메뉴 건너뛰기




Volumn 37, Issue 5, 2014, Pages 1705-1717

Orientin Inhibits HMGB1-Induced Inflammatory Responses in HUVECs and in Murine Polymicrobial Sepsis

Author keywords

CLP; flavonoid; HMGB1; sepsis; vascular inflammation

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; ISOORIENTIN; LIPOPOLYSACCHARIDE; ORIENTIN; FLAVONOID; GLUCOSIDE; HMGB1 PROTEIN, HUMAN;

EID: 84918795545     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-014-9899-9     Document Type: Article
Times cited : (42)

References (56)
  • 2
    • 33845885124 scopus 로고    scopus 로고
    • High mobility group box-1 protein induces the migration and activation of human dendritic cells and acts as an alarmin
    • PID: 16966386, COI: 1:CAS:528:DC%2BD2sXktVaiug%3D%3D
    • Yang, D., Q. Chen, H. Yang, K.J. Tracey, M. Bustin, and J.J. Oppenheim. 2007. High mobility group box-1 protein induces the migration and activation of human dendritic cells and acts as an alarmin. Journal of Leukocyte Biology 81: 59–66.
    • (2007) Journal of Leukocyte Biology , vol.81 , pp. 59-66
    • Yang, D.1    Chen, Q.2    Yang, H.3    Tracey, K.J.4    Bustin, M.5    Oppenheim, J.J.6
  • 5
    • 80053617611 scopus 로고    scopus 로고
    • Activated protein C inhibits high mobility group box 1 signaling in endothelial cells
    • PID: 21849480, COI: 1:CAS:528:DC%2BC3MXhtlCgtb3M
    • Bae, J.S., and A.R. Rezaie. 2011. Activated protein C inhibits high mobility group box 1 signaling in endothelial cells. Blood 118: 3952–3959.
    • (2011) Blood , vol.118 , pp. 3952-3959
    • Bae, J.S.1    Rezaie, A.R.2
  • 6
    • 0033538467 scopus 로고    scopus 로고
    • HMG-1 as a late mediator of endotoxin lethality in mice
    • PID: 10398600, COI: 1:CAS:528:DyaK1MXks1Sjtb0%3D
    • Wang, H., O. Bloom, M. Zhang, et al. 1999. HMG-1 as a late mediator of endotoxin lethality in mice. Science 285: 248–251.
    • (1999) Science , vol.285 , pp. 248-251
    • Wang, H.1    Bloom, O.2    Zhang, M.3
  • 7
    • 0035882102 scopus 로고    scopus 로고
    • New EMBO members’ review: the double life of HMGB1 chromatin protein: architectural factor and extracellular signal
    • PID: 11500360, COI: 1:CAS:528:DC%2BD3MXmsVeht7Y%3D
    • Muller, S., P. Scaffidi, B. Degryse, et al. 2001. New EMBO members’ review: the double life of HMGB1 chromatin protein: architectural factor and extracellular signal. EMBO Journal 20: 4337–4340.
    • (2001) EMBO Journal , vol.20 , pp. 4337-4340
    • Muller, S.1    Scaffidi, P.2    Degryse, B.3
  • 8
    • 79953066407 scopus 로고    scopus 로고
    • HMGB1 is a therapeutic target for sterile inflammation and infection
    • PID: 21219181, COI: 1:CAS:528:DC%2BC3MXltlKns78%3D
    • Andersson, U., and K.J. Tracey. 2011. HMGB1 is a therapeutic target for sterile inflammation and infection. Annual Review of Immunology 29: 139–162.
    • (2011) Annual Review of Immunology , vol.29 , pp. 139-162
    • Andersson, U.1    Tracey, K.J.2
  • 9
    • 0028851635 scopus 로고
    • The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system
    • PID: 7592757, COI: 1:CAS:528:DyaK2MXovFyks7s%3D
    • Hori, O., J. Brett, T. Slattery, et al. 1995. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. Journal of Biological Chemistry 270: 25752–25761.
