Inflammation-Induced Drug Release by using a pH-Responsive Gas-Generating Hollow-Microsphere System for the Treatment of Osteomyelitis

Advanced Healthcare Materials

Volumn 3, Issue 11, 2014, Pages 1854-1861

  Chung, Ming Fan ^a   Chia, Wei Tso ^b   Liu, Hung Yi ^a   Hsiao, Chun Wen ^a   Hsiao, Hsu Chan ^a   Yang, Chih Man ^b   Sung, Hsing Wen ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Anti inflammation; Inflammatory diseases; Local drug delivery; Smart carriers; Stimuli responsive materials

Indexed keywords

ANTIBIOTICS; BONE CEMENT; CALCIUM PHOSPHATE; CARBON DIOXIDE; MICROSPHERES; PATHOLOGY; SODIUM BICARBONATE; TARGETED DRUG DELIVERY; UNLOADING;

ANTI-BACTERIAL ACTIVITY; ANTI-INFLAMMATION; ANTIBIOTIC CONCENTRATION; HISTOLOGICAL EXAMINATION; INFLAMMATORY DISEASE; LOCAL DRUG DELIVERY; POLY(D ,L LACTIC CO GLYCOLIC ACID) (PLGA); STIMULI-RESPONSIVE MATERIALS;

CONTROLLED DRUG DELIVERY;

BONE CEMENT; CALCIUM PHOSPHATE; DICHLOROMETHANE; POLYGLACTIN; POLYVINYL ALCOHOL; VANCOMYCIN; ANTIINFECTIVE AGENT; CARBON DIOXIDE; DELAYED RELEASE FORMULATION; DRUG CARRIER; GAS; LACTIC ACID; MICROSPHERE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ACIDITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ARTICLE; BONE PROSTHESIS; BONE TISSUE; DEBRIDEMENT; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; DRUG RELEASE; DRUG RESPONSE; ENCAPSULATION; HISTOLOGY; MATERIAL STATE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROFLUIDICS; NONHUMAN; OSTEOMYELITIS; PARTICLE SIZE; PH; PRIORITY JOURNAL; TABLET COMPRESSION; THICKNESS; ANIMAL; CHEMISTRY; DELAYED RELEASE FORMULATION; GAS; INFLAMMATION; PHARMACOLOGY; RABBIT;

ANIMALS; ANTI-BACTERIAL AGENTS; BONE CEMENTS; CALCIUM PHOSPHATES; CARBON DIOXIDE; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG LIBERATION; GASES; HYDROGEN-ION CONCENTRATION; INFLAMMATION; LACTIC ACID; MICROSPHERES; OSTEOMYELITIS; POLYGLYCOLIC ACID; RABBITS; VANCOMYCIN;

EID: 84918782651     PISSN: 21922640     EISSN: 21922659     Source Type: Journal    
DOI: 10.1002/adhm.201400158     Document Type: Article

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