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Volumn 6, Issue , 2013, Pages

Sustained Elevation of Kynurenic Acid in the Cerebrospinal Fluid of Patients with Herpes Simplex Virus Type 1 Encephalitis

Author keywords

cognition; HSE; neurodegeneration; NMDA hypofunction; Tryptophan

Indexed keywords


EID: 84919402466     PISSN: None     EISSN: 11786469     Source Type: Journal    
DOI: 10.4137/IJTR.S13256     Document Type: Article
Times cited : (18)

References (69)
  • 2
    • 0035849323 scopus 로고    scopus 로고
    • Herpes simplex virus infections
    • Whitley R.J., Roizman B. Herpes simplex virus infections. Lancet. 2001; 357(9267): 1513–8.
    • (2001) Lancet , vol.357 , Issue.9267 , pp. 1513-1518
    • Whitley, R.J.1    Roizman, B.2
  • 3
    • 4344685826 scopus 로고    scopus 로고
    • Herpes simplex virus infections of the central nervous system: encephalitis and meningitis, including Mollaret's
    • Sul
    • Tyler K.L. Herpes simplex virus infections of the central nervous system: encephalitis and meningitis, including Mollaret's. Herpes. 2004; 11 Suppl 2: 57A–64A.
    • (2004) Herpes , vol.11 , Issue.2 , pp. 57A-64A
    • Tyler, K.L.1
  • 5
    • 15744387169 scopus 로고    scopus 로고
    • Herpes simplex encephalitis: children and adolescents
    • Whitley R.J., Kimberlin D.W. Herpes simplex encephalitis: children and adolescents. Semin Pediatr Infect Dis. 2005; 16(1): 17–23.
    • (2005) Semin Pediatr Infect Dis , vol.16 , Issue.1 , pp. 17-23
    • Whitley, R.J.1    Kimberlin, D.W.2
  • 6
    • 33747172270 scopus 로고    scopus 로고
    • Herpes simplex encephalitis: adolescents and adults
    • Whitley R.J. Herpes simplex encephalitis: adolescents and adults. Antiviral Res. 2006; 71(2-3): 141–8.
    • (2006) Antiviral Res , vol.71 , Issue.2-3 , pp. 141-148
    • Whitley, R.J.1
  • 8
    • 0023882653 scopus 로고
    • Herpes simplex virus encephalitis in children
    • Kohl S. Herpes simplex virus encephalitis in children. Pediatr Clin North Am. 1988; 35(3): 465–83.
    • (1988) Pediatr Clin North Am , vol.35 , Issue.3 , pp. 465-483
    • Kohl, S.1
  • 9
    • 0021145262 scopus 로고
    • Acyclovir versus vidarabine in herpes simplex encephalitis. Randomised multicentre study in consecutive Swedish patients
    • Sköldenberg B., Forsgren M., Alestig K. et al. Acyclovir versus vidarabine in herpes simplex encephalitis. Randomised multicentre study in consecutive Swedish patients. Lancet. 1984; 2(8405): 707–11.
    • (1984) Lancet , vol.2 , Issue.8405 , pp. 707-711
    • Sköldenberg, B.1    Forsgren, M.2    Alestig, K.3
  • 10
    • 0022645112 scopus 로고
    • Vidarabine versus acyclovir therapy in herpes simplex encephalitis
    • Whitley R.J., Alford C.A., Hirsch M.S. et al. Vidarabine versus acyclovir therapy in herpes simplex encephalitis. N Engl J Med. 1986; 314(3): 144–9.
    • (1986) N Engl J Med , vol.314 , Issue.3 , pp. 144-149
    • Whitley, R.J.1    Alford, C.A.2    Hirsch, M.S.3
  • 11
    • 0036680459 scopus 로고    scopus 로고
    • Outcome of and prognostic factors for herpes simplex encephalitis in adult patients: results of a multicenter study
    • Raschilas F., Wolff M., Delatour F. et al. Outcome of and prognostic factors for herpes simplex encephalitis in adult patients: results of a multicenter study. Clin Infect Dis. 2002; 35(3): 254–60.