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 25752-25761
    • Hori, O.1    Brett, J.2    Slattery, T.3
  • 10
    • 1542380035 scopus 로고    scopus 로고
    • Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
    • PID: 14660645, COI: 1:CAS:528:DC%2BD2cXhsFaqurc%3D
    • Park, J.S., D. Svetkauskaite, Q. He, et al. 2004. Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. Journal of Biological Chemistry 279: 7370–7377.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 7370-7377
    • Park, J.S.1    Svetkauskaite, D.2    He, Q.3
  • 12
    • 84896281851 scopus 로고    scopus 로고
    • Chemistry and biological activities of flavonoids: an overview
    • PID: 24470791
    • Kumar, S., and A.K. Pandey. 2013. Chemistry and biological activities of flavonoids: an overview. ScientificWorldJournal 2013: 162750.
    • (2013) ScientificWorldJournal , vol.2013 , pp. 162750
    • Kumar, S.1    Pandey, A.K.2
  • 13
    • 0033212836 scopus 로고    scopus 로고
    • Effect of processing on the flavonoid content in buckwheat (Fagopyrum esculentum Moench) grain
    • PID: 10552821, COI: 1:CAS:528:DyaK1MXlvV2jsbs%3D
    • Dietrych-Szostak, D., and W. Oleszek. 1999. Effect of processing on the flavonoid content in buckwheat (Fagopyrum esculentum Moench) grain. Journal of Agricultural and Food Chemistry 47: 4384–4387.
    • (1999) Journal of Agricultural and Food Chemistry , vol.47 , pp. 4384-4387
    • Dietrych-Szostak, D.1    Oleszek, W.2
  • 14
    • 0030738463 scopus 로고    scopus 로고
    • Behavioural effects of Passiflora incarnata L. and its indole alkaloid and flavonoid derivatives and maltol in the mouse
    • PID: 9234160, COI: 1:CAS:528:DyaK2sXks1ans78%3D
    • Soulimani, R., C. Younos, S. Jarmouni, D. Bousta, R. Misslin, and F. Mortier. 1997. Behavioural effects of Passiflora incarnata L. and its indole alkaloid and flavonoid derivatives and maltol in the mouse. Journal of Ethnopharmacology 57: 11–20.
    • (1997) Journal of Ethnopharmacology , vol.57 , pp. 11-20
    • Soulimani, R.1    Younos, C.2    Jarmouni, S.3    Bousta, D.4    Misslin, R.5    Mortier, F.6
  • 15
    • 0036174964 scopus 로고    scopus 로고
    • Antiviral activities of flavonoids and organic acid from Trollius chinensis Bunge
    • PID: 11849843, COI: 1:CAS:528:DC%2BD38Xht1aiurg%3D
    • Li, Y.L., S.C. Ma, Y.T. Yang, S.M. Ye, and P.P. But. 2002. Antiviral activities of flavonoids and organic acid from Trollius chinensis Bunge. Journal of Ethnopharmacology 79: 365–368.
    • (2002) Journal of Ethnopharmacology , vol.79 , pp. 365-368
    • Li, Y.L.1    Ma, S.C.2    Yang, Y.T.3    Ye, S.M.4    But, P.P.5
  • 16
    • 0026319367 scopus 로고
    • Studies on antioxidative activity of some C-glycosylflavones
    • PID: 1824129, COI: 1:CAS:528:DyaK38XktVShurY%3D
    • Budzianowski, J., G. Pakulski, and J. Robak. 1991. Studies on antioxidative activity of some C-glycosylflavones. Polish Journal of Pharmacology and Pharmacy 43: 395–401.
    • (1991) Polish Journal of Pharmacology and Pharmacy , vol.43 , pp. 395-401
    • Budzianowski, J.1    Pakulski, G.2    Robak, J.3
  • 17
    • 84866613367 scopus 로고    scopus 로고
    • Anticoagulant activities of oleanolic acid via inhibition of tissue factor expressions
    • PID: 22831973, COI: 1:CAS:528:DC%2BC38Xht1agtLvN
    • Lee, W., E.J. Yang, S.K. Ku, K.S. Song, and J.S. Bae. 2012. Anticoagulant activities of oleanolic acid via inhibition of tissue factor expressions. BMB Reports 45: 390–395.
    • (2012) BMB Reports , vol.45 , pp. 390-395
    • Lee, W.1    Yang, E.J.2    Ku, S.K.3    Song, K.S.4    Bae, J.S.5
  • 18
    • 84890153581 scopus 로고    scopus 로고
    • Thrombin inhibits HMGB1-mediated proinflammatory signaling responses when endothelial protein C receptor is occupied by its natural ligand
    • PID: 24152910, COI: 1:CAS:528:DC%2BC3sXhvVyitLnF
    • Bae, J.S., and A.R. Rezaie. 2013. Thrombin inhibits HMGB1-mediated proinflammatory signaling responses when endothelial protein C receptor is occupied by its natural ligand. BMB Reports 46: 544–549.
