-
1
-
-
68849120875
-
The potential impact of tumour biology on improved clinical practice for medulloblastoma: progress towards biologically driven clinical trials
-
Pizer BL, Clifford SC: The potential impact of tumour biology on improved clinical practice for medulloblastoma: progress towards biologically driven clinical trials. Br J Neurosurg 2009, 23(4):364-375. 10.1080/02688690903121807
-
(2009)
Br J Neurosurg
, vol.23
, Issue.4
, pp. 364-375
-
-
Pizer, B.L.1
Clifford, S.C.2
-
2
-
-
84867869131
-
Concurrent cyclophosphamide and craniospinal radiotherapy for pediatric high-risk embryonal brain tumors
-
Campen CJ, Dearlove J, Partap S, Murphy P, Gibbs IC, Dahl GV, Fisher PG: Concurrent cyclophosphamide and craniospinal radiotherapy for pediatric high-risk embryonal brain tumors. J Neurooncol 2012, 110(2):287-291. 10.1007/s11060-012-0969-2
-
(2012)
J Neurooncol
, vol.110
, Issue.2
, pp. 287-291
-
-
Campen, C.J.1
Dearlove, J.2
Partap, S.3
Murphy, P.4
Gibbs, I.C.5
Dahl, G.V.6
Fisher, P.G.7
-
3
-
-
84866532813
-
Hyperfractionated Versus Conventional Radiotherapy Followed by Chemotherapy in Standard-Risk Medulloblastoma: Results From the Randomized Multicenter HIT-SIOP PNET 4 Trial
-
Lannering B, Rutkowski S, Doz F, Pizer B, Gustafsson G, Navajas A, Massimino M, Reddingius R, Benesch M, Carrie C: Hyperfractionated Versus Conventional Radiotherapy Followed by Chemotherapy in Standard-Risk Medulloblastoma: Results From the Randomized Multicenter HIT-SIOP PNET 4 Trial. J Clin Oncol 2012, 30(26):3187-3193. 10.1200/JCO.2011.39.8719
-
(2012)
J Clin Oncol
, vol.30
, Issue.26
, pp. 3187-3193
-
-
Lannering, B.1
Rutkowski, S.2
Doz, F.3
Pizer, B.4
Gustafsson, G.5
Navajas, A.6
Massimino, M.7
Reddingius, R.8
Benesch, M.9
Carrie, C.10
-
4
-
-
0031680298
-
Atypical teratoid/rhabdoid tumor of the central nervous system: a highly malignant tumor of infancy and childhood frequently mistaken for medulloblastoma: a Pediatric Oncology Group study
-
Burger PC, Yu I, Tihan T, Friedman HS, Strother DR, Kepner JL, Duffner PK, Kun LE, Perlman EJ: Atypical teratoid/rhabdoid tumor of the central nervous system: a highly malignant tumor of infancy and childhood frequently mistaken for medulloblastoma: a Pediatric Oncology Group study. Am J Surg Pathol 1998, 22(9):1083-1092. 10.1097/00000478-199809000-00007
-
(1998)
Am J Surg Pathol
, vol.22
, Issue.9
, pp. 1083-1092
-
-
Burger, P.C.1
Yu, I.2
Tihan, T.3
Friedman, H.S.4
Strother, D.R.5
Kepner, J.L.6
Duffner, P.K.7
Kun, L.E.8
Perlman, E.J.9
-
5
-
-
33745431175
-
Current therapy for medulloblastoma
-
Gottardo NG, Gajjar A: Current therapy for medulloblastoma. Curr Treat Options Neurol 2006, 8(4):319-334. 10.1007/s11940-006-0022-x
-
(2006)
Curr Treat Options Neurol
, vol.8
, Issue.4
, pp. 319-334
-
-
Gottardo, N.G.1
Gajjar, A.2
-
6
-
-
14844331808
-
Outcome for patients with metastatic (M2-3) medulloblastoma treated with SIOP/UKCCSG PNET-3 chemotherapy
-
Taylor RE, Bailey CC, Robinson KJ, Weston CL, Walker DA, Ellison D, Ironside J, Pizer BL, Lashford LS: Outcome for patients with metastatic (M2-3) medulloblastoma treated with SIOP/UKCCSG PNET-3 chemotherapy. Eur J Cancer (Oxford, England: 1990) 2005, 41(5):727-734. doi:10.1016/j.ejca.2004.12.017 10.1016/j.ejca.2004.12.017
-
(2005)
Eur J Cancer (Oxford, England: 1990)
, vol.41
, Issue.5
, pp. 727-734
-
-
Taylor, R.E.1
Bailey, C.C.2
Robinson, K.J.3
Weston, C.L.4
Walker, D.A.5
Ellison, D.6
Ironside, J.7
Pizer, B.L.8
Lashford, L.S.9
-
7
-
-
0033050817
-
Metastasis stage, adjuvant treatment, and residual tumor are prognostic factors for medulloblastoma in children: conclusions from the Children's Cancer Group 921 randomized phase III study
-
Zeltzer PM, Boyett JM, Finlay JL, Albright AL, Rorke LB, Milstein JM, Allen JC, Stevens KR, Stanley P, Li H: Metastasis stage, adjuvant treatment, and residual tumor are prognostic factors for medulloblastoma in children: conclusions from the Children's Cancer Group 921 randomized phase III study. J Clin Oncol 1999, 17(3):832-832.
-
(1999)
J Clin Oncol
, vol.17
, Issue.3
, pp. 832-832
-
-
Zeltzer, P.M.1
Boyett, J.M.2
Finlay, J.L.3
Albright, A.L.4
Rorke, L.B.5
Milstein, J.M.6
Allen, J.C.7
Stevens, K.R.8
Stanley, P.9
Li, H.10
-
8
-
-
59149102350
-
Hyperfractionated accelerated radiotherapy in the Milan strategy for metastatic medulloblastoma
-
Gandola L, Massimino M, Cefalo G, Solero C, Spreafico F, Pecori E, Riva D, Collini P, Pignoli E, Giangaspero F: Hyperfractionated accelerated radiotherapy in the Milan strategy for metastatic medulloblastoma. J Clin Oncol 2009, 27(4):566-571.
