L-Ficolin binding and lectin pathway activation by acetylated low-density lipoprotein

Clinical and Experimental Immunology

Volumn 151, Issue 2, 2008, Pages 275-283

  Faro, J ^a   Chen, Y ^a   Jhaveri, P ^a   Oza, P ^a   Spear, G T ^a   Lint, T F ^a   Gewurz, H ^a  

^a RUSH MEDICAL COLLEGE   (United States)

Author keywords

L ficolin; Lectin pathway; MASP 2

Indexed keywords

ACETYL LOW DENSITY LIPOPROTEIN; ALBUMIN; ALPHA 2 MACROGLOBULIN; CALCIUM; COMPLEMENT COMPONENT C4; EDETIC ACID; ENZYME PRECURSOR; FICOLIN; LECTIN; MANNAN BINDING LECTIN; MBL ASSOCIATED SERINE PROTEASE 2; SEPHAROSE; SERINE PROTEINASE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; ELUTION; ENZYME ACTIVATION; ENZYME PURIFICATION; HUMAN; LIGAND BINDING; NORMAL HUMAN; PLASMA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN ISOLATION; PROTEIN LIPID INTERACTION; PROTEIN PROTEIN INTERACTION;

ACETYLATION; COMPLEMENT PATHWAY, MANNOSE-BINDING LECTIN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; ENZYME PRECURSORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; LECTINS; LIGANDS; LIPOPROTEINS, LDL; MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES;

EID: 37849046576     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2007.03538.x     Document Type: Article

References (35)

