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Volumn 20, Issue 24, 2014, Pages 6346-6356

Circulating pegfr is a candidate response biomarker of cetuximab therapy in colorectal cancer

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY; PROTEOME; RAS PROTEIN; TUMOR MARKER;

EID: 84919622759     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-14-0361     Document Type: Article
Times cited : (23)

References (34)
  • 1
    • 84862999938 scopus 로고    scopus 로고
    • Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
    • Misale S, Yaeger R, Hobor S, Scala E, Janakiraman M, Liska D, et al. Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer. Nature 2012;486:532-36.
    • (2012) Nature , vol.486 , pp. 532-536
    • Misale, S.1    Yaeger, R.2    Hobor, S.3    Scala, E.4    Janakiraman, M.5    Liska, D.6
  • 2
    • 84863000299 scopus 로고    scopus 로고
    • The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers
    • Diaz LA Jr, Williams RT, Wu J, Kinde I, Hecht JR, Berlin J, et al. The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers. Nature 2012;486:537-40.
    • (2012) Nature , vol.486 , pp. 537-540
    • Diaz, L.A.1    Williams, R.T.2    Wu, J.3    Kinde, I.4    Hecht, J.R.5    Berlin, J.6
  • 3
    • 42649145667 scopus 로고    scopus 로고
    • Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
    • Amado RG, Wolf M, Peeters M, Van Cutsem E, Siena S, Freeman DJ, et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008;26:1626-34.
    • (2008) J Clin Oncol , vol.26 , pp. 1626-1634
    • Amado, R.G.1    Wolf, M.2    Peeters, M.3    Van Cutsem, E.4    Siena, S.5    Freeman, D.J.6
  • 4
    • 51649120733 scopus 로고    scopus 로고
    • KRAS status and efficacy of first-line treatment of patients with metastatic colorectal cancer (mCRC) with FOLFOX with or without cetuximab: The OPUS experience
    • Bokemeyer C, Bondarenko I, Hartmann JT, De Braud FG, Volovat C, et al. KRAS status and efficacy of first-line treatment of patients with metastatic colorectal cancer (mCRC) with FOLFOX with or without cetuximab: the OPUS experience. J Clin Oncol 2008;26:4000
    • (2008) J Clin Oncol , vol.26 , pp. 4000
    • Bokemeyer, C.1    Bondarenko, I.2    Hartmann, J.T.3    De Braud, F.G.4    Volovat, C.5
  • 5
    • 40149088765 scopus 로고    scopus 로고
    • KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab
    • De Roock W, Piessevaux H, De Schutter J, Janssens M, De Hertogh G, Personeni N, et al. KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab. Ann Oncol 2008;19:508-15.
    • (2008) Ann Oncol , vol.19 , pp. 508-515
    • De Roock, W.1    Piessevaux, H.2    De Schutter, J.3    Janssens, M.4    De Hertogh, G.5    Personeni, N.6
  • 6
  • 8
    • 34548238762 scopus 로고    scopus 로고
    • Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab
    • Khambata-Ford S, Garrett CR, Meropol NJ, Basik M, Harbison CT, Wu S, et al. Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab. J Clin Oncol 2007;25:3230-37.
    • (2007) J Clin Oncol , vol.25 , pp. 3230-3237
    • Khambata-Ford, S.1    Garrett, C.R.2    Meropol, N.J.3    Basik, M.4    Harbison, C.T.5    Wu, S.6
  • 9
    • 38649099966 scopus 로고    scopus 로고
    • KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab
    • Lìevre A, Bachet JB, Boige V, Cayre A, Le Corre D, Buc E, et al. KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab. J Clin Oncol 2008;26:374-79.
    • (2008) J Clin Oncol , vol.26 , pp. 374-379
    • Lìevre, A.1    Bachet, J.B.2    Boige, V.3    Cayre, A.4    Le Corre, D.5    Buc, E.6
  • 10
    • 41549167668 scopus 로고    scopus 로고
    • A randomised phase III study on capecitabine, oxaliplatin and bevacizumab with or without cetuximab in first-line advanced colorectal cancer, the CAIRO2 study of the Dutch Colorectal Cancer Group (DCCG)
    • An interim analysis of toxicity
    • Tol J, Koopman M, Rodenburg CJ, Cats A, Creemers GJ, Schrama JG, et al. A randomised phase III study on capecitabine, oxaliplatin and bevacizumab with or without cetuximab in first-line advanced colorectal cancer, the CAIRO2 study of the Dutch Colorectal Cancer Group (DCCG). An interim analysis of toxicity. Ann Oncol 2008;19:734-38.