-
(2009)
J Clin Oncol
, vol.27
, Issue.4
, pp. 566-571
-
-
Gandola, L.1
Massimino, M.2
Cefalo, G.3
Solero, C.4
Spreafico, F.5
Pecori, E.6
Riva, D.7
Collini, P.8
Pignoli, E.9
Giangaspero, F.10
-
9
-
-
84871996797
-
Survival and secondary tumors in children with medulloblastoma receiving radiotherapy and adjuvant chemotherapy: results of Children's Oncology Group trial A9961
-
Packer RJ, Zhou T, Holmes E, Vezina G, Gajjar A: Survival and secondary tumors in children with medulloblastoma receiving radiotherapy and adjuvant chemotherapy: results of Children's Oncology Group trial A9961. Neuro Oncol 2013, 15(1):97-103. 10.1093/neuonc/nos267
-
(2013)
Neuro Oncol
, vol.15
, Issue.1
, pp. 97-103
-
-
Packer, R.J.1
Zhou, T.2
Holmes, E.3
Vezina, G.4
Gajjar, A.5
-
10
-
-
0037842140
-
Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 Study
-
Taylor RE, Bailey CC, Robinson K, Weston CL, Ellison D, Ironside J, Lucraft H, Gilbertson R, Tait DM, Walker DA: Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 Study. J Clin Oncol 2003, 21(8):1581-1591. 10.1200/JCO.2003.05.116
-
(2003)
J Clin Oncol
, vol.21
, Issue.8
, pp. 1581-1591
-
-
Taylor, R.E.1
Bailey, C.C.2
Robinson, K.3
Weston, C.L.4
Ellison, D.5
Ironside, J.6
Lucraft, H.7
Gilbertson, R.8
Tait, D.M.9
Walker, D.A.10
-
11
-
-
0342614892
-
Postoperative neoadjuvant chemotherapy before radiotherapy as compared to immediate radiotherapy followed by maintenance chemotherapy in the treatment of medulloblastoma in childhood: results of the German prospective randomized trial HIT'91
-
Kortmann RD, Kühl J, Timmermann B, Mittler U, Urban C, Budach V, Richter E, Willich N, Flentje M, Berthold F: Postoperative neoadjuvant chemotherapy before radiotherapy as compared to immediate radiotherapy followed by maintenance chemotherapy in the treatment of medulloblastoma in childhood: results of the German prospective randomized trial HIT'91. Int J Radiat Oncol Biol Phys 2000, 46(2):269-279. 10.1016/S0360-3016(99)00369-7
-
(2000)
Int J Radiat Oncol Biol Phys
, vol.46
, Issue.2
, pp. 269-279
-
-
Kortmann, R.D.1
Kühl, J.2
Timmermann, B.3
Mittler, U.4
Urban, C.5
Budach, V.6
Richter, E.7
Willich, N.8
Flentje, M.9
Berthold, F.10
-
12
-
-
84886726351
-
High-risk medulloblastoma: a Pediatric Oncology Group randomized trial of chemotherapy Before or after radiation therapy (POG 9031)
-
Tarbell NJ, Friedman H, Polkinghorn WR, Yock T, Zhou T, Chen Z, Burger P, Barnes P, Kun L: High-risk medulloblastoma: a Pediatric Oncology Group randomized trial of chemotherapy Before or after radiation therapy (POG 9031). J Clin Oncol 2013, 31(23):2936-2941. 10.1200/JCO.2012.43.9984
-
(2013)
J Clin Oncol
, vol.31
, Issue.23
, pp. 2936-2941
-
-
Tarbell, N.J.1
Friedman, H.2
Polkinghorn, W.R.3
Yock, T.4
Zhou, T.5
Chen, Z.6
Burger, P.7
Barnes, P.8
Kun, L.9
-
13
-
-
31544446902
-
Outcome of medulloblastoma in children: long-term complications and quality of life
-
Ribi K, Relly C, Landolt M, Alber F, Boltshauser E, Grotzer M: Outcome of medulloblastoma in children: long-term complications and quality of life. Neuropediatrics 2005, 36(6):357-365. 10.1055/s-2005-872880
-
(2005)
Neuropediatrics
, vol.36
, Issue.6
, pp. 357-365
-
-
Ribi, K.1
Relly, C.2
Landolt, M.3
Alber, F.4
Boltshauser, E.5
Grotzer, M.6
-
14
-
-
64049087816
-
Long-term outcome and clinical prognostic factors in children with medulloblastoma treated in the prospective randomised multicentre trial HIT '91
-
HoffK, Hinkes B, Gerber NU, Deinlein F, Mittler U, Urban C, Benesch M, Warmuth-Metz M, Soerensen N, Zwiener I: Long-term outcome and clinical prognostic factors in children with medulloblastoma treated in the prospective randomised multicentre trial HIT '91. Eur J Cancer 2009, 45(7):1209-1217. 10.1016/j.ejca.2009.01.015
-
(2009)
Eur J Cancer
, vol.45
, Issue.7
, pp. 1209-1217
-
-
Hoff, K.1
Hinkes, B.2
Gerber, N.U.3
Deinlein, F.4
Mittler, U.5
Urban, C.6
Benesch, M.7
Warmuth-Metz, M.8
Soerensen, N.9
Zwiener, I.10
-
15
-
-
33748660920
-
Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma
-
Packer RJ, Gajjar A, Vezina G, Rorke-Adams L, Burger PC, Robertson PL, Bayer L, LaFond D, Donahue BR, Marymont MAH: Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma. J Clin Oncol 2006, 24(25):4202-4208. 10.1200/JCO.2006.06.4980
-
(2006)
J Clin Oncol
, vol.24
, Issue.25
, pp. 4202-4208
-
-
Packer, R.J.1
Gajjar, A.2
Vezina, G.3
Rorke-Adams, L.4
Burger, P.C.5
Robertson, P.L.6
Bayer, L.7
LaFond, D.8
Donahue, B.R.9
Marymont, M.A.H.10
-
16
-
-
71249117569
-
Primary postoperative chemotherapy without radiotherapy for treatment of brain tumours other than ependymoma in children under 3 years: results of the first UKCCSG/SIOP CNS 9204 trial
-
Grundy R, Wilne S, Robinson K, Ironside J, Cox T, Chong W, Michalski A, Campbell R, Bailey C, Thorp N: Primary postoperative chemotherapy without radiotherapy for treatment of brain tumours other than ependymoma in children under 3 years: results of the first UKCCSG/SIOP CNS 9204 trial. Eur J Cancer 2010, 46(1):120-133. 10.1016/j.ejca.2009.09.013
-
(2010)
Eur J Cancer
, vol.46
, Issue.1
, pp. 120-133
-
-
Grundy, R.1
Wilne, S.2
Robinson, K.3
Ironside, J.4
Cox, T.5
Chong, W.6
Michalski, A.7
Campbell, R.8
Bailey, C.9
Thorp, N.10
-
17
-
-
53549111626
-
Medulloblastoma: new insights into biology and treatment
-
Pizer B, Clifford S: Medulloblastoma: new insights into biology and treatment. Arch Dis Child Educ Pract Ed 2008, 93(5):137-144. 10.1136/adc.2007.136655
-
(2008)
Arch Dis Child Educ Pract Ed
, vol.93
, Issue.5
, pp. 137-144
-
-
Pizer, B.1
Clifford, S.2
-
18
-
-
33749044182
-
Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial
-
Gajjar A, Chintagumpala M, Ashley D, Kellie S, Kun LE, Merchant TE, Woo S, Wheeler G, Ahern V, Krasin MJ: Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial. Lancet Oncol 2006, 7(10):813-820. 10.1016/S1470-2045(06)70867-1
-
(2006)
Lancet Oncol
, vol.7
, Issue.10
, pp. 813-820
-
-
Gajjar, A.1
Chintagumpala, M.2
Ashley, D.3
Kellie, S.4
Kun, L.E.5
Merchant, T.E.6
Woo, S.7
Wheeler, G.8
Ahern, V.9
Krasin, M.J.10
-
19
-
-
67649116468
-
Outcome for metastatic (M+) medulloblastoma (MB) treated with carboplatin during craniospinal radiotherapy (CSRT) followed by cyclophosphamide (CPM) and vincristine (VCR): Preliminary results of COG 99701
-
Jakacki R, Burger P, Zhou T, Holmes E, Packer R, Goldwein J, Mehta M, Pollack I: Outcome for metastatic (M+) medulloblastoma (MB) treated with carboplatin during craniospinal radiotherapy (CSRT) followed by cyclophosphamide (CPM) and vincristine (VCR): Preliminary results of COG 99701. J Clin Oncol 2007, 25(18S):2017.
