Protein tyrosine kinase 6 mediates TNFα-induced endothelial barrier dysfunction

Biochemical and Biophysical Research Communications

Volumn 456, Issue 1, 2015, Pages 190-196

  Haines, R J ^a   Beard, R S ^a   Wu, M H ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Endothelial barrier function; p120 Catenin; PTK6; VE cadherin

Indexed keywords

CATENIN; MESSENGER RNA; PROTEIN P120; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE 6; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; CADHERIN; DELTA CATENIN; LEUKOCYTE ANTIGEN; PTK6 PROTEIN, MOUSE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL JUNCTION; CELL MEMBRANE; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; IN VITRO STUDY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; ANIMAL; CELL COMMUNICATION; CELL NUCLEUS; ENDOTHELIUM; GENE EXPRESSION REGULATION; INFLAMMATION; METABOLISM; PATHOLOGY; PERMEABILITY; PHYSIOLOGY; PROTEIN TRANSPORT;

ANIMALS; ANTIGENS, CD; CADHERINS; CATENINS; CELL COMMUNICATION; CELL MEMBRANE; CELL NUCLEUS; ENDOTHELIUM; GENE EXPRESSION REGULATION; INFLAMMATION; MICE; PERMEABILITY; PROTEIN TRANSPORT; PROTEIN-TYROSINE KINASES; RNA, MESSENGER; RNA, SMALL INTERFERING; SRC-FAMILY KINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84919683036     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.11.057     Document Type: Article

References (32)