    • (2008) Ann Oncol , vol.19 , pp. 734-738
    • Tol, J.1    Koopman, M.2    Rodenburg, C.J.3    Cats, A.4    Creemers, G.J.5    Schrama, J.G.6
  • 11
    • 65349189958 scopus 로고    scopus 로고
    • American Society of Clinical Oncology provisional clinical opinion: Testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy
    • Allegra CJ, Jessup JM, Somerfield MR, Hamilton SR, Hammond EH, Hayes DF, et al. American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy. J Clin Oncol 2009;27:2091-96.
    • (2009) J Clin Oncol , vol.27 , pp. 2091-2096
    • Allegra, C.J.1    Jessup, J.M.2    Somerfield, M.R.3    Hamilton, S.R.4    Hammond, E.H.5    Hayes, D.F.6
  • 12
    • 78049341541 scopus 로고    scopus 로고
    • Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab
    • De Roock W, Jonker DJ, Di Nicolantonio F, Sartore-Bianchi A, Tu D, Siena S, et al. Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab. JAMA 2010;304:1812-20.
    • (2010) JAMA , vol.304 , pp. 1812-1820
    • De Roock, W.1    Jonker, D.J.2    Di Nicolantonio, F.3    Sartore-Bianchi, A.4    Tu, D.5    Siena, S.6
  • 13
    • 84867117207 scopus 로고    scopus 로고
    • Association of KRAS G13D tumor mutations with outcome in patients with metastatic colorectal cancer treated with firstline chemotherapy with or without cetuximab
    • Tejpar S, Celik I, Schlichting M, Sartorius U, Bokemeyer C, Van Cutsem E. Association of KRAS G13D tumor mutations with outcome in patients with metastatic colorectal cancer treated with firstline chemotherapy with or without cetuximab. J Clin Oncol 2012;30:3570-77.
    • (2012) J Clin Oncol , vol.30 , pp. 3570-3577
    • Tejpar, S.1    Celik, I.2    Schlichting, M.3    Sartorius, U.4    Bokemeyer, C.5    Van Cutsem, E.6
  • 14
    • 33747030845 scopus 로고    scopus 로고
    • Protein biomarker discovery and validation: The long and uncertain path to clinical utility
    • Rifai N, Gillette MA, Carr S. Protein biomarker discovery and validation: the long and uncertain path to clinical utility. Nat Biotechnol 2006;24:971-83.
    • (2006) Nat Biotechnol , vol.24 , pp. 971-983
    • Rifai, N.1    Gillette, M.A.2    Carr, S.3
  • 15
    • 65249161129 scopus 로고    scopus 로고
    • Pathwaybased biomarker search by high-throughput proteomics profiling of secretomes
    • Lawlor K, Nazarian A, Lacomis L, Tempst P, Villanueva J. Pathwaybased biomarker search by high-throughput proteomics profiling of secretomes. Proteome Res 2009;8:1489-03.
    • (2009) Proteome Res , vol.8 , pp. 1489-1503
    • Lawlor, K.1    Nazarian, A.2    Lacomis, L.3    Tempst, P.4    Villanueva, J.5
  • 17
    • 67049172121 scopus 로고    scopus 로고
    • Secretome-based proteomic profiling of Ras-transformedMDCK cells reveals extracellular modulators of epithelial-mesenchymal transition
    • Mathias RA, Wang B, Ji H, Kapp EA, Moritz RL, Zhu HJ, Simpson RJ. Secretome-based proteomic profiling of Ras-transformedMDCK cells reveals extracellular modulators of epithelial-mesenchymal transition. J Proteome Res 2009;8:2827-37.