-
(2007)
J Clin Oncol
, vol.25
, Issue.18
, pp. 2017
-
-
Jakacki, R.1
Burger, P.2
Zhou, T.3
Holmes, E.4
Packer, R.5
Goldwein, J.6
Mehta, M.7
Pollack, I.8
-
20
-
-
84876693211
-
Response to bevacizumab, irinotecan, and temozolomide in children with relapsed medulloblastoma: a multi-institutional experience
-
Aguilera D, Mazewski C, Fangusaro J, MacDonald TJ, McNall-Knapp RY, Hayes LL, Kim S, Castellino RC: Response to bevacizumab, irinotecan, and temozolomide in children with relapsed medulloblastoma: a multi-institutional experience. Childs Nerv Syst 2013, 29(4):589-596. doi:10.1007/s00381-012-2013-4 10.1007/s00381-012-2013-4
-
(2013)
Childs Nerv Syst
, vol.29
, Issue.4
, pp. 589-596
-
-
Aguilera, D.1
Mazewski, C.2
Fangusaro, J.3
MacDonald, T.J.4
McNall-Knapp, R.Y.5
Hayes, L.L.6
Kim, S.7
Castellino, R.C.8
-
21
-
-
84856698901
-
Temozolomide in relapsed pediatric brain tumors: 14 cases from a single center
-
Akyüz C, Demir HA, Varan A, Yalçin B, Kutluk T, Büyükpamukçu M: Temozolomide in relapsed pediatric brain tumors: 14 cases from a single center. Childs Nerv Syst 2012, 28(1):111-115. 10.1007/s00381-011-1561-3
-
(2012)
Childs Nerv Syst
, vol.28
, Issue.1
, pp. 111-115
-
-
Akyüz, C.1
Demir, H.A.2
Varan, A.3
Yalçin, B.4
Kutluk, T.5
Büyükpamukçu, M.6
-
22
-
-
80455125814
-
Reirradiation and concomitant metronomic temozolomide: an efficient combination for local control in medulloblastoma disease
-
Padovani L, Andre N, Gentet JC, Figarella Branger D, Scavarda D, Verschuur A, Chinot O, Cowen D, Muracciole X: Reirradiation and concomitant metronomic temozolomide: An efficient combination for local control in medulloblastoma disease J Pediatr Hematol Oncol 2011, 33(8):600. 10.1097/MPH.0b013e3182331eaf
-
(2011)
J Pediatr Hematol Oncol
, vol.33
, Issue.8
, pp. 600
-
-
Padovani, L.1
Andre, N.2
Gentet, J.C.3
Figarella Branger, D.4
Scavarda, D.5
Verschuur, A.6
Chinot, O.7
Cowen, D.8
Muracciole, X.9
-
23
-
-
62449200068
-
Embryonal neural tumours and cell death
-
Johnsen JI, Kogner P, Albihn A, Henriksson MA: Embryonal neural tumours and cell death. Apoptosis 2009, 14(4):424-438. doi:10.1007/s10495-009-0325-y 10.1007/s10495-009-0325-y
-
(2009)
Apoptosis
, vol.14
, Issue.4
, pp. 424-438
-
-
Johnsen, J.I.1
Kogner, P.2
Albihn, A.3
Henriksson, M.A.4
-
24
-
-
20044371594
-
Treatment of early childhood medulloblastoma by postoperative chemotherapy alone
-
Rutkowski S, Bode U, Deinlein F, Ottensmeier H, Warmuth-Metz M, Soerensen N, Graf N, Emser A, Pietsch T, WolffJEA: Treatment of early childhood medulloblastoma by postoperative chemotherapy alone. N Engl J Med 2005, 352(10):978-986. 10.1056/NEJMoa042176
-
(2005)
N Engl J Med
, vol.352
, Issue.10
, pp. 978-986
-
-
Rutkowski, S.1
Bode, U.2
Deinlein, F.3
Ottensmeier, H.4
Warmuth-Metz, M.5
Soerensen, N.6
Graf, N.7
Emser, A.8
Pietsch, T.9
Wolff, J.E.A.10
-
25
-
-
22944436550
-
Treatment of medulloblastoma with postoperative chemotherapy alone: an SFOP prospective trial in young children
-
Grill J, Sainte-Rose C, Jouvet A, Gentet JC, Lejars O, Frappaz D, Doz F, Rialland X, Pichon F, Bertozzi AI: Treatment of medulloblastoma with postoperative chemotherapy alone: an SFOP prospective trial in young children. Lancet Oncol 2005, 6(8):573-580. 10.1016/S1470-2045(05)70252-7
-
(2005)
Lancet Oncol
, vol.6
, Issue.8
, pp. 573-580
-
-
Grill, J.1
Sainte-Rose, C.2
Jouvet, A.3
Gentet, J.C.4
Lejars, O.5
Frappaz, D.6
Doz, F.7
Rialland, X.8
Pichon, F.9
Bertozzi, A.I.10
-
26
-
-
65949119515
-
Treatment of early childhood medulloblastoma by postoperative chemotherapy and deferred radiotherapy
-
Rutkowski S, Gerber NU, Von HoffK, Gnekow A, Bode U, Graf N, Berthold F, Henze G, WolffJEA, Warmuth-Metz M: Treatment of early childhood medulloblastoma by postoperative chemotherapy and deferred radiotherapy. Neuro Oncol 2009, 11(2):201-210.
