Distinct pathways of cholesterol biosynthesis impact on insulin secretion

Journal of Endocrinology

Volumn 224, Issue 1, 2015, Pages 75-84

  Zúñiga Hertz, Juan P ^a,b   Rebelato, Eduardo ^a   Kassan, Adam ^b   Khalifa, Abdelrahman M ^c   Ali, Sameh S ^b,c   Patel, Hemal H ^b   Abdulkader, Fernando ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b University of California at San Diego   (United States)

^c ZEWAIL CITY OF SCIENCE AND TECHNOLOGY   (Egypt)

Author keywords

Cholesterol; Isoprenylation; Membrane; Secretion

Indexed keywords

CHOLESTEROL; GERANYLGERANYL PYROPHOSPHATE; ISOPRENOID; SIMVASTATIN; FUSED HETEROCYCLIC RINGS; GLUCOSE; HYPOCHOLESTEROLEMIC AGENT; INSULIN; ISOPRENOID PHOSPHATE; TRICARBOXYLIC ACID; ZARAGOZIC ACID A;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CELL MEMBRANE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENZYME INHIBITION; INSULIN RELEASE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN PRENYLATION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECTS; MEMBRANE FLUIDITY; METABOLISM; PHYSIOLOGY; SECRETION (PROCESS);

ANIMALS; ANTICHOLESTEREMIC AGENTS; BICYCLO COMPOUNDS, HETEROCYCLIC; CELLS, CULTURED; CHOLESTEROL; GLUCOSE; INSULIN; MEMBRANE FLUIDITY; MEMBRANE MICRODOMAINS; METABOLIC NETWORKS AND PATHWAYS; MICE; POLYISOPRENYL PHOSPHATES; SIMVASTATIN; TRICARBOXYLIC ACIDS;

EID: 84919608736     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-14-0348     Document Type: Article

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