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Volumn 9, Issue 12, 2014, Pages

Integrated analysis of whole genome and transcriptome sequencing reveals diverse transcriptomic aberrations driven by somatic genomic changes in liver cancers

(31)  Shiraishi, Yuichi a   Fujimoto, Akihiro b   Furuta, Mayuko b   Tanaka, Hiroko a   Chiba, Ken Ichi a   Boroevich, Keith A b   Abe, Tetsuo b   Kawakami, Yoshiiku c   Ueno, Masaki d   Gotoh, Kunihito e   Ariizumi, Shun Ichi f   Shibuya, Tetsuo a   Nakano, Kaoru b   Sasaki, Aya b   Maejima, Kazuhiro b   Kitada, Rina b   Hayami, Shinya d   Shigekawa, Yoshinobu d   Marubashi, Shigeru e   Yamada, Terumasa e   more..


Author keywords

[No Author keywords available]

Indexed keywords

ARID2 GENE; ARTICLE; AXIN1 GENE; CDK15 GENE; CLINICAL ARTICLE; CPS1 GENE; EXON; FN1 GENE; GENE; GENE EXPRESSION; GENE FREQUENCY; GENE MUTATION; GENE OVEREXPRESSION; GENETIC VARIABILITY; GENOME ANALYSIS; HEPATITIS B VIRUS; HNF4A GENE; HUMAN; INTRON; LIVER CELL CARCINOMA; MISSENSE MUTATION; MLL4 GENE; NONSENSE MUTATION; RNA EDITING; RNA SEQUENCE; RPS6KA3 GENE; SEQUENCE ALIGNMENT; SOMATIC MUTATION; TERT GENE; TP53 GENE; TSC1 GENE; VIRUS GENOME; CASE CONTROL STUDY; CLONAL EVOLUTION; GENE EXPRESSION REGULATION; GENETICS; HUMAN GENOME; LIVER TUMOR; METABOLISM; MUTATION; ONCOGENE;

EID: 84919686143     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0114263     Document Type: Article
Times cited : (72)