    • (2002) Clin Infect Dis , vol.35 , Issue.3 , pp. 254-260
    • Raschilas, F.1    Wolff, M.2    Delatour, F.3
  • 12
    • 0021992502 scopus 로고
    • The limbic system and the localisation of herpes simplex encephalitis
    • Damasio A.R., Van Hoesen G.W. The limbic system and the localisation of herpes simplex encephalitis. J Neurol Neurosurg Psychiatry. 1985; 48(4): 297–301.
    • (1985) J Neurol Neurosurg Psychiatry , vol.48 , Issue.4 , pp. 297-301
    • Damasio, A.R.1    Van Hoesen, G.W.2
  • 13
    • 0025340951 scopus 로고
    • Long-term cognitive sequelae of acyclovir-treated herpes simplex encephalitis
    • Gordon B., Selnes O.A., Hart J., Hanley D.F., Whitley R.J. Long-term cognitive sequelae of acyclovir-treated herpes simplex encephalitis. Arch Neurol. 1990; 47(6): 646–7.
    • (1990) Arch Neurol , vol.47 , Issue.6 , pp. 646-647
    • Gordon, B.1    Selnes, O.A.2    Hart, J.3    Hanley, D.F.4    Whitley, R.J.5
  • 14
    • 0030768219 scopus 로고    scopus 로고
    • Herpes simplex encephalitis treated with acyclivir. diagnosis and long term outcome
    • McGrath N., Anderson N.E., Croxson M.C., Powell K.F. Herpes simplex encephalitis treated with acyclivir. diagnosis and long term outcome. J Neurol Neurosurg Psychiat 1997; 63: 321–6.
    • (1997) J Neurol Neurosurg Psychiat , vol.63 , pp. 321-326
    • McGrath, N.1    Anderson, N.E.2    Croxson, M.C.3    Powell, K.F.4
  • 15
    • 0030785611 scopus 로고    scopus 로고
    • Evaluation of the range of clinical presentations of herpes simplex encephalitis by using polymerase chain reaction assay of cerebrospinal fluid samples
    • Domingues R.B., Tsanaclis A.M., Pannuti C.S., Mayo M.S., Lakeman F.D. Evaluation of the range of clinical presentations of herpes simplex encephalitis by using polymerase chain reaction assay of cerebrospinal fluid samples. Clin Infect Dis. 1997; 25(1): 86–91.
    • (1997) Clin Infect Dis , vol.25 , Issue.1 , pp. 86-91
    • Domingues, R.B.1    Tsanaclis, A.M.2    Pannuti, C.S.3    Mayo, M.S.4    Lakeman, F.D.5
  • 16
    • 34848880752 scopus 로고    scopus 로고
    • Herpes simplex encephalitis in Sweden, 1990–2001: incidence, morbidity, and mortality
    • Hjalmarsson A., Blomqvist P., Sköldenberg B. Herpes simplex encephalitis in Sweden, 1990–2001: incidence, morbidity, and mortality. Clin Infect Dis. 2007; 45(7): 875–80.
    • (2007) Clin Infect Dis , vol.45 , Issue.7 , pp. 875-880
    • Hjalmarsson, A.1    Blomqvist, P.2    Sköldenberg, B.3
  • 18
    • 0018640937 scopus 로고
    • Identification of patients with ioncreased risk of infecltion with herpes simplex virus after renal transplantation
    • Pass R.F., Whitely R.J., Whelchel J.D., Diethelm A.G., Reinholds D.W., Alford C.A. Identification of patients with ioncreased risk of infecltion with herpes simplex virus after renal transplantation. J Infect Dis. 1979; 140: 487–92.
    • (1979) J Infect Dis , vol.140 , pp. 487-492
    • Pass, R.F.1    Whitely, R.J.2    Whelchel, J.D.3    Diethelm, A.G.4    Reinholds, D.W.5    Alford, C.A.6
  • 19
    • 13144254208 scopus 로고    scopus 로고
    • Genetic analysis of patients with defects oin early B-cell development
    • Conley M.E., Broides A., Hernande–Trujillo V. et al. Genetic analysis of patients with defects oin early B-cell development. Immunol Rev. 2005; 203: 216–34.
