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Volumn 45, Issue s1, 2015, Pages 32-36

Bisphenol A as epigenetic modulator: Setting the stage for carcinogenesis?

Author keywords

Bisphenol A; Cancer; Endocrine disrupting chemicals; Epigenetics; Epigenotoxicity

Indexed keywords

BENZHYDRYL COMPOUNDS; BISPHENOL A; ENDOCRINE DISRUPTORS; ESTROGENS, NON-STEROIDAL; PHENOLS;

EID: 84919363527     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/eci.12362     Document Type: Review
Times cited : (42)

References (50)
  • 1
    • 84896030401 scopus 로고    scopus 로고
    • Bisphenol A-sources, toxicity and biotransformation
    • Michalowicz J. Bisphenol A-sources, toxicity and biotransformation. Environ Toxicol Pharmacol 2014;37:738-58.
    • (2014) Environ Toxicol Pharmacol , vol.37 , pp. 738-758
    • Michalowicz, J.1
  • 3
    • 84905001393 scopus 로고    scopus 로고
    • Bisphenol-A: epigenetic reprogramming and effects on reproduction and behavior
    • Mileva G, Baker S, Konkle A, Bielajew C. Bisphenol-A: epigenetic reprogramming and effects on reproduction and behavior. Int J Environ Res Public Health 2014;11:7537-61.
    • (2014) Int J Environ Res Public Health , vol.11 , pp. 7537-7561
    • Mileva, G.1    Baker, S.2    Konkle, A.3    Bielajew, C.4
  • 5
    • 79960980803 scopus 로고    scopus 로고
    • Bisphenol A: an endocrine disruptor with widespread exposure and multiple effects
    • Rubin BS. Bisphenol A: an endocrine disruptor with widespread exposure and multiple effects. J Steroid Biochem Mol Biol 2011;127:27-34.
    • (2011) J Steroid Biochem Mol Biol , vol.127 , pp. 27-34
    • Rubin, B.S.1
  • 6
    • 84891071253 scopus 로고    scopus 로고
    • Bisphenol A and human chronic diseases: current evidences, possible mechanisms, and future perspectives
    • Rezg R, El-Fazaa S, Gharbi N, Mornagui B. Bisphenol A and human chronic diseases: current evidences, possible mechanisms, and future perspectives. Environ Int 2014;64:83-90.
    • (2014) Environ Int , vol.64 , pp. 83-90
    • Rezg, R.1    El-Fazaa, S.2    Gharbi, N.3    Mornagui, B.4
  • 7
    • 25144461103 scopus 로고    scopus 로고
    • Bisphenol A: a scientific evaluation
    • Kamrin MA. Bisphenol A: a scientific evaluation. MedGenMed 2004;6:7.
    • (2004) MedGenMed , vol.6 , pp. 7
    • Kamrin, M.A.1
  • 8
    • 0036802304 scopus 로고    scopus 로고
    • Metabolism and kinetics of bisphenol a in humans at low doses following oral administration
    • Volkel W, Colnot T, Csanady GA, Filser JG, Dekant W. Metabolism and kinetics of bisphenol a in humans at low doses following oral administration. Chem Res Toxicol 2002;15:1281-7.
    • (2002) Chem Res Toxicol , vol.15 , pp. 1281-1287
    • Volkel, W.1    Colnot, T.2    Csanady, G.A.3    Filser, J.G.4    Dekant, W.5
  • 11
    • 0034122777 scopus 로고    scopus 로고
    • Activity of environmentally relevant low doses of endocrine disruptors and the bisphenol A controversy: initial results confirmed
    • Sheehan DM. Activity of environmentally relevant low doses of endocrine disruptors and the bisphenol A controversy: initial results confirmed. Proc Soc Exp Biol Med 2000;224:57-60.
    • (2000) Proc Soc Exp Biol Med , vol.224 , pp. 57-60
    • Sheehan, D.M.1
  • 12
    • 84884306178 scopus 로고    scopus 로고
    • Bisphenol A and human health: a review of the literature
    • Rochester JR. Bisphenol A and human health: a review of the literature. Reprod Toxicol 2013;42:132-55.
    • (2013) Reprod Toxicol , vol.42 , pp. 132-155
    • Rochester, J.R.1
  • 14
    • 33750992478 scopus 로고    scopus 로고
    • Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: a potential novel mechanism of endocrine disruption
    • Thomas P, Dong J. Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: a potential novel mechanism of endocrine disruption. J Steroid Biochem Mol Biol 2006;102:175-9.
