Synthesis, characterization, and anticancer activity of new quinazoline derivatives against MCF-7 cells

Scientific World Journal

Volumn 2014, Issue , 2014, Pages

  Faraj, Fadhil Lafta ^a,b   Zahedifard, Maryam ^c   Paydar, Mohammadjavad ^a   Looi, Chung Yeng ^a   Majid, Nazia Abdul ^c   Ali, Hapipah Mohd ^a   Ahmad, Noraini ^a   Gwaram, Nura Suleiman ^a   Abdulla, Mahmood Ameen ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

^b UNIVERSITY OF DIYALA   (Iraq)

^c UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

3 (5 BROMO 2 HYDROXY 3 METHOXYBENZYLIDENEAMINO) 2 (5 BROMO 2 HYDROXY 3 METHOXYPHENYL) 2,3 DIHYDROQUINAZOLINE 4(1H)ONE; 3 (5 BROMO 2 HYDROXYBENZYLIDENEAMINO) 2 (5 BROMO 2 HYDROXYPHENYL) 2,3 DIHYDROQUINAZOLINE 4(1H)ONE; ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; ANTINEOPLASTIC AGENT; ASPARTATE AMINOTRANSFERASE; CARBON DIOXIDE; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CHLORIDE; CYTOCHROME C; GAMMA GLUTAMYLTRANSFERASE; GLOBULIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTATE DEHYDROGENASE; POTASSIUM; PROTEIN; QUINAZOLINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; SODIUM; UNCLASSIFIED DRUG; UREA; CASPASE;

ACUTE TOXICITY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANION GAP; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BREAST CANCER CELL LINE; CARBON DIOXIDE BLOOD LEVEL; CELL CYCLE ARREST; CELL CYCLE ASSAY; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CHLORIDE BLOOD LEVEL; CONTROLLED STUDY; DRUG ANALYSIS; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME RELEASE; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GLOBULIN BLOOD LEVEL; HUMAN; HUMAN CELL; IC50; MCF 7 CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; MTT ASSAY; NONHUMAN; POTASSIUM BLOOD LEVEL; PROTEIN BLOOD LEVEL; PROTEIN LOCALIZATION; SODIUM BLOOD LEVEL; UREA BLOOD LEVEL; ABSORPTION; ANIMAL; CARBON NUCLEAR MAGNETIC RESONANCE; CELL CYCLE; CHEMISTRY; DRUG EFFECTS; FLUORESCENCE MICROSCOPY; INFRARED SPECTROPHOTOMETRY; LUMINESCENCE; METABOLISM; MITOCHONDRION; PROTEIN TRANSPORT; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; TIME; TOXICITY TESTING; X RAY CRYSTALLOGRAPHY;

MUS;

ABSORPTION, PHYSICOCHEMICAL; ANIMALS; ANTINEOPLASTIC AGENTS; CARBON-13 MAGNETIC RESONANCE SPECTROSCOPY; CASPASES; CELL CYCLE; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; LUMINESCENCE; MCF-7 CELLS; MICE; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; NF-KAPPA B; PROTEIN TRANSPORT; PROTON MAGNETIC RESONANCE SPECTROSCOPY; QUINAZOLINES; REACTIVE OXYGEN SPECIES; SPECTROPHOTOMETRY, INFRARED; TIME FACTORS; TOXICITY TESTS, ACUTE;

EID: 84918839301     PISSN: 23566140     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1155/2014/212096     Document Type: Article

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