메뉴 건너뛰기




Volumn 18, Issue 8, 2014, Pages 770-778

Non-targeted effects (bystander, abscopal) of external beam radiation therapy: An overview for the clinician;Effets non ciblés (bystander, abscopal) de la radiothérapie externe: Potentielles implications pour le clinicien?

Author keywords

Cellular communication; Distant or abscopal effect, cohort effect; Immunity; Local bystander effect; Long range bystander; Tumor

Indexed keywords

IMMUNOMODULATING AGENT;

EID: 84919333793     PISSN: 12783218     EISSN: 17696658     Source Type: Journal    
DOI: 10.1016/j.canrad.2014.08.004     Document Type: Short Survey
Times cited : (16)

References (75)
  • 1
    • 67649359533 scopus 로고    scopus 로고
    • Systemic effects of local radiotherapy
    • Formenti S.C., Demaria S. Systemic effects of local radiotherapy. Lancet Oncol 2009, 10:718-726.
    • (2009) Lancet Oncol , vol.10 , pp. 718-726
    • Formenti, S.C.1    Demaria, S.2
  • 3
    • 34248545717 scopus 로고    scopus 로고
    • Cancer related fatigue: a focus on breast cancer and Hodgkin's disease survivors
    • Ganz P.A., Bower J.E. Cancer related fatigue: a focus on breast cancer and Hodgkin's disease survivors. Acta Oncol 2007, 46:474-479.
    • (2007) Acta Oncol , vol.46 , pp. 474-479
    • Ganz, P.A.1    Bower, J.E.2
  • 4
    • 84870880129 scopus 로고    scopus 로고
    • Cytokines in radiobiological responses: a review
    • Schaue D., Kachikwu E.L., McBride W.H. Cytokines in radiobiological responses: a review. Radiat Res 2012, 178:505-523.
    • (2012) Radiat Res , vol.178 , pp. 505-523
    • Schaue, D.1    Kachikwu, E.L.2    McBride, W.H.3
  • 5
    • 84881341126 scopus 로고    scopus 로고
    • Cytokine changes in response to radio-/chemotherapeutic treatment in head and neck cancer
    • Reers S., Pfannerstill A.-C., Rades D., Maushagen R., Andratschke M., Pries R., et al. Cytokine changes in response to radio-/chemotherapeutic treatment in head and neck cancer. Anticancer Res 2013, 33:2481-2489.
    • (2013) Anticancer Res , vol.33 , pp. 2481-2489
    • Reers, S.1    Pfannerstill, A.-C.2    Rades, D.3    Maushagen, R.4    Andratschke, M.5    Pries, R.6
  • 6
    • 0014345224 scopus 로고
    • Chromosome damage induced by plasma of x-rayed patients: an indirect effect of x-ray
    • Hollowell J.G., Littlefield L.G. Chromosome damage induced by plasma of x-rayed patients: an indirect effect of x-ray. Proc Soc Exp Biol Med 1968, 129:240-244.
    • (1968) Proc Soc Exp Biol Med , vol.129 , pp. 240-244
    • Hollowell, J.G.1    Littlefield, L.G.2
  • 7
    • 79961098043 scopus 로고    scopus 로고
    • Radiation-induced bystander effects: what are they, and how relevant are they to human radiation exposures?
    • Blyth B.J., Sykes P.J. Radiation-induced bystander effects: what are they, and how relevant are they to human radiation exposures?. Radiat Res 2011, 176:139-157.
    • (2011) Radiat Res , vol.176 , pp. 139-157
    • Blyth, B.J.1    Sykes, P.J.2
  • 8
    • 84919344805 scopus 로고    scopus 로고
    • IRSN, Clamart, [rapport IRSN 2006-74. Disponible en ligne à l'adresse
    • Nénot J.C., Sugier A. Synthèse par l'IRSN des rapports de l'UNSCEAR. Période 2003-2007 2006, IRSN, Clamart, [rapport IRSN 2006-74. Disponible en ligne à l'adresse: http://www.irsn.fr/FR/Larecherche/publications-documentation/collection-ouvrages-IRSN/Documents/IRSN_reference:synthese_rapport_unscear.pdf].
    • (2006) Synthèse par l'IRSN des rapports de l'UNSCEAR. Période 2003-2007
    • Nénot, J.C.1    Sugier, A.2
  • 9
    • 0038290198 scopus 로고
    • Structural changes produced in microspores of Tradescantia by alpha-radiation
    • Kotval J.P., Gray L.H. Structural changes produced in microspores of Tradescantia by alpha-radiation. J Genet 1947, 48:135-154.