1. S.Y. Yuan, and R.R. Rigor Regulation of Endothelial Barrier Function 2010 Morgan & Claypool Life Sciences San Rafael (CA)
2. D. Mehta, and A.B. Malik Signaling mechanisms regulating endothelial permeability Physiol. Rev. 86 2006 279 367
3. R.H. Demling The burn edema process: current concepts J. Burn Care Rehabil. 26 2005 207 227
4. C. Sun, M.H. Wu, and S.Y. Yuan Nonmuscle myosin light-chain kinase deficiency attenuates atherosclerosis in apolipoprotein e-deficient mice via reduced endothelial barrier dysfunction and monocyte migrationclinical perspective Circulation 124 2011 48 57
5. T. Tadros, D.L. Traber, J.P. Heggers, and D.N. Herndon Effects of interleukin-1alpha administration on intestinal ischemia and reperfusion injury, mucosal permeability, and bacterial translocation in burn and sepsis Ann. Surg. 237 2003 101 109
6. P. Kumar, Q. Shen, C.D. Pivetti, E.S. Lee, M.H. Wu, and S.Y. Yuan Molecular mechanisms of endothelial hyperpermeability: implications in inflammation Expert Rev. Mol. Med. 11 2009
7. R.S. Beard, R.J. Haines, K.Y. Wu, J.J. Reynolds, S.M. Davis, J.E. Elliott, N.L. Malinin, V. Chatterjee, B.J. Cha, M.H. Wu, and S.Y. Yuan Non-muscle Mlck is required for beta-catenin- and FoxO1-dependent downregulation of Cldn5 in IL-1 beta-mediated barrier dysfunction in brain endothelial cells J. Cell Sci. 127 2014 1840 1853
8. A. Lenz, G.A. Franklin, and W.G. Cheadle Systemic inflammation after trauma Injury 38 2007 1336 1345
9. K.J. Tracey, B. Beutler, S.F. Lowry, J. Merryweather, S. Wolpe, I.W. Milsark, R.J. Hariri, T.J. Fahey 3rd, A. Zentella, and J.D. Albert Shock and tissue injury induced by recombinant human cachectin Science 234 1986 470 474
10. D.J. Angelini, S.W. Hyun, D.N. Grigoryev, P. Garg, P. Gong, I.S. Singh, A. Passaniti, J.D. Hasday, and S.E. Goldblum TNF-alpha increases tyrosine phosphorylation of vascular endothelial cadherin and opens the paracellular pathway through fyn activation in human lung endothelia Am. J. Physiol. Lung Cell. Mol. Physiol. 291 2006 L1232 1245
11. H. Gong, X. Gao, S. Feng, M.R. Siddiqui, A. Garcia, M.G. Bonini, Y. Komarova, S.M. Vogel, D. Mehta, and A.B. Malik Evidence of a common mechanism of disassembly of adherens junctions through Galpha13 targeting of VE-cadherin J. Exp. Med. 211 2014 579 591
12. K. Xiao, J. Garner, K.M. Buckley, P.A. Vincent, C.M. Chiasson, E. Dejana, V. Faundez, and A.P. Kowalczyk P120-Catenin regulates clathrin-dependent endocytosis of VE-cadherin Mol. Biol. Cell 16 2005 5141 5151
13. P.M. Brauer, and A.L. Tyner Building a better understanding of the intracellular tyrosine kinase PTK6 - BRK by BRK Biochim. Biophys. Acta 2010 1806 66 73
14. Y. Zheng, Z. Wang, W. Bie, P.M. Brauer, B.E. Perez White, J. Li, V. Nogueira, P. Raychaudhuri, B.E. Hay, D.A. Tonetti, V. Macias, A. Kajdacsy-Balla, and A.L. Tyner PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer Cancer Res. 73 2013 5426 5437
15. H.Y. Chen, C.H. Shen, Y.T. Tsai, F.C. Lin, Y.P. Huang, and R.H. Chen Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin Mol. Cell. Biol. 24 2004 10558 10572
16. H.L. Palka-Hamblin, J.J. Gierut, W. Bie, P.M. Brauer, Y. Zheng, J.M. Asara, and A.L. Tyner Identification of β-catenin as a target of the intracellular tyrosine kinase PTK6 J. Cell Sci. 123 2010 236 245
17. Y. Zheng, J. Gierut, Z. Wang, J. Miao, J.M. Asara, and A.L. Tyner Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT Oncogene 32 2013 4304 4312
18. M.P. Kim, S.I. Park, S. Kopetz, and G.E. Gallick Src family kinases as mediators of endothelial permeability: effects on inflammation and metastasis Cell Tissue Res. 335 2009 249 259
19. E. Hong, J. Shin, E. Bang, M.H. Kim, S.T. Lee, and W. Lee Complete sequence-specific 1H, 13C and 15N resonance assignments of the human PTK6 SH2 domain J. Biomol. NMR 19 2001 291 292
20. H. Kim, J. Jung, E.S. Lee, Y.C. Kim, W. Lee, and S.T. Lee Molecular dissection of the interaction between the SH3 domain and the SH2-Kinase Linker region in PTK6 Biochem. Biophys. Res. Commun. 362 2007 829 834
21. H. Qiu, and W.T. Miller Regulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibition J. Biol. Chem. 277 2002 34634 34641
22. R.H. Whitehead, P.S. Robinson, J.A. Williams, W. Bie, A.L. Tyner, and J.L. Franklin Conditionally immortalized colonic epithelial cell line from a Ptk6 null mouse that polarizes and differentiates in vitro J. Gastroenterol. Hepatol. 23 2008 1119 1124
23. C. Tiruppathi, A.B. Malik, P.J. Del Vecchio, C.R. Keese, and I. Giaever Electrical method for detection of endothelial cell shape change in real time: assessment of endothelial barrier function Proc. Natl. Acad. Sci. U.S.A. 89 1992 7919 7923
24. C. Sun, M.H. Wu, M. Guo, M.L. Day, E.S. Lee, and S.Y. Yuan ADAM15 regulates endothelial permeability and neutrophil migration via Src/ERK1/2 signalling Cardiovasc. Res. 87 2010 348 355
25. M.D. Potter, S. Barbero, and D.A. Cheresh Tyrosine phosphorylation of VE-cadherin prevents binding of p120- and β-catenin and maintains the cellular mesenchymal state J. Biol. Chem. 280 2005 31906 31912
26. K. Hatanaka, M. Simons, and M. Murakami Phosphorylation of VE-cadherin controls endothelial phenotypes via p120-catenin coupling and Rac1 activation Am. J. Physiol. Heart Circ. Physiol. 300 2011 H162 172
27. M.A. Davis, R.C. Ireton, and A.B. Reynolds A core function for p120-catenin in cadherin turnover J. Cell Biol. 163 2003 525 534
28. D. Okutani, M. Lodyga, B. Han, and M. Liu Src protein tyrosine kinase family and acute inflammatory responses Am. J. Physiol. Lung Cell. Mol. Physiol. 291 2006 L129 141
29. J.H. Tinsley, M.H. Wu, W. Ma, A.C. Taulman, and S.Y. Yuan Activated neutrophils induce hyperpermeability and phosphorylation of adherens junction proteins in coronary venular endothelial cells J. Biol. Chem. 274 1999 24930 24934
30. J. Gavard, and J.S. Gutkind VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin Nat. Cell Biol. 8 2006 1223 1234
31. S. Weis, J. Cui, L. Barnes, and D. Cheresh Endothelial barrier disruption by VEGF-mediated Src activity potentiates tumor cell extravasation and metastasis J. Cell Biol. 167 2004 223 229
32. F. Orsenigo, C. Giampietro, A. Ferrari, M. Corada, A. Galaup, S. Sigismund, G. Ristagno, L. Maddaluno, G.Y. Koh, D. Franco, V. Kurtcuoglu, D. Poulikakos, P. Baluk, D. McDonald, M. Grazia Lampugnani, and E. Dejana Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo Nat. Commun. 3 2012 1208