Renoprotective effects of the direct renin inhibitor aliskiren on gentamicin-induced nephrotoxicity in rats

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 15, Issue 4, 2014, Pages 348-361

  Bae, Eun Hui ^a   Kim, In Jin ^a   Joo, Soo Yeon ^a   Kim, Eun Young ^a   Choi, Joon Seok ^a   Kim, Chang Seong ^a   Ma, Seong Kwon ^a   Lee, Jongun ^a   Kim, Soo Wan ^a  

^a Chonnam National University Medical School   (South Korea)

Author keywords

Aliskiren; apoptosis; fibrosis; gentamicin; inflammation

Indexed keywords

ALISKIREN; GAMMA INTERFERON; GENTAMICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; AMIDE; ATP6AP2 PROTEIN, RAT; AUTACOID; CELL ADHESION MOLECULE; CELL SURFACE RECEPTOR; CYTOKINE; FUMARIC ACID DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; PROTECTIVE AGENT; PROTEIN BAX; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; RENIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CREATININE CLEARANCE; GENTAMICIN INDUCED NEPHROTOXICITY; GLOMERULOSCLEROSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY FIBROSIS; KIDNEY TUBULE EPITHELIUM; MALE; NEPHROTOXICITY; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; RAT; RENAL PROTECTION; SODIUM EXCRETION; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; DRUG EFFECTS; ENZYMOLOGY; FIBROSIS; GENETICS; IMMUNOBLOTTING; KIDNEY; KIDNEY DISEASES; KIDNEY FUNCTION TEST; KIDNEY TUBULE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

AMIDES; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL ADHESION MOLECULES; CYTOKINES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROSIS; FUMARATES; GENTAMICINS; HUMANS; IMMUNOBLOTTING; INFLAMMATION MEDIATORS; KIDNEY; KIDNEY DISEASES; KIDNEY FUNCTION TESTS; KIDNEY TUBULES; MALE; NF-KAPPA B; PROTECTIVE AGENTS; PROTON-TRANSLOCATING ATPASES; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CELL SURFACE; RENIN; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84918586757     PISSN: 14703203     EISSN: 17528976     Source Type: Journal    
DOI: 10.1177/1470320312474853     Document Type: Article

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