    • (1947) J Genet , vol.48 , pp. 135-154
    • Kotval, J.P.1    Gray, L.H.2
  • 10
    • 79953793768 scopus 로고    scopus 로고
    • Radiation-induced non-targeted response: mechanism and potential clinical implications
    • Hei T.K., Zhou H., Chai Y., Ponnaiya B., Ivanov V.N. Radiation-induced non-targeted response: mechanism and potential clinical implications. Curr Mol Pharmacol 2011, 4:96-105.
    • (2011) Curr Mol Pharmacol , vol.4 , pp. 96-105
    • Hei, T.K.1    Zhou, H.2    Chai, Y.3    Ponnaiya, B.4    Ivanov, V.N.5
  • 12
    • 0026454677 scopus 로고
    • Induction of sister chromatid exchanges by extremely low doses of alpha-particles
    • Nagasawa H., Little J.B. Induction of sister chromatid exchanges by extremely low doses of alpha-particles. Cancer Res 1992, 52:6394-6396.
    • (1992) Cancer Res , vol.52 , pp. 6394-6396
    • Nagasawa, H.1    Little, J.B.2
  • 13
    • 0033609082 scopus 로고    scopus 로고
    • Targeted cytoplasmic irradiation with alpha particles induces mutations in mammalian cells
    • Wu L.J., Randers-Pehrson G., Xu A., Waldren C.A., Geard C.R., Yu Z., et al. Targeted cytoplasmic irradiation with alpha particles induces mutations in mammalian cells. Proc Natl Acad Sci U S A 1999, 96:4959-4964.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 4959-4964
    • Wu, L.J.1    Randers-Pehrson, G.2    Xu, A.3    Waldren, C.A.4    Geard, C.R.5    Yu, Z.6
  • 14
    • 0030898609 scopus 로고    scopus 로고
    • Medium from irradiated human epithelial cells but not human fibroblasts reduces the clonogenic survival of unirradiated cells
    • Mothersill C., Seymour C. Medium from irradiated human epithelial cells but not human fibroblasts reduces the clonogenic survival of unirradiated cells. Int J Radiat Biol 1997, 71:421-427.
    • (1997) Int J Radiat Biol , vol.71 , pp. 421-427
    • Mothersill, C.1    Seymour, C.2
  • 15
    • 0031936163 scopus 로고    scopus 로고
    • Cell-cell contact during gamma irradiation is not required to induce a bystander effect in normal human keratinocytes: evidence for release during irradiation of a signal controlling survival into the medium
    • Mothersill C., Seymour C.B. Cell-cell contact during gamma irradiation is not required to induce a bystander effect in normal human keratinocytes: evidence for release during irradiation of a signal controlling survival into the medium. Radiat Res 1998, 149:256-262.
    • (1998) Radiat Res , vol.149 , pp. 256-262
    • Mothersill, C.1    Seymour, C.B.2
  • 17
    • 0030824455 scopus 로고    scopus 로고
    • Alpha particles initiate biological production of superoxide anions and hydrogen peroxide in human cells
    • Narayanan P.K., Goodwin E.H., Lehnert B.E. Alpha particles initiate biological production of superoxide anions and hydrogen peroxide in human cells. Cancer Res 1997, 57:3963-3971.
    • (1997) Cancer Res , vol.57 , pp. 3963-3971
    • Narayanan, P.K.1    Goodwin, E.H.2    Lehnert, B.E.3
  • 18
    • 84857790898 scopus 로고    scopus 로고
    • Cytochrome-c mediated a bystander response dependent on inducible nitric oxide synthase in irradiated hepatoma cells
    • He M., Ye S., Ren R., Dong C., Xie Y., Yuan D., et al. Cytochrome-c mediated a bystander response dependent on inducible nitric oxide synthase in irradiated hepatoma cells. Br J Cancer 2012, 106:889-895.
    • (2012) Br J Cancer , vol.106 , pp. 889-895
    • He, M.1    Ye, S.2    Ren, R.3    Dong, C.4    Xie, Y.5    Yuan, D.6
  • 19
    • 16444382297 scopus 로고    scopus 로고
    • Medium-mediated intercellular communication is involved in bystander responses of X-ray-irradiated normal human fibroblasts
    • Yang H., Asaad N., Held K.D. Medium-mediated intercellular communication is involved in bystander responses of X-ray-irradiated normal human fibroblasts. Oncogene 2005, 24:2096-2103.
