Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT

Oncogene

Volumn 32, Issue 36, 2013, Pages 4304-4312

  Zheng, Y ^a   Gierut, J ^a   Wang, Z ^a   Miao, J ^a   Asara, J M ^b,c   Tyner, A L ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

AKT; anoikis; BRK; FAK; PTK6; Sik

Indexed keywords

FOCAL ADHESION KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN KINASE FYN; PROTEIN KINASE P60; PROTEIN KINASE YES; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE 6; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOIKIS; ARTICLE; CELL CULTURE; CELL LINE; CELL MEMBRANE; CELL PROLIFERATION; CELL PROTECTION; CELL STRUCTURE; CELL SURVIVAL; CELL SUSPENSION; CELL TRANSFORMATION; COLON CANCER; CONTACT INHIBITION; CONTROLLED STUDY; EMBRYO CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MALE; MASS SPECTROMETRY; MOUSE; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE EPITHELIUM; PROTEIN EXPRESSION; TUMOR XENOGRAFT;

ANIMALS; ANOIKIS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; ENZYME ACTIVATION; FIBROBLASTS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE KNOCKDOWN TECHNIQUES; HUMANS; MALE; MICE; NEOPLASM PROTEINS; PHOSPHORYLATION; PROSTATIC NEOPLASMS; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; SUBSTRATE SPECIFICITY;

MURINAE; MUS;

EID: 84883743643     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.427     Document Type: Article

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