References (38)
  • 1
    • 80053088189 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • El-Serag HB (2011) Hepatocellular carcinoma. N Engl J Med 365: 1118-1127.
    • (2011) N Engl J Med , vol.365 , pp. 1118-1127
    • El-Serag, H.B.1
  • 2
    • 33747830764 scopus 로고    scopus 로고
    • Hepatocellular carcinoma pathogenesis: From genes to environment
    • Farazi PA, DePinho RA (2006) Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev Cancer 6: 674-687.
    • (2006) Nat Rev Cancer , vol.6 , pp. 674-687
    • Farazi, P.A.1    DePinho, R.A.2
  • 3
    • 77956838065 scopus 로고    scopus 로고
    • Advances in understanding cancer genomes through second-generation sequencing
    • Meyerson M, Gabriel S, Getz G (2010) Advances in understanding cancer genomes through second-generation sequencing. Nat Rev Genet 11: 685-696.
    • (2010) Nat Rev Genet , vol.11 , pp. 685-696
    • Meyerson, M.1    Gabriel, S.2    Getz, G.3
  • 4
    • 84862976633 scopus 로고    scopus 로고
    • Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
    • Fujimoto A, Totoki Y, Abe T, Boroevich KA, Hosoda F, et al. (2012) Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat Genet 44: 760-764.
    • (2012) Nat Genet , vol.44 , pp. 760-764
    • Fujimoto, A.1    Totoki, Y.2    Abe, T.3    Boroevich, K.A.4    Hosoda, F.5
  • 5
    • 84866868120 scopus 로고    scopus 로고
    • Exome sequencing of hepatitis B virusassociated hepatocellular carcinoma
    • Huang J, Deng Q, Wang Q, Li KY, Dai JH, et al. (2012) Exome sequencing of hepatitis B virusassociated hepatocellular carcinoma. Nat Genet 44: 1117-1121.
    • (2012) Nat Genet , vol.44 , pp. 1117-1121
    • Huang, J.1    Deng, Q.2    Wang, Q.3    Li, K.Y.4    Dai, J.H.5
  • 6
    • 84862999344 scopus 로고    scopus 로고
    • Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma
    • Sung WK, Zheng H, Li S, Chen R, Liu X, et al. (2012) Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet 44: 765-769.
    • (2012) Nat Genet , vol.44 , pp. 765-769
    • Sung, W.K.1    Zheng, H.2    Li, S.3    Chen, R.4    Liu, X.5
  • 7
    • 84872038565 scopus 로고    scopus 로고
    • Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach
    • Ding D, Lou X, Hua D, Yu W, Li L, et al. (2012) Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet 8: e1003065.
    • (2012) PLoS Genet , vol.8 , pp. e1003065
    • Ding, D.1    Lou, X.2    Hua, D.3    Yu, W.4    Li, L.5
  • 8
    • 84859553856 scopus 로고    scopus 로고
    • The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients
    • Jiang Z, Jhunjhunwala S, Liu J, Haverty PM, Kennemer MI, et al. (2012) The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients. Genome Res 22: 593-601.
    • (2012) Genome Res , vol.22 , pp. 593-601
    • Jiang, Z.1    Jhunjhunwala, S.2    Liu, J.3    Haverty, P.M.4    Kennemer, M.I.5
  • 9
    • 7444220147 scopus 로고    scopus 로고
    • Aberrant and alternative splicing in cancer
    • Venables JP (2004) Aberrant and alternative splicing in cancer. Cancer Res 64: 7647-7654.
    • (2004) Cancer Res , vol.64 , pp. 7647-7654
    • Venables, J.P.1
  • 10
    • 78049416081 scopus 로고    scopus 로고
    • Alternative pre-mRNA splicing regulation in cancer: Pathways and programs unhinged
    • David CJ, Manley JL (2010) Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged. Genes Dev 24: 2343-2364.
    • (2010) Genes Dev , vol.24 , pp. 2343-2364
    • David, C.J.1    Manley, J.L.2
  • 11
    • 33947581390 scopus 로고    scopus 로고
    • The impact of translocations and gene fusions on cancer causation
    • Mitelman F, Johansson B, Mertens F (2007) The impact of translocations and gene fusions on cancer causation. Nat Rev Cancer 7: 233-245.
    • (2007) Nat Rev Cancer , vol.7 , pp. 233-245
    • Mitelman, F.1    Johansson, B.2    Mertens, F.3
  • 12
    • 84868309107 scopus 로고    scopus 로고
    • The transcriptional landscape and mutational profile of lung adenocarcinoma
    • Seo JS, Ju YS, Lee WC, Shin JY, Lee JK, et al. (2012) The transcriptional landscape and mutational profile of lung adenocarcinoma. Genome Res 22: 2109-2119.
    • (2012) Genome Res , vol.22 , pp. 2109-2119
    • Seo, J.S.1    Ju, Y.S.2    Lee, W.C.3    Shin, J.Y.4    Lee, J.K.5
  • 13
    • 84870495530 scopus 로고    scopus 로고
    • Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events
    • Liu J, Lee W, Jiang Z, Chen Z, Jhunjhunwala S, et al. (2012) Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events. Genome Res 22: 2315-2327.
    • (2012) Genome Res , vol.22 , pp. 2315-2327
    • Liu, J.1    Lee, W.2    Jiang, Z.3    Chen, Z.4    Jhunjhunwala, S.5
  • 15
    • 0031005031 scopus 로고    scopus 로고
    • BCL8, a novel gene involved in translocations affecting band 15q11-13 in diffuse large-cell lymphoma
    • Dyomin VG, Rao PH, Dalla-Favera R, Chaganti RS (1997) BCL8, a novel gene involved in translocations affecting band 15q11-13 in diffuse large-cell lymphoma. Proc Natl Acad Sci U S A 94: 5728-5732.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 5728-5732
    • Dyomin, V.G.1    Rao, P.H.2    Dalla-Favera, R.3    Chaganti, R.S.4
  • 17
    • 84876588616 scopus 로고    scopus 로고
    • An empirical Bayesian framework for somatic mutation detection from cancer genome sequencing data
    • Shiraishi Y, Sato Y, Chiba K, Okuno Y, Nagata Y, et al. (2013) An empirical Bayesian framework for somatic mutation detection from cancer genome sequencing data. Nucleic Acids Res.
    • (2013) Nucleic Acids Res
    • Shiraishi, Y.1    Sato, Y.2    Chiba, K.3    Okuno, Y.4    Nagata, Y.5
  • 18
    • 77952293063 scopus 로고    scopus 로고
    • Functions and regulation of RNA editing by ADAR deaminases
    • Nishikura K (2010) Functions and regulation of RNA editing by ADAR deaminases. Annu Rev Biochem 79: 321-349.