    • (2005) Immunol Rev , vol.203 , pp. 216-234
    • Conley, M.E.1    Broides, A.2    Hernande–Trujillo, V.3
  • 20
    • 33750016788 scopus 로고    scopus 로고
    • Herpes simplex virus encephalitis in humans UNC-93B deficiency
    • Casrouge A., Zhamg S.Y., Eidenschenk C. et al. Herpes simplex virus encephalitis in humans UNC-93B deficiency. Science. 2006; 314: 308–12.
    • (2006) Science , vol.314 , pp. 308-312
    • Casrouge, A.1    Zhamg, S.Y.2    Eidenschenk, C.3
  • 21
    • 0015077064 scopus 로고
    • Quantitative aspects of tryptophan metabolism in humans and other species: a review
    • Leklem J.E. Quantitative aspects of tryptophan metabolism in humans and other species: a review. Am J Clin Nutr. 1971; 24(6): 659–72.
    • (1971) Am J Clin Nutr , vol.24 , Issue.6 , pp. 659-672
    • Leklem, J.E.1
  • 22
    • 77950022119 scopus 로고    scopus 로고
    • CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-a: relationship to CNS immune responses and depression
    • Raison C.L., Dantzer R., Kelley K.W. et al. CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-a: relationship to CNS immune responses and depression. Mol Psychiatry. 2010; 15: 399–403.
    • (2010) Mol Psychiatry , vol.15 , pp. 399-403
    • Raison, C.L.1    Dantzer, R.2    Kelley, K.W.3
  • 23
    • 84862603083 scopus 로고    scopus 로고
    • Kynurenines in the mammalian brain: when physiology meets pathology
    • Schwarcz R., Bruno J.P., Muchowski P.J., Wu H.Q. Kynurenines in the mammalian brain: when physiology meets pathology. Nat Rev Neurosci. 2012; 13(7): 465–77.
    • (2012) Nat Rev Neurosci , vol.13 , Issue.7 , pp. 465-477
    • Schwarcz, R.1    Bruno, J.P.2    Muchowski, P.J.3    Wu, H.Q.4
  • 24
    • 31044446342 scopus 로고    scopus 로고
    • Monitoring tryptophan metabolism in chronic immune activation
    • Schröcksnadel K., Wirleitner B., Winkler C., Fuchs D. Monitoring tryptophan metabolism in chronic immune activation. Clin Chim Acta. 2006; 364(1-2): 82–90.
    • (2006) Clin Chim Acta , vol.364 , Issue.1-2 , pp. 82-90
    • Schröcksnadel, K.1    Wirleitner, B.2    Winkler, C.3    Fuchs, D.4
  • 25
    • 0023783911 scopus 로고
    • Kynurenic acid antagonises responses to NMDA via an action at the strychnine-insensitive glycine receptor
    • Birch P.J., Grossman C.J., Hayes A.G. Kynurenic acid antagonises responses to NMDA via an action at the strychnine-insensitive glycine receptor. Eur J Pharmacol. 1988; 154(1): 85–7.
    • (1988) Eur J Pharmacol , vol.154 , Issue.1 , pp. 85-87
    • Birch, P.J.1    Grossman, C.J.2    Hayes, A.G.3
  • 26
    • 0024564076 scopus 로고
    • A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonists
    • Kessler M., Terramani T., Lynch G., Baudry M. A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonists. J Neurochem. 1989; 52(4): 1319–28.
    • (1989) J Neurochem , vol.52 , Issue.4 , pp. 1319-1328
    • Kessler, M.1    Terramani, T.2    Lynch, G.3    Baudry, M.4
  • 27
    • 14444285260 scopus 로고    scopus 로고
    • Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization
    • Parsons C.G., Danysz W., Quack G. et al. Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization. J Pharmacol Exp Ther. 1997; 283(3): 1264–75.
    • (1997) J Pharmacol Exp Ther , vol.283 , Issue.3 , pp. 1264-1275
    • Parsons, C.G.1    Danysz, W.2    Quack, G.3
  • 28
    • 0035478066 scopus 로고    scopus 로고
    • The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications
    • Hilmas C., Pereira E.F., Alkondon M., Rassoulpour A., Schwarcz R., Albuquerque E.X. The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications. J Neurosci. 2001; 21(19): 7463–73.