    • (2013) BMB Reports , vol.46 , pp. 544-549
    • Bae, J.S.1    Rezaie, A.R.2
  • 19
    • 0037076787 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression
    • PID: 12065326, COI: 1:CAS:528:DC%2BD38XkvV2gsb0%3D
    • Che, W., N. Lerner-Marmarosh, Q. Huang, et al. 2002. Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression. Circulation Research 90: 1222–1230.
    • (2002) Circulation Research , vol.90 , pp. 1222-1230
    • Che, W.1    Lerner-Marmarosh, N.2    Huang, Q.3
  • 20
    • 84861865524 scopus 로고    scopus 로고
    • Anti-inflammatory functions of purpurogallin in LPS-activated human endothelial cells
    • PID: 22449709, COI: 1:CAS:528:DC%2BC38Xlslyjt7c%3D
    • Kim, T.H., S.K. Ku, I.C. Lee, and J.S. Bae. 2012. Anti-inflammatory functions of purpurogallin in LPS-activated human endothelial cells. BMB Reports 45: 200–205.
    • (2012) BMB Reports , vol.45 , pp. 200-205
    • Kim, T.H.1    Ku, S.K.2    Lee, I.C.3    Bae, J.S.4
  • 21
    • 0027249953 scopus 로고
    • A fluorometric assay for the quantitation of cell adherence to endothelial cells
    • PID: 8354887, COI: 1:CAS:528:DyaK3sXmtVWgsrc%3D
    • Akeson, A.L., and C.W. Woods. 1993. A fluorometric assay for the quantitation of cell adherence to endothelial cells. Journal of Immunological Methods 163: 181–185.
    • (1993) Journal of Immunological Methods , vol.163 , pp. 181-185
    • Akeson, A.L.1    Woods, C.W.2
  • 22
    • 84861664297 scopus 로고    scopus 로고
    • Polyphosphate elicits proinflammatory responses that are counteracted by activated protein C in both cellular and animal models
    • Bae, J.S., W. Lee, and A.R. Rezaie. 2012. Polyphosphate elicits proinflammatory responses that are counteracted by activated protein C in both cellular and animal models. Journal of Thrombosis and Haemostasis 20: 1145–1151.
    • (2012) Journal of Thrombosis and Haemostasis , vol.20 , pp. 1145-1151
    • Bae, J.S.1    Lee, W.2    Rezaie, A.R.3
  • 23
    • 60549095283 scopus 로고    scopus 로고
    • Flavonol-rich RVHxR from Rhus verniciflua Stokes and its major compound fisetin inhibits inflammation-related cytokines and angiogenic factor in rheumatoid arthritic fibroblast-like synovial cells and in vivo models
    • PID: 19111632, COI: 1:CAS:528:DC%2BD1MXit1Klurc%3D
    • Lee, J.D., J.E. Huh, G. Jeon, et al. 2009. Flavonol-rich RVHxR from Rhus verniciflua Stokes and its major compound fisetin inhibits inflammation-related cytokines and angiogenic factor in rheumatoid arthritic fibroblast-like synovial cells and in vivo models. International Immunopharmacology 9: 268–276.
    • (2009) International Immunopharmacology , vol.9 , pp. 268-276
    • Lee, J.D.1    Huh, J.E.2    Jeon, G.3
  • 24
    • 33947544247 scopus 로고    scopus 로고
    • Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: inhibition of cytokine production-dependent mechanism
    • PID: 17320857, COI: 1:CAS:528:DC%2BD2sXjslSksbY%3D
    • Valerio, D.A., T.M. Cunha, N.S. Arakawa, et al. 2007. Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: inhibition of cytokine production-dependent mechanism. European Journal of Pharmacology 562: 155–163.
    • (2007) European Journal of Pharmacology , vol.562 , pp. 155-163
    • Valerio, D.A.1    Cunha, T.M.2    Arakawa, N.S.3
  • 25
    • 9144263639 scopus 로고    scopus 로고
    • Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis
    • PID: 15502843, COI: 1:CAS:528:DC%2BD2cXptVOgtr8%3D
    • Wang, H., H. Liao, M. Ochani, et al. 2004. Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis. Nature Medicine 10: 1216–1221.
