Non-muscle Mlck is required for ß-catenin- and FoxO1-dependent downregulation of Cldn5 in IL-1ß-mediated barrier dysfunction in brain endothelial cells

Journal of Cell Science

Volumn 127, Issue 8, 2014, Pages 1840-1853

  Beard, Richard S ^a   Haines, Ricci J ^a   Wu, Kevin Y ^a   Reynolds, Jason J ^a   Davis, Stephanie M ^a   Elliott, John E ^a   Malinin, Nikolay L ^a   Chatterjee, Victor ^a   Cha, Byeong J ^a   Wu, Mack H ^a   Yuan, Sarah Y ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Blood brain barrier; Claudin 5; FoxO1; IL 1 ; Neuroinflammation; Non muscle myosin light chain kinase; catenin

Indexed keywords

BETA CATENIN; CLAUDIN 5; INTERLEUKIN 1BETA; MYOSIN LIGHT CHAIN KINASE; TRANSCRIPTION FACTOR FKHR; CADHERIN; CLDN5 PROTEIN, MOUSE; CTNNB1 PROTEIN, MOUSE; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; LEUKOCYTE ANTIGEN; NON-MUSCLE MYOSIN LIGHT-CHAIN KINASE, MOUSE; VASCULAR ENDOTHELIAL CADHERIN;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CELL; CELL ISOLATION; CONTROLLED STUDY; DOWN REGULATION; GENE REPRESSION; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NEUROMODULATION; NONHUMAN; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN FUNCTION; TRANSCRIPTION REGULATION; ANIMAL; BRAIN; CELL CULTURE; ENDOTHELIUM CELL; GENETICS; METABOLISM; MICROVASCULATURE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REGULATORY SEQUENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; VASCULAR ENDOTHELIUM; VASCULARIZATION;

ANIMALS; ANTIGENS, CD; BETA CATENIN; BLOOD-BRAIN BARRIER; BRAIN; CADHERINS; CELLS, CULTURED; CLAUDIN-5; DOWN-REGULATION; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FORKHEAD TRANSCRIPTION FACTORS; INTERLEUKIN-1BETA; MICE; MICROVESSELS; MYOSIN-LIGHT-CHAIN KINASE; REGULATORY SEQUENCES, NUCLEIC ACID; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 84898892897     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.144550     Document Type: Article

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