    • (2006) J Steroid Biochem Mol Biol , vol.102 , pp. 175-179
    • Thomas, P.1    Dong, J.2
  • 15
    • 33750741986 scopus 로고    scopus 로고
    • Effect of bisphenol A, tetrachlorobisphenol A and pentachlorophenol on the transcriptional activities of androgen receptor-mediated reporter gene
    • Sun H, Xu LC, Chen JF, Song L, Wang XR. Effect of bisphenol A, tetrachlorobisphenol A and pentachlorophenol on the transcriptional activities of androgen receptor-mediated reporter gene. Food Chem Toxicol 2006;44:1916-21.
    • (2006) Food Chem Toxicol , vol.44 , pp. 1916-1921
    • Sun, H.1    Xu, L.C.2    Chen, J.F.3    Song, L.4    Wang, X.R.5
  • 16
    • 0037381213 scopus 로고    scopus 로고
    • Structure and dynamic behavior of nucleosomes
    • Luger K. Structure and dynamic behavior of nucleosomes. Curr Opin Genet Dev 2003;13:127-35.
    • (2003) Curr Opin Genet Dev , vol.13 , pp. 127-135
    • Luger, K.1
  • 18
    • 70249150993 scopus 로고    scopus 로고
    • Formation of adducts by bisphenol A, an endocrine disruptor, in DNA in vitro and in liver and mammary tissue of mice
    • Izzotti A, Kanitz S, D'Agostini F, Camoirano A, De Flora S. Formation of adducts by bisphenol A, an endocrine disruptor, in DNA in vitro and in liver and mammary tissue of mice. Mutat Res 2009;679:28-32.
    • (2009) Mutat Res , vol.679 , pp. 28-32
    • Izzotti, A.1    Kanitz, S.2    D'Agostini, F.3    Camoirano, A.4    De Flora, S.5
  • 19
    • 0032545649 scopus 로고    scopus 로고
    • Bisphenol-A induces cellular transformation, aneuploidy and DNA adduct formation in cultured Syrian hamster embryo cells
    • Tsutsui T, Tamura Y, Yagi E, Hasegawa K, Takahashi M, Maizumi N et al. Bisphenol-A induces cellular transformation, aneuploidy and DNA adduct formation in cultured Syrian hamster embryo cells. Int J Cancer 1998;75:290-4.
    • (1998) Int J Cancer , vol.75 , pp. 290-294
    • Tsutsui, T.1    Tamura, Y.2    Yagi, E.3    Hasegawa, K.4    Takahashi, M.5    Maizumi, N.6
  • 20
    • 79961009690 scopus 로고    scopus 로고
    • Upregulation of clusterin in prostate and DNA damage in spermatozoa from bisphenol A-treated rats and formation of DNA adducts in cultured human prostatic cells
    • De Flora S, Micale RT, La Maestra S, Izzotti A, D'Agostini F, Camoirano A et al. Upregulation of clusterin in prostate and DNA damage in spermatozoa from bisphenol A-treated rats and formation of DNA adducts in cultured human prostatic cells. Toxicol Sci 2011;122:45-51.
    • (2011) Toxicol Sci , vol.122 , pp. 45-51
    • De Flora, S.1    Micale, R.T.2    La Maestra, S.3    Izzotti, A.4    D'Agostini, F.5    Camoirano, A.6
  • 21
    • 79951989428 scopus 로고    scopus 로고
    • Is bisphenol A a weak carcinogen like the natural estrogens and diethylstilbestrol?
    • Cavalieri EL, Rogan EG. Is bisphenol A a weak carcinogen like the natural estrogens and diethylstilbestrol? IUBMB Life 2010;62:746-51.
    • (2010) IUBMB Life , vol.62 , pp. 746-751
    • Cavalieri, E.L.1    Rogan, E.G.2
  • 22
    • 0029005176 scopus 로고
    • In vitro conversion of environmental estrogenic chemical bisphenol A to DNA binding metabolite(s)
    • Atkinson A, Roy D. In vitro conversion of environmental estrogenic chemical bisphenol A to DNA binding metabolite(s). Biochem Biophys Res Commun 1995;210:424-33.
