Apelin-13 and APJ in paraventricular nucleus contribute to hypertension via sympathetic activation and vasopressin release in spontaneously hypertensive rats

Acta Physiologica

Volumn 212, Issue 1, 2014, Pages 17-27

  Zhang, F ^a   Sun, H J ^a   Xiong, X Q ^a   Chen, Q ^a   Li, Y H ^a   Kang, Y M ^b   Wang, J J ^a   Gao, X Y ^a   Zhu, G Q ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Apelin; Hypertension; N methyl D aspartate receptor; Sympathetic nerve activity; Vasopressin

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; APELIN; APELIN 13; ARGIPRESSIN; ARGIPRESSIN[1 (3,3 CYCLOPENTAMETHYLENE 3 MERCAPTOPROPIONIC ACID) 2 (O METHYLTYROSINE)]; ATRIAL NATRIURETIC FACTOR; F 13A; HEXAMETHONIUM; LOSARTAN; MESSENGER RNA; MYOSIN HEAVY CHAIN BETA; NEUROPEPTIDE; NORADRENALIN; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG; VASOPRESSIN; APELIN-13 PEPTIDE; APLNR PROTEIN, RAT; G PROTEIN COUPLED RECEPTOR; SIGNAL PEPTIDE;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART MUSCLE; HEART VENTRICLE HYPERTROPHY; HYPERTENSION; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; KIDNEY NERVE; MALE; MEAN ARTERIAL PRESSURE; MICROINJECTION; NONHUMAN; NORADRENALIN BLOOD LEVEL; OSMOTIC MINIPUMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; RENAL SYMPATHETIC NERVE ACTIVITY; SPONTANEOUSLY HYPERTENSIVE RAT; SYMPATHETIC NERVE; SYMPATHETIC TONE; VASOPRESSIN RELEASE; WESTERN BLOTTING; WISTAR KYOTO RAT; ADRENERGIC SYSTEM; ANIMAL; ELECTROPHYSIOLOGY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETION (PROCESS);

ANIMALS; ARGININE VASOPRESSIN; BLOTTING, WESTERN; ELECTROPHYSIOLOGY; HYPERTENSION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SYMPATHETIC NERVOUS SYSTEM;

EID: 84919595423     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/apha.12342     Document Type: Article

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