Activation of autophagy and paraptosis in retinal ganglion cells after retinal ischemia and reperfusion injury in rats

Experimental and Therapeutic Medicine

Volumn 9, Issue 2, 2015, Pages 476-482

  Wei, Ting ^a   Kang, Qianyan ^a   Ma, Bo ^a   Gao, Shan ^a   Li, Xueying ^a   Liu, Yong ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Autophagy; Paraptosis; Retinal ganglion cells; Retinal ischemia reperfusion injury

Indexed keywords

MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL AGING, CELL DEGENERATION AND CELL SURVIVAL; CELL VACUOLE; CYTOPLASM VESICLE; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM MEMBRANE; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; MALE; MITOCHONDRION; NONHUMAN; PARAPTOSIS; RAT; REPERFUSION INJURY; RETINA BIPOLAR GANGLION CELL; RETINA GANGLION CELL; RETINA ISCHEMIA; STRUCTURE ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY;

EID: 84918806122     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2014.2084     Document Type: Article

References (30)

1. Quigley HA: Glaucoma. Lancet 377: 1367-1377, 2011.
2. Osborne NN, Casson RJ, Wood JP, Chidlow G, Graham M and Melena J: Retinal ischemia: mechanisms of damage and potential therapeutic strategies. Prog Retin Eye Res 23: 91-147, 2004.
3. Kaur C, Foulds WS and Ling EA: Hypoxia-ischemia and retinal ganglion cell damage. Clin Ophthalmol 2: 879-889, 2008.
4. Sun MH, Pang JH, Chen SL, et al: Retinal protection from acute glaucoma-induced ischemia-reperfusion injury through pharmacologic induction of heme oxygenase-1. Invest Ophthalmol Vis Sci 51: 4798-4808, 2010.
5. Yang Z and Klionsky DJ: Eaten alive: A history of macroautophagy. Nat Cell Biol 12: 814-822, 2010.
6. Mizushima N, Levine B, Cuervo AM and Klionsky DJ: Autophagy fights disease through cellular self-digestion. Nature 451: 1069-1075, 2008.
7. Hotchkiss RS, Strasser A, McDunn JE and Swanson PE: Cell death. N Engl J Med 361: 1570-1583, 2009.
8. Hara T, Nakamura K, Matsui M, et al: Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441: 885-889, 2006.
9. Fimia GM, Stoykova A, Romagnoli A, et al: Ambra1 regulates autophagy and development of the nervous system. Nature 447: 1121-1125, 2007.
10. Nijholt DA, de Graaf TR, van Haastert ES, et al: Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: implications for Alzheimer's disease. Cell Death Differ 18: 1071-1081, 2011.
11. Wong E and Cuervo AM: Autophagy gone awry in neurodegenerative diseases. Nat Neurosci 13: 805-811, 2010.
12. Piras A, Gianetto D, Conte D, Bosone A and Vercelli A: Activation of autophagy in a rat model of retinal ischemia following high intraocular pressure. PLoS One 6: e22514, 2011.
13. Park HY, Kim JH and Park CK: Activation of autophagy induces retinal ganglion cell death in a chronic hypertensive glaucoma model. Cell Death Dis 3: e290, 2012.
14. Sperandio S, Poksay KS, Schilling B, Crippen D, Gibson BW and Bredesen DE: Identification of new modulators and protein alterations in non-apoptotic programmed cell death. J Cell Biochem 111: 1401-1412, 2010.
15. Sperandio S, de Belle I and Bredesen DE: An alternative, nonapoptotic form of programmed cell death. Proc Natl Acad Sci USA 97: 14376-14381, 2000.
16. Broker LE, Kruyt FA and Giaccone G: Cell death independent of caspases: a review. Clin Cancer Res 11: 3155-3162, 2005.
17. Wang Y, Li X, Wang L, Ding P, Zhang Y, Han W and Ma D: An alternative form of paraptosis-like cell death, triggered by TAJ/TROY and enhanced by PDCD5 overexpression. J Cell Sci 117: 1525-1532, 2004.
18. Turmaine M, Raza A, Mahal A, Mangiarini L, Bates GP and Davies SW: Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease. Proc Natl Acad Sci USA 97: 8093-8097, 2000.
19. Fombonne J, Padron L, Enjalbert A, Krantic S and Torriglia A: A novel paraptosis pathway involving LEI/L-DNaseII for EGF-induced cell death in somato-lactotrope pituitary cells. Apoptosis 11: 367-375, 2006.
20. Valamanesh F, Torriglia A, Savoldelli M, Gandolphe C, Jeanny JC, BenEzra D and Behar-Cohen F. Glucocorticoids induce retinal toxicity through mechanisms mainly associated with paraptosis. Mol Vis 13: 1746-1757, 2007.
21. Karl R, Singha PK, Venkatachalam MA and Saikumar P: A novel role for MAP1 LC3 in nonautophagic cytoplasmic vacuolation death of cancer cells. Oncogene 28: 2556-2568, 2009.
22. Xie BS, Zhao HC, Yao SK, et al: Autophagy inhibition enhances etoposide-induced cell death in human hepatoma G2 cells. Int J Mol Med 27: 599-606, 2011.
23. Rami A, Langhagen A and Steiger S: Focal cerebral ischemia induces upregulation of Beclin 1 and autophagy-like cell death. Neurobiol Dis 29: 132-141, 2008.
24. Hoa N, Myers M, Douglass T, et al: Molecular mechanisms of paraptosis induction: implications for a non-genetically modified tumor vaccine. PLoS One 4: e4631, 2009.
25. Wang WB, Feng LX, Yue QX, et al: Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90. J Cell Physiol 227: 2196-2206, 2012.
26. Pehar M, O'Riordan KJ, Burns-Cusato M, et al: Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death. Aging Cell 9: 174-190, 2010.
27. Tardito S, Isella C, Medico E, et al: The thioxotriazole copper(II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells. J Biol Chem 284: 24306-24319, 2009.
28. Kim HS and Park CK: Retinal ganglion cell death is delayed by activation of retinal intrinsic cell survival program. Brain Res 1057: 17-28, 2005.
29. Danaila L, Popescu I, Pais V, et al: Apoptosis, paraptosis, necrosis, and cell regeneration in posttraumatic cerebral arteries. Chirurgia (Bucur) 108: 319-324, 2013.
30. Pais V, Danaila L and Pais E: Ultrastructural patterns of the activated cell death programs in the human brain. Ultrastruct Pathol 37: 110-120, 2013.