Preanalytical variables and performance of diagnostic RNA-based gene expression analysis in breast cancer

Virchows Archiv

Volumn 465, Issue 4, 2014, Pages 409-417

  Poremba, Christopher ^a,b   Uhlendorff, Jennifer ^c   Pfitzner, Berit M ^d   Hennig, Guido ^e   Bohmann, Kerstin ^c   Bojar, Hans ^b   Krenn, Veit ^f   Brase, Jan C ^c   Haufe, Franziska ^c   Averdick, Manuela ^c   Dietel, Manfred ^d   Kronenwett, Ralf ^c,g   Denkert, Carsten ^d  

^a Pathology Munich North   (Germany)

^b Center for Molecular Oncology and Molecular Pathology   (Germany)

^c Sividon Diagnostics GmbH   (Germany)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e Siemens Healthcare Diagnostics Holding GmbH   (Germany)

^f Zentrum fur Histologie Zytologie und Molekulare Diagnostik   (Germany)

^g HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Breast cancer; EndoPredict; Gene expression; Molecular pathology; Preanalytical

Indexed keywords

FORMALDEHYDE; RNA; PARAFFIN;

ARTICLE; AZGP1 GENE; BIRC5 GENE; BREAST CANCER; CANCER PATIENT; CANCER RECURRENCE; CANCER TISSUE; CONTROLLED STUDY; CORRELATION COEFFICIENT; DHCR7 GENE; ESTROGEN RECEPTOR POSITIVE BREAST CANCER; GENE; GENE EXPRESSION ASSAY; HUMAN; HUMAN TISSUE; IL6ST GENE; MGP GENE; POLYMERASE CHAIN REACTION SYSTEM; RBBP8 GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; STC2 GENE; TIME; TISSUE FIXATION; TISSUE PRESERVATION; TISSUE SECTION; TUMOR CELL; UBE2C GENE; BREAST TUMOR; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; LABORATORY DIAGNOSIS; MOLECULAR PATHOLOGY; PROCEDURES;

BREAST NEOPLASMS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PARAFFIN EMBEDDING; PATHOLOGY, MOLECULAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SPECIMEN HANDLING; TIME FACTORS; TISSUE FIXATION;

EID: 84919397747     PISSN: 09456317     EISSN: 14322307     Source Type: Journal    
DOI: 10.1007/s00428-014-1652-0     Document Type: Article

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