    • (2009) J Proteome Res , vol.8 , pp. 2827-2837
    • Mathias, R.A.1    Wang, B.2    Ji, H.3    Kapp, E.A.4    Moritz, R.L.5    Zhu, H.J.6    Simpson, R.J.7
  • 18
    • 84860522941 scopus 로고    scopus 로고
    • Proximal fluid proteome profiling of mouse colon tumors reveals biomarkers for early diagnosis of human colorectal cancer
    • Fijneman RJ, de Wit M, Pourghiasian M, Piersma SR, Pham TV, Warmoes MO, et al. Proximal fluid proteome profiling of mouse colon tumors reveals biomarkers for early diagnosis of human colorectal cancer. Clin Cancer Res 2012;18:2613-24.
    • (2012) Clin Cancer Res , vol.18 , pp. 2613-2624
    • Fijneman, R.J.1    De Wit, M.2    Pourghiasian, M.3    Piersma, S.R.4    Pham, T.V.5    Warmoes, M.O.6
  • 19
  • 20
    • 58549095879 scopus 로고    scopus 로고
    • Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses
    • Di Nicolantonio F, Arena S, Gallicchio M, Zecchin D, Martini M, Flonta SE, et al. Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses. Proc Natl Acad Sci U S A 2008;105:20864-69.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 20864-20869
    • Di Nicolantonio, F.1    Arena, S.2    Gallicchio, M.3    Zecchin, D.4    Martini, M.5    Flonta, S.E.6
  • 21
    • 84888289455 scopus 로고    scopus 로고
    • An effect size filter improves the reproducibility in spectral counting-based comparative proteomics
    • Gregori J, Villarreal L, Sáanchez A, Baselga J, Villanueva J. An effect size filter improves the reproducibility in spectral counting-based comparative proteomics. J Proteomics 2013;95:55-65.
    • (2013) J Proteomics , vol.95 , pp. 55-65
    • Gregori, J.1    Villarreal, L.2    Sáanchez, A.3    Baselga, J.4    Villanueva, J.5
  • 22
    • 84859168799 scopus 로고    scopus 로고
    • Oncogenic KRAS impairs EGFR antibodies' efficiency by C/ EBPb-dependent suppression of EGFR expression
    • Derer S, Berger S, Schlaeth M, Schneider-Merck T, Klausz K, Lohse S, et al. Oncogenic KRAS impairs EGFR antibodies' efficiency by C/ EBPb-dependent suppression of EGFR expression. Neoplasia 2012;14:190-205.
    • (2012) Neoplasia , vol.14 , pp. 190-205
    • Derer, S.1    Berger, S.2    Schlaeth, M.3    Schneider-Merck, T.4    Klausz, K.5    Lohse, S.6
  • 23
    • 58849089529 scopus 로고    scopus 로고
    • Mechanisms of regulated unconventional protein secretion
    • Nickel W, Rabouille C. Mechanisms of regulated unconventional protein secretion. Nat Rev Mol Cell Biol 2009;10:148-55.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 148-155
    • Nickel, W.1    Rabouille, C.2
  • 24
    • 84875444552 scopus 로고    scopus 로고
    • Impact of the 3D microenvironment on phenotype, gene expression, and EGFR inhibition of colorectal cancer cell lines
    • Luca AC, Mersch S, Deenen R, Schmidt S, Messner I, Sch €afer KL, et al. Impact of the 3D microenvironment on phenotype, gene expression, and EGFR inhibition of colorectal cancer cell lines. PLoS ONE 2013;8: e59689
    • (2013) PLoS ONE , vol.8 , pp. e59689
    • Luca, A.C.1    Mersch, S.2    Deenen, R.3    Schmidt, S.4    Messner, I.5    Schafer, K.L.6
  • 25
    • 77950863856 scopus 로고    scopus 로고
    • Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery
    • Fang DD, Kim YJ, Lee CN, Aggarwal S, McKinnon K, Mesmer D, et al. Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery. Br J Cancer 2010;102:1265-75.