    • (2005) Oncogene , vol.24 , pp. 2096-2103
    • Yang, H.1    Asaad, N.2    Held, K.D.3
  • 20
    • 65749108526 scopus 로고    scopus 로고
    • Up-regulation of ROS by mitochondria-dependent bystander signaling contributes to genotoxicity of bystander effects
    • Chen S., Zhao Y., Zhao G., Han W., Bao L., Yu K.N., et al. Up-regulation of ROS by mitochondria-dependent bystander signaling contributes to genotoxicity of bystander effects. Mutat Res 2009, 666:68-73.
    • (2009) Mutat Res , vol.666 , pp. 68-73
    • Chen, S.1    Zhao, Y.2    Zhao, G.3    Han, W.4    Bao, L.5    Yu, K.N.6
  • 21
    • 34250879092 scopus 로고    scopus 로고
    • Cytoplasmic irradiation induces mitochondrial-dependent 53BP1 protein relocalization in irradiated and bystander cells
    • Tartier L., Gilchrist S., Burdak-Rothkamm S., Folkard M., Prise K.M. Cytoplasmic irradiation induces mitochondrial-dependent 53BP1 protein relocalization in irradiated and bystander cells. Cancer Res 2007, 67:5872-5879.
    • (2007) Cancer Res , vol.67 , pp. 5872-5879
    • Tartier, L.1    Gilchrist, S.2    Burdak-Rothkamm, S.3    Folkard, M.4    Prise, K.M.5
  • 22
    • 0242658550 scopus 로고    scopus 로고
    • Oxidative metabolism, gap junctions and the ionizing radiation-induced bystander effect
    • Azzam E.I., de Toledo S.M., Little J.B. Oxidative metabolism, gap junctions and the ionizing radiation-induced bystander effect. Oncogene 2003, 22:7050-7057.
    • (2003) Oncogene , vol.22 , pp. 7050-7057
    • Azzam, E.I.1    de Toledo, S.M.2    Little, J.B.3
  • 23
    • 0031770716 scopus 로고    scopus 로고
    • Intercellular communication is involved in the bystander regulation of gene expression in human cells exposed to very low fluences of alpha particles
    • Azzam E.I., de Toledo S.M., Gooding T., Little J.B. Intercellular communication is involved in the bystander regulation of gene expression in human cells exposed to very low fluences of alpha particles. Radiat Res 1998, 150:497-504.
    • (1998) Radiat Res , vol.150 , pp. 497-504
    • Azzam, E.I.1    de Toledo, S.M.2    Gooding, T.3    Little, J.B.4
  • 24
    • 0035895240 scopus 로고    scopus 로고
    • Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from alpha-particle irradiated to nonirradiated cells
    • Azzam E.I., de Toledo S.M., Little J.B. Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from alpha-particle irradiated to nonirradiated cells. Proc Natl Acad Sci U S A 2001, 98:473-478.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 473-478
    • Azzam, E.I.1    de Toledo, S.M.2    Little, J.B.3
  • 25
    • 80755140180 scopus 로고    scopus 로고
    • Role of connexin43 and ATP in long-range bystander radiation damage and oncogenesis in vivo
    • Mancuso M., Pasquali E., Leonardi S., Rebessi S., Tanori M., Giardullo P., et al. Role of connexin43 and ATP in long-range bystander radiation damage and oncogenesis in vivo. Oncogene 2011, 30:4601-4608.
    • (2011) Oncogene , vol.30 , pp. 4601-4608
    • Mancuso, M.1    Pasquali, E.2    Leonardi, S.3    Rebessi, S.4    Tanori, M.5    Giardullo, P.6
  • 26
    • 33748474948 scopus 로고    scopus 로고
    • Calcium fluxes modulate the radiation-induced bystander responses in targeted glioma and fibroblast cells
    • Shao C., Lyng F.M., Folkard M., Prise K.M. Calcium fluxes modulate the radiation-induced bystander responses in targeted glioma and fibroblast cells. Radiat Res 2006, 166:479-487.
    • (2006) Radiat Res , vol.166 , pp. 479-487
    • Shao, C.1    Lyng, F.M.2    Folkard, M.3    Prise, K.M.4
  • 27
    • 33646052257 scopus 로고    scopus 로고
    • Cellular radiation effects and the bystander response
    • Little J.B. Cellular radiation effects and the bystander response. Mutat Res 2006, 597:113-118.
    • (2006) Mutat Res , vol.597 , pp. 113-118
    • Little, J.B.1
  • 28
    • 0033018216 scopus 로고    scopus 로고
    • Alpha particles induce the production of interleukin-8 by human cells
    • Narayanan P.K., LaRue K.E., Goodwin E.H., Lehnert B.E. Alpha particles induce the production of interleukin-8 by human cells. Radiat Res 1999, 152:57-63.
