Yeast DNA ligase IV mutations reveal a nonhomologous end joining function of BRCT1 distinct from XRCC4/Lif1 binding

DNA Repair

Volumn 24, Issue , 2014, Pages 37-45

  Chiruvella, Kishore K ^a,b   Renard, Brian M ^a   Birkeland, Shanda R ^a,c   Sunder, Sham ^a   Liang, Zhuobin ^a   Wilson, Thomas E ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b STOCKHOLM UNIVERSITY   (Sweden)

^c AMDx Laboratory Sciences Inc   (United States)

Author keywords

BRCT domain; DNA ligase IV; Double strand break; Nonhomologous end joining; Separation of function

Indexed keywords

BRCA1 C TERMINAL PROTEIN; LIF1 PROTEIN; PEPTIDES AND PROTEINS; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; UNCLASSIFIED DRUG; XRCC4 PROTEIN; DNA BINDING PROTEIN; DNA LIGASE; DNA LIGASE (ATP); LIF1 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; XRCC4 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; DNA END JOINING REPAIR; GENE MUTATION; NONHUMAN; PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION; YEAST; CHEMISTRY; DOUBLE STRANDED DNA BREAK; GENETICS; METABOLISM; MUTATION; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE;

DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA LIGASES; DNA-BINDING PROTEINS; MUTATION; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84919730062     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2014.10.003     Document Type: Article

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