S-allyl cysteine alleviates nonsteroidal anti-inflammatory drug-induced gastric mucosal damages by increasing cyclooxygenase-2 inhibition, heme oxygenase-1 induction, and histone deacetylation inhibition

Journal of Gastroenterology and Hepatology (Australia)

Volumn 29, Issue S4, 2014, Pages 80-92

  Park, Jong Min ^a   Han, Young Min ^a   Kangwan, Napapan ^a   Lee, Soo Yeon ^a   Jung, Mi Kyoung ^a   Kim, Eun Hee ^a   Hahm, Ki Baik ^a  

^a CHA University   (South Korea)

Author keywords

Anti inflammation; Anti oxidant; NSAIDs induced gastropathy; Prevention; S allyl cysteine

Indexed keywords

CYCLOOXYGENASE 2; HEME OXYGENASE 1; HISTONE DEACETYLASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOMETACIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN E2; REBAMIPIDE; S ALLYLCYSTEINE; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CYSTEINE; NONSTEROID ANTIINFLAMMATORY AGENT; S-ALLYLCYSTEINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL INFILTRATION; CELL PROTECTION; CLINICAL EVALUATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL GASTRIC ULCER; EXPERIMENTAL INFLAMMATION; FEMALE; GARLIC; HISTOPATHOLOGY; IN VITRO STUDY; LOW DRUG DOSE; MACROPHAGE; MEDIATOR RELEASE; MOUSE; MUCUS SECRETION; NICK END LABELING; NONHUMAN; PERIODIC ACID SCHIFF STAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STAINING; STOMACH MUCOSA INJURY; STOMACH PROTECTION; ULCER HEALING; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PATHOLOGY; STOMACH MUCOSA; STOMACH ULCER;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; CYCLOOXYGENASE 2; CYSTEINE; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GASTRIC MUCOSA; HEME OXYGENASE-1; HISTONE DEACETYLASES; IN VITRO TECHNIQUES; INDOMETHACIN; MICE, INBRED C57BL; STOMACH ULCER;

EID: 84919429532     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/jgh.12730     Document Type: Article

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