    • (2001) J Neurosci , vol.21 , Issue.19 , pp. 7463-7473
    • Hilmas, C.1    Pereira, E.F.2    Alkondon, M.3    Rassoulpour, A.4    Schwarcz, R.5    Albuquerque, E.X.6
  • 29
    • 0021673238 scopus 로고
    • Cortical abnormalities in Alzheimer's disease
    • Foster N.L., Chase T.N., Mansi L. et al. Cortical abnormalities in Alzheimer's disease. Ann Neurol. 1984; 16: 649–54.
    • (1984) Ann Neurol , vol.16 , pp. 649-654
    • Foster, N.L.1    Chase, T.N.2    Mansi, L.3
  • 30
    • 4143096940 scopus 로고    scopus 로고
    • Endogenous kynurenic acid disrupts prepulse inhibition
    • Erhardt S., Schwieler L., Emanuelsson C., Geyer M. Endogenous kynurenic acid disrupts prepulse inhibition. Biol Psychiatry. 2004; 56(4): 255–60.
    • (2004) Biol Psychiatry , vol.56 , Issue.4 , pp. 255-260
    • Erhardt, S.1    Schwieler, L.2    Emanuelsson, C.3    Geyer, M.4
  • 31
    • 34248335693 scopus 로고    scopus 로고
    • Elevations of endogenous kynurenic acid produce spatial working memory deficits
    • Chess A.C., Simoni M.K., Alling T.E., Bucci D.J. Elevations of endogenous kynurenic acid produce spatial working memory deficits. Schizophr Bull. 2007; 33(3): 797–804.
    • (2007) Schizophr Bull , vol.33 , Issue.3 , pp. 797-804
    • Chess, A.C.1    Simoni, M.K.2    Alling, T.E.3    Bucci, D.J.4
  • 32
    • 84871863918 scopus 로고    scopus 로고
    • Exposure to kynurenic acid during adolescence produces memory deficits in adulthood
    • Akagbosu C.O., Evans G.C., Gulick D., Suckow R.F., Bucci D.J. Exposure to kynurenic acid during adolescence produces memory deficits in adulthood. Schizophr Bull. 2012; 38(4): 769–78.
    • (2012) Schizophr Bull , vol.38 , Issue.4 , pp. 769-778
    • Akagbosu, C.O.1    Evans, G.C.2    Gulick, D.3    Suckow, R.F.4    Bucci, D.J.5
  • 33
    • 84858445314 scopus 로고    scopus 로고
    • Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine
    • Alexander K.S., Wu H.Q., Schwarcz R., Bruno J.P. Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine. Psychopharmacology (Berl). 2012; 220(3): 627–37.
    • (2012) Psychopharmacology (Berl) , vol.220 , Issue.3 , pp. 627-637
    • Alexander, K.S.1    Wu, H.Q.2    Schwarcz, R.3    Bruno, J.P.4
  • 34
    • 59149090373 scopus 로고    scopus 로고
    • Pharmacological manipulation of kynurenic acid: potential in the treatment of psychiatric disorders
    • Erhardt S., Olsson S.K., Engberg G. Pharmacological manipulation of kynurenic acid: potential in the treatment of psychiatric disorders. CNS Drugs. 2009; 23(2): 91–101.
    • (2009) CNS Drugs , vol.23 , Issue.2 , pp. 91-101
    • Erhardt, S.1    Olsson, S.K.2    Engberg, G.3
  • 35
    • 84866330908 scopus 로고    scopus 로고
    • Elevated cerebrospinal fluid kynurenic acid levels in patients with tick borne encephalitis
    • Holze M., Mickienie A., Atlas A., Lindqvist L., Schwieler L. Elevated cerebrospinal fluid kynurenic acid levels in patients with tick borne encephalitis. J Intern Med. 2012; 272: 394–401.
    • (2012) J Intern Med , vol.272 , pp. 394-401
    • Holze, M.1    Mickienie, A.2    Atlas, A.3    Lindqvist, L.4    Schwieler, L.5
  • 36
    • 33845206650 scopus 로고    scopus 로고
    • Acute psychotic symptoms in HIV-1 infected patients are associated with increased levels of kynurenic acid in cerebrospinal fluid
    • Atlas A., Gisslén M., Nordin C., Lindström L., Schwieler L. Acute psychotic symptoms in HIV-1 infected patients are associated with increased levels of kynurenic acid in cerebrospinal fluid. Brain Behav Immun. 2007; 21(1): 86–91.
