메뉴 건너뛰기




Volumn 20, Issue 4, 2015, Pages 772-783

Inflammation in the pathogenesis of ischemic stroke

Author keywords

IL 17A; Ischemic stroke; Review; Tregs

Indexed keywords

AUTACOID; CYTOKINE;

EID: 84918838539     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/4336     Document Type: Article
Times cited : (43)

References (87)
  • 1
    • 79961209219 scopus 로고    scopus 로고
    • Stroke declines from third to fourth leading cause of death in the United States: Historical perspective and challenges ahead
    • Towfighi A, Saver JL: Stroke declines from third to fourth leading cause of death in the United States: historical perspective and challenges ahead. Stroke 42(8),2351-5 (2011). DOI: 10.1161/STROKEAHA.111.621904
    • (2011) Stroke , vol.42 , Issue.8 , pp. 2351-2355
    • Towfighi, A.1    Saver, J.L.2
  • 4
    • 72149093510 scopus 로고    scopus 로고
    • Mitochondria, oxidative metabolism and cell death in stroke
    • Sims NR, Muyderman H: Mitochondria, oxidative metabolism and cell death in stroke. Biochim Biophys Acta 1802(1), 80-91 (2010). DOI: 10.1016/j.bbadis.2009.09.003
    • (2010) Biochim Biophys Acta , vol.1802 , Issue.1 , pp. 80-91
    • Sims, N.R.1    Muyderman, H.2
  • 5
    • 48849105507 scopus 로고    scopus 로고
    • The cost of cerebral ischaemia
    • Flynn RW, MacWalter RS, Doney AS: The cost of cerebral ischaemia. Neuropharmacology 55(3),250-6 (2008). DOI: 10.1016/j.neuropharm.2008.05.031
    • (2008) Neuropharmacology , vol.55 , Issue.3 , pp. 250-256
    • Flynn, R.W.1    MacWalter, R.S.2    Doney, A.S.3
  • 6
    • 71049180369 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke, therapeutic approaches
    • Lakhan SE, Kirchgessner A, Hofer M: Inflammatory mechanisms in ischemic stroke, therapeutic approaches. J Transl Med 7,97 (2009). DOI: 10.1186/1479-5876-7-97
    • (2009) J Transl Med , vol.7 , pp. 97
    • Lakhan, S.E.1    Kirchgessner, A.2    Hofer, M.3
  • 7
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative disorders
    • Coyle JT, Puttfarcken P: Oxidative stress, glutamate, and neurodegenerative disorders. Science 262(5134),689-95 (1993). DOI: 10.1126/science.7901908
    • (1993) Science , vol.262 , Issue.5134 , pp. 689-695
    • Coyle, J.T.1    Puttfarcken, P.2
  • 9
    • 77949653926 scopus 로고    scopus 로고
    • Biomarkers of hypercoagulability and inflammation in childhood-onset arterial ischemic stroke
    • Bernard TJ, Fenton LZ, Apkon SD, Boada R, Wilkening GN, Wilkinson CC, et al: Biomarkers of hypercoagulability and inflammation in childhood-onset arterial ischemic stroke. J Pediatr 156(4),651-6 (2010). DOI: 10.1016/j.jpeds.2009.10.034
    • (2010) J Pediatr , vol.156 , Issue.4 , pp. 651-656
    • Bernard, T.J.1    Fenton, L.Z.2    Apkon, S.D.3    Boada, R.4    Wilkening, G.N.5    Wilkinson, C.C.6
  • 11
    • 56849129516 scopus 로고    scopus 로고
    • Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice
    • Clausen BH, Lambertsen KL, Babcock AA, Holm TH, Dagnaes-Hansen F, Finsen B: Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice. J Neuroinflammation 5,46 (2008). DOI: 10.1186/1742-2094-5-46
    • (2008) J Neuroinflammation , vol.5 , pp. 46
    • Clausen, B.H.1    Lambertsen, K.L.2    Babcock, A.A.3    Holm, T.H.4    Dagnaes-Hansen, F.5    Finsen, B.6
  • 12
    • 11844282829 scopus 로고    scopus 로고
    • A quantitative study of microglial-macrophage synthesis of tumor necrosis factor during acute and late focal cerebral ischemia in mice
    • Lambertsen KL, Meldgaard M, Ladeby R, Finsen B: A quantitative study of microglial-macrophage synthesis of tumor necrosis factor during acute and late focal cerebral ischemia in mice. J Cereb Blood Flow Metab 25(1),119-35 (2005). DOI: 10.1038/sj.jcbfm.9600014
    • (2005) J Cereb Blood Flow Metab , vol.25 , Issue.1 , pp. 119-135
    • Lambertsen, K.L.1    Meldgaard, M.2    Ladeby, R.3    Finsen, B.4
  • 13
    • 0034771083 scopus 로고    scopus 로고
    • Early TNF-alpha levels correlate with ischaemic stroke severity
    • Zaremba J, Losy J: Early TNF-alpha levels correlate with ischaemic stroke severity. Acta Neurol Scand 104(5),288-95 (2001). DOI: 10.1034/j.1600-0404.2001.00053.x
    • (2001) Acta Neurol Scand , vol.104 , Issue.5 , pp. 288-295
    • Zaremba, J.1    Losy, J.2
  • 15
    • 45849096086 scopus 로고    scopus 로고
    • The impact of inflammation on the pathogenesis and prognosis of ischemic stroke
    • Nakase T, Yamazaki T, Ogura N, Suzuki A, Nagata K: The impact of inflammation on the pathogenesis and prognosis of ischemic stroke. J Neurol Sci 271(1- 2),104-9 (2008). DOI: 10.1016/j.jns.2008.03.020
    • (2008) J Neurol Sci , vol.271 , Issue.1-2 , pp. 104-109
    • Nakase, T.1    Yamazaki, T.2    Ogura, N.3    Suzuki, A.4    Nagata, K.5
  • 16
    • 84874790917 scopus 로고    scopus 로고
    • 3,6'-dithiothalidomide improves experimental stroke outcome by suppressing neuroinflammation
