Hemoglobin α/eNOS coupling at myoendothelial junctions is required for nitric oxide scavenging during vasoconstriction

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 12, 2014, Pages 2594-2600

  Straub, Adam C ^a   Butcher, Joshua T ^b   Billaud, Marie ^b,c   Mutchler, Stephanie M ^b   Artamonov, Mykhaylo V ^c   Nguyen, Anh T ^a   Johnson, Tyler ^b   Best, Angela K ^b   Miller, Megan P ^a   Palmer, Lisa A ^a   Columbus, Linda ^c   Somlyo, Avril V ^c   Le, Thu H ^a   Isakson, Brant E ^b,c  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Endothelial cells; Endothelial nitric oxide synthase; Hemoglobin ; Nitric oxide

Indexed keywords

ANGIOTENSIN II; CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HEMOGLOBIN ALPHA CHAIN; NITRIC OXIDE; PHENYLEPHRINE; NOS3 PROTEIN, MOUSE; RECOMBINANT PROTEIN;

ANIMAL CELL; ANTIBODY LABELING; ARTICLE; BINDING ASSAY; BLOOD PRESSURE; BLOOD PRESSURE REGULATION; BLOOD VESSEL REACTIVITY; BLOOD VESSEL WALL; COMPUTER MODEL; CRYSTAL STRUCTURE; ENDOTHELIUM CELL; EX VIVO STUDY; IN VITRO STUDY; MEAN ARTERIAL PRESSURE; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; THORACODORSAL ARTERY; VASCULAR RESISTANCE; VASOCONSTRICTION; WESTERN BLOTTING; AMINO ACID SEQUENCE; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL JUNCTION; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; CONSERVED SEQUENCE; DEFICIENCY; GENETICS; HUMAN; KNOCKOUT MOUSE; MALE; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS; SMOOTH MUSCLE CELL;

ALPHA-GLOBINS; AMINO ACID SEQUENCE; ANIMALS; BLOOD PRESSURE; CELLS, CULTURED; COMPUTER SIMULATION; CONSERVED SEQUENCE; ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR JUNCTIONS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MYOCYTES, SMOOTH MUSCLE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; VASCULAR RESISTANCE; VASOCONSTRICTION;

EID: 84918809428     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.303974     Document Type: Article

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