    • (2007) Brain Behav Immun , vol.21 , Issue.1 , pp. 86-91
    • Atlas, A.1    Gisslén, M.2    Nordin, C.3    Lindström, L.4    Schwieler, L.5
  • 37
    • 0035798252 scopus 로고    scopus 로고
    • Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia
    • Erhardt S., Blennow K., Nordin C., Skogh E., Lindström L.H., Engberg G. Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia. Neurosci Lett. 2001; 313(1-2): 96–8.
    • (2001) Neurosci Lett , vol.313 , Issue.1-2 , pp. 96-98
    • Erhardt, S.1    Blennow, K.2    Nordin, C.3    Skogh, E.4    Lindström, L.H.5    Engberg, G.6
  • 39
    • 85128711760 scopus 로고    scopus 로고
    • Elevated levels of kynurenic acid in the cerebrospinal fluid of male pateints with schizophrenia
    • Nilsson L.K., Linderholm K.R., Engberg G. et al. Elevated levels of kynurenic acid in the cerebrospinal fluid of male pateints with schizophrenia. Schizophr Res. 2005; 15: 2315–22.
    • (2005) Schizophr Res , vol.15 , pp. 2315-2322
    • Nilsson, L.K.1    Linderholm, K.R.2    Engberg, G.3
  • 40
    • 84860159640 scopus 로고    scopus 로고
    • Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia
    • Linderholm K.R., Skogh E., Olsson S.K. et al. Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia. Schizophr Bull. 2012; 38(3): 426–32.
    • (2012) Schizophr Bull , vol.38 , Issue.3 , pp. 426-432
    • Linderholm, K.R.1    Skogh, E.2    Olsson, S.K.3
  • 41
    • 77953337737 scopus 로고    scopus 로고
    • Elevated levels of kynurenic acid in the cerebrospinal fluid of patients with bipolar disorder
    • Olsson S.K., Samuelsson M., Saetre P. et al. Elevated levels of kynurenic acid in the cerebrospinal fluid of patients with bipolar disorder. J Psychiatry Neurosci. 2010; 35(3): 195–9.
    • (2010) J Psychiatry Neurosci , vol.35 , Issue.3 , pp. 195-199
    • Olsson, S.K.1    Samuelsson, M.2    Saetre, P.3
  • 42
    • 9344267366 scopus 로고
    • Early diagnosis of herpes-simplex encephalitis by brain biopsy
    • Maccallum F.O., Potter J.M., Edwards D.H. Early diagnosis of herpes-simplex encephalitis by brain biopsy. Lancet. 1964; 2(7355): 332–4.
    • (1964) Lancet , vol.2 , Issue.7355 , pp. 332-334
    • Maccallum, F.O.1    Potter, J.M.2    Edwards, D.H.3
  • 43
    • 0029905953 scopus 로고    scopus 로고
    • The role of laboratory investigation in the diagnosis and management of patients with suspected herpes simplex encephalitis: a consensus report. The EU Concerted Action on Virus Meningitis and Encephalitis
    • Cinque P., Cleator G.M., Weber T., Monteyne P., Sindic C.J., van Loon A.M. The role of laboratory investigation in the diagnosis and management of patients with suspected herpes simplex encephalitis: a consensus report. The EU Concerted Action on Virus Meningitis and Encephalitis. J Neurol Neurosurg Psychiatry. 1996; 61(4): 339–45.
    • (1996) J Neurol Neurosurg Psychiatry , vol.61 , Issue.4 , pp. 339-345
    • Cinque, P.1    Cleator, G.M.2    Weber, T.3    Monteyne, P.4    Sindic, C.J.5    van Loon, A.M.6
  • 44
    • 0025039838 scopus 로고
    • Quantification of kynurenic acid in cerebrospinal fluid: effects of systemic and central L-kynurenine administration
    • Heyes M.P., Quearry B.J. Quantification of kynurenic acid in cerebrospinal fluid: effects of systemic and central L-kynurenine administration. J Chromatogr. 1990; 530(1): 108–15.