    • Yoon JS, Lee JH, Tweedie D, Mughal MR, Chigurupati S, Greig NH, Mattson MP: 3,6'-dithiothalidomide improves experimental stroke outcome by suppressing neuroinflammation. J Neurosci Res 91(5),671-80 (2013). DOI: 10.1002/jnr.23190
    • (2013) J Neurosci Res , vol.91 , Issue.5 , pp. 671-680
    • Yoon, J.S.1    Lee, J.H.2    Tweedie, D.3    Mughal, M.R.4    Chigurupati, S.5    Greig, N.H.6    Mattson, M.P.7
  • 18
    • 84455161618 scopus 로고    scopus 로고
    • Functional polymorphism of IL-1 alpha and its potential role in obesity in humans and mice
    • Um JY, Rim HK, Kim SJ, Kim HL, Hong SH: Functional polymorphism of IL-1 alpha and its potential role in obesity in humans and mice. PLoS One 6(12),e29524 (2011). DOI: 10.1371/journal.pone.0029524
    • (2011) PLoS One , vol.6 , Issue.12 , pp. e29524
    • Um, J.Y.1    Rim, H.K.2    Kim, S.J.3    Kim, H.L.4    Hong, S.H.5
  • 19
    • 0032536481 scopus 로고    scopus 로고
    • Cerebral vessels express interleukin 1beta after focal cerebral ischemia
    • Zhang Z, Chopp M, Goussev A, Powers C: Cerebral vessels express interleukin 1beta after focal cerebral ischemia. Brain Res 784(1-2),210-7 (1998). DOI: 10.1016/S0006-8993(97)01317-6
    • (1998) Brain Res , vol.784 , Issue.1-2 , pp. 210-217
    • Zhang, Z.1    Chopp, M.2    Goussev, A.3    Powers, C.4
  • 20
    • 0032546904 scopus 로고    scopus 로고
    • Middle cerebral artery occlusion in the rat causes a biphasic production of immunoreactive interleukin-1beta in the cerebral cortex
    • Hillhouse EW, Kida S, Iannotti F: Middle cerebral artery occlusion in the rat causes a biphasic production of immunoreactive interleukin-1beta in the cerebral cortex. Neurosci Lett 249(2-3),177-9 (1998). DOI: 10.1016/S0304-3940(98)00392-9
    • (1998) Neurosci Lett , vol.249 , Issue.2-3 , pp. 177-179
    • Hillhouse, E.W.1    Kida, S.2    Iannotti, F.3
  • 21
    • 0028597074 scopus 로고
    • Concomitant cortical expression of TNF-alpha and IL-1 beta mRNAs follows early response gene expression in transient focal ischemia
    • Wang X, Yue TL, Barone FC, White RF, Gagnon RC, Feuerstein GZ: Concomitant cortical expression of TNF-alpha and IL-1 beta mRNAs follows early response gene expression in transient focal ischemia. Mol Chem Neuropathol 23(2-3),103-14 (1994). DOI: 10.1007/BF02815404
    • (1994) Mol Chem Neuropathol , vol.23 , Issue.2-3 , pp. 103-114
    • Wang, X.1    Yue, T.L.2    Barone, F.C.3    White, R.F.4    Gagnon, R.C.5    Feuerstein, G.Z.6
  • 22
    • 0031894316 scopus 로고    scopus 로고
    • Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice
    • Schielke GP, Yang GY, Shivers BD, Betz AL: Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice. J Cereb Blood Flow Metab 18(2),180-5 (1998). DOI: 10.1097/00004647-199802000-00009
    • (1998) J Cereb Blood Flow Metab , vol.18 , Issue.2 , pp. 180-185
    • Schielke, G.P.1    Yang, G.Y.2    Shivers, B.D.3    Betz, A.L.4
  • 23
    • 0344301879 scopus 로고    scopus 로고
    • Exacerbation of ischemic brain damage by localized striatal injection of interleukin-1beta in the rat
    • Stroemer RP, Rothwell NJ: Exacerbation of ischemic brain damage by localized striatal injection of interleukin-1beta in the rat. J Cereb Blood Flow Metab 18(8),833-9 (1998). DOI: 10.1097/00004647-199808000-00003
    • (1998) J Cereb Blood Flow Metab , vol.18 , Issue.8 , pp. 833-839
    • Stroemer, R.P.1    Rothwell, N.J.2
  • 24
  • 25
    • 34447559410 scopus 로고    scopus 로고
    • Involvement of IL-1beta in acute stress-induced worsening of cerebral ischaemia in rats
    • Caso JR, Moro MA, Lorenzo P, Lizasoain I, Leza JC: Involvement of IL-1beta in acute stress-induced worsening of cerebral ischaemia in rats. Eur Neuropsychopharmacol 17(9),600-7 (2007). DOI: 10.1016/j.euroneuro.2007.02.009
    • (2007) Eur Neuropsychopharmacol , vol.17 , Issue.9 , pp. 600-607
    • Caso, J.R.1    Moro, M.A.2    Lorenzo, P.3    Lizasoain, I.4    Leza, J.C.5
  • 26
    • 0028958354 scopus 로고
    • Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats
    • discussion 681
    • Yamasaki Y, Matsuura N, Shozuhara H, Onodera H, Itoyama Y, Kogure K: Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats. Stroke 26(4),676-80; discussion 681 (1995). DOI: 10.1161/01.STR.26.4.676
    • (1995) Stroke , vol.26 , Issue.4 , pp. 676-680
    • Yamasaki, Y.1    Matsuura, N.2    Shozuhara, H.3    Onodera, H.4    Itoyama, Y.5    Kogure, K.6
  • 27
    • 84863459500 scopus 로고    scopus 로고
    • Blocking interleukin-1 as a novel therapeutic strategy for secondary prevention of cardiovascular events
    • No doi was found
    • Abbate A, Van Tassell BW, Biondi-Zoccai GG: Blocking interleukin-1 as a novel therapeutic strategy for secondary prevention of cardiovascular events. Bio Drugs 26(4),217-33 (2012). No doi was found.