    • (2004) Nature Medicine , vol.10 , pp. 1216-1221
    • Wang, H.1    Liao, H.2    Ochani, M.3
  • 26
    • 10844281923 scopus 로고    scopus 로고
    • Activation of human umbilical vein endothelial cells leads to relocation and release of high-mobility group box chromosomal protein 1
    • PID: 15584967, COI: 1:CAS:528:DC%2BD2MXjs1OnsLw%3D
    • Mullins, G.E., J. Sunden-Cullberg, A.S. Johansson, et al. 2004. Activation of human umbilical vein endothelial cells leads to relocation and release of high-mobility group box chromosomal protein 1. Scandinavian Journal of Immunology 60: 566–573.
    • (2004) Scandinavian Journal of Immunology , vol.60 , pp. 566-573
    • Mullins, G.E.1    Sunden-Cullberg, J.2    Johansson, A.S.3
  • 27
    • 27644577000 scopus 로고    scopus 로고
    • Animal models of sepsis: setting the stage
    • PID: 16224456, COI: 1:CAS:528:DC%2BD2MXhtV2kt7fN
    • Buras, J.A., B. Holzmann, and M. Sitkovsky. 2005. Animal models of sepsis: setting the stage. Nature Reviews Drug Discovery 4: 854–865.
    • (2005) Nature Reviews Drug Discovery , vol.4 , pp. 854-865
    • Buras, J.A.1    Holzmann, B.2    Sitkovsky, M.3
  • 28
    • 3242668247 scopus 로고    scopus 로고
    • Bench to bedside: HMGB1-a novel proinflammatory cytokine and potential therapeutic target for septic patients in the emergency department
    • PID: 15289194
    • Sama, A.E., J. D’Amore, M.F. Ward, G. Chen, and H. Wang. 2004. Bench to bedside: HMGB1-a novel proinflammatory cytokine and potential therapeutic target for septic patients in the emergency department. Academic Emergency Medicine 11: 867–873.
    • (2004) Academic Emergency Medicine , vol.11 , pp. 867-873
    • Sama, A.E.1    D’Amore, J.2    Ward, M.F.3    Chen, G.4    Wang, H.5
  • 29
    • 0027486833 scopus 로고
    • Endotoxin-induced arterial endothelial barrier dysfunction assessed by an in vitro model
    • PID: 8306065, COI: 1:CAS:528:DyaK2cXkslOqsw%3D%3D
    • Berman, R.S., J.D. Frew, and W. Martin. 1993. Endotoxin-induced arterial endothelial barrier dysfunction assessed by an in vitro model. British Journal of Pharmacology 110: 1282–1284.
    • (1993) British Journal of Pharmacology , vol.110 , pp. 1282-1284
    • Berman, R.S.1    Frew, J.D.2    Martin, W.3
  • 30
    • 0027445309 scopus 로고
    • Bacterial lipopolysaccharide induces actin reorganization, intercellular gap formation, and endothelial barrier dysfunction in pulmonary vascular endothelial cells: concurrent F-actin depolymerization and new actin synthesis
    • PID: 8408232, COI: 1:CAS:528:DyaK2cXmtVSl
    • Goldblum, S.E., X. Ding, T.W. Brann, and J. Campbell-Washington. 1993. Bacterial lipopolysaccharide induces actin reorganization, intercellular gap formation, and endothelial barrier dysfunction in pulmonary vascular endothelial cells: concurrent F-actin depolymerization and new actin synthesis. Journal of Cellular Physiology 157: 13–23.
    • (1993) Journal of Cellular Physiology , vol.157 , pp. 13-23
    • Goldblum, S.E.1    Ding, X.2    Brann, T.W.3    Campbell-Washington, J.4
  • 31
    • 79651474104 scopus 로고    scopus 로고
    • HMGB1 induces human lung endothelial cell cytoskeletal rearrangement and barrier disruption
    • PID: 21146549, COI: 1:CAS:528:DC%2BC3MXhvVyqsbk%3D
    • Wolfson, R.K., E.T. Chiang, and J.G. Garcia. 2011. HMGB1 induces human lung endothelial cell cytoskeletal rearrangement and barrier disruption. Microvascular Research 81: 189–197.