    • (1999) Radiat Res , vol.152 , pp. 57-63
    • Narayanan, P.K.1    LaRue, K.E.2    Goodwin, E.H.3    Lehnert, B.E.4
  • 29
    • 62349086720 scopus 로고    scopus 로고
    • Death receptor pathways mediate targeted and non-targeted effects of ionizing radiations in breast cancer cells
    • Luce A., Courtin A., Levalois C., Altmeyer-Morel S., Romeo P.-H., Chevillard S., et al. Death receptor pathways mediate targeted and non-targeted effects of ionizing radiations in breast cancer cells. Carcinogenesis 2009, 30:432-439.
    • (2009) Carcinogenesis , vol.30 , pp. 432-439
    • Luce, A.1    Courtin, A.2    Levalois, C.3    Altmeyer-Morel, S.4    Romeo, P.-H.5    Chevillard, S.6
  • 30
    • 0034161938 scopus 로고    scopus 로고
    • Factors underlying the cell growth-related bystander responses to alpha particles
    • Iyer R., Lehnert B.E., Svensson R. Factors underlying the cell growth-related bystander responses to alpha particles. Cancer Res 2000, 60:1290-1298.
    • (2000) Cancer Res , vol.60 , pp. 1290-1298
    • Iyer, R.1    Lehnert, B.E.2    Svensson, R.3
  • 31
    • 26844488765 scopus 로고    scopus 로고
    • Mechanism of radiation-induced bystander effect: role of the cyclooxygenase-2 signaling pathway
    • Zhou H., Ivanov V.N., Gillespie J., Geard C.R., Amundson S.A., Brenner D.J., et al. Mechanism of radiation-induced bystander effect: role of the cyclooxygenase-2 signaling pathway. Proc Natl Acad Sci USA 2005, 102(41):14641-14646.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.41 , pp. 14641-14646
    • Zhou, H.1    Ivanov, V.N.2    Gillespie, J.3    Geard, C.R.4    Amundson, S.A.5    Brenner, D.J.6
  • 32
    • 84874638215 scopus 로고    scopus 로고
    • Radiation-induced bone marrow apoptosis, inflammatory bystander-type signaling and tissue cytotoxicity
    • Mukherjee D., Coates P.J., Rastogi S., Lorimore S.A., Wright E.G. Radiation-induced bone marrow apoptosis, inflammatory bystander-type signaling and tissue cytotoxicity. Int J Radiat Biol 2013, 89:139-146.
    • (2013) Int J Radiat Biol , vol.89 , pp. 139-146
    • Mukherjee, D.1    Coates, P.J.2    Rastogi, S.3    Lorimore, S.A.4    Wright, E.G.5
  • 33
    • 54249143111 scopus 로고    scopus 로고
    • Chromosomal instability in unirradiated hemaopoietic cells induced by macrophages exposed in vivo to ionizing radiation
    • Lorimore S.A., Chrystal J.A., Robinson J.I., Coates P.J., Wright E.G. Chromosomal instability in unirradiated hemaopoietic cells induced by macrophages exposed in vivo to ionizing radiation. Cancer Res 2008, 68:8122-8126.
    • (2008) Cancer Res , vol.68 , pp. 8122-8126
    • Lorimore, S.A.1    Chrystal, J.A.2    Robinson, J.I.3    Coates, P.J.4    Wright, E.G.5
  • 34
    • 0033765546 scopus 로고    scopus 로고
    • Production of a signal by irradiated cells which leads to a response in unirradiated cells characteristic of initiation of apoptosis
    • Lyng F.M., Seymour C.B., Mothersill C. Production of a signal by irradiated cells which leads to a response in unirradiated cells characteristic of initiation of apoptosis. Br J Cancer 2000, 83:1223-1230.
    • (2000) Br J Cancer , vol.83 , pp. 1223-1230
    • Lyng, F.M.1    Seymour, C.B.2    Mothersill, C.3
  • 35
    • 0037439703 scopus 로고    scopus 로고
    • Characterization of a novel epigenetic effect of ionizing radiation: the death-inducing effect
    • Nagar S., Smith L.E., Morgan W.F. Characterization of a novel epigenetic effect of ionizing radiation: the death-inducing effect. Cancer Res 2003, 63:324-328.
    • (2003) Cancer Res , vol.63 , pp. 324-328
    • Nagar, S.1    Smith, L.E.2    Morgan, W.F.3
  • 36
    • 0030835472 scopus 로고    scopus 로고
    • Delayed expression of lethal mutations and genomic instability in the progeny of human epithelial cells that survived in a bystander-killing environment
    • Seymour C.B., Mothersill C. Delayed expression of lethal mutations and genomic instability in the progeny of human epithelial cells that survived in a bystander-killing environment. Radiat Oncol Investig 1997, 5:106-110.