    • (2012) Bio Drugs , vol.26 , Issue.4 , pp. 217-233
    • Abbate, A.1    Van Tassell, B.W.2    Biondi-Zoccai, G.G.3
  • 28
    • 71249164395 scopus 로고    scopus 로고
    • Association of PDE4D and IL-1 gene polymorphism with ischemic stroke in a Han Chinese population
    • Li N, He Z, Xu J, Liu F, Deng S, Zhang H: Association of PDE4D and IL-1 gene polymorphism with ischemic stroke in a Han Chinese population. Brain Res Bull 81(1),38-42 (2010). DOI: 10.1016/j.brainresbull.2009.09.009
    • (2010) Brain Res Bull , vol.81 , Issue.1 , pp. 38-42
    • Li, N.1    He, Z.2    Xu, J.3    Liu, F.4    Deng, S.5    Zhang, H.6
  • 29
    • 84884264398 scopus 로고    scopus 로고
    • Association between Interleukin-1 gene single nucleotide polymorphisms and ischemic stroke classified by TOAST criteria in the Han population of northern China
    • Zhang Z, Liu LJ, Zhang C, Yu YP: Association between Interleukin-1 gene single nucleotide polymorphisms and ischemic stroke classified by TOAST criteria in the Han population of northern China. Biomed Res Int 2013,961039 (2013). DOI: 10.1155/2013/961039
    • (2013) Biomed Res Int , vol.2013 , pp. 961039
    • Zhang, Z.1    Liu, L.J.2    Zhang, C.3    Yu, Y.P.4
  • 30
    • 40949089295 scopus 로고    scopus 로고
    • Variation in inflammation-related genes and risk of incident nonfatal myocardial infarction or ischemic stroke
    • Bis JC, Heckbert SR, Smith NL, Reiner AP, Rice K, Lumley T, et al: Variation in inflammation-related genes and risk of incident nonfatal myocardial infarction or ischemic stroke. Atherosclerosis 198(1),166-73 (2008). DOI: 10.1016/j.atherosclerosis.2007.09.031
    • (2008) Atherosclerosis , vol.198 , Issue.1 , pp. 166-173
    • Bis, J.C.1    Heckbert, S.R.2    Smith, N.L.3    Reiner, A.P.4    Rice, K.5    Lumley, T.6
  • 31
    • 84884669567 scopus 로고    scopus 로고
    • Association of IL-1 receptor antagonist gene VNTR polymorphism with ischemic stroke in the Chinese Uyghur population
    • Tong Y, Han J, Guan X, Lu Z, Miao X, Ye J, et al: Association of IL-1 receptor antagonist gene VNTR polymorphism with ischemic stroke in the Chinese Uyghur population. Biochem Genet 51(9- 10),698-706 (2013). DOI: 10.1007/s10528-013-9599-4
    • (2013) Biochem Genet , vol.51 , Issue.9-10 , pp. 698-706
    • Tong, Y.1    Han, J.2    Guan, X.3    Lu, Z.4    Miao, X.5    Ye, J.6
  • 32
    • 84865588842 scopus 로고    scopus 로고
    • Genetic variation within the interleukin-1 gene cluster and ischemic stroke
    • Olsson S, Holmegaard L, Jood K, Sjögren M, Engström G, Lövkvist H, et al: Genetic variation within the interleukin-1 gene cluster and ischemic stroke. Stroke 43(9),2278-82 (2012). DOI: 10.1161/STROKEAHA.111.647446
    • (2012) Stroke , vol.43 , Issue.9 , pp. 2278-2282
    • Olsson, S.1    Holmegaard, L.2    Jood, K.3    Sjögren, M.4    Engström, G.5    Lövkvist, H.6
  • 33
    • 0030890718 scopus 로고    scopus 로고
    • Gp130 and the interleukin-6 family of cytokines
    • Taga T, Kishimoto T: Gp130 and the interleukin-6 family of cytokines. Annu Rev Immunol 15,797-819 (1997). DOI: 10.1146/annurev.immunol.15.1.797
    • (1997) Annu Rev Immunol , vol.15 , pp. 797-819
    • Taga, T.1    Kishimoto, T.2
  • 34
    • 0029010133 scopus 로고
    • Differential regulation of astrocyte TNF-alpha expression by the cytokines TGF-beta, IL-6 and IL-10
    • Benveniste EN, Tang LP, Law RM: Differential regulation of astrocyte TNF-alpha expression by the cytokines TGF-beta, IL-6 and IL-10. Int J Dev Neurosci 13(3-4),341-9 (1995). DOI: 10.1016/0736-5748(94)00061-7
    • (1995) Int J Dev Neurosci , vol.13 , Issue.3-4 , pp. 341-349
    • Benveniste, E.N.1    Tang, L.P.2    Law, R.M.3
  • 36
    • 44449149285 scopus 로고    scopus 로고
    • Early signaling of inflammation in acute ischemic stroke: Clinical and rheological implications
    • Shenhar-Tsarfaty S, Assayag EB, Bova I, Shopin L, Berliner S, Shapira I, et al: Early signaling of inflammation in acute ischemic stroke: clinical and rheological implications. Thromb Res 122(2),167-73 (2008). DOI: 10.1016/j.thromres.2007.10.019
    • (2008) Thromb Res , vol.122 , Issue.2 , pp. 167-173
    • Shenhar-Tsarfaty, S.1    Assayag, E.B.2    Bova, I.3    Shopin, L.4    Berliner, S.5    Shapira, I.6
  • 38
    • 51649092150 scopus 로고    scopus 로고
    • Ischemic stroke risk, smoking, and the genetics of inflammation in a biracial population: The stroke prevention in young women study
    • Cole JW, Brown DW, Giles WH, Stine OC, O'Connell JR, Mitchell BD, et al: Ischemic stroke risk, smoking, and the genetics of inflammation in a biracial population: the stroke prevention in young women study. Thromb J 6,11 (2008). DOI: 10.1186/1477-9560-6-11
