Prenatal exposure to BPA alters the epigenome of the rat mammary gland and increases the propensity to neoplastic development

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Dhimolea, Eugen ^a   Wadia, Perinaaz R ^a   Murray, Tessa J ^a   Settles, Matthew L ^b   Treitman, Jo D ^a   Sonnenschein, Carlos ^a   Shioda, Toshi ^c   Soto, Ana M ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF IDAHO   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ALPHA LACTALBUMIN; DNA; HISTONE H3; HISTONE H3K4; MESSENGER RNA; UNCLASSIFIED DRUG; 5 METHYLCYTOSINE; ANTIBODY; BENZHYDRYL DERIVATIVE; HISTONE; LACTALBUMIN; PHENOL DERIVATIVE;

ADULT; ALPHA LACTALBUMIN GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST DEVELOPMENT; CANCER GROWTH; CONTROLLED STUDY; DNA DETERMINATION; DNA ISOLATION; DNA METHYLATION; EMBRYO DEVELOPMENT; ENVIRONMENTAL EXPOSURE; EPIGENETICS; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; IMMUNOPRECIPITATION; INTRADUCTAL CARCINOMA; MAMMARY GLAND; NONHUMAN; PRENATAL EXPOSURE; PROMOTER REGION; PROTEIN METHYLATION; RAT; TRANSCRIPTOMICS; ANIMAL; BLOOD; CARCINOGENESIS; DNA MICROARRAY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; IMMUNOLOGY; METABOLISM; PREGNANCY; TANDEM MASS SPECTROMETRY; TRANSCRIPTION INITIATION SITE; UDDER; WISTAR RAT;

5-METHYLCYTOSINE; ANIMALS; ANTIBODIES; BENZHYDRYL COMPOUNDS; CARCINOGENESIS; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION; HISTONES; LACTALBUMIN; MAMMARY GLANDS, ANIMAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOLS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROMOTER REGIONS, GENETIC; RATS; RATS, WISTAR; TANDEM MASS SPECTROMETRY; TRANSCRIPTION INITIATION SITE;

EID: 84903779504     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0099800     Document Type: Article

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