    • (1997) Radiat Oncol Investig , vol.5 , pp. 106-110
    • Seymour, C.B.1    Mothersill, C.2
  • 37
    • 0034862832 scopus 로고    scopus 로고
    • Production of delayed death and neoplastic transformation in CGL1 cells by radiation-induced bystander effects
    • Lewis D.A., Mayhugh B.M., Qin Y., Trott K., Mendonca M.S. Production of delayed death and neoplastic transformation in CGL1 cells by radiation-induced bystander effects. Radiat Res 2001, 156:251-258.
    • (2001) Radiat Res , vol.156 , pp. 251-258
    • Lewis, D.A.1    Mayhugh, B.M.2    Qin, Y.3    Trott, K.4    Mendonca, M.S.5
  • 38
    • 18444399260 scopus 로고    scopus 로고
    • Transplantation for accidental acute high-dose total body neutron- and gamma-radiation exposure
    • Chiba S., Saito A., Ogawa S., Takeuchi K., Kumano K., Seo S., et al. Transplantation for accidental acute high-dose total body neutron- and gamma-radiation exposure. Bone Marrow Transplant 2002, 29:935-939.
    • (2002) Bone Marrow Transplant , vol.29 , pp. 935-939
    • Chiba, S.1    Saito, A.2    Ogawa, S.3    Takeuchi, K.4    Kumano, K.5    Seo, S.6
  • 39
    • 34249315106 scopus 로고    scopus 로고
    • DNA double-strand breaks form in bystander cells after microbeam irradiation of three-dimensional human tissue models
    • Sedelnikova O.A., Nakamura A., Kovalchuk O., Koturbash I., Mitchell S.A., Marino S.A., et al. DNA double-strand breaks form in bystander cells after microbeam irradiation of three-dimensional human tissue models. Cancer Res 2007, 67:4295-4302.
    • (2007) Cancer Res , vol.67 , pp. 4295-4302
    • Sedelnikova, O.A.1    Nakamura, A.2    Kovalchuk, O.3    Koturbash, I.4    Mitchell, S.A.5    Marino, S.A.6
  • 40
    • 31544478262 scopus 로고    scopus 로고
    • The time and spatial effects of bystander response in mammalian cells induced by low dose radiation
    • Hu B., Wu L., Han W., Zhang L., Chen S., Xu A., et al. The time and spatial effects of bystander response in mammalian cells induced by low dose radiation. Carcinogenesis 2006, 27:245-251.
    • (2006) Carcinogenesis , vol.27 , pp. 245-251
    • Hu, B.1    Wu, L.2    Han, W.3    Zhang, L.4    Chen, S.5    Xu, A.6
  • 41
    • 55349111148 scopus 로고    scopus 로고
    • LET-dependent bystander effects caused by irradiation of human prostate carcinoma cells with X rays or alpha particles
    • Anzenberg V., Chandiramani S., Coderre J.A. LET-dependent bystander effects caused by irradiation of human prostate carcinoma cells with X rays or alpha particles. Radiat Res 2008, 170:467-476.
    • (2008) Radiat Res , vol.170 , pp. 467-476
    • Anzenberg, V.1    Chandiramani, S.2    Coderre, J.A.3
  • 42
    • 33744802373 scopus 로고    scopus 로고
    • Inhibitory and stimulatory bystander effects are differentially induced by iodine-125 and iodine-123
    • Kishikawa H., Wang K., Adelstein S.J., Kassis A.I. Inhibitory and stimulatory bystander effects are differentially induced by iodine-125 and iodine-123. Radiat Res 2006, 165:688-694.
    • (2006) Radiat Res , vol.165 , pp. 688-694
    • Kishikawa, H.1    Wang, K.2    Adelstein, S.J.3    Kassis, A.I.4
  • 43
    • 30944438262 scopus 로고    scopus 로고
    • The bystander effect-induced formation of micronucleated cells is inhibited by antioxidants, but the parallel induction of apoptosis and loss of viability are not affected
    • Konopacka M., Rzeszowska-Wolny J. The bystander effect-induced formation of micronucleated cells is inhibited by antioxidants, but the parallel induction of apoptosis and loss of viability are not affected. Mutat Res 2006, 593:32-38.
