Persistent associations between maternal prenatal exposure to phthalates on child IQ at age 7 years

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Factor Litvak, Pam ^a   Insel, Beverly ^a   Calafat, Antonia M ^b   Liu, Xinhua ^a   Perera, Frederica ^a   Rauh, Virginia A ^a   Whyatt, Robin M ^a  

^a Department of Medicine   (United States)

^b NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHTHALIC ACID BENZYL BUTYL ESTER; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PHTHALIC ACID DERIVATIVE; PHTHALIC ACID DI ISOBUTYL ESTER; PHTHALIC ACID DIBUTYL ESTER; PHTHALIC ACID DIETHYL ESTER; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CHILD; COGNITION; COMPREHENSION; CONTROLLED STUDY; FEMALE; HUMAN; INTELLIGENCE QUOTIENT; MALE; MENTAL DEVELOPMENT; PERCEPTION; PRENATAL EXPOSURE; PROCESSING SPEED; SCHOOL CHILD; SHORT TERM MEMORY; URINE LEVEL; WORKING MEMORY; ADOLESCENT; DRUG EFFECTS; ENVIRONMENTAL EXPOSURE; INTELLIGENCE; LONGITUDINAL STUDY; PREGNANCY; THIRD TRIMESTER PREGNANCY; URINE; YOUNG ADULT;

ADOLESCENT; ADULT; CHILD; ENVIRONMENTAL EXPOSURE; FEMALE; HUMANS; INTELLIGENCE; LONGITUDINAL STUDIES; MALE; PHTHALIC ACIDS; PREGNANCY; PREGNANCY TRIMESTER, THIRD; PRENATAL EXPOSURE DELAYED EFFECTS; YOUNG ADULT;

EID: 84918586055     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0114003     Document Type: Article

References (32)