-
(2009)
Neuro Oncol
, vol.11
, Issue.2
, pp. 201-210
-
-
Rutkowski, S.1
Gerber, N.U.2
Von Hoff, K.3
Gnekow, A.4
Bode, U.5
Graf, N.6
Berthold, F.7
Henze, G.8
Wolff, J.E.A.9
Warmuth-Metz, M.10
-
27
-
-
33644775686
-
Targeting multidrug resistance in cancer
-
Szakács G, Paterson JK, Ludwig JA, Booth-Genthe C, Gottesman MM: Targeting multidrug resistance in cancer. Nat Rev Drug Discov 2006, 5(3):219-234. 10.1038/nrd1984
-
(2006)
Nat Rev Drug Discov
, vol.5
, Issue.3
, pp. 219-234
-
-
Szakács, G.1
Paterson, J.K.2
Ludwig, J.A.3
Booth-Genthe, C.4
Gottesman, M.M.5
-
28
-
-
0029552544
-
Multidrug resistance gene expression in childhood medulloblastoma: correlation with clinical outcome and DNA ploidy in 29 patients
-
Chou PM, Reyes-Mugica M, Barquin N, Yasuda T, Tan X, Tomita T: Multidrug resistance gene expression in childhood medulloblastoma: correlation with clinical outcome and DNA ploidy in 29 patients. Pediatr Neurosurg 1995, 23(6):283-292. 10.1159/000120984
-
(1995)
Pediatr Neurosurg
, vol.23
, Issue.6
, pp. 283-292
-
-
Chou, P.M.1
Reyes-Mugica, M.2
Barquin, N.3
Yasuda, T.4
Tan, X.5
Tomita, T.6
-
29
-
-
0030810103
-
Immunohistochemical expression of P-glycoprotein and glutathione S-transferases in cerebral gliomas and response to chemotherapy
-
von Bossanyi P, Diete S, Dietzmann K, Warich-Kirches M, Kirches E: Immunohistochemical expression of P-glycoprotein and glutathione S-transferases in cerebral gliomas and response to chemotherapy. Acta Neuropathol 1997, 94(6):605-611. 10.1007/s004010050756
-
(1997)
Acta Neuropathol
, vol.94
, Issue.6
, pp. 605-611
-
-
von Bossanyi, P.1
Diete, S.2
Dietzmann, K.3
Warich-Kirches, M.4
Kirches, E.5
-
30
-
-
79951605709
-
Pediatric brain tumor cancer stem cells: cell cycle dynamics, DNA repair, and etoposide extrusion
-
Hussein D, Punjaruk W, Storer LCD, Shaw L, Ottoman R, Peet A, Miller S, Bandopadhyay G, Heath R, Kumari R: Pediatric brain tumor cancer stem cells: cell cycle dynamics, DNA repair, and etoposide extrusion. Neuro Oncol 2011, 13(1):70-83. 10.1093/neuonc/noq144
-
(2011)
Neuro Oncol
, vol.13
, Issue.1
, pp. 70-83
-
-
Hussein, D.1
Punjaruk, W.2
Storer, L.C.D.3
Shaw, L.4
Ottoman, R.5
Peet, A.6
Miller, S.7
Bandopadhyay, G.8
Heath, R.9
Kumari, R.10
-
31
-
-
84862925785
-
Temozolomide: mechanisms of action, repair and resistance
-
Zhang J, Stevens M, Bradshaw T: Temozolomide: mechanisms of action, repair and resistance. Curr Mol Pharmacol 2012, 5(1):102. 10.2174/1874467211205010102
-
(2012)
Curr Mol Pharmacol
, vol.5
, Issue.1
, pp. 102
-
-
Zhang, J.1
Stevens, M.2
Bradshaw, T.3
-
32
-
-
79959954645
-
Expression of O 6-methylguanine-DNA methyltransferase in childhood medulloblastoma
-
Faoro D, von Bueren AO, Shalaby T, Sciuscio D, Hürlimann ML, Arnold L, Gerber NU, Haybaeck J, Mittelbronn M, Rutkowski S: Expression of O 6-methylguanine-DNA methyltransferase in childhood medulloblastoma. J Neurooncol 2011, 103(1):59-69. 10.1007/s11060-010-0366-7
-
(2011)
J Neurooncol
, vol.103
, Issue.1
, pp. 59-69
-
-
Faoro, D.1
von Bueren, A.O.2
Shalaby, T.3
Sciuscio, D.4
Hürlimann, M.L.5
Arnold, L.6
Gerber, N.U.7
Haybaeck, J.8
Mittelbronn, M.9
Rutkowski, S.10
-
33
-
-
84867397241
-
Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours
-
von Bueren AO, Bacolod MD, Hagel C, Heinimann K, Fedier A, Kordes U, Pietsch T, Koster J, Grotzer MA, Friedman HS, Marra G, Kool M, Rutkowski S: Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours. Br J Cancer 2012, 107(8):1399-1408. doi:10.1038/bjc.2012.403 10.1038/bjc.2012.403
-
(2012)
Br J Cancer
, vol.107
, Issue.8
, pp. 1399-1408
-
-
von Bueren, A.O.1
Bacolod, M.D.2
Hagel, C.3
Heinimann, K.4
Fedier, A.5
Kordes, U.6
Pietsch, T.7
Koster, J.8
Grotzer, M.A.9
Friedman, H.S.10
Marra, G.11
Kool, M.12
Rutkowski, S.13
-
34
-
-
0023160388
-
Antitumour imidazotetrazines-XV: Role of guanine O6 alkylation in the mechanism of cytotoxicity of imidazotetrazinones
-
Tisdale MJ: Antitumour imidazotetrazines-XV: Role of guanine O6 alkylation in the mechanism of cytotoxicity of imidazotetrazinones. Biochem Pharmacol 1987, 36(4):457-462. 10.1016/0006-2952(87)90351-0
-
(1987)
Biochem Pharmacol
, vol.36
, Issue.4
, pp. 457-462
-
-
Tisdale, M.J.1
-
35
-
-
78149469318
-
Central nervous system penetration and enhancement of temozolomide activity in childhood medulloblastoma models by poly (ADP-ribose) polymerase inhibitor AG-014699
-
Daniel R, Rozanska A, Mulligan E, Drew Y, Thomas H, Castelbuono D, Hostomsky Z, Plummer E, Tweddle D, Boddy A: Central nervous system penetration and enhancement of temozolomide activity in childhood medulloblastoma models by poly (ADP-ribose) polymerase inhibitor AG-014699. Br J Cancer 2010, 103(10):1588-1596. 10.1038/sj.bjc.6605946
-
(2010)
Br J Cancer
, vol.103
, Issue.10
, pp. 1588-1596
-
-
Daniel, R.1
Rozanska, A.2
Mulligan, E.3
Drew, Y.4
Thomas, H.5
Castelbuono, D.6
Hostomsky, Z.7
Plummer, E.8
Tweddle, D.9
Boddy, A.10
-
36
-
-
10744233628
-
Novel poly (ADP-ribose) polymerase-1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repair-deficient cells
-
Curtin NJ, Wang LZ, Yiakouvaki A, Kyle S, Arris CA, Canan-Koch S, Webber SE, Durkacz BW, Calvert HA, Hostomsky Z: Novel poly (ADP-ribose) polymerase-1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repair-deficient cells. Clin Cancer Res 2004, 10(3):881-889. 10.1158/1078-0432.CCR-1144-3
-
(2004)
Clin Cancer Res
, vol.10
, Issue.3
, pp. 881-889
-
-
Curtin, N.J.1
Wang, L.Z.2
Yiakouvaki, A.3
Kyle, S.4
Arris, C.A.5
Canan-Koch, S.6
Webber, S.E.7
Durkacz, B.W.8
Calvert, H.A.9
Hostomsky, Z.10
-
37
-
-
79959682172
-
Certain imidazotetrazines escape O6-methylguanine-DNA methyltransferase and mismatch repair
-
Zhang J, Stevens MF, Hummersone M, Madhusudan S, Laughton CA, Bradshaw TD: Certain imidazotetrazines escape O6-methylguanine-DNA methyltransferase and mismatch repair. Oncology 2011, 80(3-4):195-207.
-
(2011)
Oncology
, vol.80
, Issue.3-4
, pp. 195-207
-
-
Zhang, J.1
Stevens, M.F.2
Hummersone, M.3
Madhusudan, S.4
Laughton, C.A.5
Bradshaw, T.D.6
-
38
-
-
60849086456
-
Bcl-2 inhibitors: small molecules with a big impact on cancer therapy
-
Vogler M, Dinsdale D, Dyer MJS, Cohen GM: Bcl-2 inhibitors: small molecules with a big impact on cancer therapy. Cell Death & Differentiation 2008, 16(3):360-367.