    • (2006) Mutat Res , vol.593 , pp. 32-38
    • Konopacka, M.1    Rzeszowska-Wolny, J.2
  • 45
    • 84856235426 scopus 로고    scopus 로고
    • Bystander normal human fibroblasts reduce damage response in radiation targeted cancer cells through intercellular ROS level modulation
    • Widel M., Przybyszewski W.M., Cieslar-Pobuda A., Saenko Y.V., Rzeszowska-Wolny J. Bystander normal human fibroblasts reduce damage response in radiation targeted cancer cells through intercellular ROS level modulation. Mutat Res 2012, 731:117-124.
    • (2012) Mutat Res , vol.731 , pp. 117-124
    • Widel, M.1    Przybyszewski, W.M.2    Cieslar-Pobuda, A.3    Saenko, Y.V.4    Rzeszowska-Wolny, J.5
  • 46
    • 33745879774 scopus 로고    scopus 로고
    • A dose threshold for a medium transfer bystander effect for a human skin cell line
    • Liu Z., Mothersill C.E., McNeill F.E., Lyng F.M., Byun S.H., Seymour C.B., et al. A dose threshold for a medium transfer bystander effect for a human skin cell line. Radiat Res 2006, 166(1 Pt 1):19-23.
    • (2006) Radiat Res , vol.166 , Issue.1 , pp. 19-23
    • Liu, Z.1    Mothersill, C.E.2    McNeill, F.E.3    Lyng, F.M.4    Byun, S.H.5    Seymour, C.B.6
  • 48
    • 3843125417 scopus 로고    scopus 로고
    • Bystander effect and adaptive response in C3H 10T1/2 cells
    • Mitchell S.A.M. Bystander effect and adaptive response in C3H 10T1/2 cells. Int J Radiat Biol 2004, 80:465-472.
    • (2004) Int J Radiat Biol , vol.80 , pp. 465-472
    • Mitchell, S.A.M.1
  • 49
    • 58549100663 scopus 로고    scopus 로고
    • The use of microbeams to investigate radiation damage in living cells
    • Folkard M., Prise K.M., Grime G., Kirkby K., Vojnovic B. The use of microbeams to investigate radiation damage in living cells. Appl Radiat Isot 2009, 67:436-439.
    • (2009) Appl Radiat Isot , vol.67 , pp. 436-439
    • Folkard, M.1    Prise, K.M.2    Grime, G.3    Kirkby, K.4    Vojnovic, B.5
  • 51
    • 0035102360 scopus 로고    scopus 로고
    • The bystander effect in radiation oncogenesis: II. A quantitative model
    • Brenner D.J., Little J.B., Sachs R.K. The bystander effect in radiation oncogenesis: II. A quantitative model. Radiat Res 2001, 155:402-408.
    • (2001) Radiat Res , vol.155 , pp. 402-408
    • Brenner, D.J.1    Little, J.B.2    Sachs, R.K.3
  • 52
    • 71749121797 scopus 로고    scopus 로고
    • Ionizing radiation-induced bystander effects, potential targets for modulation of radiotherapy
    • Rzeszowska-Wolny J., Przybyszewski W.M., Widel M. Ionizing radiation-induced bystander effects, potential targets for modulation of radiotherapy. Eur J Pharmacol 2009, 625:156-164.
    • (2009) Eur J Pharmacol , vol.625 , pp. 156-164
    • Rzeszowska-Wolny, J.1    Przybyszewski, W.M.2    Widel, M.3
  • 53
    • 0013071190 scopus 로고
    • Whole body irradiation; radiobiology or medicine?
    • Mole R.H. Whole body irradiation; radiobiology or medicine?. Br J Radiol 1953, 26:234-241.
    • (1953) Br J Radiol , vol.26 , pp. 234-241
    • Mole, R.H.1
  • 54
    • 84912558665 scopus 로고    scopus 로고
    • Abscopal effects of radiation therapy: a clinical review for the radiobiologist
    • Siva S., MacManus M.P., Martin R.F., Martin O.A. Abscopal effects of radiation therapy: a clinical review for the radiobiologist. Cancer Lett 2013, 10.1016/j.canlet.2013.09.018.
    • (2013) Cancer Lett
    • Siva, S.1    MacManus, M.P.2    Martin, R.F.3    Martin, O.A.4
  • 55
    • 0027987169 scopus 로고
    • Spontaneous regression of metastatic renal cell carcinoma following palliative irradiation of the primary tumour
    • MacManus M.P., Harte R.J., Stranex S. Spontaneous regression of metastatic renal cell carcinoma following palliative irradiation of the primary tumour. Ir J Med Sci 1994, 163:461-463.