    • (1990) J Chromatogr , vol.530 , Issue.1 , pp. 108-115
    • Heyes, M.P.1    Quearry, B.J.2
  • 45
    • 11144314849 scopus 로고    scopus 로고
    • Expression of indoleamine 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons
    • Guillemin G.J., Smythe G., Takikawa O., Brew B.J. Expression of indoleamine 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons. Glia. 2005; 49(1): 15–23.
    • (2005) Glia , vol.49 , Issue.1 , pp. 15-23
    • Guillemin, G.J.1    Smythe, G.2    Takikawa, O.3    Brew, B.J.4
  • 46
    • 0027978743 scopus 로고
    • Cytokines and other markers of intrathecal immune response in patients with herpes simplex encephalitis
    • Aurelius E., Andersson B., Forsgren M., Sköldenberg B., Strannegård O. Cytokines and other markers of intrathecal immune response in patients with herpes simplex encephalitis. J Infect Dis. 1994; 170(3): 678–81.
    • (1994) J Infect Dis , vol.170 , Issue.3 , pp. 678-681
    • Aurelius, E.1    Andersson, B.2    Forsgren, M.3    Sköldenberg, B.4    Strannegård, O.5
  • 47
    • 52949130640 scopus 로고    scopus 로고
    • Cerebrospinal fluid levels of cytokines in non-herpetic acute limbic encephalitis: comparison with herpes simplex encephalitis
    • Ichiyama T., Shoji H., Takahashi Y. et al. Cerebrospinal fluid levels of cytokines in non-herpetic acute limbic encephalitis: comparison with herpes simplex encephalitis. Cytokine. 2008; 44(1): 149–53.
    • (2008) Cytokine , vol.44 , Issue.1 , pp. 149-153
    • Ichiyama, T.1    Shoji, H.2    Takahashi, Y.3
  • 48
    • 0031920895 scopus 로고    scopus 로고
    • Altered tryptophan metabolism in mice with herpes simplex virus encephalitis: increases in spinal cord quinolinic acid
    • Reinhard J.F. Altered tryptophan metabolism in mice with herpes simplex virus encephalitis: increases in spinal cord quinolinic acid. Neurochem Res. 1998; 23(5): 661–5.
    • (1998) Neurochem Res , vol.23 , Issue.5 , pp. 661-665
    • Reinhard, J.F.1
  • 49
    • 84859610302 scopus 로고    scopus 로고
    • Kynurenine pathway inhibition as a therapeutic strategy for neuroprotection
    • Stone T.W., Forrest C.M., Darlington L.G. Kynurenine pathway inhibition as a therapeutic strategy for neuroprotection. FEBS J. 2012; 279(8): 1386–97.
    • (2012) FEBS J , vol.279 , Issue.8 , pp. 1386-1397
    • Stone, T.W.1    Forrest, C.M.2    Darlington, L.G.3
  • 50
    • 0000056144 scopus 로고
    • Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cell to degradate tryptophan
    • Pfefferkorn E.R. Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cell to degradate tryptophan. Proc Natl Acad Sci USA. 1984; 81: 908–12.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 908-912
    • Pfefferkorn, E.R.1
  • 51
    • 77951737056 scopus 로고    scopus 로고
    • Gut CD103+ dendritic cells express indoleamine 2, 3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction
    • Matteoli G., Mazzini E., Iliev I.D. et al. Gut CD103+ dendritic cells express indoleamine 2, 3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction. Gut. 2010; 59: 595–604.
    • (2010) Gut , vol.59 , pp. 595-604
    • Matteoli, G.1    Mazzini, E.2    Iliev, I.D.3
  • 52
    • 78650673114 scopus 로고    scopus 로고
    • IDO upregulates regulatory T cells via tryptophan catabolite and suppresses encephalitogenic T cell responses in experimental autoimmune encephalomyelitis
    • Yan Y., Zhang G.X., Gran B. et al. IDO upregulates regulatory T cells via tryptophan catabolite and suppresses encephalitogenic T cell responses in experimental autoimmune encephalomyelitis. J Immunol. 2010; 185(10): 5953–61.
    • (2010) J Immunol , vol.185 , Issue.10 , pp. 5953-5961
    • Yan, Y.1    Zhang, G.X.2    Gran, B.3
  • 53
    • 38449110163 scopus 로고    scopus 로고
    • The characterization and role of regulatory T cells in immune reactions
    • Wilczynski J.R., Radwan M., Kalinka J. The characterization and role of regulatory T cells in immune reactions. Front Biosci. 2008; 13: 2266–74.