    • (1995) Biochem Biophys Res Commun , vol.210 , pp. 424-433
    • Atkinson, A.1    Roy, D.2
  • 23
    • 32044439601 scopus 로고    scopus 로고
    • DNA damage caused by bisphenol A and estradiol through estrogenic activity
    • Iso T, Watanabe T, Iwamoto T, Shimamoto A, Furuichi Y. DNA damage caused by bisphenol A and estradiol through estrogenic activity. Biol Pharm Bull 2006;29:206-10.
    • (2006) Biol Pharm Bull , vol.29 , pp. 206-210
    • Iso, T.1    Watanabe, T.2    Iwamoto, T.3    Shimamoto, A.4    Furuichi, Y.5
  • 24
    • 84880176878 scopus 로고    scopus 로고
    • Mutagenic effect of Bisphenol A on adult rat male germ cells and their fertility
    • Tiwari D, Vanage G. Mutagenic effect of Bisphenol A on adult rat male germ cells and their fertility. Reprod Toxicol 2013;40:60-8.
    • (2013) Reprod Toxicol , vol.40 , pp. 60-68
    • Tiwari, D.1    Vanage, G.2
  • 25
    • 84886905195 scopus 로고    scopus 로고
    • In vitro effects of bisphenol A on the quality parameters, oxidative stress, DNA integrity and adenosine triphosphate content in sterlet (Acipenser ruthenus) spermatozoa
    • Hulak M, Gazo I, Shaliutina A, Linhartova P. In vitro effects of bisphenol A on the quality parameters, oxidative stress, DNA integrity and adenosine triphosphate content in sterlet (Acipenser ruthenus) spermatozoa. Comp Biochem Physiol C Toxicol Pharmacol 2013;158:64-71.
    • (2013) Comp Biochem Physiol C Toxicol Pharmacol , vol.158 , pp. 64-71
    • Hulak, M.1    Gazo, I.2    Shaliutina, A.3    Linhartova, P.4
  • 26
    • 78650555388 scopus 로고    scopus 로고
    • Bisphenol A impairs the double-strand break repair machinery in the germline and causes chromosome abnormalities
    • Allard P, Colaiacovo MP. Bisphenol A impairs the double-strand break repair machinery in the germline and causes chromosome abnormalities. Proc Natl Acad Sci U S A 2010;107:20405-10.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 20405-20410
    • Allard, P.1    Colaiacovo, M.P.2
  • 27
    • 84925659063 scopus 로고    scopus 로고
    • Reshaping chromatin after DNA damage: the choreography of histone proteins
    • Polo SE. Reshaping chromatin after DNA damage: the choreography of histone proteins. J Mol Biol 2014;doi: 10.1016/j.jmb.2014.05.025.
    • (2014) J Mol Biol
    • Polo, S.E.1
  • 28
    • 84870904979 scopus 로고    scopus 로고
    • Histone H2A.Z controls a critical chromatin remodeling step required for DNA double-strand break repair
    • Xu Y, Ayrapetov MK, Xu C, Gursoy-Yuzugullu O, Hu Y, Price BD. Histone H2A.Z controls a critical chromatin remodeling step required for DNA double-strand break repair. Mol Cell 2012;48:723-33.
    • (2012) Mol Cell , vol.48 , pp. 723-733
    • Xu, Y.1    Ayrapetov, M.K.2    Xu, C.3    Gursoy-Yuzugullu, O.4    Hu, Y.5    Price, B.D.6
  • 29
    • 77957738825 scopus 로고    scopus 로고
    • The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair
    • Xu Y, Sun Y, Jiang X, Ayrapetov MK, Moskwa P, Yang S et al. The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair. J Cell Biol 2010;191:31-43.
    • (2010) J Cell Biol , vol.191 , pp. 31-43
    • Xu, Y.1    Sun, Y.2    Jiang, X.3    Ayrapetov, M.K.4    Moskwa, P.5    Yang, S.6
  • 30
    • 35148894396 scopus 로고    scopus 로고
    • DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics
    • Ikura T, Tashiro S, Kakino A, Shima H, Jacob N, Amunugama R et al. DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics. Mol Cell Biol 2007;27:7028-40.