    • (2008) Thromb J , vol.6 , pp. 11
    • Cole, J.W.1    Brown, D.W.2    Giles, W.H.3    Stine, O.C.4    O'Connell, J.R.5    Mitchell, B.D.6
  • 40
    • 74949108768 scopus 로고    scopus 로고
    • IL-17 produced by neutrophils regulates IFN-gamma- mediated neutrophil migration in mouse kidney ischemiareperfusion injury
    • Li L, Huang L, Vergis AL, et al: IL-17 produced by neutrophils regulates IFN-gamma- mediated neutrophil migration in mouse kidney ischemiareperfusion injury. J Clin Invest 120(1),331-342 (2010). DOI: 10.1172/JCI38702
    • (2010) J Clin Invest , vol.120 , Issue.1 , pp. 331-342
    • Li, L.1    Huang, L.2    Vergis, A.L.3
  • 41
    • 79957969252 scopus 로고    scopus 로고
    • Natural killer T cell-derived IL-17 mediates lung ischemiareperfusion injury
    • Sharma AK, LaPar DJ, Zhao Y, et al: Natural killer T cell-derived IL-17 mediates lung ischemiareperfusion injury. Am J Respir Crit Care Med 183(11),1539-1549 (2011). DOI: 10.1164/rccm.201007-1173OC
    • (2011) Am J Respir Crit Care Med , vol.183 , Issue.11 , pp. 1539-1549
    • Sharma, A.K.1    LaPar, D.J.2    Zhao, Y.3
  • 42
    • 79952175153 scopus 로고    scopus 로고
    • Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke
    • Liesz A, Zhou W, Mracsko E, et al: Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke. Brain 134(Pt 3),704-720 (2011). DOI: 10.1093/brain/awr008
    • (2011) Brain , vol.134 , pp. 704-720
    • Liesz, A.1    Zhou, W.2    Mracsko, E.3
  • 43
    • 80555155594 scopus 로고    scopus 로고
    • Increased T cell immunoglobulin and mucin domain 3 positively correlate with systemic IL-17 and TNF-innodataalpha level in the acute phase of ischemic stroke
    • Zhao D, Hou N, Cui M, Liu Y, Liang X, Zhuang X, et al: Increased T cell immunoglobulin and mucin domain 3 positively correlate with systemic IL-17 and TNF-innodataalpha level in the acute phase of ischemic stroke. J Clin Immunol 31(4),719-27 (2011). DOI: 10.1007/s10875-011-9534-6
    • (2011) J Clin Immunol , vol.31 , Issue.4 , pp. 719-727
    • Zhao, D.1    Hou, N.2    Cui, M.3    Liu, Y.4    Liang, X.5    Zhuang, X.6
  • 44
    • 0032584685 scopus 로고    scopus 로고
    • IL-10 reduces rat brain injury following focal stroke
    • Spera PA, Ellison JA, Feuerstein GZ, Barone FC: IL-10 reduces rat brain injury following focal stroke. Neurosci Lett 251(3),189-92 (1998). DOI: 10.1016/S0304-3940(98)00537-0
    • (1998) Neurosci Lett , vol.251 , Issue.3 , pp. 189-192
    • Spera, P.A.1    Ellison, J.A.2    Feuerstein, G.Z.3    Barone, F.C.4
  • 45
    • 0037095746 scopus 로고    scopus 로고
    • Transforming growth factor-beta 1 increases bad phosphorylation and protects neurons against damage
    • No doi was found
    • Zhu Y, Yang GY, Ahlemeyer B, Pang L, Che XM, Culmsee C, et al: Transforming growth factor-beta 1 increases bad phosphorylation and protects neurons against damage. J Neurosci 22(10),3898-909 (2002). No doi was found.
    • (2002) J Neurosci , vol.22 , Issue.10 , pp. 3898-3909
    • Zhu, Y.1    Yang, G.Y.2    Ahlemeyer, B.3    Pang, L.4    Che, X.M.5    Culmsee, C.6
  • 46
    • 70349301512 scopus 로고    scopus 로고
    • Evaluation of the inflammatory response in sera from acute ischemic stroke patients by measurement of IL-2 and IL-10
    • Nayak AR, Kashyap RS, Purohit HJ, Kabra D, Taori GM, Daginawala HF: Evaluation of the inflammatory response in sera from acute ischemic stroke patients by measurement of IL-2 and IL-10. Inflamm Res 58(10),687-91 (2009). DOI: 10.1007/s00011-009-0036-4
    • (2009) Inflamm Res , vol.58 , Issue.10 , pp. 687-691
    • Nayak, A.R.1    Kashyap, R.S.2    Purohit, H.J.3    Kabra, D.4    Taori, G.M.5    Daginawala, H.F.6
  • 47
    • 84875263352 scopus 로고    scopus 로고
    • Prognostic value of neuron specific enolase and IL-10 in ischemic stroke and its correlation with degree of neurological deficit
    • Singh HV, Pandey A, Shrivastava AK, Raizada A, Singh SK, Singh N: Prognostic value of neuron specific enolase and IL-10 in ischemic stroke and its correlation with degree of neurological deficit. Clin Chim Acta 419,136-8 (2013). DOI: 10.1016/j.cca.2013.02.014
    • (2013) Clin Chim Acta , vol.419 , pp. 136-138
    • Singh, H.V.1    Pandey, A.2    Shrivastava, A.K.3    Raizada, A.4    Singh, S.K.5    Singh, N.6
  • 49
    • 13544271161 scopus 로고    scopus 로고
    • Cutting edge: Contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforinindependent mechanism
    • No doi was found
    • Gondek DC, Lu LF, Quezada SA, Sakaguchi S, Noelle RJ: Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforinindependent mechanism. J Immunol 174(4),1783-6 (2005). No doi was found.
