Serotonin/dopamine interactions in a hyperactive mouse: Reduced serotonin receptor 1B activity reverses effects of dopamine transporter knockout

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Hall, Frank Scott ^a,b   Sora, Ichiro ^c   Hen, René ^d,e   Uhl, George R ^b  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^c KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d Departments of Pharmacology Neuroscience and Pharmacology Columbia University ^*  (United States)

^e NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,6,7 TETRAHYDRO 1' METHYL 5 [[2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL) 4 BIPHENYLYL]CARBONYL]SPIRO[FURO[2,3 F]INDOLE 3,4' PIPERIDINE]; COCAINE; DOPAMINE TRANSPORTER; SEROTONIN 1B ANTAGONIST; SEROTONIN 1B RECEPTOR; DOPAMINE; DOPAMINE UPTAKE INHIBITOR; PIPERIDONE DERIVATIVE; SB 22489G; SEROTONIN; SEROTONIN 1 ANTAGONIST; SPIRO COMPOUND;

ANIMAL EXPERIMENT; ARTICLE; ATTENTION DEFICIT DISORDER; CONTROLLED STUDY; FEMALE; GENETIC COMPLEMENTATION; GENETIC VARIABILITY; HETEROZYGOSITY; HYPERACTIVITY; KNOCKOUT MOUSE; LOCOMOTION; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; ANIMAL; C57BL MOUSE; DRUG EFFECTS; GENETICS; METABOLISM; MOTOR ACTIVITY;

MUS;

ANIMALS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; COCAINE; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; LOCOMOTION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; PIPERIDONES; RECEPTOR, SEROTONIN, 5-HT1B; SEROTONIN; SEROTONIN 5-HT1 RECEPTOR ANTAGONISTS; SPIRO COMPOUNDS;

EID: 84918578872     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0115009     Document Type: Article

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