2005, 65, 11326-11334.
101. Hattinger, E.; Zwicker, S.; Ruzicka, T.; Yuspa, S. H.; Wolf, R. Opposing functions of psoriasin (S100A7) and koebnerisin (S100A15) in epithelial carcinogenesis. Curr. Opin. Pharmacol., 2013, 13, 588-594.
102. West, N. R.; Watson, P. H. S100A7 (psoriasin) is induced by the proinflammatory cytokines oncostatin-M and interleukin-6 in human breast cancer. Oncogene, 2010, 29, 2083-2092.
103. Ye, L.; Sun, P. H.; Martin, T. A.; Sanders, A. J.; Mason, M. D.; Jiang, W. G. Psoriasin (S100A7) is a positive regulator of survival and invasion of prostate cancer cells. Urol. Oncol., 2013, 31, 1576-1583.
104. Kataoka, K.; Ono, T.; Murata, H.; Morishita, M.; Yamamoto, K. I.; Sakaguchi, M.; Huh, N. H. S100A7 promotes the migration and invasion of osteosarcoma cells via the receptor for advanced glycation end products. Oncol. Lett., 2012, 3, 1149-1153.
105. Kesting, M. R.; Sudhoff, H.; Hasler, R. J.; Nieberler, M.; Pautke, C.; Wolff, K. D.; Wagenpfeil, S.; Al-Benna, S.; Jacobsen, F.; Steinstraesser, L. Psoriasin (S100A7) up-regulation in oral squamous cell carcinoma and its relation to clinicopathologic features. Oral Oncol., 2009, 45, 731-736.
106. Zhou, G.; Xie, T. X.; Zhao, M.; Jasser, S. A.; Younes, M. N.; Sano, D.; Lin, J.; Kupferman, M. E.; Santillan, A. A.; Patel, V.; Gutkind, J. S.; Ei-Naggar, A. K.; Emberley, E. D.; Watson, P. H.; Matsuzawa, S. I.; Reed, J. C.; Myers, J. N. Reciprocal negative regulation between S100A7/psoriasin and beta-catenin signaling plays an important role in tumor progression of squamous cell carcinoma of oral cavity. Oncogene, 2008, 27, 3527-3538.