Differential complement activation pathways promote C3b deposition on native and acetylated LDL thereby inducing lipoprotein binding to the complement receptor 1

Journal of Biological Chemistry

Volumn 289, Issue 51, 2014, Pages 35421-35430

  Klop, Boudewijn ^a   Van Der Pol, Pieter ^b   Van Bruggen, Robin ^c   Wang, Yanan ^b   De Vries, Marijke A ^a   Van Santen, Selvetta ^a   O'Flynn, Joseph ^b   Van De Geijn, Gert Jan M ^a   Njo, Tjin L ^a   Janssen, Hans W ^a   De Man, Peter ^a   Wouter Jukema, J ^b   Rabelink, Ton J ^b   Rensen, Patrick C N ^b   Van Kooten, Cees ^b   Cabezas, Manuel Castro ^a  

^a SINT FRANCISCUS GASTHUIS   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c SANQUIN RESEARCH   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; LIPIDS; LIPOPROTEINS;

APOLIPOPROTEIN B; CELLULAR DISTRIBUTIONS; CHINESE HAMSTERS; CLASSICAL PATHWAY; COMPLEMENT ACTIVATIONS; HUMAN SERUM; LDL RECEPTORS; UP-REGULATION;

BINS;

COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C3B RECEPTOR; EDETIC ACID; EGTAZIC ACID; IMMUNOGLOBULIN M; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MANNOSE BINDING LECTIN; PROPERDIN; ACETYL-LDL; APOLIPOPROTEIN B; LIPOPOLYSACCHARIDE; OPSONIN; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; CHO CELL LINE; COMPLEMENT ACTIVATION; COMPLEMENT ALTERNATIVE PATHWAY; COMPLEMENT CLASSICAL PATHWAY; COMPLEMENT DEPOSITION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EX VIVO STUDY; FLOW CYTOMETRY; GENETIC TRANSFECTION; IN VITRO STUDY; LEUKOCYTE; NONHUMAN; OPSONIZATION; PROTEIN ACETYLATION; PROTEIN BINDING; PROTEIN LOCALIZATION; RECEPTOR BINDING; UPREGULATION; ANIMAL; CELL CULTURE; CRICETULUS; CYTOLOGY; DRUG EFFECTS; GENETICS; HAMSTER; HUMAN; METABOLISM;

CRICETULUS GRISEUS;

ANIMALS; APOLIPOPROTEINS B; CELLS, CULTURED; CHO CELLS; COMPLEMENT ACTIVATION; COMPLEMENT C1Q; COMPLEMENT C3B; COMPLEMENT PATHWAY, ALTERNATIVE; COMPLEMENT PATHWAY, CLASSICAL; CRICETINAE; CRICETULUS; EDETIC ACID; FLOW CYTOMETRY; HUMANS; IMMUNOGLOBULIN M; LEUKOCYTES; LIPOPOLYSACCHARIDES; LIPOPROTEINS, LDL; OPSONIN PROTEINS; PROPERDIN; PROTEIN BINDING; RECEPTORS, COMPLEMENT 3B;

EID: 84919472904     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.573840     Document Type: Article

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