-
(2008)
Cell Death & Differentiation
, vol.16
, Issue.3
, pp. 360-367
-
-
Vogler, M.1
Dinsdale, D.2
Dyer, M.J.S.3
Cohen, G.M.4
-
39
-
-
65849378710
-
Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics
-
Cragg MS, Harris C, Strasser A, Scott CL: Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics. Nat Rev Cancer 2009, 9(5):321-326. 10.1038/nrc2615
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.5
, pp. 321-326
-
-
Cragg, M.S.1
Harris, C.2
Strasser, A.3
Scott, C.L.4
-
40
-
-
42349098051
-
BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells
-
Huang S, Sinicrope FA: BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells. Cancer Res 2008, 68(8):2944-2951. 10.1158/0008-5472.CAN-07-2508
-
(2008)
Cancer Res
, vol.68
, Issue.8
, pp. 2944-2951
-
-
Huang, S.1
Sinicrope, F.A.2
-
41
-
-
7044246306
-
Bcl2 expression inversely correlates with tumour cell differentiation in medulloblastoma
-
Schüller U, Schober F, Kretzschmar H, Herms J: Bcl2 expression inversely correlates with tumour cell differentiation in medulloblastoma. Neuropathol Appl Neurobiol 2004, 30(5):513-521. 10.1111/j.1365-2990.2004.00553.x
-
(2004)
Neuropathol Appl Neurobiol
, vol.30
, Issue.5
, pp. 513-521
-
-
Schüller, U.1
Schober, F.2
Kretzschmar, H.3
Herms, J.4
-
42
-
-
0346840435
-
A 14; 18 and an 8; 14 chromosome translocation in a cell line derived from an acute B-cell leukemia
-
Pegoraro L, Palumbo A, Erikson J, Falda M, Giovanazzo B, Emanuel BS, Rovera G, Nowell PC, Croce CM: A 14; 18 and an 8; 14 chromosome translocation in a cell line derived from an acute B-cell leukemia. Proc Natl Acad Sci 1984, 81(22):7166-7170. 10.1073/pnas.81.22.7166
-
(1984)
Proc Natl Acad Sci
, vol.81
, Issue.22
, pp. 7166-7170
-
-
Pegoraro, L.1
Palumbo, A.2
Erikson, J.3
Falda, M.4
Giovanazzo, B.5
Emanuel, B.S.6
Rovera, G.7
Nowell, P.C.8
Croce, C.M.9
-
43
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
Oltersdorf T, Elmore SW, Shoemaker AR, Armstrong RC, Augeri DJ, Belli BA, Bruncko M, Deckwerth TL, Dinges J, Hajduk PJ: An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature 2005, 435(7042):677-681. 10.1038/nature03579
-
(2005)
Nature
, vol.435
, Issue.7042
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
Armstrong, R.C.4
Augeri, D.J.5
Belli, B.A.6
Bruncko, M.7
Deckwerth, T.L.8
Dinges, J.9
Hajduk, P.J.10
-
44
-
-
58149340656
-
A phase I study of the pan bcl-2 family inhibitor obatoclax mesylate in patients with advanced hematologic malignancies
-
Schimmer AD, O'Brien S, Kantarjian H, Brandwein J, Cheson BD, Minden MD, Yee K, Ravandi F, Giles F, Schuh A: A phase I study of the pan bcl-2 family inhibitor obatoclax mesylate in patients with advanced hematologic malignancies. Clin Cancer Res 2008, 14(24):8295-8301. 10.1158/1078-0432.CCR-08-0999
-
(2008)
Clin Cancer Res
, vol.14
, Issue.24
, pp. 8295-8301
-
-
Schimmer, A.D.1
O'Brien, S.2
Kantarjian, H.3
Brandwein, J.4
Cheson, B.D.5
Minden, M.D.6
Yee, K.7
Ravandi, F.8
Giles, F.9
Schuh, A.10
-
45
-
-
58849164097
-
Phase I study of obatoclax mesylate (GX15-070), a small molecule pan-Bcl-2 family antagonist, in patients with advanced chronic lymphocytic leukemia
-
O'Brien SM, Claxton DF, Crump M, Faderl S, Kipps T, Keating MJ, Viallet J, Cheson BD: Phase I study of obatoclax mesylate (GX15-070), a small molecule pan-Bcl-2 family antagonist, in patients with advanced chronic lymphocytic leukemia. Blood 2009, 113(2):299-305.
-
(2009)
Blood
, vol.113
, Issue.2
, pp. 299-305
-
-
O'Brien, S.M.1
Claxton, D.F.2
Crump, M.3
Faderl, S.4
Kipps, T.5
Keating, M.J.6
Viallet, J.7
Cheson, B.D.8
-
46
-
-
84856239462
-
RASSF1A and the BH3-only mimetic ABT-737 promote apoptosis in pediatric medulloblastoma cell lines
-
Levesley J, Lusher ME, Lindsey JC, Clifford SC, Grundy R, Coyle B: RASSF1A and the BH3-only mimetic ABT-737 promote apoptosis in pediatric medulloblastoma cell lines. Neuro Oncol 2011, 13(12):1265-1276. 10.1093/neuonc/nor129
-
(2011)
Neuro Oncol
, vol.13
, Issue.12
, pp. 1265-1276
-
-
Levesley, J.1
Lusher, M.E.2
Lindsey, J.C.3
Clifford, S.C.4
Grundy, R.5
Coyle, B.6
-
47
-
-
79955668070
-
The B-cell lymphoma 2 (BCL2)-inhibitors, ABT-737 and ABT-263, are substrates for P-glycoprotein
-
Vogler M, Dickens D, Dyer MJS, Owen A, Pirmohamed M, Cohen GM: The B-cell lymphoma 2 (BCL2)-inhibitors, ABT-737 and ABT-263, are substrates for P-glycoprotein. Biochem Biophys Res Commun 2011, 408(2):344-349. 10.1016/j.bbrc.2011.04.043
-
(2011)
Biochem Biophys Res Commun
, vol.408
, Issue.2
, pp. 344-349
-
-
Vogler, M.1
Dickens, D.2
Dyer, M.J.S.3
Owen, A.4
Pirmohamed, M.5
Cohen, G.M.6
-
48
-
-
84878857067
-
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma
-
Dubuc AM, Remke M, Korshunov A, Northcott PA, Zhan SH, Mendez-Lago M, Kool M, Jones DT, Unterberger A, Morrissy AS, Shih D, Peacock J, Ramaswamy V, Rolider A, Wang X, Witt H, Hielscher T, Hawkins C, Vibhakar R, Croul S, Rutka JT, Weiss WA, Jones SJ, Eberhart CG, Marra MA, Pfister SM, Taylor MD: Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma. Acta Neuropathol 2013, 125(3):373-384. doi:10.1007/s00401-012-1070-9 10.1007/s00401-012-1070-9
-
(2013)
Acta Neuropathol
, vol.125
, Issue.3
, pp. 373-384
-
-
Dubuc, A.M.1
Remke, M.2
Korshunov, A.3
Northcott, P.A.4
Zhan, S.H.5
Mendez-Lago, M.6
Kool, M.7
Jones, D.T.8
Unterberger, A.9
Morrissy, A.S.10
Shih, D.11
Peacock, J.12
Ramaswamy, V.13
Rolider, A.14
Wang, X.15
Witt, H.16
Hielscher, T.17
Hawkins, C.18
Vibhakar, R.19
Croul, S.20
Rutka, J.T.21
Weiss, W.A.22
Jones, S.J.23
Eberhart, C.G.24
Marra, M.A.25
Pfister, S.M.26
Taylor, M.D.27
more..