    • (2011) Microvascular Research , vol.81 , pp. 189-197
    • Wolfson, R.K.1    Chiang, E.T.2    Garcia, J.G.3
  • 33
    • 77954176954 scopus 로고    scopus 로고
    • HMGB1 enhances the proinflammatory activity of lipopolysaccharide by promoting the phosphorylation of MAPK p38 through receptor for advanced glycation end products
    • COI: 1:CAS:528:DC%2BD1MXhtlKhsbnI
    • Qin, Y.H., S.M. Dai, G.S. Tang, et al. 2009. HMGB1 enhances the proinflammatory activity of lipopolysaccharide by promoting the phosphorylation of MAPK p38 through receptor for advanced glycation end products. Journal of Immunology 183: 6244–6250.
    • (2009) Journal of Immunology , vol.183 , pp. 6244-6250
    • Qin, Y.H.1    Dai, S.M.2    Tang, G.S.3
  • 34
    • 57949094797 scopus 로고    scopus 로고
    • Advanced glycation end products depress function of endothelial progenitor cells via p38 and ERK 1/2 mitogen-activated protein kinase pathways
    • PID: 18622638, COI: 1:CAS:528:DC%2BD1MXksVartQ%3D%3D
    • Sun, C., C. Liang, Y. Ren, et al. 2009. Advanced glycation end products depress function of endothelial progenitor cells via p38 and ERK 1/2 mitogen-activated protein kinase pathways. Basic Research in Cardiology 104: 42–49.
    • (2009) Basic Research in Cardiology , vol.104 , pp. 42-49
    • Sun, C.1    Liang, C.2    Ren, Y.3
  • 35
    • 0034867339 scopus 로고    scopus 로고
    • Role of actin filaments in endothelial cell–cell adhesion and membrane stability under fluid shear stress
    • PID: 11512023, COI: 1:CAS:528:DC%2BD3MXlvFWqtrg%3D
    • Schnittler, H.J., S.W. Schneider, H. Raifer, et al. 2001. Role of actin filaments in endothelial cell–cell adhesion and membrane stability under fluid shear stress. Pflügers Archiv 442: 675–687.
    • (2001) Pflügers Archiv , vol.442 , pp. 675-687
    • Schnittler, H.J.1    Schneider, S.W.2    Raifer, H.3
  • 36
    • 0037103274 scopus 로고    scopus 로고
    • Induction of permeability across endothelial cell monolayers by tumor necrosis factor (TNF) occurs via a tissue factor-dependent mechanism: relationship between the procoagulant and permeability effects of TNF
    • PID: 12149215, COI: 1:CAS:528:DC%2BD38Xmt12itb0%3D
    • Friedl, J., M. Puhlmann, D.L. Bartlett, et al. 2002. Induction of permeability across endothelial cell monolayers by tumor necrosis factor (TNF) occurs via a tissue factor-dependent mechanism: relationship between the procoagulant and permeability effects of TNF. Blood 100: 1334–1339.
    • (2002) Blood , vol.100 , pp. 1334-1339
    • Friedl, J.1    Puhlmann, M.2    Bartlett, D.L.3
  • 38
    • 0034698830 scopus 로고    scopus 로고
    • High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes
    • PID: 10952726, COI: 1:CAS:528:DC%2BD3cXlvFemsL0%3D
    • Andersson, U., H. Wang, K. Palmblad, et al. 2000. High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. Journal of Experimental Medicine 192: 565–570.
    • (2000) Journal of Experimental Medicine , vol.192 , pp. 565-570
    • Andersson, U.1    Wang, H.2    Palmblad, K.3
  • 39
    • 84870562887 scopus 로고    scopus 로고
    • Role of high mobility group box 1 in inflammatory disease: focus on sepsis
    • PID: 23054707, COI: 1:CAS:528:DC%2BC38XhsVKrur%2FM
    • Bae, J.S. 2012. Role of high mobility group box 1 in inflammatory disease: focus on sepsis. Archives of Pharmacal Research 35: 1511–1523.
    • (2012) Archives of Pharmacal Research , vol.35 , pp. 1511-1523
    • Bae, J.S.1
  • 40
    • 33745571976 scopus 로고    scopus 로고
    • The immune response in atherosclerosis: a double-edged sword
    • PID: 16778830, COI: 1:CAS:528:DC%2BD28XmtFegsLc%3D
    • Hansson, G.K., and P. Libby. 2006. The immune response in atherosclerosis: a double-edged sword. Nature Reviews Immunology 6: 508–519.