    • (2005) J Immunol , vol.174 , Issue.4 , pp. 1783-1786
    • Gondek, D.C.1    Lu, L.F.2    Quezada, S.A.3    Sakaguchi, S.4    Noelle, R.J.5
  • 50
    • 84885947745 scopus 로고    scopus 로고
    • Inflammation-induced catabolism of tryptophan and tyrosine in acute ischemic stroke
    • Ormstad H, Verkerk R, Aass HC, Amthor KF, Sandvik L: Inflammation-induced catabolism of tryptophan and tyrosine in acute ischemic stroke. J Mol Neurosci 51(3),893-902 (2013). DOI: 10.1007/s12031-013-0097-2
    • (2013) J Mol Neurosci , vol.51 , Issue.3 , pp. 893-902
    • Ormstad, H.1    Verkerk, R.2    Aass, H.C.3    Amthor, K.F.4    Sandvik, L.5
  • 51
    • 84899645010 scopus 로고    scopus 로고
    • Relationship of serum interleukin-10 and its genetic variations with ischemic stroke in a chinese general population
    • Xie G, Myint PK, Zaman MJ, Li Y, Zhao L, Shi P, Ren F, Wu Y: Relationship of serum interleukin-10 and its genetic variations with ischemic stroke in a chinese general population. PLoS One 8(9),e74126 (2013). DOI: 10.1371/journal.pone.0074126
    • (2013) PLoS One , vol.8 , Issue.9 , pp. e74126
    • Xie, G.1    Myint, P.K.2    Zaman, M.J.3    Li, Y.4    Zhao, L.5    Shi, P.6    Ren, F.7    Wu, Y.8
  • 52
    • 84860330854 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms (SNPs) of pro-inflammatory/anti-inflammatory and thrombotic/fibrinolytic genes in patients with acute ischemic stroke in relation to TOAST subtype
    • Tuttolomondo A, Di Raimondo D, Forte GI, Casuccio A, Vaccarino L, Scola L, et al: Single nucleotide polymorphisms (SNPs) of pro-inflammatory/anti-inflammatory and thrombotic/fibrinolytic genes in patients with acute ischemic stroke in relation to TOAST subtype. Cytokine 58(3),398-405 (2012). DOI: 10.1016/j.cyto.2012.02.012
    • (2012) Cytokine , vol.58 , Issue.3 , pp. 398-405
    • Tuttolomondo, A.1    Di Raimondo, D.2    Forte, G.I.3    Casuccio, A.4    Vaccarino, L.5    Scola, L.6
  • 53
    • 65549130913 scopus 로고    scopus 로고
    • Temporal and spatial dynamics of cerebral immune cell accumulation in stroke
    • Gelderblom M, Leypoldt F, Steinbach K, et al: Temporal and spatial dynamics of cerebral immune cell accumulation in stroke. Stroke 40(5),1849-1857 (2009). DOI: 10.1161/STROKEAHA.108.534503
    • (2009) Stroke , vol.40 , Issue.5 , pp. 1849-1857
    • Gelderblom, M.1    Leypoldt, F.2    Steinbach, K.3
  • 54
    • 30444459031 scopus 로고    scopus 로고
    • The role of inflammation in CNS injury and disease
    • Lucas SM, Rothwell NJ, Gibson RM. The role of inflammation in CNS injury and disease. Br J Pharmacol 147 Suppl 1,S232-40 (2006). DOI: 10.1038/sj.bjp.0706400
    • (2006) Br J Pharmacol , vol.147 , pp. S232-S240
    • Lucas, S.M.1    Rothwell, N.J.2    Gibson, R.M.3
  • 55
    • 34848828298 scopus 로고    scopus 로고
    • Iron oxide particle-enhanced MRI suggests variability of brain inflammation at early stages after ischemic stroke
    • Saleh A, Schroeter M, Ringelstein A, Hartung HP, Siebler M, Mödder U, et al: Iron oxide particle-enhanced MRI suggests variability of brain inflammation at early stages after ischemic stroke. Stroke 38(10),2733-7 (2007). DOI: 10.1161/STROKEAHA.107.481788
    • (2007) Stroke , vol.38 , Issue.10 , pp. 2733-2737
    • Saleh, A.1    Schroeter, M.2    Ringelstein, A.3    Hartung, H.P.4    Siebler, M.5    Mödder, U.6
  • 56
    • 1842587600 scopus 로고    scopus 로고
    • Astrocyte influences on ischemic neuronal death
    • Swanson RA, Ying W, Kauppinen TM: Astrocyte influences on ischemic neuronal death. Curr Mol Med 4(2),193-205 (2004). DOI: 10.2174/1566524043479185
    • (2004) Curr Mol Med , vol.4 , Issue.2 , pp. 193-205
    • Swanson, R.A.1    Ying, W.2    Kauppinen, T.M.3
  • 57
    • 84875812958 scopus 로고    scopus 로고
    • Spectratype analysis of clonal T cell expansion in murine experimental stroke
    • Liesz A, Karcher S, Veltkamp R: Spectratype analysis of clonal T cell expansion in murine experimental stroke. J Neuroimmunol 257(1-2),46-52 (2013). DOI: 10.1016/j.jneuroim.2013.01.013
    • (2013) J Neuroimmunol , vol.257 , Issue.1-2 , pp. 46-52
    • Liesz, A.1    Karcher, S.2    Veltkamp, R.3
  • 58
    • 33646454450 scopus 로고    scopus 로고
    • Role of T lymphocytes and interferon-gamma in ischemic stroke
    • Yilmaz G, Arumugam TV, Stokes KY, Granger DN: Role of T lymphocytes and interferon-gamma in ischemic stroke. Circulation 113(17),2105-2112 (2006). DOI: 10.1161/ CIRCULATIONAHA.105.593046
    • (2006) Circulation , vol.113 , Issue.17 , pp. 2105-2112
    • Yilmaz, G.1    Arumugam, T.V.2    Stokes, K.Y.3    Granger, D.N.4
  • 59
    • 35448947910 scopus 로고    scopus 로고
    • T- and B-cell-deficient mice with experimental stroke have reduced lesion size and inflammation
