ECM1 promotes the Warburg effect through EGF-mediated activation of PKM2

Cellular Signalling

Volumn 27, Issue 2, 2015, Pages 228-235

  Lee, Kyung min ^a   Nam, Keesoo ^a   Oh, Sunhwa ^a   Lim, Juyeon ^a   Lee, Taehoon ^b   Shin, Incheol ^a  

^a Hanyang University   (South Korea)

^b NovaCell Technology Inc   (South Korea)

Author keywords

ECM1; GLUT1; LDHA; PKM2; Warburg effect

Indexed keywords

EPIDERMAL GROWTH FACTOR; EXTRACELLULAR MATRIX PROTEIN 1; GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE A; MITOGEN ACTIVATED PROTEIN KINASE; PYRUVATE KINASE; PYRUVATE KINASE M2; SCLEROPROTEIN; SERINE; TRASTUZUMAB; UNCLASSIFIED DRUG; EARLY GROWTH RESPONSE FACTOR 1; ECM1 PROTEIN, HUMAN; EGR1 PROTEIN, HUMAN; GLUCOSE; ISOENZYME; LACTATE DEHYDROGENASE 5; MESSENGER RNA; SMALL INTERFERING RNA;

ARTICLE; BREAST CANCER CELL LINE; CELL METABOLISM; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TANDEM MASS SPECTROMETRY; UPREGULATION; WARBURG EFFECT; ANTAGONISTS AND INHIBITORS; GENETICS; GLYCOLYSIS; METABOLISM; PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

CELL LINE, TUMOR; EARLY GROWTH RESPONSE PROTEIN 1; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR MATRIX PROTEINS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; GLYCOLYSIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; ISOENZYMES; L-LACTATE DEHYDROGENASE; PHOSPHORYLATION; PYRUVATE KINASE; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 84918790206     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2014.11.004     Document Type: Article

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