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Volumn 124, Issue 3, 2008, Pages 357-367

Microbicidal protein psoriasin is a multifunctional modulator of neutrophil activation

Author keywords

Cytokine chemokine; Human defensin; Neutrophil; Psoriasin; Reactive oxygen species

Indexed keywords

ALPHA DEFENSIN; CHEMOKINE; CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PSORIASIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STRESS ACTIVATED PROTEIN KINASE;

EID: 44849110924     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2007.02782.x     Document Type: Article
Times cited : (85)

References (58)
  • 1
    • 33847011002 scopus 로고    scopus 로고
    • Human defensins and cathelicidins in the skin: Beyond direct antimicrobial properties
    • Niyonsaba F, Nagaoka I, Ogawa H. Human defensins and cathelicidins in the skin: beyond direct antimicrobial properties. Crit Rev Immunol 2006 26: 545 76.
    • (2006) Crit Rev Immunol , vol.26 , pp. 545-76
    • Niyonsaba, F.1    Nagaoka, I.2    Ogawa, H.3
  • 2
    • 0032983595 scopus 로고    scopus 로고
    • Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type
    • Donato R. Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type. Biochim Biophys Acta 1999 1450: 191 231.
    • (1999) Biochim Biophys Acta , vol.1450 , pp. 191-231
    • Donato, R.1
  • 4
    • 0026042087 scopus 로고
    • Molecular cloning, occurrence, and expression of a novel partially secreted protein "psoriasin" that is highly up-regulated in psoriatic skin
    • Madsen P, Rasmussen HH, Leffers H et al. Molecular cloning, occurrence, and expression of a novel partially secreted protein "psoriasin" that is highly up-regulated in psoriatic skin. J Invest Dermatol 1991 97: 701 12.
    • (1991) J Invest Dermatol , vol.97 , pp. 701-12
    • Madsen, P.1    Rasmussen, H.H.2    Leffers, H.3
  • 5
    • 0029787271 scopus 로고    scopus 로고
    • Differential expression of CRABP II, psoriasin and cytokeratin 1 mRNA in human skin diseases
    • Algermissen B, Sitzmann J, LeMotte P, Czarnetzki B. Differential expression of CRABP II, psoriasin and cytokeratin 1 mRNA in human skin diseases. Arch Dermatol Res 1996 288: 426 30.
    • (1996) Arch Dermatol Res , vol.288 , pp. 426-30
    • Algermissen, B.1    Sitzmann, J.2    Lemotte, P.3    Czarnetzki, B.4
  • 6
    • 0028802976 scopus 로고
    • Comparative expression of the psoriasin (S100A7) and S100C genes in breast carcinoma and co-localization to human chromosome 1q21-q22
    • Moog-Lutz C, Bouillet P, Regnier CH et al. Comparative expression of the psoriasin (S100A7) and S100C genes in breast carcinoma and co-localization to human chromosome 1q21-q22. Int J Cancer 1995 63: 297 303.
    • (1995) Int J Cancer , vol.63 , pp. 297-303
    • Moog-Lutz, C.1    Bouillet, P.2    Regnier, C.H.3
  • 9
    • 0032979025 scopus 로고    scopus 로고
    • Psoriasin (S100A7): A putative urinary marker for the follow-up of patients with bladder squamous cell carcinomas
    • Ostergaard M, Wolf H, Orntoft TF, Celis JE. Psoriasin (S100A7): a putative urinary marker for the follow-up of patients with bladder squamous cell carcinomas. Electrophoresis 1999 20: 349 54.
    • (1999) Electrophoresis , vol.20 , pp. 349-54
    • Ostergaard, M.1    Wolf, H.2    Orntoft, T.F.3    Celis, J.E.4
  • 12
    • 33947241444 scopus 로고    scopus 로고
    • S100A7 (psoriasin) - Mechanism of antibacterial action in wounds
    • Lee KC, Eckert RL. S100A7 (psoriasin) - mechanism of antibacterial action in wounds. J Invest Dermatol 2007 127: 945 57.
    • (2007) J Invest Dermatol , vol.127 , pp. 945-57
    • Lee, K.C.1    Eckert, R.L.2
  • 13
    • 2442443134 scopus 로고    scopus 로고
    • Phagocyte-specific calcium-binding S100 proteins as clinical laboratory markers of inflammation
    • Foell D, Frosch M, Sorg C, Roth J. Phagocyte-specific calcium-binding S100 proteins as clinical laboratory markers of inflammation. Clin Chim Acta 2004 344: 37 51.