-
49
-
-
84863393028
-
Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas
-
Kool M, Korshunov A, Remke M, Jones DT, Schlanstein M, Northcott PA, Cho YJ, Koster J, Schouten Meeteren A, van Vuurden D, Clifford SC, Pietsch T, von Bueren AO, Rutkowski S, McCabe M, Collins VP, Backlund ML, Haberler C, Bourdeaut F, Delattre O, Doz F, Ellison DW, Gilbertson RJ, Pomeroy SL, Taylor MD, Lichter P, Pfister SM: Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas. Acta Neuropathol 2012, 123(4):473-484. doi:10.1007/s00401-012-0958-8 10.1007/s00401-012-0958-8
-
(2012)
Acta Neuropathol
, vol.123
, Issue.4
, pp. 473-484
-
-
Kool, M.1
Korshunov, A.2
Remke, M.3
Jones, D.T.4
Schlanstein, M.5
Northcott, P.A.6
Cho, Y.J.7
Koster, J.8
Schouten Meeteren, A.9
van Vuurden, D.10
Clifford, S.C.11
Pietsch, T.12
von Bueren, A.O.13
Rutkowski, S.14
McCabe, M.15
Collins, V.P.16
Backlund, M.L.17
Haberler, C.18
Bourdeaut, F.19
Delattre, O.20
Doz, F.21
Ellison, D.W.22
Gilbertson, R.J.23
Pomeroy, S.L.24
Taylor, M.D.25
Lichter, P.26
Pfister, S.M.27
more..
-
50
-
-
79953321410
-
Rapid diagnosis of medulloblastoma molecular subgroups
-
Schwalbe EC, Lindsey JC, Straughton D, Hogg TL, Cole M, Megahed H, Ryan SL, Lusher ME, Taylor MD, Gilbertson RJ: Rapid diagnosis of medulloblastoma molecular subgroups. Clin Cancer Res 2011, 17(7):1883-1894. 10.1158/1078-0432.CCR-10-2210
-
(2011)
Clin Cancer Res
, vol.17
, Issue.7
, pp. 1883-1894
-
-
Schwalbe, E.C.1
Lindsey, J.C.2
Straughton, D.3
Hogg, T.L.4
Cole, M.5
Megahed, H.6
Ryan, S.L.7
Lusher, M.E.8
Taylor, M.D.9
Gilbertson, R.J.10
-
51
-
-
79954444747
-
Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups
-
Ellison DW, Dalton J, Kocak M, Nicholson SL, Fraga C, Neale G, Kenney AM, Brat DJ, Perry A, Yong WH: Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups. Acta Neuropathol 2011, 121(3):381-396. 10.1007/s00401-011-0800-8
-
(2011)
Acta Neuropathol
, vol.121
, Issue.3
, pp. 381-396
-
-
Ellison, D.W.1
Dalton, J.2
Kocak, M.3
Nicholson, S.L.4
Fraga, C.5
Neale, G.6
Kenney, A.M.7
Brat, D.J.8
Perry, A.9
Yong, W.H.10
-
52
-
-
0029553905
-
Establishment and characterization of four human medulloblastoma-derived cell lines
-
Keles GE, Berger MS, Srinivasan J, Kolstoe DD, Bobola MS, Silber JR: Establishment and characterization of four human medulloblastoma-derived cell lines. Oncol Res 1995, 7(10-11):493.
-
(1995)
Oncol Res
, vol.7
, Issue.10-11
, pp. 493
-
-
Keles, G.E.1
Berger, M.S.2
Srinivasan, J.3
Kolstoe, D.D.4
Bobola, M.S.5
Silber, J.R.6
-
53
-
-
56149086808
-
Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma
-
Ridley L, Rahman R, Brundler MA, Ellison D, Lowe J, Robson K, Prebble E, Luckett I, Gilbertson RJ, Parkes S: Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma. Neuro Oncol 2008, 10(5):675-689. 10.1215/15228517-2008-036
-
(2008)
Neuro Oncol
, vol.10
, Issue.5
, pp. 675-689
-
-
Ridley, L.1
Rahman, R.2
Brundler, M.A.3
Ellison, D.4
Lowe, J.5
Robson, K.6
Prebble, E.7
Luckett, I.8
Gilbertson, R.J.9
Parkes, S.10
-
54
-
-
84871556659
-
Expression of Wnt 3a, β-Catenin, Cyclin D1 and PCNA in Mouse Dentate Gyrus Subgranular Zone (SGZ): a Possible Role of Wnt Pathway in SGZ Neural Stem Cell Proliferation
-
Kumar D, Devaraj H: Expression of Wnt 3a, β-Catenin, Cyclin D1 and PCNA in Mouse Dentate Gyrus Subgranular Zone (SGZ): a Possible Role of Wnt Pathway in SGZ Neural Stem Cell Proliferation. Folia Biol (Praha) 2012, 58: 115-120.
-
(2012)
Folia Biol (Praha)
, vol.58
, pp. 115-120
-
-
Kumar, D.1
Devaraj, H.2
-
55
-
-
84860378325
-
Global gene expression profiling confirms the molecular fidelity of primary tumor-based orthotopic xenograft mouse models of medulloblastoma
-
Zhao X, Liu Z, Yu L, Zhang Y, Baxter P, Voicu H, Gurusiddappa S, Luan J, Su JM, Leung H-cE: Global gene expression profiling confirms the molecular fidelity of primary tumor-based orthotopic xenograft mouse models of medulloblastoma. Neuro Oncol 2012, 14(5):574-583. 10.1093/neuonc/nos061
-
(2012)
Neuro Oncol
, vol.14
, Issue.5
, pp. 574-583
-
-
Zhao, X.1
Liu, Z.2
Yu, L.3
Zhang, Y.4
Baxter, P.5
Voicu, H.6
Gurusiddappa, S.7
Luan, J.8
Su, J.M.9
Leung, H.-C.10
-
56
-
-
9144266455
-
Multiple drug resistance protein (MDR-1), multidrug resistance-related protein (MRP) and lung resistance protein (LRP) gene expression in childhood acute lymphoblastic leukemia
-
Valera ET, Scrideli CA, Queiroz R, Mori B, Tone LG: Multiple drug resistance protein (MDR-1), multidrug resistance-related protein (MRP) and lung resistance protein (LRP) gene expression in childhood acute lymphoblastic leukemia. Sao Paulo Med J 2004, 122(4):166-171. 10.1590/S1516-31802004000400007
-
(2004)
Sao Paulo Med J
, vol.122
, Issue.4
, pp. 166-171
-
-
Valera, E.T.1
Scrideli, C.A.2
Queiroz, R.3
Mori, B.4
Tone, L.G.5
-
57
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
PfafflMW: A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001, 29(9):e45-e45. 10.1093/nar/29.9.e45
-
(2001)
Nucleic Acids Res
, vol.29
, Issue.9
, pp. 45
-
-
Pfaffl, M.W.1
-
58
-
-
79951825581
-
Homozygous loss of ADAM3A revealed by genome-wide analysis of pediatric high-grade glioma and diffuse intrinsic pontine gliomas
-
Barrow J, Adamowicz-Brice M, Cartmill M, MacArthur D, Lowe J, Robson K, Brundler M-A, Walker DA, Coyle B, Grundy R: Homozygous loss of ADAM3A revealed by genome-wide analysis of pediatric high-grade glioma and diffuse intrinsic pontine gliomas. Neuro Oncol 2011, 13(2):212-222. 10.1093/neuonc/noq158
-
(2011)
Neuro Oncol
, vol.13
, Issue.2
