Superoxide anions involved in sympathoexcitation and pressor effects of salusin-β in paraventricular nucleus in hypertensive rats

Acta Physiologica

Volumn 210, Issue 3, 2014, Pages 534-545

  Sun, H J ^a   Zhang, L L ^a   Fan, Z D ^b   Chen, D ^a   Zhang, L ^a   Gao, X Y ^a   Kang, Y M ^c   Zhu, G Q ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b CHILDREN S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^c MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Hypertension; Salusin; Superoxide anions; Sympathetic nerve activity; Vasopressin

Indexed keywords

3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; ANGIOTENSIN[1-7][7 DEXTRO ALANINE]; APOCYNIN; ARGIPRESSIN; HYPERTENSIVE FACTOR; LOSARTAN; MACROGOL; MESSENGER RNA; MRGA1 PROTEIN; N(G) NITROARGININE METHYL ESTER; NITRATE REDUCTASE [NAD(P)H]; PROTEIN; PROTEIN KINASE C; SALUSIN BETA; SUPEROXIDE; SUPEROXIDE DISMUTASE; TEMPOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HEART RATE; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; MOLECULAR MECHANICS; NERVE EXCITABILITY; NONHUMAN; PARAVENTRICULAR THALAMIC NUCLEUS; PRESSOR RESPONSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RENOVASCULAR HYPERTENSION; SHAM PROCEDURE; SYMPATHETIC NERVE;

HYPERTENSION; SALUSIN; SUPEROXIDE ANIONS; SYMPATHETIC NERVE ACTIVITY; VASOPRESSIN;

ANIMALS; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYPERTENSION; HYPERTENSION, RENOVASCULAR; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; SUPEROXIDES; SYMPATHETIC NERVOUS SYSTEM;

EID: 84893713376     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/apha.12188     Document Type: Article

References (39)

