Sulforaphane Inhibits IL-1β-Induced Proliferation of Rheumatoid Arthritis Synovial Fibroblasts and the Production of MMPs, COX-2, and PGE2

Inflammation

Volumn 37, Issue 5, 2014, Pages 1496-1503

  Choi, Yun Jung ^a   Lee, Won Seok ^a   Lee, Eun Gyeong ^a   Sung, Myung Soon ^a   Yoo, Wan Hee ^a  

^a Chonbuk National University Medical School and Hospital   (South Korea)

Author keywords

COX; IL 1 ; MMPs; PGE2; rheumatoid arthritis; sulforaphane

Indexed keywords

CHOLECYSTOKININ OCTAPEPTIDE; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; JANUS KINASE; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROSTAGLANDIN E2; STROMELYSIN; SULFORAPHANE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; ISOTHIOCYANIC ACID DERIVATIVE; MMP1 PROTEIN, HUMAN; MMP3 PROTEIN, HUMAN; PTGS2 PROTEIN, HUMAN; SULFORAFAN;

ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FIBROBLAST; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIOCYTE; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; SYNOVIUM;

ARTHRITIS, RHEUMATOID; CELL PROLIFERATION; CELLS, CULTURED; CYCLOOXYGENASE 2; DINOPROSTONE; FIBROBLASTS; HUMANS; INTERLEUKIN-1BETA; ISOTHIOCYANATES; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 3; SYNOVIAL MEMBRANE;

EID: 84918842828     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-014-9875-4     Document Type: Article

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