    • (2004) Clin Chim Acta , vol.344 , pp. 37-51
    • Foell, D.1    Frosch, M.2    Sorg, C.3    Roth, J.4
  • 15
    • 0030049050 scopus 로고    scopus 로고
    • Induction of adherence and degranulation of polymorphonuclear leukocytes: A new expression of the invasive phenotype of Shigella flexneri
    • Renesto P, Mounier J, Sansonetti PJ. Induction of adherence and degranulation of polymorphonuclear leukocytes: a new expression of the invasive phenotype of Shigella flexneri. Infect Immun 1996 64: 719 23.
    • (1996) Infect Immun , vol.64 , pp. 719-23
    • Renesto, P.1    Mounier, J.2    Sansonetti, P.J.3
  • 16
    • 0020625894 scopus 로고
    • Flow cytometric studies of oxidative product formation by neutrophils: A graded response to membrane stimulation
    • Bass DA, Parce JW, Dechatelet LR, Szejda P, Seeds MC, Thomas M. Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation. J Immunol 1983 130: 1910 7.
    • (1983) J Immunol , vol.130 , pp. 1910-7
    • Bass, D.A.1    Parce, J.W.2    Dechatelet, L.R.3    Szejda, P.4    Seeds, M.C.5    Thomas, M.6
  • 17
    • 0026554428 scopus 로고
    • Evaluation of the probe 2′,7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress
    • LeBel CP, Ischiropoulos H, Bondy SC. Evaluation of the probe 2′,7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem Res Toxicol 1992 5: 227 31.
    • (1992) Chem Res Toxicol , vol.5 , pp. 227-31
    • Lebel, C.P.1    Ischiropoulos, H.2    Bondy, S.C.3
  • 18
    • 33847040438 scopus 로고    scopus 로고
    • Antimicrobial peptides human β-defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines
    • Niyonsaba F, Ushio H, Nakano N et al. Antimicrobial peptides human β-defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines. J Invest Dermatol 2007 127: 594 604.
    • (2007) J Invest Dermatol , vol.127 , pp. 594-604
    • Niyonsaba, F.1    Ushio, H.2    Nakano, N.3
  • 20
    • 33751532376 scopus 로고    scopus 로고
    • The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system
    • Barlow PG, Li Y, Wilkinson TS et al. The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system. J Leukoc Biol 2006 80: 509 20.
    • (2006) J Leukoc Biol , vol.80 , pp. 509-20
    • Barlow, P.G.1    Li, Y.2    Wilkinson, T.S.3
  • 21
    • 22544457464 scopus 로고    scopus 로고
    • The human β-defensins (-1, -2, -3, -4) and cathelicidin LL-37 induce IL-18 secretion through p38 and ERK MAPK activation in primary human keratinocytes
    • Niyonsaba F, Ushio H, Nagaoka I, Okumura K, Ogawa H. The human β-defensins (-1, -2, -3, -4) and cathelicidin LL-37 induce IL-18 secretion through p38 and ERK MAPK activation in primary human keratinocytes. J Immunol 2005 175: 1776 84.
    • (2005) J Immunol , vol.175 , pp. 1776-84
    • Niyonsaba, F.1    Ushio, H.2    Nagaoka, I.3    Okumura, K.4    Ogawa, H.5
  • 22
    • 33744512882 scopus 로고    scopus 로고
    • Human cathelicidin LL-37 increases vascular permeability in the skin via mast cell activation, and phosphorylates MAP kinases p38 and ERK in mast cells
    • Chen X, Niyonsaba F, Ushio H, Nagaoka I, Ikeda S, Okumura K, Ogawa H. Human cathelicidin LL-37 increases vascular permeability in the skin via mast cell activation, and phosphorylates MAP kinases p38 and ERK in mast cells. J Dermatol Sci 2006 43: 63 6.
    • (2006) J Dermatol Sci , vol.43 , pp. 63-6
    • Chen, X.1    Niyonsaba, F.2    Ushio, H.3    Nagaoka, I.4    Ikeda, S.5    Okumura, K.6    Ogawa, H.7
  • 23
    • 33947728599 scopus 로고    scopus 로고
    • Antimicrobial peptides human β-defensin (hBD)-3 and hBD-4 activate mast cells and increase skin vascular permeability
    • Chen X, Niyonsaba F, Ushio H et al. Antimicrobial peptides human β-defensin (hBD)-3 and hBD-4 activate mast cells and increase skin vascular permeability. Eur J Immunol 2007 37: 434 44.
