Blocking of the interaction between Wnt proteins and their co-receptors contributes to the anti-tumor effects of adenovirus-mediated DKK3 in glioblastoma

Cancer Letters

Volumn 356, Issue 2, 2015, Pages 496-505

  Hara, Keijiro ^a   Kageji, Teruyoshi ^a   Mizobuchi, Yoshifumi ^a   Kitazato, Keiko T ^a   Okazaki, Toshiyuki ^a   Fujihara, Toshitaka ^a   Nakajima, Kohei ^a   Mure, Hideo ^a   Kuwayama, Kazuyuki ^a   Hara, Tomoyo ^b   Nagahiro, Shinji ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

DKK3; Glioblastoma; LRP6; Wnt3a; Wnt5a

Indexed keywords

ADENOVIRUS VECTOR; ANTINEOPLASTIC AGENT; DKK3 PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; PROTEIN ROR2; RECEPTOR PROTEIN; UNCLASSIFIED DRUG; WNT3A PROTEIN; WNT5A PROTEIN; DKK3 PROTEIN, HUMAN; LRP6 PROTEIN, HUMAN; MESSENGER RNA; ONCOPROTEIN; RECEPTOR TYROSINE KINASE LIKE ORPHAN RECEPTOR; ROR2 PROTEIN, HUMAN; SIGNAL PEPTIDE; WNT PROTEIN; WNT3A PROTEIN, HUMAN; WNT5A PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ATTENUATION; CANCER CELL CULTURE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; GLIOBLASTOMA; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UPREGULATION; VIRAL GENE DELIVERY SYSTEM; ADENOVIRIDAE; ADMINISTRATION AND DOSAGE; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; DRUG SCREENING; ENZYME IMMUNOASSAY; FLOW CYTOMETRY; GENE VECTOR; GENETICS; IMMUNOPRECIPITATION; METABOLISM; NUDE MOUSE; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE; WESTERN BLOTTING;

ADENOVIRIDAE;

ADENOVIRIDAE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; FLOW CYTOMETRY; GENETIC VECTORS; GLIOBLASTOMA; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-6; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; PROTO-ONCOGENE PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR TYROSINE KINASE-LIKE ORPHAN RECEPTORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED; WNT PROTEINS; WNT3A PROTEIN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84919491383     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.09.045     Document Type: Article

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