    • Hurn PD, Subramanian S, Parker SM, et al: T- and B-cell-deficient mice with experimental stroke have reduced lesion size and inflammation. J Cereb Blood Flow Metab 27(11),1798-1805 (2007). DOI: 10.1038/sj.jcbfm.9600482
    • (2007) J Cereb Blood Flow Metab , vol.27 , Issue.11 , pp. 1798-1805
    • Hurn, P.D.1    Subramanian, S.2    Parker, S.M.3
  • 60
    • 68349160698 scopus 로고    scopus 로고
    • Pivotal role of cerebral interleukin- 17-producing gammadeltaT cells in the delayed phase of ischemic brain injury
    • Shichita T, Sugiyama Y, Ooboshi H, et al: Pivotal role of cerebral interleukin- 17-producing gammadeltaT cells in the delayed phase of ischemic brain injury. Nat Med 15(8),946-950 (2009). DOI: 10.1038/nm.1999
    • (2009) Nat Med , vol.15 , Issue.8 , pp. 946-950
    • Shichita, T.1    Sugiyama, Y.2    Ooboshi, H.3
  • 61
    • 77952557777 scopus 로고    scopus 로고
    • Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation
    • Kleinschnitz C, Schwab N, Kraft P, et al: Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation. Blood 115(18),3835-3842 (2010). DOI: 10.1182/blood-2009-10-249078
    • (2010) Blood , vol.115 , Issue.18 , pp. 3835-3842
    • Kleinschnitz, C.1    Schwab, N.2    Kraft, P.3
  • 62
    • 84868602402 scopus 로고    scopus 로고
    • Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke
    • Gelderblom M, Weymar A, Bernreuther C, Velden J, Arunachalam P, Steinbach K, et al: Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke. Blood 120(18),3793-802 (2012). DOI: 10.1182/blood-2012-02-412726
    • (2012) Blood , vol.120 , Issue.18 , pp. 3793-3802
    • Gelderblom, M.1    Weymar, A.2    Bernreuther, C.3    Velden, J.4    Arunachalam, P.5    Steinbach, K.6
  • 63
    • 59649123881 scopus 로고    scopus 로고
    • Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke
    • Liesz A, Suri-Payer E, Veltkamp C, et al: Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke. Nat Med 15(2),192-199 (2009). DOI: 10.1038/nm.1927
    • (2009) Nat Med , vol.15 , Issue.2 , pp. 192-199
    • Liesz, A.1    Suri-Payer, E.2    Veltkamp, C.3
  • 64
    • 79958265647 scopus 로고    scopus 로고
    • Regulatory B cells limit CNS inflammation and neurologic deficits in murine experimental stroke
    • Ren X, Akiyoshi K, Dziennis S, et al: Regulatory B cells limit CNS inflammation and neurologic deficits in murine experimental stroke. J Neurosci 31(23),8556-8563 (2011). DOI: 10.1523/JNEUROSCI.1623-11.2011
    • (2011) J Neurosci , vol.31 , Issue.23 , pp. 8556-8563
    • Ren, X.1    Akiyoshi, K.2    Dziennis, S.3
  • 65
    • 84891547893 scopus 로고    scopus 로고
    • Adoptive regulatory T-cell therapy protects against cerebral ischemia
    • No doi was found
    • Li P, Gan Y, Sun BL, Zhang F, Lu B, Gao Y, et al: Adoptive regulatory T-cell therapy protects against cerebral ischemia. Ann Neurol 74(3),458-71 (2013). No doi was found.
    • (2013) Ann Neurol , vol.74 , Issue.3 , pp. 458-471
    • Li, P.1    Gan, Y.2    Sun, B.L.3    Zhang, F.4    Lu, B.5    Gao, Y.6
  • 66
    • 84873019070 scopus 로고    scopus 로고
    • Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature
    • Kleinschnitz C, Kraft P, Dreykluft A, Hagedorn I, Göbel K, Schuhmann MK, et al: Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature. Blood 121(4),679-91 (2013). DOI: 10.1182/blood-2012-04-426734
    • (2013) Blood , vol.121 , Issue.4 , pp. 679-691
    • Kleinschnitz, C.1    Kraft, P.2    Dreykluft, A.3    Hagedorn, I.4    Göbel, K.5    Schuhmann, M.K.6
  • 67
    • 84887473041 scopus 로고    scopus 로고
    • Microbleeds in ischemic stroke are associated with lower serum adiponectin and higher soluble E-selectin levels
    • Huang Z, Yin Q, Sun W, Zhu W, Li Y, Liu W, et al: Microbleeds in ischemic stroke are associated with lower serum adiponectin and higher soluble E-selectin levels. J Neurol Sci 334(1-2),83-7 (2013). DOI: 10.1016/j.jns.2013.07.2513
    • (2013) J Neurol Sci , vol.334 , Issue.1-2 , pp. 83-87
    • Huang, Z.1    Yin, Q.2    Sun, W.3    Zhu, W.4    Li, Y.5    Liu, W.6
  • 68
    • 74749108725 scopus 로고    scopus 로고
    • Symmetric dimethylarginine predicts allcause mortality following ischemic stroke
    • Schulze F, Carter AM, Schwedhelm E, Ajjan R, Maas R, von Holten RA, et al: Symmetric dimethylarginine predicts allcause mortality following ischemic stroke. Atherosclerosis 208,518-523 (2010). DOI: 10.1016/j.atherosclerosis.2009.06.039
    • (2010) Atherosclerosis , vol.208 , pp. 518-523
    • Schulze, F.1    Carter, A.M.2    Schwedhelm, E.3    Ajjan, R.4    Maas, R.5    Von Holten, R.A.6
  • 69
    • 33644559016 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine (ADMA) as a risk marker for stroke and TIA in a Swedish population