    • (2010) Annu Rev Biochem , vol.79 , pp. 321-349
    • Nishikura, K.1
  • 20
    • 84861625981 scopus 로고    scopus 로고
    • Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
    • Guichard C, Amaddeo G, Imbeaud S, Ladeiro Y, Pelletier L, et al. (2012) Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. Nat Genet 44: 694-698.
    • (2012) Nat Genet , vol.44 , pp. 694-698
    • Guichard, C.1    Amaddeo, G.2    Imbeaud, S.3    Ladeiro, Y.4    Pelletier, L.5
  • 21
    • 83255162659 scopus 로고    scopus 로고
    • An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis
    • Hatziapostolou M, Polytarchou C, Aggelidou E, Drakaki A, Poultsides GA, et al. (2011) An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis. Cell 147: 1233-1247.
    • (2011) Cell , vol.147 , pp. 1233-1247
    • Hatziapostolou, M.1    Polytarchou, C.2    Aggelidou, E.3    Drakaki, A.4    Poultsides, G.A.5
  • 22
    • 77957344834 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4 alpha suppresses the development of hepatocellular carcinoma
    • Ning BF, Ding J, Yin C, ZhongW, Wu K, et al. (2010) Hepatocyte nuclear factor 4 alpha suppresses the development of hepatocellular carcinoma. Cancer Res 70: 7640-7651.
    • (2010) Cancer Res , vol.70 , pp. 7640-7651
    • Ning, B.F.1    Ding, J.2    Yin, C.3    Zhong, W.4    Wu, K.5
  • 23
    • 0036207384 scopus 로고    scopus 로고
    • Listening to silence and understanding nonsense: Exonic mutations that affect splicing
    • Cartegni L, Chew SL, Krainer AR (2002) Listening to silence and understanding nonsense: exonic mutations that affect splicing. Nat Rev Genet 3: 285-298.
    • (2002) Nat Rev Genet , vol.3 , pp. 285-298
    • Cartegni, L.1    Chew, S.L.2    Krainer, A.R.3
  • 24
    • 80052964856 scopus 로고    scopus 로고
    • Understanding the contribution of synonymous mutations to human disease
    • Sauna ZE, Kimchi-Sarfaty C (2011) Understanding the contribution of synonymous mutations to human disease. Nat Rev Genet 12: 683-691.
    • (2011) Nat Rev Genet , vol.12 , pp. 683-691
    • Sauna, Z.E.1    Kimchi-Sarfaty, C.2
  • 25
    • 84872296411 scopus 로고    scopus 로고
    • Next-generation sequencing reveals deep intronic cryptic ABCC8 and HADH splicing founder mutations causing hyperinsulinism by pseudoexon activation
    • Flanagan SE, Xie W, Caswell R, Damhuis A, Vianey-Saban C, et al. (2013) Next-generation sequencing reveals deep intronic cryptic ABCC8 and HADH splicing founder mutations causing hyperinsulinism by pseudoexon activation. Am J Hum Genet 92: 131-136.
    • (2013) Am J Hum Genet , vol.92 , pp. 131-136
    • Flanagan, S.E.1    Xie, W.2    Caswell, R.3    Damhuis, A.4    Vianey-Saban, C.5
  • 26
    • 79951830082 scopus 로고    scopus 로고
    • DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma
    • Liu H, Dong H, Robertson K, Liu C (2011) DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma. Am J Pathol 178: 652-661
    • (2011) Am J Pathol , vol.178 , pp. 652-661
    • Liu, H.1    Dong, H.2    Robertson, K.3    Liu, C.4
  • 27
    • 84859090262 scopus 로고    scopus 로고
    • Chronic activation of mTOR complex 1 is sufficient to cause hepatocellular carcinoma in mice
    • Menon S, Yecies JL, Zhang HH, Howell JJ, Nicholatos J, et al. (2012) Chronic activation of mTOR complex 1 is sufficient to cause hepatocellular carcinoma in mice. Sci Signal 5: ra24.
    • (2012) Sci Signal , vol.5 , pp. ra24
    • Menon, S.1    Yecies, J.L.2    Zhang, H.H.3    Howell, J.J.4    Nicholatos, J.5
  • 29
    • 33845902802 scopus 로고    scopus 로고
    • Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment
    • Merz C, Urlaub H, Will CL, Lührmann R (2007) Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment. RNA 13: 116-128.
    • (2007) RNA , vol.13 , pp. 116-128
    • Merz, C.1    Urlaub, H.2    Will, C.L.3    Lührmann, R.4
  • 30
    • 84860325854 scopus 로고    scopus 로고
    • Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response
    • Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, et al. (2012) Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response. Mol Cell 46: 212-225.
    • (2012) Mol Cell , vol.46 , pp. 212-225
    • Beli, P.1    Lukashchuk, N.2    Wagner, S.A.3    Weinert, B.T.4    Olsen, J.V.5
  • 31
    • 0037663314 scopus 로고    scopus 로고
    • Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene
    • Paterlini-Bréchot P, Saigo K, Murakami Y, Chami M, Gozuacik D, et al. (2003) Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene. Oncogene 22: 3911-3916.
    • (2003) Oncogene , vol.22 , pp. 3911-3916
    • Paterlini-Bréchot, P.1    Saigo, K.2    Murakami, Y.3    Chami, M.4    Gozuacik, D.5
  • 33
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with Burrows-Wheeler transform
    • Li H, Durbin R (2009) Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25: 1754-1760.
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 35
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead B, Trapnell C, Pop M, Salzberg SL (2009) Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 10: R25.
    • (2009) Genome Biol , vol.10 , pp. R25
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 36
    • 0036226603 scopus 로고    scopus 로고
    • BLAT - The BLAST-like alignment tool
    • Kent WJ (2002) BLAT-the BLAST-like alignment tool. Genome Res 12: 656-664.
    • (2002) Genome Res , vol.12 , pp. 656-664
    • Kent, W.J.1
  • 38
    • 0022550119 scopus 로고
    • A compensatory base change in U1 snRNA suppresses a 5′ splice site mutation
    • Zhuang Y, Weiner AM (1986) A compensatory base change in U1 snRNA suppresses a 5′ splice site mutation. Cell 46: 827-835.
    • (1986) Cell , vol.46 , pp. 827-835
    • Zhuang, Y.1    Weiner, A.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.