1. Sathyanarayana S (2008) Phthalates and children's health. Curr Probl Pediatr Adolesc Health Care 38: 34-49.
2. Braun JM, Sathyanarayana S, Hauser R (2013) Phthalate exposure and children's health. Current opinion in pediatrics 25: 247-54.
3. Bellinger DC (2013). Prenatal Exposures to Environmental Chemicals and Children's Neurodevelopment: An Update. Saf Health Work 4: 1-11.
4. CDC. Fourth National Report on Human Exposure to Environmental Chemicals. Centers for Disease Control and Prevention Department of Health and Human Services. Available: http://wwwcdcgov/ exposurereport Accessed 2011 February 25.
5. Whyatt RM, Liu X, Rauh VA, Calafat AM, Just AC, et al. (2012) Maternal prenatal urinary phthalate metabolite concentrations and child mental, psychomotor, and behavioral development at 3 years of age. Environ Health Perspect 120: 290-5.
6. Kato K, Silva MJ, Reidy JA, Hurtz D 3rd, Malek NA, et al. (2004) Mono(2-ethyl-5-hydroxyhexyl) phthalate and mono-(2-ethyl-5-oxohexyl) phthalate as biomarkers for human exposure assessment to di-(2-ethylhexyl) phthalate. Environ Health Perspect 112: 327-30.
7. Hauser R, Meeker JD, Park S, Silva MJ, Calafat AM (2004) Temporal variability of urinary phthalate metabolite levels in men of reproductive age. Environ Health Perspect 112: 1734-40.
8. Teitelbaum SL, Britton JA, Calafat AM, Ye X, Silva MJ, et al. (2008) Temporal variability in urinary concentrations of phthalate metabolites, phytoestrogens and phenols among minority children in the United States. Environ Res 106: 257-69.
9. Adibi JJ, Whyatt RM, Williams PL, Calafat AM, Camann D, et al. (2008) Characterization of Phthalate Exposure among Pregnant Women Assessed by Repeat Air and Urine Samples. Environ Health Perspect 116: 467-73.
10. Kim Y, Ha EH, Kim EJ, Park H, Ha M, et al. (2011) Prenatal exposure to phthalates and infant development at 6 months: prospective Mothers and Children's Environmental Health (MOCEH) study. Environ Health Perspect 119: 1495-500.
11. Li Y, Zhuang M, Li T, Shi N (2009) Neurobehavioral toxicity study of dibutyl phthalate on rats following in utero and lactational exposure. J Appl Toxicol 29: 603-11.
12. Boberg J, Christiansen S, Axelstad M, Kledal TS, Vinggaard AM, et al. (2011) Reproductive and behavioral effects of diisononyl phthalate (DINP) in perinatally exposed rats. Reprod Toxicol 31: 200-9.
13. Cho SC1, Bhang SY, Hong YC, Shin MS, Kim BN, et al. (2010) Relationship between environmental phthalate exposure and the intelligence of school-age children. Environ Health Perspect 118: 1027-32.
14. Perera FP, Rauh V, Tsai WY, Kinney P, Camann D, et al. (2003) Effects of transplacental exposure to environmental pollutants on birth outcomes in a multiethnic population. Environ Health Perspect 111: 201-5.
15. Silva MJ, Barr DB, Reidy JA, Malek NA, Hodge CC, et al. (2004) Urinary levels of seven phthalate metabolites in the U.S. population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000. Environ Health Perspect; 112: 331-8.
16. Wechsler D (2003) Wechsler Intelligence Scale for Children, 4th edition. San Antonio, TX: Psychological Corporation.
17. Rauh V, Arunajadai S, Horton M, Perera F, Hoepner L, et al. (2011) Seven-year neurodevelopmental scores and prenatal exposure to chlorpyrifos, a common agricultural pesticide. Environ Health Perspect 119: 1196-201.
18. Bouchard MF, Chevrier J, Harley KG, Kogut K, Vedar M, et al. (2011) Prenatal exposure to organophosphate pesticides and IQ in 7-year-old children. Environ Health Perspect 119: 1189-95.
19. Jusko TA, Henderson CR, Lanphear BP, Cory-Slechta DA, Parsons PJ, et al. (2008) Blood lead concentrations ,10 microg/dL and child intelligence at 6 years of age. Environ Health Perspect 116: 243-8.
20. Dohrenwend BS, Krasnoff L, Askenasy AR, Dohrenwend BP (1978) Exemplification of a method for scaling life events: the Peri Life Events Scale. J Health Soc Behav 19: 205-29.
21. Brown L, Sherbenou RJ, Johnson SK (1990) Test of Non-verbal Intelligence: A language-Free Measure of Cognitive Ability. Austin, TX: PRO-ED.
22. Caldwell BM, Bradley RH (1979) Home observation for measurement of the environment. Little Rock: University of Arkansas Press.
23. Hornung RW, Reed DL (1990) Estimation of average concentration in the presence of nondetectable values. Appl Occup Environ Hyg 5: 46-51.
24. Engel SM, Zhu C, Berkowitz GS, Calafat AM, Silva MJ, et al. (2009) Prenatal phthalate exposure and performance on the Neonatal Behavioral Assessment Scale in a multiethnic birth cohort. Neurotoxicology 30: 522-8.
25. Yolton K, Xu Y, Strauss D, Altaye M, Calafat AM, et al. (2011) Prenatal exposure to bisphenol A and phthalates and infant neurobehavior. Neurotoxicol Teratol 33: 558-66.
26. Téllez-Rojo MM, Cantoral A, Cantonwine DE, Schnaas L, Peterson K, et al. (2013) Prenatal urinary phthalate metabolites levels and neurodevelopment in children at two and three years of age. Sci Total Environ 461-462: 386-90.
27. Zota AR, Calafat AM, Woodruff TJ (2014) Temporal trends in phthalate exposures: Findings from the National Health and Nutrition Examination Survey, 2001-2010. Environ Health Perspect 122: 235-41.
28. Weiss B (2012) The intersection of neurotoxicology and endocrine disruption. Neurotoxicology 33: 1410-1419.
29. Wolstenholme JT, Rissman EF, Connelly JJ (2011) The role of Bisphenol A in shaping the brain, epigenome and behavior. Horm Behav 59: 296-305.
30. Howdeshell KL, Wilson VS, Furr J, Lambright CR, Rider CV, et al. (2008) A mixture of five phthalate esters inhibits fetal testicular testosterone production in the Sprague Dawley rat in a cummulative, dose additive manner. Toxicological Sciences 105: 153-165.
31. Andrade AJ, Grande SW, Talsness CE, Grote K, Chahoud I (2006) A dose-response study following in utero and lactational exposure to di-(2-ethylhexyl)-phthalate (DEHP): non-monotonic dose-response and low dose effects on rat brain aromatase activity. Toxicology 227: 185-192.
32. Bonefeld-Jorgensen EC, Long M, Hofmeister MV, Vinggaard AM (2007) Endocrine-disrupting potential of bisphenol A, bisphenol A dimethacrylate, 4-n-nonylphenol, and 4-n-octylphenol in vitro: new data and a brief review. Environ Health Perspect 115 Suppl 1:: 69-76.