    • (2007) Eur J Immunol , vol.37 , pp. 434-44
    • Chen, X.1    Niyonsaba, F.2    Ushio, H.3
  • 24
    • 1542724426 scopus 로고    scopus 로고
    • The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes
    • Bowdish DM, Davidson DJ, Speert DP, Hancock RE. The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes. J Immunol 2004 172: 3758 65.
    • (2004) J Immunol , vol.172 , pp. 3758-65
    • Bowdish, D.M.1    Davidson, D.J.2    Speert, D.P.3    Hancock, R.E.4
  • 25
    • 0031423791 scopus 로고    scopus 로고
    • Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: Implications for intracellular measurement of reactive nitrogen and oxygen species
    • Crow JP. Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: implications for intracellular measurement of reactive nitrogen and oxygen species. Nitric Oxide 1997 1: 145 57.
    • (1997) Nitric Oxide , vol.1 , pp. 145-57
    • Crow, J.P.1
  • 26
    • 0025218905 scopus 로고
    • Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2′,7′-dichlorofluorescin
    • Rothe G, Valet G. Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2′,7′-dichlorofluorescin. J Leukoc Biol 1990 47: 440 8.
    • (1990) J Leukoc Biol , vol.47 , pp. 440-8
    • Rothe, G.1    Valet, G.2
  • 27
    • 0023894234 scopus 로고
    • The effect of the NADPH oxidase inhibitor diphenyleneiodonium on aerobic and anaerobic microbicidal activities of human neutrophils
    • Ellis JA, Mayer SJ, Jones OT. The effect of the NADPH oxidase inhibitor diphenyleneiodonium on aerobic and anaerobic microbicidal activities of human neutrophils. Biochem J 1988 251: 887 97.
    • (1988) Biochem J , vol.251 , pp. 887-97
    • Ellis, J.A.1    Mayer, S.J.2    Jones, O.T.3
  • 28
    • 0032545445 scopus 로고    scopus 로고
    • Diphenyleneiodonium, an NAD(P)H oxidase inhibitor, also potently inhibits mitochondrial reactive oxygen species production
    • Li Y, Trush MA. Diphenyleneiodonium, an NAD(P)H oxidase inhibitor, also potently inhibits mitochondrial reactive oxygen species production. Biochem Biophys Res Commun 1998 253: 295 9.
    • (1998) Biochem Biophys Res Commun , vol.253 , pp. 295-9
    • Li, Y.1    Trush, M.A.2
  • 29
    • 0025074343 scopus 로고
    • Expression of xanthine oxidase activity by murine leukocytes
    • Grum CM, Gross TJ, Mody CH, Sitrin RG. Expression of xanthine oxidase activity by murine leukocytes. J Lab Clin Med 1990 116: 211 8.
    • (1990) J Lab Clin Med , vol.116 , pp. 211-8
    • Grum, C.M.1    Gross, T.J.2    Mody, C.H.3    Sitrin, R.G.4
  • 30
    • 0037033433 scopus 로고    scopus 로고
    • Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: Selective regulation of mitogen-activated protein kinase activation and Fas ligand expression
    • Devadas S, Zaritskaya L, Rhee SG, Oberley L, Williams MS. Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: selective regulation of mitogen-activated protein kinase activation and Fas ligand expression. J Exp Med 2002 195: 59 70.
    • (2002) J Exp Med , vol.195 , pp. 59-70
    • Devadas, S.1    Zaritskaya, L.2    Rhee, S.G.3    Oberley, L.4    Williams, M.S.5
  • 31
    • 0030996649 scopus 로고    scopus 로고
    • Comparative studies on the extracellular release and biological activity of guinea pig neutrophil cationic antibacterial polypeptide of 11 kDa (CAP11) and defensins
    • Yomogida S, Nagaoka I, Yamashita T. Comparative studies on the extracellular release and biological activity of guinea pig neutrophil cationic antibacterial polypeptide of 11 kDa (CAP11) and defensins. Comp Biochem Physiol B Biochem Mol Biol 1997 116: 99 107.
    • (1997) Comp Biochem Physiol B Biochem Mol Biol , vol.116 , pp. 99-107
    • Yomogida, S.1    Nagaoka, I.2    Yamashita, T.3
  • 34
    • 0024511945 scopus 로고
    • Determination of the disulfide array in the human defensin HNP-2: A covalently cyclized peptide
    • Selsted ME, Harwig SS. Determination of the disulfide array in the human defensin HNP-2: a covalently cyclized peptide. J Biol Chem 1989 264: 4003 7.