    • (2006) Nature Reviews Immunology , vol.6 , pp. 508-519
    • Hansson, G.K.1    Libby, P.2
  • 41
    • 59149099449 scopus 로고    scopus 로고
    • Induction of high mobility group box 1 release from serotonin-stimulated human umbilical vein endothelial cells
    • PID: 18949384, COI: 1:CAS:528:DC%2BD1cXhsVahsb3O
    • Kawahara, K., T. Hashiguchi, K. Kikuchi, et al. 2008. Induction of high mobility group box 1 release from serotonin-stimulated human umbilical vein endothelial cells. International Journal of Molecular Medicine 22: 639–644.
    • (2008) International Journal of Molecular Medicine , vol.22 , pp. 639-644
    • Kawahara, K.1    Hashiguchi, T.2    Kikuchi, K.3
  • 42
    • 77950223493 scopus 로고    scopus 로고
    • A preferential p110alpha/gamma PI3K inhibitor attenuates experimental inflammation by suppressing the production of proinflammatory mediators in a NF-kappaB-dependent manner
    • COI: 1:CAS:528:DC%2BC3cXksl2qtLY%3D
    • Dagia, N.M., G. Agarwal, D.V. Kamath, et al. 2010. A preferential p110alpha/gamma PI3K inhibitor attenuates experimental inflammation by suppressing the production of proinflammatory mediators in a NF-kappaB-dependent manner. American Journal of Physiology - Cellular Physiology 298: C929–C941.
    • (2010) American Journal of Physiology - Cellular Physiology , vol.298 , pp. C929-C941
    • Dagia, N.M.1    Agarwal, G.2    Kamath, D.V.3
  • 43
    • 84877806447 scopus 로고    scopus 로고
    • High mobility group box-1 promotes the proliferation and migration of hepatic stellate cells via TLR4-dependent signal pathways of PI3K/Akt and JNK
    • PID: 23696886, COI: 1:CAS:528:DC%2BC3sXosFGjsbs%3D
    • Wang, F.P., L. Li, J. Li, J.Y. Wang, L.Y. Wang, and W. Jiang. 2013. High mobility group box-1 promotes the proliferation and migration of hepatic stellate cells via TLR4-dependent signal pathways of PI3K/Akt and JNK. PLoS One 8: e64373.
    • (2013) PLoS One , vol.8 , pp. e64373
    • Wang, F.P.1    Li, L.2    Li, J.3    Wang, J.Y.4    Wang, L.Y.5    Jiang, W.6
  • 44
    • 0032559561 scopus 로고    scopus 로고
    • Inhibition of nuclear factor-kappaB-mediated adhesion molecule expression in human endothelial cells
    • PID: 9486659, COI: 1:CAS:528:DyaK1cXhtlaqur4%3D
    • Lockyer, J.M., J.S. Colladay, W.L. Alperin-Lea, T. Hammond, and A.J. Buda. 1998. Inhibition of nuclear factor-kappaB-mediated adhesion molecule expression in human endothelial cells. Circulation Research 82: 314–320.
    • (1998) Circulation Research , vol.82 , pp. 314-320
    • Lockyer, J.M.1    Colladay, J.S.2    Alperin-Lea, W.L.3    Hammond, T.4    Buda, A.J.5
  • 45
    • 0027365599 scopus 로고
    • Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells
    • PID: 7691889, COI: 1:CAS:528:DyaK2cXisVymsQ%3D%3D
    • Marui, N., M.K. Offermann, R. Swerlick, et al. 1993. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. Journal of Clinical Investigation 92: 1866–1874.
    • (1993) Journal of Clinical Investigation , vol.92 , pp. 1866-1874
    • Marui, N.1    Offermann, M.K.2    Swerlick, R.3
  • 46
    • 78149478401 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale
    • PID: 20959622, COI: 1:CAS:528:DC%2BC3cXhsFSqtbjL
    • Rose, B.A., T. Force, and Y. Wang. 2010. Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. Physiological Reviews 90: 1507–1546.
