Genetic deletion or antibody blockade of α1β1 integrin induces a stable plaque phenotype in ApoE-/- mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 25, Issue 9, 2005, Pages 1917-1924

  Schapira, Kitty ^a   Lutgens, Esther ^a   De Fougerolles, Antonin ^b,c   Sprague, Andrew ^b,c   Roemen, Anouk ^a   Gardner, Humphrey ^b   Koteliansky, Victor ^b,c   Daemen, Mat ^a   Heeneman, Sylvia ^a,d  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b BIOGEN   (United States)

^c ALNYLAM PHARMACEUTICALS   (United States)

^d Department of Pathology ^*  (Netherlands)

Author keywords

Atherosclerosis; Collagen; Extracellular matrix; Integrin; Macrophages

Indexed keywords

APOLIPOPROTEIN E; COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 4; INTEGRIN; VERY LATE ACTIVATION ANTIGEN 1;

ANIMAL CELL; ANTIBODY RESPONSE; ARTICLE; ATHEROSCLEROTIC PLAQUE; CELL INTERACTION; CELL MIGRATION; EXTRACELLULAR MATRIX; GENE DELETION; LEUKOCYTE MIGRATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CONTENT; SMOOTH MUSCLE FIBER;

ANIMALS; ANTIBODIES; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CELL ADHESION; CELL MOVEMENT; COLLAGEN TYPE IV; FEMALE; GENE DELETION; GENE EXPRESSION; INTEGRIN ALPHA1BETA1; LEUKOCYTES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PHENOTYPE;

EID: 24144503329     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000174807.90292.2f     Document Type: Article

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