    • Wanby P, Teerlink T, Brudin L, Brattstrom L, Nilsson I, Palmqvist P, et al: Asymmetric dimethylarginine (ADMA) as a risk marker for stroke and TIA in a Swedish population. Atherosclerosis 185,271-277 (2006). DOI: 10.1016/j.atherosclerosis.2005.06.033
    • (2006) Atherosclerosis , vol.185 , pp. 271-277
    • Wanby, P.1    Teerlink, T.2    Brudin, L.3    Brattstrom, L.4    Nilsson, I.5    Palmqvist, P.6
  • 70
    • 68349147783 scopus 로고    scopus 로고
    • Dimethylarginine levels in cerebrospinal fluid of hyperacute ischemic stroke patients are associated with stroke severity
    • Brouns R, Marescau B, Possemiers I, Sheorajpanday R, De Deyn PP: Dimethylarginine levels in cerebrospinal fluid of hyperacute ischemic stroke patients are associated with stroke severity. Neurochem Res 34,1642-1649 (2009). DOI: 10.1007/s11064-009-9954-3
    • (2009) Neurochem Res , vol.34 , pp. 1642-1649
    • Brouns, R.1    Marescau, B.2    Possemiers, I.3    Sheorajpanday, R.4    De Deyn, P.P.5
  • 71
    • 80053214199 scopus 로고    scopus 로고
    • High plasma dimethylarginine levels are associated with adverse clinical outcome after stroke
    • Worthmann H, Chen S, Martens- Lobenhoffer J, Li N, Deb M, Tryc A, et al: High plasma dimethylarginine levels are associated with adverse clinical outcome after stroke. J Atheroscler Thromb 18,753-761 (2011). DOI: 10.5551/jat.8144
    • (2011) J Atheroscler Thromb , vol.18 , pp. 753-761
    • Worthmann, H.1    Chen, S.2    Martens- Lobenhoffer, J.3    Li, N.4    Deb, M.5    Tryc, A.6
  • 73
    • 33750949797 scopus 로고    scopus 로고
    • High von Willebrand factor levels increase the risk of first ischemic stroke: Influence of ADAMTS13, inflammation, and genetic variability
    • Bongers TN, de Maat MP, van Goor ML, Bhagwanbali V, van Vliet HH, Gómez García EB, et al: High von Willebrand factor levels increase the risk of first ischemic stroke: influence of ADAMTS13, inflammation, and genetic variability. Stroke 37(11),2672-7 (2006). DOI: 10.1161/01.STR.0000244767.39962.f7
    • (2006) Stroke , vol.37 , Issue.11 , pp. 2672-2677
    • Bongers, T.N.1    De Maat, M.P.2    Van Goor, M.L.3    Bhagwanbali, V.4    Van Vliet, H.H.5    Gómez García, E.B.6
  • 74
    • 43049118307 scopus 로고    scopus 로고
    • Evaluation of granulocyte elastase as a sensitive diagnostic parameter of inflammation in first ischemic stroke
    • No doi was found
    • Cojocaru IM, Cojocaru M, Burcin C: Evaluation of granulocyte elastase as a sensitive diagnostic parameter of inflammation in first ischemic stroke. Rom J Intern Med 44(3),317-21 (2006). No doi was found.
    • (2006) Rom J Intern Med , vol.44 , Issue.3 , pp. 317-321
    • Cojocaru, I.M.1    Cojocaru, M.2    Burcin, C.3
  • 75
    • 84893705951 scopus 로고    scopus 로고
    • Peripheral endothelial function and cardiovascular events in high-risk patients
    • Matsuzawa Y, Sugiyama S, Sumida H, Sugamura K, Nozaki T, Ohba K, et al: Peripheral endothelial function and cardiovascular events in high-risk patients. J Am Heart Assoc 2(6),e000426 (2013). DOI: 10.1161/JAHA.113.000426
    • (2013) J Am Heart Assoc , vol.2 , Issue.6 , pp. e000426
    • Matsuzawa, Y.1    Sugiyama, S.2    Sumida, H.3    Sugamura, K.4    Nozaki, T.5    Ohba, K.6
  • 76
    • 84859434576 scopus 로고    scopus 로고
    • Antihypertensive drugs and inflammation in acute ischemic stroke as a predictor factor of future cardiovascular mortality
    • Benbir G, Ince B, Kumral E, Ongen Z, Kultursay H, Tokgozoglu L, et al: Antihypertensive drugs and inflammation in acute ischemic stroke as a predictor factor of future cardiovascular mortality. Inflammation 35(1),65-73 (2012). DOI: 10.1007/s10753-010-9290-4
    • (2012) Inflammation , vol.35 , Issue.1 , pp. 65-73
    • Benbir, G.1    Ince, B.2    Kumral, E.3    Ongen, Z.4    Kultursay, H.5    Tokgozoglu, L.6
  • 77
    • 79551579761 scopus 로고    scopus 로고
    • High sensitivity C-reactive protein (hsCRP) level in cerebrovascular accident (stroke)
    • Mishra PT, Chandra R, Saxena SK, Verma S, Jain R, Bhuyan A: High sensitivity C-reactive protein (hsCRP) level in cerebrovascular accident (stroke). JIACM 11,204-7 (2010).
    • (2010) JIACM , vol.11 , pp. 204-207
    • Mishra, P.T.1    Chandra, R.2    Saxena, S.K.3    Verma, S.4    Jain, R.5    Bhuyan, A.6
  • 78
    • 33646801225 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and stroke
    • Elkind MS: Inflammation, atherosclerosis, and stroke. Neurologist 12,140-8 (2006). DOI: 10.1097/01.nrl.0000215789.70804.b0
    • (2006) Neurologist , vol.12 , pp. 140-148
    • Elkind, M.S.1
  • 79
    • 65949096829 scopus 로고    scopus 로고
    • Inflammatory markers of cardiovascular disease in the elderly
    • No doi was found
    • Ramos AM, Pellanda LC, Gus I, Portal VL: Inflammatory markers of cardiovascular disease in the elderly. Arq Bras Cardiol 92,221-8 (2009). No doi was found.