, pp. 212-222
-
-
Barrow, J.1
Adamowicz-Brice, M.2
Cartmill, M.3
MacArthur, D.4
Lowe, J.5
Robson, K.6
Brundler, M.-A.7
Walker, D.A.8
Coyle, B.9
Grundy, R.10
-
59
-
-
84862685324
-
MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma
-
Ryan SL, Schwalbe EC, Cole M, Lu Y, Lusher ME, Megahed H, O'Toole K, Nicholson SL, Bognar L, Garami M, Hauser P, Korshunov A, Pfister SM, Williamson D, Taylor RE, Ellison DW, Bailey S, Clifford SC: MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma. Acta Neuropathol 2012, 123(4):501-513. doi:10.1007/s00401-011-0923-y 10.1007/s00401-011-0923-y
-
(2012)
Acta Neuropathol
, vol.123
, Issue.4
, pp. 501-513
-
-
Ryan, S.L.1
Schwalbe, E.C.2
Cole, M.3
Lu, Y.4
Lusher, M.E.5
Megahed, H.6
O'Toole, K.7
Nicholson, S.L.8
Bognar, L.9
Garami, M.10
Hauser, P.11
Korshunov, A.12
Pfister, S.M.13
Williamson, D.14
Taylor, R.E.15
Ellison, D.W.16
Bailey, S.17
Clifford, S.C.18
-
60
-
-
79955034739
-
Medulloblastoma comprises four distinct molecular variants
-
Northcott PA, Korshunov A, Witt H, Hielscher T, Eberhart CG, Mack S, Bouffet E, Clifford SC, Hawkins CE, French P: Medulloblastoma comprises four distinct molecular variants. J Clin Oncol 2011, 29(11):1408-1414. 10.1200/JCO.2009.27.4324
-
(2011)
J Clin Oncol
, vol.29
, Issue.11
, pp. 1408-1414
-
-
Northcott, P.A.1
Korshunov, A.2
Witt, H.3
Hielscher, T.4
Eberhart, C.G.5
Mack, S.6
Bouffet, E.7
Clifford, S.C.8
Hawkins, C.E.9
French, P.10
-
61
-
-
80053980912
-
FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma
-
Remke M, Hielscher T, Korshunov A, Northcott PA, Bender S, Kool M, Westermann F, Benner A, Cin H, Ryzhova M: FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma. J Clin Oncol 2011, 29(29):3852-3861. 10.1200/JCO.2011.36.2798
-
(2011)
J Clin Oncol
, vol.29
, Issue.29
, pp. 3852-3861
-
-
Remke, M.1
Hielscher, T.2
Korshunov, A.3
Northcott, P.A.4
Bender, S.5
Kool, M.6
Westermann, F.7
Benner, A.8
Cin, H.9
Ryzhova, M.10
-
62
-
-
84891722793
-
Overcoming resistance to sonic hedgehog inhibition by targeting p90 ribosomal S6 kinase in pediatric medulloblastoma
-
Pambid MR, Berns R, Adomat HH, Hu K, Triscott J, Maurer N, Zisman N, Ramaswamy V, Hawkins CE, Taylor MD: Overcoming resistance to sonic hedgehog inhibition by targeting p90 ribosomal S6 kinase in pediatric medulloblastoma. Pediatr Blood Cancer 2014, 61(1):107-115. 10.1002/pbc.24675
-
(2014)
Pediatr Blood Cancer
, vol.61
, Issue.1
, pp. 107-115
-
-
Pambid, M.R.1
Berns, R.2
Adomat, H.H.3
Hu, K.4
Triscott, J.5
Maurer, N.6
Zisman, N.7
Ramaswamy, V.8
Hawkins, C.E.9
Taylor, M.D.10
-
63
-
-
79952993517
-
Multidrug efflux pumps and cancer stem cells: insights into multidrug resistance and therapeutic development
-
Moitra K, Lou H, Dean M: Multidrug efflux pumps and cancer stem cells: insights into multidrug resistance and therapeutic development. Basic Clin Pharmacol Toxicol 2011, 89(4):491-502.
-
(2011)
Basic Clin Pharmacol Toxicol
, vol.89
, Issue.4
, pp. 491-502
-
-
Moitra, K.1
Lou, H.2
Dean, M.3
-
64
-
-
0018595465
-
Therapeutic trials with VP-16-213 and VM-26: active agents in small cell lung cancer, non-Hodgkin's lymphomas, and other malignancies
-
Radice P, Bunn P Jr, Ihde D: Therapeutic trials with VP-16-213 and VM-26: active agents in small cell lung cancer, non-Hodgkin's lymphomas, and other malignancies. Cancer Treat Rep 1979, 63(8):1231-1239.
-
(1979)
Cancer Treat Rep
, vol.63
, Issue.8
, pp. 1231-1239
-
-
Radice, P.1
Bunn, P.2
Ihde, D.3
-
65
-
-
0023237840
-
Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patients
-
Ozols RF, Cunnion RE, Klecker RW Jr, Hamilton TC, Ostchega Y, Parrillo JE, Young RC: Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patients. J Clin Oncol 1987, 5(4):641-647.
-
(1987)
J Clin Oncol
, vol.5
, Issue.4
, pp. 641-647
-
-
Ozols, R.F.1
Cunnion, R.E.2
Klecker, R.W.3
Hamilton, T.C.4
Ostchega, Y.5
Parrillo, J.E.6
Young, R.C.7
-
66
-
-
33644912648
-
Effect of vardenafil, an inhibitor of phosphodiesterase5, on portal haemodynamics in normal and cirrhotic liver-results of a pilot study
-
Deibert P, SCHUMACHER YO, Ruecker G, Opitz O, Blum H, Rössle M, Kreisel W: Effect of vardenafil, an inhibitor of phosphodiesterase5, on portal haemodynamics in normal and cirrhotic liver-results of a pilot study. Aliment Pharmacol Ther 2006, 23(1):121-128. 10.1111/j.1365-2036.2006.02735.x
-
(2006)
Aliment Pharmacol Ther
, vol.23
, Issue.1
, pp. 121-128
-
-
Deibert, P.1
SCHUMACHER, Y.O.2
Ruecker, G.3
Opitz, O.4
Blum, H.5
Rössle, M.6
Kreisel, W.7
-
67
-
-
84894630218
-
Paediatric pulmonary hypertension and sildenafil: current practice and controversies
-
Wardle AJ, Tulloh RM: Paediatric pulmonary hypertension and sildenafil: current practice and controversies. Arch Dis Child Educ Pract Ed 2013, 98(4):141-147. doi:10.1136/archdischild-2013-303981 10.1136/archdischild-2013-303981
-
(2013)
Arch Dis Child Educ Pract Ed
, vol.98
, Issue.4
, pp. 141-147
-
-
Wardle, A.J.1
Tulloh, R.M.2
-
68
-
-
77956326618
-
Phosphodiesterase type 5 inhibitors increase Herceptin transport and treatment efficacy in mouse metastatic brain tumor models
-
Hu J, Ljubimova JY, Inoue S, Konda B, Patil R, Ding H, Espinoza A, Wawrowsky KA, Patil C, Ljubimov AV: Phosphodiesterase type 5 inhibitors increase Herceptin transport and treatment efficacy in mouse metastatic brain tumor models. PLoS One 2010, 5(4):e10108. 10.1371/journal.pone.0010108
-
(2010)
PLoS One
, vol.5
, Issue.4
-
-
Hu, J.1
Ljubimova, J.Y.2
Inoue, S.3
Konda, B.4
Patil, R.5
Ding, H.6