    • (1989) J Biol Chem , vol.264 , pp. 4003-7
    • Selsted, M.E.1    Harwig, S.S.2
  • 35
    • 0033950099 scopus 로고    scopus 로고
    • Role of neutrophils in induction of acute inflammation in T-cell-mediated immune dermatosis, psoriasis: A neutrophil-associated inflammation-boosting loop
    • Terui T, Ozawa M, Tagami H. Role of neutrophils in induction of acute inflammation in T-cell-mediated immune dermatosis, psoriasis: a neutrophil-associated inflammation-boosting loop. Exp Dermatol 2000 9: 1 10.
    • (2000) Exp Dermatol , vol.9 , pp. 1-10
    • Terui, T.1    Ozawa, M.2    Tagami, H.3
  • 36
    • 0033523664 scopus 로고    scopus 로고
    • Cytokine-activated endothelial cells delay neutrophil apoptosis in vitro and in vivo: A role for granulocytes/macrophage colony-stimulating factor
    • Coxon A, Tang T, Mayadas N. Cytokine-activated endothelial cells delay neutrophil apoptosis in vitro and in vivo: a role for granulocytes/macrophage colony-stimulating factor. J Exp Med 1999 190: 923 34.
    • (1999) J Exp Med , vol.190 , pp. 923-34
    • Coxon, A.1    Tang, T.2    Mayadas, N.3
  • 37
    • 0026563730 scopus 로고
    • Poly's lament: The neglected role of the polymorphonuclear neutrophil in the afferent limb of the immune response
    • Lloyd AR, Oppenheim JJ. Poly's lament: the neglected role of the polymorphonuclear neutrophil in the afferent limb of the immune response. Immunol Today 1992 13: 169 72.
    • (1992) Immunol Today , vol.13 , pp. 169-72
    • Lloyd, A.R.1    Oppenheim, J.J.2
  • 38
    • 0028894398 scopus 로고
    • The production of cytokines by polymorphonuclear neutrophils
    • Cassatella MA. The production of cytokines by polymorphonuclear neutrophils. Immunol Today 1995 16: 21 6.
    • (1995) Immunol Today , vol.16 , pp. 21-6
    • Cassatella, M.A.1
  • 39
    • 0028287092 scopus 로고
    • Interleukin 10 (IL-10) upregulates IL-1 receptor antagonist production from lipopolysaccharide-stimulated human polymorphonuclear leukocytes by delaying mRNA degradation
    • Cassatella MA, Meda L, Gasperini S, Calzetti F, Bonora S. Interleukin 10 (IL-10) upregulates IL-1 receptor antagonist production from lipopolysaccharide-stimulated human polymorphonuclear leukocytes by delaying mRNA degradation. J Exp Med 1994 179: 1695 9.
    • (1994) J Exp Med , vol.179 , pp. 1695-9
    • Cassatella, M.A.1    Meda, L.2    Gasperini, S.3    Calzetti, F.4    Bonora, S.5
  • 40
    • 0033564304 scopus 로고    scopus 로고
    • Human polymorphonuclear leukocytes produce IL-12, TNF-α, and the chemokines macrophage-inflammatory protein-1α and -1β in response to Toxoplasma gondii antigens
    • Bliss SK, Marshall AJ, Zhang Y, Denkers EY. Human polymorphonuclear leukocytes produce IL-12, TNF-α, and the chemokines macrophage- inflammatory protein-1α and -1β in response to Toxoplasma gondii antigens. J Immunol 1999 162: 7369 75.
    • (1999) J Immunol , vol.162 , pp. 7369-75
    • Bliss, S.K.1    Marshall, A.J.2    Zhang, Y.3    Denkers, E.Y.4
  • 41
    • 0037222420 scopus 로고    scopus 로고
    • Production of macrophage inflammatory protein 3α (MIP-3α) (CCL20) and MIP-3β (CCL19) by human peripheral blood neutrophils in response to microbial pathogens
    • Akahoshi T, Sasahara T, Namai R, Matsui T, Watabe H, Kitasato H, Inoue M, Kondo H. Production of macrophage inflammatory protein 3α (MIP-3α) (CCL20) and MIP-3β (CCL19) by human peripheral blood neutrophils in response to microbial pathogens. Infect Immun 2003 71: 524 6.
    • (2003) Infect Immun , vol.71 , pp. 524-6
    • Akahoshi, T.1    Sasahara, T.2    Namai, R.3    Matsui, T.4    Watabe, H.5    Kitasato, H.6    Inoue, M.7    Kondo, H.8
  • 42
    • 27644565806 scopus 로고    scopus 로고
    • Serum levels of TNF-α, IFN-γ, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity
    • Arican O, Aral M, Sasmaz S, Ciragil P. Serum levels of TNF-α, IFN-γ, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity. Mediators Inflamm 2005 2005: 273 9.