    • (2009) Arq Bras Cardiol , vol.92 , pp. 221-228
    • Ramos, A.M.1    Pellanda, L.C.2    Gus, I.3    Portal, V.L.4
  • 80
    • 0036314321 scopus 로고    scopus 로고
    • Inflammation, hemostatic markers, and antithrombotic agents in relation to long-term risk of new cardiovascular events in firstever ischemic stroke patients
    • Di Napoli M, Papa F, Villa Pini Stroke Data Bank Investigators: Inflammation, hemostatic markers, and antithrombotic agents in relation to long-term risk of new cardiovascular events in firstever ischemic stroke patients. Stroke 33(7),1763-71 (2002). DOI: 10.1161/01.STR.0000019124.54361.08
    • (2002) Stroke , vol.33 , Issue.7 , pp. 1763-1771
    • Di Napoli, M.1    Papa, F.2
  • 81
    • 16544378315 scopus 로고    scopus 로고
    • Study of some markers of inflammation in atherothrombotic pathogenesis of acute ischemic stroke
    • No doi was found
    • Cojocaru IM, Cojocaru M, Muşuroi C, Drut¸ə A, Bəcanu M: Study of some markers of inflammation in atherothrombotic pathogenesis of acute ischemic stroke. Rom J Intern Med 40(1-4),103-16 (2002). No doi was found.
    • (2002) Rom J Intern Med , vol.40 , Issue.1-4 , pp. 103-116
    • Cojocaru, I.M.1    Cojocaru, M.2    Muşuroi, C.3    Drut¸ə, A.4    Bəcanu, M.5
  • 82
    • 51449103649 scopus 로고    scopus 로고
    • The role of carotid plaque vulnerability and inflammation in the pathogenesis of acute ischemic stroke
    • Ding S, Zhang M, Zhao Y, Chen W, Yao G, Zhang C, et al: The role of carotid plaque vulnerability and inflammation in the pathogenesis of acute ischemic stroke. Am J Med Sci 336(1),27-31 (2008). DOI: 10.1097/MAJ.0b013e31815b60a1
    • (2008) Am J Med Sci , vol.336 , Issue.1 , pp. 27-31
    • Ding, S.1    Zhang, M.2    Zhao, Y.3    Chen, W.4    Yao, G.5    Zhang, C.6
  • 83
    • 77954176108 scopus 로고    scopus 로고
    • Systemic and intraplaque mediators of inflammation are increased in patients symptomatic for ischemic stroke
    • Montecucco F, Lenglet S, Gayet-Ageron A, Bertolotto M, Pelli G, Palombo D, et al: Systemic and intraplaque mediators of inflammation are increased in patients symptomatic for ischemic stroke. Stroke 41(7),1394-404 (2010). DOI: 10.1161/STROKEAHA.110.578369
    • (2010) Stroke , vol.41 , Issue.7 , pp. 1394-1404
    • Montecucco, F.1    Lenglet, S.2    Gayet-Ageron, A.3    Bertolotto, M.4    Pelli, G.5    Palombo, D.6
  • 84
    • 78650173717 scopus 로고    scopus 로고
    • The selective ablation of inflammation in an acute stage of ischemic stroke may be a new strategy to promote neurogenesis
    • Zhou J, Cheng G, Kong R, Gao DK, Zhang X: The selective ablation of inflammation in an acute stage of ischemic stroke may be a new strategy to promote neurogenesis. Med Hypotheses 76(1),1-3 (2011). DOI: 10.1016/j.mehy.2010.07.049
    • (2011) Med Hypotheses , vol.76 , Issue.1 , pp. 1-3
    • Zhou, J.1    Cheng, G.2    Kong, R.3    Gao, D.K.4    Zhang, X.5
  • 85
    • 32944463282 scopus 로고    scopus 로고
    • Kallikrein protects against ischemic stroke by inhibiting apoptosis and inflammation and promoting angiogenesis and neurogenesis
    • Xia CF, Yin H, Yao YY, Borlongan CV, Chao L, Chao J: Kallikrein protects against ischemic stroke by inhibiting apoptosis and inflammation and promoting angiogenesis and neurogenesis. Hum Gene Ther 17(2),206-19 (2006). DOI: 10.1089/hum.2006.17.206
    • (2006) Hum Gene Ther , vol.17 , Issue.2 , pp. 206-219
    • Xia, C.F.1    Yin, H.2    Yao, Y.Y.3    Borlongan, C.V.4    Chao, L.5    Chao, J.6
  • 86
    • 84877136156 scopus 로고    scopus 로고
    • The phosphodiesterase-4 inhibitor rolipram protects from ischemic stroke in mice by reducing blood-brain-barrier damage, inflammation and thrombosis
    • Kraft P, Schwarz T, Göb E, Heydenreich N, Brede M, Meuth SG, et al: The phosphodiesterase-4 inhibitor rolipram protects from ischemic stroke in mice by reducing blood-brain-barrier damage, inflammation and thrombosis. Exp Neurol 247,80-90 (2013). DOI: 10.1016/j.expneurol.2013.03.026
    • (2013) Exp Neurol , vol.247 , pp. 80-90
    • Kraft, P.1    Schwarz, T.2    Göb, E.3    Heydenreich, N.4    Brede, M.5    Meuth, S.G.6
  • 87
    • 84882289777 scopus 로고    scopus 로고
    • Long course hyperbaric oxygen stimulates neurogenesis and attenuates inflammation after ischemic stroke
    • Lee YS, Chio CC, Chang CP, Wang LC, Chiang PM, Niu KC, et al: Long course hyperbaric oxygen stimulates neurogenesis and attenuates inflammation after ischemic stroke. Mediators Inflamm 2013,512978 (2013). DOI: 10.1155/2013/512978
    • (2013) Mediators Inflamm , vol.2013 , pp. 512978
    • Lee, Y.S.1    Chio, C.C.2    Chang, C.P.3    Wang, L.C.4    Chiang, P.M.5    Niu, K.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.