Identification of small proline-rich repeat protein 3 as a novel atheroprotective factor that promotes adaptive akt signaling in vascular smooth muscle cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 12, 2014, Pages 2527-2536

  Segedy, Amanda K ^a   Pyle, Amy L ^d,e   Li, Bin ^a   Zhang, Youmin ^b   Babaev, Vladimir R ^b   Jat, Parmjit ^c   Fazio, Sergio ^a,b   Atkinson, James B ^a,b   Linton, Macrae F ^a,b   Young, Pampee P ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d NATIONWIDE CHILDREN S HOSPITAL   (United States)

^e OHIO STATE UNIVERSITY   (United States)

Author keywords

Akt Proto Oncogene Protein; Atherosclerosis; Muscle, smooth, vascular

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; APOLIPOPROTEIN E; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MYOSIN HEAVY CHAIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROLINE RICH PROTEIN; PROLINE RICH REPEAT PROTEIN 3; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SOMATOMEDIN C; UNCLASSIFIED DRUG; CORNIFIED ENVELOPE LIKE PROLINE RICH PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; AORTA ROOT; APOPTOSIS; ARTICLE; ATHEROMA; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE OVEREXPRESSION; IN VITRO STUDY; MOUSE; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE; ADAPTATION; ANIMAL; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; C57BL MOUSE; DEFICIENCY; DISEASE COURSE; FEMALE; GENETICS; KNOCKOUT MOUSE; MACROPHAGE; MALE; METABOLISM; PATHOLOGY; PHOSPHORYLATION;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; APOLIPOPROTEINS E; APOPTOSIS; ATHEROSCLEROSIS; CELL PROLIFERATION; CELL SURVIVAL; CORNIFIED ENVELOPE PROLINE-RICH PROTEINS; DISEASE PROGRESSION; ENDOTHELIAL CELLS; FEMALE; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCYTES, SMOOTH MUSCLE; PHOSPHORYLATION; PLAQUE, ATHEROSCLEROTIC; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84918821279     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.303644     Document Type: Article

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