    • (2005) Mediators Inflamm , vol.2005 , pp. 273-9
    • Arican, O.1    Aral, M.2    Sasmaz, S.3    Ciragil, P.4
  • 44
    • 0034881019 scopus 로고    scopus 로고
    • Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals
    • Ballif BA, Blenis J. Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals. Cell Growth Differ 2001 12: 397 408.
    • (2001) Cell Growth Differ , vol.12 , pp. 397-408
    • Ballif, B.A.1    Blenis, J.2
  • 45
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signaling cascades
    • Chang L, Karin M. Mammalian MAP kinase signaling cascades. Nature 2001 410: 37 40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 48
    • 1542406446 scopus 로고    scopus 로고
    • NOX enzymes and the biology of reactive oxygen
    • Lambeth JD. NOX enzymes and the biology of reactive oxygen. Nat Rev Immunol 2004 4: 181 9.
    • (2004) Nat Rev Immunol , vol.4 , pp. 181-9
    • Lambeth, J.D.1
  • 49
    • 33845724468 scopus 로고    scopus 로고
    • Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function
    • Fialkow L, Wang Y, Downey GP. Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function. Free Radic Biol Med 2007 42: 153 64.
    • (2007) Free Radic Biol Med , vol.42 , pp. 153-64
    • Fialkow, L.1    Wang, Y.2    Downey, G.P.3
  • 50
    • 0024370068 scopus 로고
    • Purification and characterization of human neutrophil peptide 4, a novel member of the defensin family
    • Wilde CG, Griffith JE, Marra NN, Snable JL, Scott RW. Purification and characterization of human neutrophil peptide 4, a novel member of the defensin family. J Biol Chem 1989 264: 11200 3.
    • (1989) J Biol Chem , vol.264 , pp. 11200-3
    • Wilde, C.G.1    Griffith, J.E.2    Marra, N.N.3    Snable, J.L.4    Scott, R.W.5
  • 51
    • 0141799911 scopus 로고    scopus 로고
    • Defensins: Antimicrobial peptides of innate immunity
    • Ganz T. Defensins: antimicrobial peptides of innate immunity. Nat Rev Immunol 2003 3: 710 20.
    • (2003) Nat Rev Immunol , vol.3 , pp. 710-20
    • Ganz, T.1
  • 52
    • 0026609053 scopus 로고
    • Characterization of defensin precursors in mature human neutrophils
    • Harwig SS, Park AS, Lehrer RI. Characterization of defensin precursors in mature human neutrophils. Blood 1992 79: 1532 7.
    • (1992) Blood , vol.79 , pp. 1532-7
    • Harwig, S.S.1    Park, A.S.2    Lehrer, R.I.3
  • 54
    • 0018382875 scopus 로고
    • RNA and protein synthesis in human peripheral blood polymorphonuclear leukocytes
    • Granelli-Piperno A, Vassalli JD, Reich E. RNA and protein synthesis in human peripheral blood polymorphonuclear leukocytes. J Exp Med 1979 149: 284 9.
    • (1979) J Exp Med , vol.149 , pp. 284-9
    • Granelli-Piperno, A.1    Vassalli, J.D.2    Reich, E.3
  • 55
    • 0021558067 scopus 로고
    • Chemoattractant receptors on phagocytic cells
    • Snyderman R, Pike MC. Chemoattractant receptors on phagocytic cells. Annu Rev Immunol 1984 2: 257 81.
    • (1984) Annu Rev Immunol , vol.2 , pp. 257-81
    • Snyderman, R.1    Pike, M.C.2
  • 56
    • 0022972640 scopus 로고
    • Model for leukocyte regulation by chemoattractant receptors: Roles of a guanine nucleotide regulatory protein and polyphosphoinositide metabolism
    • Snyderman R, Smith CD, Verghese MW. Model for leukocyte regulation by chemoattractant receptors: roles of a guanine nucleotide regulatory protein and polyphosphoinositide metabolism. J Leukoc Biol 1986 40: 785 800.
    • (1986) J Leukoc Biol , vol.40 , pp. 785-800
    • Snyderman, R.1    Smith, C.D.2    Verghese, M.W.3
  • 57
    • 33645051715 scopus 로고    scopus 로고
    • Antimicrobial skin peptides and proteins
    • Schröder JM, Harder J. Antimicrobial skin peptides and proteins. Cell Mol Life Sci 2006 63: 469 86.
    • (2006) Cell Mol Life Sci , vol.63 , pp. 469-86
    • Schröder, J.M.1    Harder, J.2


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