    • (2010) Physiological Reviews , vol.90 , pp. 1507-1546
    • Rose, B.A.1    Force, T.2    Wang, Y.3
  • 47
    • 33645461206 scopus 로고    scopus 로고
    • High mobility group box 1 protein interacts with multiple Toll-like receptors
    • COI: 1:CAS:528:DC%2BD28Xjt1Slu7g%3D
    • Park, J.S., F. Gamboni-Robertson, Q. He, et al. 2006. High mobility group box 1 protein interacts with multiple Toll-like receptors. American Journal of Physiology - Cellular Physiology 290: C917–C924.
    • (2006) American Journal of Physiology - Cellular Physiology , vol.290 , pp. C917-C924
    • Park, J.S.1    Gamboni-Robertson, F.2    He, Q.3
  • 48
    • 74449089862 scopus 로고    scopus 로고
    • Targeting HMGB1 in inflammation
    • PID: 19948257, COI: 1:CAS:528:DC%2BC3cXpslWnsg%3D%3D
    • Yang, H., and K.J. Tracey. 2010. Targeting HMGB1 in inflammation. Biochimica et Biophysica Acta 1799: 149–156.
    • (2010) Biochimica et Biophysica Acta , vol.1799 , pp. 149-156
    • Yang, H.1    Tracey, K.J.2
  • 49
    • 35349009132 scopus 로고    scopus 로고
    • Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-kappaB activation
    • PID: 17923528, COI: 1:CAS:528:DC%2BD2sXhtFOntbzP
    • Palumbo, R., B.G. Galvez, T. Pusterla, et al. 2007. Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-kappaB activation. Journal of Cell Biology 179: 33–40.
    • (2007) Journal of Cell Biology , vol.179 , pp. 33-40
    • Palumbo, R.1    Galvez, B.G.2    Pusterla, T.3
  • 50
    • 0037180768 scopus 로고    scopus 로고
    • The immunopathogenesis of sepsis
    • PID: 12490963, COI: 1:CAS:528:DC%2BD38XpsFygtbo%3D
    • Cohen, J. 2002. The immunopathogenesis of sepsis. Nature 420: 885–891.
    • (2002) Nature , vol.420 , pp. 885-891
    • Cohen, J.1
  • 51
    • 79952025567 scopus 로고    scopus 로고
    • Curcumin—the paradigm of a multi-target natural compound with applications in cancer prevention and treatment
    • COI: 1:CAS:528:DC%2BC3cXhslGit7k%3D
    • Teiten, M.H., S. Eifes, M. Dicato, and M. Diederich. 2010. Curcumin—the paradigm of a multi-target natural compound with applications in cancer prevention and treatment. Toxins (Basel) 2: 128–162.
    • (2010) Toxins (Basel) , vol.2 , pp. 128-162
    • Teiten, M.H.1    Eifes, S.2    Dicato, M.3    Diederich, M.4
  • 52
    • 33748072117 scopus 로고    scopus 로고
    • Mechanisms of mortality in early and late sepsis
    • PID: 16926416, COI: 1:CAS:528:DC%2BD28Xpt1Sls74%3D
    • Xiao, H., J. Siddiqui, and D.G. Remick. 2006. Mechanisms of mortality in early and late sepsis. Infection and Immunity 74: 5227–5235.
    • (2006) Infection and Immunity , vol.74 , pp. 5227-5235
    • Xiao, H.1    Siddiqui, J.2    Remick, D.G.3
  • 54
    • 0023491364 scopus 로고
    • Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia
    • PID: 3317066, COI: 1:CAS:528:DyaL1cXlsVSktg%3D%3D
    • Tracey, K.J., Y. Fong, D.G. Hesse, et al. 1987. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature 330: 662–664.
    • (1987) Nature , vol.330 , pp. 662-664
    • Tracey, K.J.1    Fong, Y.2    Hesse, D.G.3
  • 55
    • 0018964280 scopus 로고
    • Sepsis and septic shock—a review of laboratory models and a proposal
    • PID: 6997619, COI: 1:STN:280:DyaL3M%2FhtVyisA%3D%3D
    • Wichterman, K.A., A.E. Baue, and I.H. Chaudry. 1980. Sepsis and septic shock—a review of laboratory models and a proposal. Journal of Surgical Research 29: 189–201.
    • (1980) Journal of Surgical Research , vol.29 , pp. 189-201
    • Wichterman, K.A.1    Baue, A.E.2    Chaudry, I.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.