Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: A potential P450 and lipoxygenase interaction

Journal of Lipid Research

Volumn 55, Issue 12, 2015, Pages 2587-2596

  Teder, Tarvi ^a,b   Boeglin, William E ^a   Brash, Alan R ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TALLINN UNIVERSITY OF TECHNOLOGY   (Estonia)

Author keywords

Cytochrome P450; Epoxyeicosatrienoic acid; Fatty acid epoxide; Fatty acid physical chemistry; Lipids chemistry; Lipoxygenase; Monocyclic peroxide; Nuclear magnetic resonance

Indexed keywords

13 HYDROPEROXY 15,16 EPOXIDE; 13,15 ENDOPEROXY 16 HYDROXYOCTADECA 9,11 DIENOIC ACID; 14,15 EPOXY 5,8,11 ICOSATRIENOIC ACID; 15,16 EPOXY ALPHA LINOLEIC ACID; CYTOCHROME P450; ELECTROPHILE; ENDOPEROXIDE; FATTY ACID; LIPOXYGENASE; NUCLEOPHILE; UNCLASSIFIED DRUG; 14,15-EPOXY-5,8,11-EICOSATRIENOIC ACID; ALOX15 PROTEIN, HUMAN; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; DIHOMO GAMMA LINOLENIC ACID; EPOXIDE; ICOSANOID; LINOLENIC ACID; LIPID PEROXIDE; LIPOXYGENASE L-1; RECOMBINANT PROTEIN; SOYBEAN PROTEIN;

ARTICLE; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; OXYGENATION; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS; ANALOGS AND DERIVATIVES; ANIMAL; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; ELECTROSPRAY MASS SPECTROMETRY; ENZYMOLOGY; GENETICS; HUMAN; HYDROXYLATION; MASS FRAGMENTOGRAPHY; MOUSE; NUCLEAR MAGNETIC RESONANCE; OXIDATION REDUCTION REACTION; STEREOISOMERISM; THROMBOCYTE;

8,11,14-EICOSATRIENOIC ACID; ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; BIOCATALYSIS; BLOOD PLATELETS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EICOSANOIDS; EPOXY COMPOUNDS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; HYDROXYLATION; LINOLENIC ACIDS; LIPID PEROXIDES; LIPOXYGENASE; MICE; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OXIDATION-REDUCTION; RECOMBINANT PROTEINS; SOYBEAN PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEREOISOMERISM;

EID: 84919740745     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M054072     Document Type: Article

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