1. Soothill JF, Harvey BA. Defective opsonization. A common immunity deficiency. Arch Dis Child 1976 51 : 91 9.
2. Matsushita M, Fujita T. Activation of the classical complement pathway by mannose-binding protein in association with a novel C1s-like serine protease. J Exp Med 1992 176 : 1497 502.
3. Thiel S, Vorup-Jensen T, Stover CM et al. A second serine protease associated with mannan-binding lectin that activates complement. Nature 1997 386 : 506 10.
4. Dahl MR, Thiel S, Matsushita M et al. MASP-3 and its association with distinct complexes of the mannan-binding lectin complement activation pathway. Immunity 2001 15 : 127 35.
5. Le Y, Tan SM, Lee SH, Kon OL, Lu J. Purification and binding properties of a human ficolin-like protein. J Immunol Methods 1997 204 : 43 9.
6. Tsujimura M, Ishida C, Sagara Y et al. Detection of serum thermolabile beta-2 macroglycoprotein (Hakata antigen) by enzyme-linked immunosorbent assay using polysaccharide produced by Aerococcus viridans. Clin Diagn Lab Immunol 2001 8 : 454 9.
7. Lu J, Teh C, Kishore U, Reid KB. Collectins and ficolins: sugar pattern recognition molecules of the mammalian innate immune system. Biochim Biophys Acta 2002 1572 : 387 400.
8. Ichijo H, Hellman U, Wernstedt C et al. Molecular cloning and characterization of ficolin, a multimeric protein with fibrinogen- and collagen-like domains. J Biol Chem 1993 268 : 14505 13.
9. Matsushita M, Endo Y, Taira S et al. A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin. J Biol Chem 1996 271 : 2448 54.
10. Le Y, Lee SH, Kon OL, Lu J. Human l-ficolin: plasma levels, sugar specificity, and assignment of its lectin activity to the fibrinogen-like (FBG) domain. FEBS Lett 1998 425 : 367 70.
11. Takahashi K, Ip WE, Michelow IC, Ezekowitz RA. The mannose-binding lectin: a prototypic pattern recognition molecule. Curr Opin Immunol 2006 18 : 16 23.
12. Harumiya S, Omori A, Sugiura T, Fukumoto Y, Tachikawa H, Fujimoto D. EBP-37, a new elastin-binding protein in human plasma: structural similarity to ficolins, transforming growth factor-beta 1-binding proteins. J Biochem (Tokyo) 1995 117 : 1029 35.
13. Edgar P, Stein P. Hormone binding site of corticosteroid binding globulin. Nat Struct Biol 1995 2 : 196 7.
14. Ma YG, Cho MY, Zhao M et al. Human mannose-binding lectin and l-ficolin function as specific pattern recognition proteins in the lectin activation pathway of complement. J Biol Chem 2004 279 : 25307 12.
15. Krarup A, Thiel S, Hansen A, Fujita T, Jensenius JC. L-Ficolin is a pattern recognition molecule specific for acetyl groups. J Biol Chem 2004 279 : 47513 19.
16. Matsushita M, Endo Y, Fujita T. Cutting edge: complement-activating complex of ficolin and mannose-binding lectin-associated serine protease. J Immunol 2000 164 : 2281 4.
17. Cseh S, Vera L, Matsushita M, Fujita T, Arlaud GJ, Thielens NM. Characterization of the interaction between l-ficolin/p35 and mannan-binding lectin-associated serine proteases-1 and -2. J Immunol 2002 169 : 5735 43.
18. Lynch NJ, Roscher S, Hartung T et al. L-Ficolin specifically binds to lipoteichoic acid, a cell wall constituent of Gram-positive bacteria, and activates the lectin pathway of complement. J Immunol 2004 172 : 1198 202.
19. Gregory LA, Thielens NM, Matsushita M et al. The X-ray structure of human mannan-binding lectin-associated protein 19 (MAp19) and its interaction site with mannan-binding lectin and l-ficolin. J Biol Chem 2004 279 : 29391 7.
20. Ohashi T, Erickson HP. Two oligomeric forms of plasma ficolin have differential lectin activity. J Biol Chem 1997 272 : 14220 6.
21. Brooks AS, Hammermueller J, DeLay JP, Hayes MA. Expression and secretion of ficolin beta by porcine neutrophils. Biochim Biophys Acta 2003 1624 : 36 45.
22. Matsushita M, Fujita T. Ficolins and the lectin complement pathway. Immunol Rev 2001 180 : 78 85.
23. Vorup-Jensen T, Petersen SV, Hansen AG et al. Distinct pathways of mannan-binding lectin (MBL)- and C1-complex autoactivation revealed by reconstitution of MBL with recombinant MBL-associated serine protease-2. J Immunol 2000 165 : 2093 100.
24. Rossi V, Cseh S, Bally I, Thielens NM, Jensenius JC, Arlaud GJ. Substrate specificities of recombinant mannan-binding lectin-associated serine proteases-1 and -2. J Biol Chem 2001 276 : 40880 7.
25. Hajela K, Kojima M, Ambrus G et al. The biological functions of MBL-associated serine proteases (MASPs). Immunobiology 2002 205 : 467 75.
26. Kilpatrick DC, Fujita T, Matsushita M. P35, an opsonic lectin of the ficolin family, in human blood from neonates, normal adults, and recurrent miscarriage patients. Immunol Lett 1999 67 : 109 12.
27. Moller-Kristensen M, Jensenius JC, Jensen L et al. Levels of mannan-binding lectin-associated serine protease-2 in healthy individuals. J Immunol Methods 2003 282 : 159 67.
28. Petersen SV, Thiel S, Jensenius JC. The mannan-binding lectin pathway of complement activation: biology and disease association. Mol Immunol 2001 38 : 133 49.
29. Hummelshoj T, Thielens NM, Madsen HO, Arlaud GJ, Sim RB, Garred P. Molecular organization of human ficolin-2. Mol Immunol 2007 44 : 401 11.
30. Matsushita M, Kuraya M, Hamasaki N, Tsujimura M, Shiraki H, Fujita T. Activation of the lectin complement pathway by h-ficolin (Hakata antigen). J Immunol 2002 168 : 3502 6.
31. Petersen SV, Thiel S, Jensen L, Steffensen R, Jensenius JC. An assay for the mannan-binding lectin pathway of complement activation. J Immunol Methods 2001 257 : 107 16.
32. Holmskov U, Thiel S, Jensenius JC. Collections and ficolins: humoral lectins of the innate immune defense. Annu Rev Immunol 2003 21 : 547 78.
33. Garlatti V, Belloy N, Martin L et al. Structural insights into the innate immune recognition specificities of l- and h-ficolins. EMBO J 2007 26 : 623 33.
34. Tan SM, Chung MC, Kon OL, Thiel S, Lee SH, Lu J. Improvements on the purification of mannan-binding lectin and demonstration of its Ca(2+)-independent association with a C1s-like serine protease. Biochem J 1996 319 : 329 32.
35. Aoyagi Y, Adderson EE, Min JG et al. Role of l-ficolin/mannose-binding lectin-associated serine protease complexes in the opsonophagocytosis of type III group B streptococci. J Immunol 2005 174 : 418 25.