1. Beckman, J.S., Minor, R.L. Jr, White, C.W., Repine, J.E., Rosen, G.M. & Freeman, B.A. 1988. Superoxide dismutase and catalase conjugated to polyethylene glycol increases endothelial enzyme activity and oxidant resistance. J Biol Chem 263, 6884-6892.
2. Burmeister, M.A., Young, C.N., Braga, V.A., Butler, S.D., Sharma, R.V. & Davisson, R.L. 2011. In vivo bioluminescence imaging reveals redox-regulated activator protein-1 activation in paraventricular nucleus of mice with renovascular hypertension. Hypertension 57, 289-297.
3. Cai, H., Griendling, K.K. & Harrison, D.G. 2003. The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. Trends Pharmacol Sci 24, 471-478.
4. Chang, M.Y., Huang, D.Y., Ho, F.M., Huang, K.C. & Lin, W.W. 2012. PKC-dependent human monocyte adhesion requires AMPK and Syk activation. PLoS ONE 7, e40999.
5. 1 receptors in paraventricular nucleus contribute to sympathetic activation and enhanced cardiac sympathetic afferent reflex in renovascular hypertensive rats. Exp Physiol 96, 94-103.
6. Chen, W.W., Sun, H.J., Zhang, F., Zhou, Y.B., Xiong, X.Q., Wang, J.J. & Zhu, G.Q. 2013. Salusin-β in paraventricular nucleus increases blood pressure and sympathetic outflow via vasopressin in hypertensive rats. Cardiovasc Res 98, 344-351.
7. Cui, B.P., Li, P., Sun, H.J., Ding, L., Zhou, Y.B., Wang, J.J., Kang, Y.M. & Zhu, G.Q. 2013. Ionotropic glutamate receptors in paraventricular nucleus mediate adipose afferent reflex and regulate sympathetic outflow in rats. Acta Physiol (Oxf) 209, 45-54.
8. De, M.E., Baldassari, F., Bononi, A., Wieckowski, M.R. & Pinton, P. 2013. Oxidative stress in cardiovascular diseases and obesity: role of p66Shc and protein kinase C. Oxid Med Cell Longev 2013, 564961.
9. Fan, Z.D., Zhang, L., Shi, Z., Gan, X.B., Gao, X.Y. & Zhu, G.Q. 2012. Artificial microRNA interference targeting AT1a receptors in paraventricular nucleus attenuates hypertension in rats. Gene Ther 19, 810-817.
10. Gomez, R.E., Cannata, M.A., Milner, T.A., Anwar, M., Reis, D.J. & Ruggiero, D.A. 1993. Vasopressinergic mechanisms in the nucleus reticularis lateralis in blood pressure control. Brain Res 604, 90-105.
11. Grisk, O. 2011. Antihypertensive effects of ACE2 in the paraventricular nucleus: a consequence of reduced neuroinflammation? Cardiovasc Res 92, 365-366.
12. Han, Y., Fan, Z.D., Yuan, N., Xie, G.Q., Gao, J., De, W., Gao, X.Y. & Zhu, G.Q. 2011a. Superoxide anions in paraventricular nucleus mediate the enhanced cardiac sympathetic afferent reflex and sympathetic activity in renovascular hypertensive rats. J Appl Physiol 110, 646-652.
13. Han, Y., Yuan, N., Zhang, S.J., Gao, J., Shi, Z., Zhou, Y.B., Gao, X.Y. & Zhu, G.Q. 2011b. c-Src in paraventricular nucleus modulates sympathetic activity and cardiac sympathetic afferent reflex in renovascular hypertensive rats. Pflugers Arch 461, 437-446.
14. Izumiyama, H., Tanaka, H., Egi, K., Sunamori, M., Hirata, Y. & Shichiri, M. 2005. Synthetic salusins as cardiac depressors in rat. Hypertension 45, 419-425.
15. Ji, L., Chauhan, A. & Chauhan, V. 2012. Reduced activity of protein kinase C in the frontal cortex of subjects with regressive autism: relationship with developmental abnormalities. Int J Biol Sci 8, 1075-1084.
16. Kc, P., Balan, K.V., Tjoe, S.S., Martin, R.J., Lamanna, J.C., Haxhiu, M.A. & Dick, T.E. 2010. Increased vasopressin transmission from the paraventricular nucleus to the rostral medulla augments cardiorespiratory outflow in chronic intermittent hypoxia-conditioned rats. J Physiol 588, 725-740.
17. Koya, T., Miyazaki, T., Watanabe, T., Shichiri, M., Atsumi, T., Kim-Kaneyama, J.R. & Miyazaki, A. 2012. Salusin-β accelerates inflammatory responses in vascular endothelial cells via NF-kappaB signaling in LDL receptor-deficient mice in vivo and HUVECs in vitro. Am J Physiol Heart Circ Physiol 303, H96-H105.
18. Noguera, I., Medina, P., Segarra, G., Martinez, M.C., Aldasoro, M., Vila, J.M. & Lluch, S. 1997. Potentiation by vasopressin of adrenergic vasoconstriction in the rat isolated mesenteric artery. Br J Pharmacol 122, 431-438.
19. Persson, P.B. & Henriksson, J. 2011. Editorial. Acta Physiol 203, 403-407.
20. Pyner, S. 2009. Neurochemistry of the paraventricular nucleus of the hypothalamus: implications for cardiovascular regulation. J Chem Neuroanat 38, 197-208.
21. Rosc-Schluter, B.I., Hauselmann, S.P., Lorenz, V., Mochizuki, M., Facciotti, F., Pfister, O. & Kuster, G.M. 2012. NOX2-derived reactive oxygen species are crucial for CD29-induced pro-survival signalling in cardiomyocytes. Cardiovasc Res 93, 454-462.