    • (2010) Br J Cancer , vol.102 , pp. 1265-1275
    • Fang, D.D.1    Kim, Y.J.2    Lee, C.N.3    Aggarwal, S.4    McKinnon, K.5    Mesmer, D.6
  • 26
    • 79955939294 scopus 로고    scopus 로고
    • Proteome of human colon cancer stem cells: A comparative analysis
    • Zou J, Yu XF, Bao ZJ, Dong J. Proteome of human colon cancer stem cells: a comparative analysis. World J Gastroenterol 2011;17:1276-85.
    • (2011) World J Gastroenterol , vol.17 , pp. 1276-1285
    • Zou, J.1    Yu, X.F.2    Bao, Z.J.3    Dong, J.4
  • 27
    • 77949887855 scopus 로고    scopus 로고
    • Pharmacogenomic and pharmacoproteomic studies of cetuximab in metastatic colorectal cancer: Biomarker analysis of a phase I dose-escalation study
    • Tabernero J, Cervantes A, Rivera F, Martinelli E, Rojo F, von Heydebreck A, et al. Pharmacogenomic and pharmacoproteomic studies of cetuximab in metastatic colorectal cancer: biomarker analysis of a phase I dose-escalation study. J Clin Oncol 2010;28:1181-89.
    • (2010) J Clin Oncol , vol.28 , pp. 1181-1189
    • Tabernero, J.1    Cervantes, A.2    Rivera, F.3    Martinelli, E.4    Rojo, F.5    Von Heydebreck, A.6
  • 28
    • 84878724168 scopus 로고    scopus 로고
    • In-depth characterization of the secretome of colorectal cancer metastatic cells identifies key proteins in cell adhesion, migration, and invasion
    • Barderas R, Mendes M, Torres S, Bartolomée RA, Lóopez-Lucendo M, Villar-Váazquez R, et al. In-depth characterization of the secretome of colorectal cancer metastatic cells identifies key proteins in cell adhesion, migration, and invasion. Mol Cell Proteomics 2013;12:1602-20.
    • (2013) Mol Cell Proteomics , vol.12 , pp. 1602-1620
    • Barderas, R.1    Mendes, M.2    Torres, S.3    Bartolomée, R.A.4    Lóopez-Lucendo, M.5    Villar-Váazquez, R.6
  • 29
    • 84867887350 scopus 로고    scopus 로고
    • Deconstructing the third dimension-how 3D culture microenvironments alter cellular cues
    • Baker BM, Chen CS. Deconstructing the third dimension-how 3D culture microenvironments alter cellular cues. J Cell Science 2012;125:3015-24.
    • (2012) J Cell Science , vol.125 , pp. 3015-3024
    • Baker, B.M.1    Chen, C.S.2
  • 32
    • 57049103401 scopus 로고    scopus 로고
    • Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
    • Skog J, W Urdinger T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol 2008;10:1470-76.
    • (2008) Nat Cell Biol , vol.10 , pp. 1470-1476
    • Skog, J.1    Urdinger T, W.2    Van Rijn, S.3    Meijer, D.H.4    Gainche, L.5    Sena-Esteves, M.6
  • 33
    • 43049139913 scopus 로고    scopus 로고
    • Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells
    • Al-Nedawi K, Meehan B, Micallef J, Lhotak V, May L, Guha A, Rak J. Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells. Nat Cell Biol 2008;10:619-24.
    • (2008) Nat Cell Biol , vol.10 , pp. 619-624
    • Al-Nedawi, K.1    Meehan, B.2    Micallef, J.3    Lhotak, V.4    May, L.5    Guha, A.6    Rak, J.7
  • 34
    • 30544439417 scopus 로고    scopus 로고
    • Correlation between the response to cetuximab alone or in combination with irinotecan and the activated/phosphorylated epidermal growth factor receptor in metastatic colorectal cancer
    • Personeni N, Hendlisz A, Gallez J, Galdon M, Larsimont D, Vanlaethem J, et al. Correlation between the response to cetuximab alone or in combination with irinotecan and the activated/phosphorylated epidermal growth factor receptor in metastatic colorectal cancer. Semin Oncol 2005;32:59-62.
    • (2005) Semin Oncol , vol.32 , pp. 59-62
    • Personeni, N.1    Hendlisz, A.2    Gallez, J.3    Galdon, M.4    Larsimont, D.5    Vanlaethem, J.6


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