    • (2007) Mol Cell Biol , vol.27 , pp. 7028-7040
    • Ikura, T.1    Tashiro, S.2    Kakino, A.3    Shima, H.4    Jacob, N.5    Amunugama, R.6
  • 31
    • 67650409769 scopus 로고    scopus 로고
    • Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells
    • Tjeertes JV, Miller KM, Jackson SP. Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. EMBO J 2009;28:1878-89.
    • (2009) EMBO J , vol.28 , pp. 1878-1889
    • Tjeertes, J.V.1    Miller, K.M.2    Jackson, S.P.3
  • 32
    • 65549113750 scopus 로고    scopus 로고
    • CBP/p300-mediated acetylation of histone H3 on lysine 56
    • Das C, Lucia MS, Hansen KC, Tyler JK. CBP/p300-mediated acetylation of histone H3 on lysine 56. Nature 2009;459:113-7.
    • (2009) Nature , vol.459 , pp. 113-117
    • Das, C.1    Lucia, M.S.2    Hansen, K.C.3    Tyler, J.K.4
  • 33
    • 80054782483 scopus 로고    scopus 로고
    • The dual role of sirtuins in cancer
    • Bosch-Presegue L, Vaquero A. The dual role of sirtuins in cancer. Genes Cancer 2011;2:648-62.
    • (2011) Genes Cancer , vol.2 , pp. 648-662
    • Bosch-Presegue, L.1    Vaquero, A.2
  • 35
    • 78549288551 scopus 로고    scopus 로고
    • DNA methyltransferase 1-associated protein (DMAP1) is a co-repressor that stimulates DNA methylation globally and locally at sites of double strand break repair
    • Lee GE, Kim JH, Taylor M, Muller MT. DNA methyltransferase 1-associated protein (DMAP1) is a co-repressor that stimulates DNA methylation globally and locally at sites of double strand break repair. J Biol Chem 2010;285:37630-40.
    • (2010) J Biol Chem , vol.285 , pp. 37630-37640
    • Lee, G.E.1    Kim, J.H.2    Taylor, M.3    Muller, M.T.4
  • 36
    • 79952202310 scopus 로고    scopus 로고
    • Epigenomic disruption: the effects of early developmental exposures
    • Bernal AJ, Jirtle RL. Epigenomic disruption: the effects of early developmental exposures. Birth Defects Res A Clin Mol Teratol 2010;88:938-44.
    • (2010) Birth Defects Res A Clin Mol Teratol , vol.88 , pp. 938-944
    • Bernal, A.J.1    Jirtle, R.L.2
  • 37
    • 84901764521 scopus 로고    scopus 로고
    • F0 maternal BPA exposure induced glucose intolerance of F2 generation through DNA methylation change in Gck
    • Li G, Chang H, Xia W, Mao Z, Li Y, Xu S. F0 maternal BPA exposure induced glucose intolerance of F2 generation through DNA methylation change in Gck. Toxicol Lett 2014;228:192-9.
    • (2014) Toxicol Lett , vol.228 , pp. 192-199
    • Li, G.1    Chang, H.2    Xia, W.3    Mao, Z.4    Li, Y.5    Xu, S.6
  • 39
    • 0037041272 scopus 로고    scopus 로고
    • Improvement of a two-stage carcinogenesis model to detect modifying effects of endocrine disrupting chemicals on thyroid carcinogenesis in rats
    • Takagi H, Mitsumori K, Onodera H, Nasu M, Tamura T, Yasuhara K et al. Improvement of a two-stage carcinogenesis model to detect modifying effects of endocrine disrupting chemicals on thyroid carcinogenesis in rats. Cancer Lett 2002;178:1-9.
    • (2002) Cancer Lett , vol.178 , pp. 1-9
    • Takagi, H.1    Mitsumori, K.2    Onodera, H.3    Nasu, M.4    Tamura, T.5    Yasuhara, K.6
  • 40
    • 84859850513 scopus 로고    scopus 로고
    • Environmental estrogens differentially engage the histone methyltransferase EZH2 to increase risk of uterine tumorigenesis
    • Greathouse KL, Bredfeldt T, Everitt JI, Lin K, Berry T, Kannan K et al. Environmental estrogens differentially engage the histone methyltransferase EZH2 to increase risk of uterine tumorigenesis. Mol Cancer Res 2012;10:546-57.