22. Saito, T., Dayanithi, G., Saito, J., Onaka, T., Urabe, T., Watanabe, T.X., Hashimoto, H., Yokoyama, T., Fujihara, H., Yokota, A., Nishizawa, S., Hirata, Y. & Ueta, Y. 2008. Chronic osmotic stimuli increase salusin-beta-like immunoreactivity in the rat hypothalamo-neurohypophyseal system: possible involvement of salusin-beta on [Ca2+]i increase and neurohypophyseal hormone release from the axon terminals. J Neuroendocrinol 20, 207-219.
23. Shi, Z., Chen, A.D., Xu, Y., Chen, Q., Gao, X.Y., Wang, W. & Zhu, G.Q. 2009. Long-term administration of tempol attenuates postinfarct ventricular dysfunction and sympathetic activity in rats. Pflugers Arch 458, 247-257.
24. Shi, Z., Gan, X.B., Fan, Z.D., Zhang, F., Zhou, Y.B., Gao, X.Y., De, W. & Zhu, G.Q. 2011. Inflammatory cytokines in paraventricular nucleus modulate sympathetic activity and cardiac sympathetic afferent reflex in rats. Acta Physiol (Oxf) 203, 289-297.
25. Shichiri, M., Ishimaru, S., Ota, T., Nishikawa, T., Isogai, T. & Hirata, Y. 2003. Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities. Nat Med 9, 1166-1172.
26. Sun, H.J., Li, P., Chen, W.W., Xiong, X.Q. & Han, Y. 2012. Angiotensin II and angiotensin-(1-7) in paraventricular nucleus modulate cardiac sympathetic afferent reflex in renovascular hypertensive rats. PLoS ONE 7, e52557.
27. Suzuki, N., Shichiri, M., Akashi, T., Sato, K., Sakurada, M., Hirono, Y., Yoshimoto, T., Koyama, T. & Hirata, Y. 2007. Systemic distribution of salusin expression in the rat. Hypertens Res 30, 1255-1262.
28. Takeda, K., Nakata, T., Takesako, T., Itoh, H., Hirata, M., Kawasaki, S., Hayashi, J., Oguro, M., Sasaki, S. & Nakagawa, M. 1991. Sympathetic inhibition and attenuation of spontaneous hypertension by PVN lesions in rats. Brain Res 543, 296-300.
29. Takenoya, F., Hori, T., Kageyama, H., Funahashi, H., Takeuchi, M., Kitamura, Y., Shichiri, M. & Shioda, S. 2005. Coexistence of salusin and vasopressin in the rat hypothalamo-hypophyseal system. Neurosci Lett 385, 110-113.
30. Tanaka, C. & Saito, N. 1992. Localization of subspecies of protein kinase C in the mammalian central nervous system. Neurochem Int 21, 499-512.
31. Triantafyllou, A., Bikineyeva, A., Dikalova, A., Nazarewicz, R., Lerakis, S. & Dikalov, S. 2011. Anti-inflammatory activity of Chios mastic gum is associated with inhibition of TNF-alpha induced oxidative stress. Nutr J 10, 64.
32. Vaneckova, I., Vokurkova, M., Rauchova, H., Dobesova, Z., Pechanova, O., Kunes, J., Vorlicek, J. & Zicha, J. 2013. Chronic antioxidant therapy lowers blood pressure in adult but not in young Dahl salt hypertensive rats: the role of sympathetic nervous system. Acta Physiol (Oxf) 208, 340-349.
33. Vega, C., Moreno-Carranza, B., Zamorano, M., Quintanar-Stephano, A., Mendez, I., Thebault, S., de la Martinez, E.G. & Clapp, C. 2010. Prolactin promotes oxytocin and vasopressin release by activating neuronal nitric oxide synthase in the supraoptic and paraventricular nuclei. Am J Physiol Regul Integr Comp Physiol 299, R1701-R1708.
34. Wang, Z., Takahashi, T., Saito, Y., Nagasaki, H., Ly, N.K., Nothacker, H.P., Reinscheid, R.K., Yang, J., Chang, J.K., Shichiri, M. & Civelli, O. 2006. Salusin beta is a surrogate ligand of the mas-like G protein-coupled receptor MrgA1. Eur J Pharmacol 539, 145-150.
35. Xiong, X.Q., Chen, W.W., Han, Y., Zhou, Y.B., Zhang, F., Gao, X.Y. & Zhu, G.Q. 2012. Enhanced adipose afferent reflex contributes to sympathetic activation in diet-induced obesity hypertension. Hypertension 60, 1280-1286.
36. Yamada, J., Yoshimura, S., Yamakawa, H., Sawada, M., Nakagawa, M., Hara, S., Kaku, Y., Iwama, T., Naganawa, T., Banno, Y., Nakashima, S. & Sakai, N. 2003. Cell permeable ROS scavengers, Tiron and Tempol, rescue PC12 cell death caused by pyrogallol or hypoxia/reoxygenation. Neurosci Res 45, 1-8.
37. Yang, Z. & Coote, J.H. 2003. The influence of vasopressin on tonic activity of cardiovascular neurones in the ventrolateral medulla of the hypertensive rat. Auton Neurosci 104, 83-87.
38. Yang, Z., Bertram, D. & Coote, J.H. 2001. The role of glutamate and vasopressin in the excitation of RVL neurones by paraventricular neurones. Brain Res 908, 99-103.
39. Yu, F., Zhao, J., Yang, J., Gen, B., Wang, S., Feng, X., Tang, C. & Chang, L. 2004. Salusins promote cardiomyocyte growth but does not affect cardiac function in rats. Regul Pept 122, 191-197.