    • (2008) Front Biosci , vol.13 , pp. 2266-2274
    • Wilczynski, J.R.1    Radwan, M.2    Kalinka, J.3
  • 54
    • 27144489077 scopus 로고    scopus 로고
    • Inhibition of indoleamine 2, 3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis
    • Potula R., Poluektova L., Knipe B. et al. Inhibition of indoleamine 2, 3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis. Blood. 2005; 106: 2382–90.
    • (2005) Blood , vol.106 , pp. 2382-2390
    • Potula, R.1    Poluektova, L.2    Knipe, B.3
  • 55
    • 0019440926 scopus 로고
    • Quinolinic acid: a potent endogenous excitant at amino acid receptors in CNS
    • Stone T.W., Perkins M.N. Quinolinic acid: a potent endogenous excitant at amino acid receptors in CNS. Eur J Pharmacol. 1981; 72(4): 411–2.
    • (1981) Eur J Pharmacol , vol.72 , Issue.4 , pp. 411-412
    • Stone, T.W.1    Perkins, M.N.2
  • 56
    • 0020591879 scopus 로고
    • Differential vulnerability of central neurons of the rat to quinolinic acid
    • Schwarcz R., Köhler C. Differential vulnerability of central neurons of the rat to quinolinic acid. Neurosci Lett. 1983; 38(1): 85–90.
    • (1983) Neurosci Lett , vol.38 , Issue.1 , pp. 85-90
    • Schwarcz, R.1    Köhler, C.2
  • 57
    • 0030341765 scopus 로고    scopus 로고
    • The neurotoxin quinolinic acid is increased in spinal cords of mice with herpes simplex virus encephalitis
    • Reinhard J.F., Flanagan E.M. The neurotoxin quinolinic acid is increased in spinal cords of mice with herpes simplex virus encephalitis. Adv Exp Med Biol. 1996; 398: 241–6.
    • (1996) Adv Exp Med Biol , vol.398 , pp. 241-246
    • Reinhard, J.F.1    Flanagan, E.M.2
  • 58
    • 29144485791 scopus 로고    scopus 로고
    • Endogenous qunurenate controls the vulnerability of striatal neurons to quinolinate: implications for Huntington's disease
    • Sapko M.T., Guidetti P., Ju P., Tagle D.A., Pelliccjari R., Schwarcz R. Endogenous qunurenate controls the vulnerability of striatal neurons to quinolinate: implications for Huntington's disease. Exp Neurol. 2006; 197: 31–40.
    • (2006) Exp Neurol , vol.197 , pp. 31-40
    • Sapko, M.T.1    Guidetti, P.2    Ju, P.3    Tagle, D.A.4    Pelliccjari, R.5    Schwarcz, R.6
  • 60
    • 84868092047 scopus 로고    scopus 로고
    • Cerebrospinal fluid kynurenic acid is associated with manic and psychotic features in patients with bipolar I disorder
    • Olsson S.K., Sellgren C., Engberg G., Landén M., Erhardt S. Cerebrospinal fluid kynurenic acid is associated with manic and psychotic features in patients with bipolar I disorder. Bipolar Disord. 2012; 14(7): 719–26.
    • (2012) Bipolar Disord , vol.14 , Issue.7 , pp. 719-726
    • Olsson, S.K.1    Sellgren, C.2    Engberg, G.3    Landén, M.4    Erhardt, S.5
  • 61
    • 33645096364 scopus 로고    scopus 로고
    • Behavioural pharmacology: 40+ years of progress, with a focus on glutamate receptors and cognition
    • Robbins T.W., Murphy E.R. Behavioural pharmacology: 40+ years of progress, with a focus on glutamate receptors and cognition. Trends Pharmacol Sci. 2006; 27(3): 141–8.
    • (2006) Trends Pharmacol Sci , vol.27 , Issue.3 , pp. 141-148
    • Robbins, T.W.1    Murphy, E.R.2
  • 62
    • 84863116237 scopus 로고    scopus 로고
    • Characterization of Non-nitrocatechol pan and isoform specific catechol-o-methyltransferase inhibitors and substrates
    • Robinson R.G., Smith S.M., Wolkensberg S.E. et al. Characterization of Non-nitrocatechol pan and isoform specific catechol-o-methyltransferase inhibitors and substrates. ACS Chem Neurosci. 2011; 3: 129–40.