    • (2012) Mol Cancer Res , vol.10 , pp. 546-557
    • Greathouse, K.L.1    Bredfeldt, T.2    Everitt, J.I.3    Lin, K.4    Berry, T.5    Kannan, K.6
  • 42
    • 34548715144 scopus 로고    scopus 로고
    • Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development
    • Dolinoy DC, Huang D, Jirtle RL. Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development. Proc Natl Acad Sci U S A 2007;104:13056-61.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 13056-13061
    • Dolinoy, D.C.1    Huang, D.2    Jirtle, R.L.3
  • 43
    • 84903779504 scopus 로고    scopus 로고
    • Prenatal exposure to BPA alters the epigenome of the rat mammary gland and increases the propensity to neoplastic development
    • Dhimolea E, Wadia PR, Murray TJ, Settles ML, Treitman JD, Sonnenschein C et al. Prenatal exposure to BPA alters the epigenome of the rat mammary gland and increases the propensity to neoplastic development. PLoS ONE 2014;9:e99800.
    • (2014) PLoS ONE , vol.9 , pp. e99800
    • Dhimolea, E.1    Wadia, P.R.2    Murray, T.J.3    Settles, M.L.4    Treitman, J.D.5    Sonnenschein, C.6
  • 44
    • 33745246032 scopus 로고    scopus 로고
    • Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4
    • Ho SM, Tang WY, Belmonte de Frausto J, Prins GS. Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4. Cancer Res 2006;66:5624-32.
    • (2006) Cancer Res , vol.66 , pp. 5624-5632
    • Ho, S.M.1    Tang, W.Y.2    Belmonte de Frausto, J.3    Prins, G.S.4
  • 45
    • 84875536948 scopus 로고    scopus 로고
    • Gene expression of epigenetic regulatory factors related to primary silencing mechanism is less susceptible to lower doses of bisphenol A in embryonic hypothalamic cells
    • Warita K, Mitsuhashi T, Ohta K, Suzuki S, Hoshi N, Miki T et al. Gene expression of epigenetic regulatory factors related to primary silencing mechanism is less susceptible to lower doses of bisphenol A in embryonic hypothalamic cells. J Toxicol Sci 2013;38:285-9.
    • (2013) J Toxicol Sci , vol.38 , pp. 285-289
    • Warita, K.1    Mitsuhashi, T.2    Ohta, K.3    Suzuki, S.4    Hoshi, N.5    Miki, T.6
  • 46
    • 33644765912 scopus 로고    scopus 로고
    • Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer
    • Collett K, Eide GE, Arnes J, Stefansson IM, Eide J, Braaten A et al. Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer. Clin Cancer Res 2006;12:1168-74.
    • (2006) Clin Cancer Res , vol.12 , pp. 1168-1174
    • Collett, K.1    Eide, G.E.2    Arnes, J.3    Stefansson, I.M.4    Eide, J.5    Braaten, A.6
  • 47
    • 77955552108 scopus 로고    scopus 로고
    • In utero exposure to diethylstilbestrol (DES) or bisphenol-A (BPA) increases EZH2 expression in the mammary gland: an epigenetic mechanism linking endocrine disruptors to breast cancer
    • Doherty LF, Bromer JG, Zhou Y, Aldad TS, Taylor HS. In utero exposure to diethylstilbestrol (DES) or bisphenol-A (BPA) increases EZH2 expression in the mammary gland: an epigenetic mechanism linking endocrine disruptors to breast cancer. Horm Cancer 2010;1:146-55.
    • (2010) Horm Cancer , vol.1 , pp. 146-155
    • Doherty, L.F.1    Bromer, J.G.2    Zhou, Y.3    Aldad, T.S.4    Taylor, H.S.5
  • 48
    • 84895764137 scopus 로고    scopus 로고
    • Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo
    • Bhan A, Hussain I, Ansari KI, Bobzean SA, Perrotti LI, Mandal SS. Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo. J Steroid Biochem Mol Biol 2014;141:160-70.
    • (2014) J Steroid Biochem Mol Biol , vol.141 , pp. 160-170
    • Bhan, A.1    Hussain, I.2    Ansari, K.I.3    Bobzean, S.A.4    Perrotti, L.I.5    Mandal, S.S.6
  • 49
    • 77951118936 scopus 로고    scopus 로고
    • Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
    • Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature 2010;464:1071-6.
    • (2010) Nature , vol.464 , pp. 1071-1076
    • Gupta, R.A.1    Shah, N.2    Wang, K.C.3    Kim, J.4    Horlings, H.M.5    Wong, D.J.6


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