    • (1994) Ir J Med Sci , vol.163 , pp. 461-463
    • MacManus, M.P.1    Harte, R.J.2    Stranex, S.3
  • 56
    • 12244289275 scopus 로고    scopus 로고
    • Partial volume rat lung irradiation; assessment of early DNA damage in different lung regions and effect of radical scavengers
    • Khan M.A., Van Dyk J., Yeung I.W.T., Hill R.P. Partial volume rat lung irradiation; assessment of early DNA damage in different lung regions and effect of radical scavengers. Radiother Oncol 2003, 66:95-102.
    • (2003) Radiother Oncol , vol.66 , pp. 95-102
    • Khan, M.A.1    Van Dyk, J.2    Yeung, I.W.T.3    Hill, R.P.4
  • 57
    • 0027269561 scopus 로고
    • Radiation-enhanced expression of major histocompatibility complex classI antigen H-2Db in B16 melanoma cells
    • Hauser S.H., Calorini L., Wazer D.E., Gattoni-Celli S. Radiation-enhanced expression of major histocompatibility complex classI antigen H-2Db in B16 melanoma cells. Cancer Res 1993, 53:1952-1955.
    • (1993) Cancer Res , vol.53 , pp. 1952-1955
    • Hauser, S.H.1    Calorini, L.2    Wazer, D.E.3    Gattoni-Celli, S.4
  • 58
    • 45449090985 scopus 로고    scopus 로고
    • Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity
    • Lugade A.A., Sorensen E.W., Gerber S.A., Moran J.P., Frelinger J.G., Lord E.M. Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity. J Immunol 2008, 180:3132-3139.
    • (2008) J Immunol , vol.180 , pp. 3132-3139
    • Lugade, A.A.1    Sorensen, E.W.2    Gerber, S.A.3    Moran, J.P.4    Frelinger, J.G.5    Lord, E.M.6
  • 59
    • 34848857434 scopus 로고    scopus 로고
    • Transforming growth factor-beta and the immune response: implications for anticancer therapy
    • Wrzesinski S.H., Wan Y.Y., Flavell R.A. Transforming growth factor-beta and the immune response: implications for anticancer therapy. Clin Cancer Res 2007, 13(18 Pt 1):5262-5270.
    • (2007) Clin Cancer Res , vol.13 , Issue.18 , pp. 5262-5270
    • Wrzesinski, S.H.1    Wan, Y.Y.2    Flavell, R.A.3
  • 61
    • 0034655262 scopus 로고    scopus 로고
    • CC chemokine receptor-7 on dendritic cells is induced after interaction with apoptotic tumor cells: critical role in migration from the tumor site to draining lymph nodes
    • Hirao M., Onai N., Hiroishi K., Watkins S.C., Matsushima K., Robbins P.D., et al. CC chemokine receptor-7 on dendritic cells is induced after interaction with apoptotic tumor cells: critical role in migration from the tumor site to draining lymph nodes. Cancer Res 2000, 60:2209-2217.
    • (2000) Cancer Res , vol.60 , pp. 2209-2217
    • Hirao, M.1    Onai, N.2    Hiroishi, K.3    Watkins, S.C.4    Matsushima, K.5    Robbins, P.D.6
  • 62
    • 84867911449 scopus 로고    scopus 로고
    • Exposure to ionizing radiation induces the migration of cutaneous dendritic cells by a CCR7-dependent mechanism
    • Cummings R.J., Gerber S.A., Judge J.L., Ryan J.L., Pentland A.P., Lord E.M. Exposure to ionizing radiation induces the migration of cutaneous dendritic cells by a CCR7-dependent mechanism. J Immunol 2012, 189:4247-4257.
    • (2012) J Immunol , vol.189 , pp. 4247-4257
    • Cummings, R.J.1    Gerber, S.A.2    Judge, J.L.3    Ryan, J.L.4    Pentland, A.P.5    Lord, E.M.6
  • 65
    • 0020657530 scopus 로고
    • Abscopal regression following radiotherapy for adenocarcinoma
    • Rees G.J., Ross C.M. Abscopal regression following radiotherapy for adenocarcinoma. Br J Radiol 1983, 56:63-66.
    • (1983) Br J Radiol , vol.56 , pp. 63-66
    • Rees, G.J.1    Ross, C.M.2
  • 66
  • 67
    • 39749126854 scopus 로고    scopus 로고
    • Enhancement of antitumor radiation efficacy and consistent induction of the abscopal effect in mice by ECI301, an active variant of macrophage inflammatory protein-1alpha
    • Shiraishi K., Ishiwata Y., Nakagawa K., Yokochi S., Taruki C., Akuta T., et al. Enhancement of antitumor radiation efficacy and consistent induction of the abscopal effect in mice by ECI301, an active variant of macrophage inflammatory protein-1alpha. Clin Cancer Res 2008, 14:1159-1166.