    • (2011) ACS Chem Neurosci , vol.3 , pp. 129-140
    • Robinson, R.G.1    Smith, S.M.2    Wolkensberg, S.E.3
  • 63
    • 77953617514 scopus 로고    scopus 로고
    • Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior
    • Potter M.C., Elmer G.I., Bergeron R. et al. Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior. Neuropsychopharmacology. 2010; 35(8): 1734–42.
    • (2010) Neuropsychopharmacology , vol.35 , Issue.8 , pp. 1734-1742
    • Potter, M.C.1    Elmer, G.I.2    Bergeron, R.3
  • 64
    • 0023109220 scopus 로고
    • Multihormonal regulation of transcription of the tryptophan 2,3-dioxygenase gene in primary cultures of adult rat hepatocytes with special reference to the presence of a transcriptional protein mediating the action of glucocorticoids
    • Nakamura T., Niimi S., Nawa K. et al. Multihormonal regulation of transcription of the tryptophan 2,3-dioxygenase gene in primary cultures of adult rat hepatocytes with special reference to the presence of a transcriptional protein mediating the action of glucocorticoids. J Biol Chem. 1987; 262(2): 727–33.
    • (1987) J Biol Chem , vol.262 , Issue.2 , pp. 727-733
    • Nakamura, T.1    Niimi, S.2    Nawa, K.3
  • 66
    • 36348960240 scopus 로고    scopus 로고
    • Impaired dexamethasone-mediated induction of tryptophan 2,3-dioxygenase in heme-deficient rat hepatocytes: translational control by a hepatic eIF2alpha kinase, the heme-regulated inhibitor
    • Liao M., Pabarcus M.K., Wang Y. et al. Impaired dexamethasone-mediated induction of tryptophan 2,3-dioxygenase in heme-deficient rat hepatocytes: translational control by a hepatic eIF2alpha kinase, the heme-regulated inhibitor. J Pharmacol Exp Ther. 2007; 323(3): 979–89.
    • (2007) J Pharmacol Exp Ther , vol.323 , Issue.3 , pp. 979-989
    • Liao, M.1    Pabarcus, M.K.2    Wang, Y.3
  • 67
    • 33745119043 scopus 로고    scopus 로고
    • Enhancement of brain kynurenic acid production by anticonvulsants–novel mechanism of antiepileptic activity?
    • Kocki T., Wielosz M., Turski W.A., Urbanska E.M. Enhancement of brain kynurenic acid production by anticonvulsants–novel mechanism of antiepileptic activity? Eur J Pharmacol. 2006; 541(3): 147–51.
    • (2006) Eur J Pharmacol , vol.541 , Issue.3 , pp. 147-151
    • Kocki, T.1    Wielosz, M.2    Turski, W.A.3    Urbanska, E.M.4
  • 68
    • 33846626403 scopus 로고    scopus 로고
    • Mechanisms by which acyclovir reduces the oxidative neurotoxicity and biosynthesis of quinolinic acid
    • Müller A.C., Dairam A., Limson J.L., Daya S. Mechanisms by which acyclovir reduces the oxidative neurotoxicity and biosynthesis of quinolinic acid. Life Sci. 2007; 80(10): 918–25.
    • (2007) Life Sci , vol.80 , Issue.10 , pp. 918-925
    • Müller, A.C.1    Dairam, A.2    Limson, J.L.3    Daya, S.4
  • 69
    • 50049120232 scopus 로고    scopus 로고
    • Acyclovir inhibits rat liver tryptophan-2,3-dioxygenase and induces a concomitant rise in brain serotonin and 5-hydroxyindole acetic acid levels
    • Müller C., Daya S. Acyclovir inhibits rat liver tryptophan-2,3-dioxygenase and induces a concomitant rise in brain serotonin and 5-hydroxyindole acetic acid levels. Metab Brain Dis. 2008; 23: 351–60.
    • (2008) Metab Brain Dis , vol.23 , pp. 351-360
    • Müller, C.1    Daya, S.2


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