Espinoza, A.7
Wawrowsky, K.A.8
Patil, C.9
Ljubimov, A.V.10
-
69
-
-
79955726360
-
The phosphodiesterase-5 inhibitor vardenafil is a potent inhibitor of ABCB1/P-glycoprotein transporter
-
Ding PR, Tiwari AK, Ohnuma S, Lee JWKK, An X, Dai CL, Lu QS, Singh S, Yang DH, Talele TT: The phosphodiesterase-5 inhibitor vardenafil is a potent inhibitor of ABCB1/P-glycoprotein transporter. PLoS One 2011, 6(4):e19329. 10.1371/journal.pone.0019329
-
(2011)
PLoS One
, vol.6
, Issue.4
-
-
Ding, P.R.1
Tiwari, A.K.2
Ohnuma, S.3
Lee, J.W.K.K.4
An, X.5
Dai, C.L.6
Lu, Q.S.7
Singh, S.8
Yang, D.H.9
Talele, T.T.10
-
70
-
-
79952291173
-
Phase I study of Navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors
-
Gandhi L, Camidge DR, de Oliveira MR, Bonomi P, Gandara D, Khaira D, Hann CL, McKeegan EM, Litvinovich E, Hemken PM: Phase I study of Navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors. J Clin Oncol 2011, 29(7):909-916. 10.1200/JCO.2010.31.6208
-
(2011)
J Clin Oncol
, vol.29
, Issue.7
, pp. 909-916
-
-
Gandhi, L.1
Camidge, D.R.2
de Oliveira, M.R.3
Bonomi, P.4
Gandara, D.5
Khaira, D.6
Hann, C.L.7
McKeegan, E.M.8
Litvinovich, E.9
Hemken, P.M.10
-
71
-
-
33847061737
-
Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737
-
Tahir SK, Yang X, Anderson MG, Morgan-Lappe SE, Sarthy AV, Chen J, Warner RB, Ng SC, Fesik SW, Elmore SW: Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737. Cancer Res 2007, 67(3):1176-1183. 10.1158/0008-5472.CAN-06-2203
-
(2007)
Cancer Res
, vol.67
, Issue.3
, pp. 1176-1183
-
-
Tahir, S.K.1
Yang, X.2
Anderson, M.G.3
Morgan-Lappe, S.E.4
Sarthy, A.V.5
Chen, J.6
Warner, R.B.7
Ng, S.C.8
Fesik, S.W.9
Elmore, S.W.10
-
72
-
-
33646354381
-
Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
-
Certo M, Del Gaizo MV, Nishino M, Wei G, Korsmeyer S, Armstrong SA, Letai A: Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members. Cancer Cell 2006, 9(5):351-365. 10.1016/j.ccr.2006.03.027
-
(2006)
Cancer Cell
, vol.9
, Issue.5
, pp. 351-365
-
-
Certo, M.1
Del Gaizo, M.V.2
Nishino, M.3
Wei, G.4
Korsmeyer, S.5
Armstrong, S.A.6
Letai, A.7
-
73
-
-
42049104916
-
Therapeutic efficacy of ABT-737, a selective inhibitor of BCL-2, in small cell lung cancer
-
Hann CL, Daniel VC, Sugar EA, Dobromilskaya I, Murphy SC, Cope L, Lin X, Hierman JS, Wilburn DL, Watkins DN: Therapeutic efficacy of ABT-737, a selective inhibitor of BCL-2, in small cell lung cancer. Cancer Res 2008, 68(7):2321-2328. 10.1158/0008-5472.CAN-07-5031
-
(2008)
Cancer Res
, vol.68
, Issue.7
, pp. 2321-2328
-
-
Hann, C.L.1
Daniel, V.C.2
Sugar, E.A.3
Dobromilskaya, I.4
Murphy, S.C.5
Cope, L.6
Lin, X.7
Hierman, J.S.8
Wilburn, D.L.9
Watkins, D.N.10
-
74
-
-
77951442337
-
Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1
-
Yecies D, Carlson NE, Deng J, Letai A: Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1. Blood 2010, 115(16):3304-3313. 10.1182/blood-2009-07-233304
-
(2010)
Blood
, vol.115
, Issue.16
, pp. 3304-3313
-
-
Yecies, D.1
Carlson, N.E.2
Deng, J.3
Letai, A.4
-
75
-
-
66149147044
-
Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia
-
Vogler M, Butterworth M, Majid A, Walewska RJ, Sun XM, Dyer MJS, Cohen GM: Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia. Blood 2009, 113(18):4403-4413. 10.1182/blood-2008-08-173310
-
(2009)
Blood
, vol.113
, Issue.18
, pp. 4403-4413
-
-
Vogler, M.1
Butterworth, M.2
Majid, A.3
Walewska, R.J.4
Sun, X.M.5
Dyer, M.J.S.6
Cohen, G.M.7
-
76
-
-
77956257700
-
Actinomycin D decreases Mcl-1 expression and acts synergistically with ABT-737 against small cell lung cancer cell lines
-
Xu H, Krystal GW: Actinomycin D decreases Mcl-1 expression and acts synergistically with ABT-737 against small cell lung cancer cell lines. Clin Cancer Res 2010, 16(17):4392-4400. 10.1158/1078-0432.CCR-10-0640
-
(2010)
Clin Cancer Res
, vol.16
, Issue.17
, pp. 4392-4400
-
-
Xu, H.1
Krystal, G.W.2
-
77
-
-
33750628289
-
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia
-
Konopleva M, Contractor R, Tsao T, Samudio I, Ruvolo PP, Kitada S, Deng X, Zhai D, Shi Y-X, Sneed T: Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia. Cancer Cell 2006, 10(5):375-388. 10.1016/j.ccr.2006.10.006
-
(2006)
Cancer Cell
, vol.10
, Issue.5
, pp. 375-388
-
-
Konopleva, M.1
Contractor, R.2
Tsao, T.3
Samudio, I.4
Ruvolo, P.P.5
Kitada, S.6
Deng, X.7
Zhai, D.8
Shi, Y.-X.9
Sneed, T.10
-
78
-
-
33750834023
-
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
-
van Delft MF, Wei AH, Mason KD, Vandenberg CJ, Chen L, Czabotar PE, Willis SN, Scott CL, Day CL, Cory S: The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. Cancer Cell 2006, 10(5):389-399. 10.1016/j.ccr.2006.08.027
-
(2006)
Cancer Cell
, vol.10
, Issue.5
, pp. 389-399
-
-
van Delft, M.F.1
Wei, A.H.2
Mason, K.D.3
Vandenberg, C.J.4
Chen, L.5
Czabotar, P.E.6
Willis, S.N.7
Scott, C.L.8
Day, C.L.9
Cory, S.10
-
79
-
-
0032812622
-
Phase I and pharmacokinetic study of temozolomide on a daily-for-5-days schedule in patients with advanced solid malignancies
-
Hammond LA, Eckardt JR, Baker SD, Eckhardt SG, Dugan M, Forral K, Reidenberg P, Statkevich P, Weiss GR, Rinaldi DA: Phase I and pharmacokinetic study of temozolomide on a daily-for-5-days schedule in patients with advanced solid malignancies. J Clin Oncol 1999, 17(8):2604-2604.
-
(1999)
J Clin Oncol
, vol.17
, Issue.8
, pp. 2604-2604
-
-
Hammond, L.A.1
Eckardt, J.R.2
Baker, S.D.3
Eckhardt, S.G.4
Dugan, M.5
Forral, K.6
Reidenberg, P.7
Statkevich, P.8
Weiss, G.R.9
Rinaldi, D.A.10
|