    • (2008) Clin Cancer Res , vol.14 , pp. 1159-1166
    • Shiraishi, K.1    Ishiwata, Y.2    Nakagawa, K.3    Yokochi, S.4    Taruki, C.5    Akuta, T.6
  • 68
    • 84856838662 scopus 로고    scopus 로고
    • Abscopal regression of antigen disparate tumors by antigen cascade after systemic tumor vaccination in combination with local tumor radiation
    • Hodge J.W., Sharp H.J., Gameiro S.R. Abscopal regression of antigen disparate tumors by antigen cascade after systemic tumor vaccination in combination with local tumor radiation. Cancer Biother Radiopharm 2012, 27:12-22.
    • (2012) Cancer Biother Radiopharm , vol.27 , pp. 12-22
    • Hodge, J.W.1    Sharp, H.J.2    Gameiro, S.R.3
  • 69
    • 69949085196 scopus 로고    scopus 로고
    • Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody
    • Dewan M.Z., Galloway A.E., Kawashima N., Dewyngaert J.K., Babb J.S., Formenti S.C., et al. Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody. Clin Cancer Res 2009, 15:5379-5388.
    • (2009) Clin Cancer Res , vol.15 , pp. 5379-5388
    • Dewan, M.Z.1    Galloway, A.E.2    Kawashima, N.3    Dewyngaert, J.K.4    Babb, J.S.5    Formenti, S.C.6
  • 70
    • 20444406500 scopus 로고    scopus 로고
    • Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor
    • Lugade A.A., Moran J.P., Gerber S.A., Rose R.C., Frelinger J.G., Lord E.M. Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor. J Immunol 2005, 174:7516-7523.
    • (2005) J Immunol , vol.174 , pp. 7516-7523
    • Lugade, A.A.1    Moran, J.P.2    Gerber, S.A.3    Rose, R.C.4    Frelinger, J.G.5    Lord, E.M.6
  • 71
    • 84864977831 scopus 로고    scopus 로고
    • Spontaneous regression of thoracic metastases while progression of brain metastases after stereotactic radiosurgery and stereotactic body radiotherapy for metastatic renal cell carcinoma: abscopal effect prevented by the blood-brain barrier?
    • Ishiyama H., Teh B.S., Ren H., Chiang S., Tann A., Blanco A.I., et al. Spontaneous regression of thoracic metastases while progression of brain metastases after stereotactic radiosurgery and stereotactic body radiotherapy for metastatic renal cell carcinoma: abscopal effect prevented by the blood-brain barrier?. Clin Genitourin Cancer 2012, 10:196-198.
    • (2012) Clin Genitourin Cancer , vol.10 , pp. 196-198
    • Ishiyama, H.1    Teh, B.S.2    Ren, H.3    Chiang, S.4    Tann, A.5    Blanco, A.I.6
  • 72
    • 84964284182 scopus 로고    scopus 로고
    • Role of radiation therapy as immune activator in the era of modern immunotherapy for metastatic malignant melanoma
    • Okwan-Duodu D., Pollack B.P., Lawson D., Khan M.K. Role of radiation therapy as immune activator in the era of modern immunotherapy for metastatic malignant melanoma. Am J Clin Oncol 2014, 10.1097/COC.0b013e3182940dc3.
    • (2014) Am J Clin Oncol
    • Okwan-Duodu, D.1    Pollack, B.P.2    Lawson, D.3    Khan, M.K.4
  • 73
    • 84886944998 scopus 로고    scopus 로고
    • Exploiting the stress response to radiation to sensitize poorly immunogenic tumors to anti-CTLA-4 treatment
    • Demaria S., Pilones K.A., Formenti S.C., Dustin M.L. Exploiting the stress response to radiation to sensitize poorly immunogenic tumors to anti-CTLA-4 treatment. Oncoimmunology 2013, 2:e23127.
    • (2013) Oncoimmunology , vol.2 , pp. e23127
    • Demaria, S.1    Pilones, K.A.2    Formenti, S.C.3    Dustin, M.L.4
  • 75
    • 9244228480 scopus 로고    scopus 로고
    • Neoplastic transformation in vitro after exposure to low doses of mammographic-energy X rays: quantitative and mechanistic aspects
    • Ko S.J., Liao X.-Y., Molloi S., Elmore E., Redpath J.L. Neoplastic transformation in vitro after exposure to low doses of mammographic-energy X rays: quantitative and mechanistic aspects. Radiat Res 2004, 162:646-654.
    • (2004) Radiat Res , vol.162 , pp. 646-654
    • Ko, S.J.1    Liao, X.-Y.2    Molloi, S.3    Elmore, E.4    Redpath, J.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.