Biphasic alterations in Serotonin-1B (5-HT1B) receptor function during abstinence from extended cocaine self-administration

Journal of Neurochemistry

Volumn 99, Issue 5, 2006, Pages 1363-1376

  O'Dell, Laura E ^b   Manzardo, Ann M ^c   Polis, Ilham ^a   Stouffer, David G ^a   Parsons, Loren H ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF TEXAS AT EL PASO   (United States)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Cocaine; Dopamine; Microdialysis; Self administration; Serotonin1B; Withdrawal

Indexed keywords

3 (1,2,5,6 TETRAHYDRO 4 PYRIDYL)PYRROLO[3,2 B]PYRIDIN 5 ONE; 5 METHOXY 3 (1,2,3,6 TETRAHYDRO 4 PYRIDYL) 1H INDOLE; COCAINE; DOPAMINE; SEROTONIN 1A AGONIST; SEROTONIN 1B AGONIST; SEROTONIN 1B RECEPTOR;

ABSTINENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIALYSATE; DRUG SELF ADMINISTRATION; LOCOMOTION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; RAT STRAIN; STATISTICAL SIGNIFICANCE;

ANIMALS; BRAIN; COCAINE; COCAINE-RELATED DISORDERS; DISEASE MODELS, ANIMAL; DOPAMINE; DOPAMINE UPTAKE INHIBITORS; MALE; MOTOR ACTIVITY; NEURAL PATHWAYS; NUCLEUS ACCUMBENS; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT1B; REWARD; SELF ADMINISTRATION; SEROTONIN; SEROTONIN AGONISTS; SUBSTANCE WITHDRAWAL SYNDROME; SYNAPTIC TRANSMISSION; VENTRAL TEGMENTAL AREA;

ANIMALIA;

EID: 33750921283     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04163.x     Document Type: Article

References (110)

1. 1B receptors decreases cocaine- and sucrose-seeking behavior. Pharmacol. Biochem. Behav. 80, 297-307.
2. B autoreceptors in median eminance. Eur. J. Pharmacol. 188, 355-358.
3. Aronson S. C., Black J. E., McDougle C. J., Scanley B. E., Jatlow P., Kosten T. R., Heninger G. R. and Price L. H. (1995) Serotonergic mechanisms of cocaine effects in humans. Psychopharmacol. 119, 179-185.
4. Bell K., Duffy P. and Kalivas P. W. (2000) Context-specific enhancement of glutamte transmission by cocaine. Neuropsychopharmacology 23, 335-344.
5. 1B characterizing agents in the mouse elevated plus maze. Life Sci. 47, 195-203.
6. Benloucif S., Keegan M. J. and Galloway M. P. (1993) Serotonin- facilitated dopamine release in vivo: pharmacological characterization. J. Pharmacol. Exp. Ther. 265, 373-377.
7. 1B/1D receptor endogenous modulator, interacts with dopamine release measured in vivo by microdialysis. Eur. J. Pharmacol. 358, 129-137.
8. 1B receptor are negatively coupled with adenylate cyclase in rat substantia nigra. Eur. J. Pharmacol. 151, 189-196.
9. 1B receptors in the rat. Hippocampus 5, 198-208.
10. Buydens-Branchey L., Branchey M., Fergeson P., Hudson J. and McKerin C. (1997) Craving for cocaine in addicted users. Role of serotonergic mechanisms. Am. J. Addict. 6, 65-73.
11. 2C receptors. J. Pharmacol. Exp. Ther. 274, 1414-1424.
12. 1B receptor agonists. Neuropharmacology 36, 373-381.
13. Callaway C. W. and Geyer M. A. (1992) Tolerance and cross-tolerance to the activating effects of 3,4-methylenedioxymethamphetamine and a 5-hydroxytryptamine1B agonist. J. Pharmacol. Exp. Ther. 263, 318-326.
14. Cameron D. L. and Williams J. T. (1994) Cocaine inhibits GABA release in the VTA through endogenous 5-HT. J. Neurosci. 14, 6763-6767.
15. Cameron D. L. and Williams J. T. (1995) Opposing roles for dopamine and serotonin at presynaptic receptors in the ventral tegmental area. Clin. Exp. Pharmacol. Physiol. 22, 841-845.
16. Carroll M. E., Lac S. T., Asencio M. and Kragh R. (1990a) Fluoxetine reduces intravenous cocaine self-administration in rats. Pharmacol. Biochem. Behav. 35, 237-244.
17. Carroll M. E., Lac S. T., Asencio M. and Kragh R. (1990b) Intravenous cocaine self-administration is reduced by dietary 1-tryptophan. Psychopharmacol. 100, 293-300.
18. Cervo L., Rozio M., Ekalle-Soppo C. B., Carnovali F., Santangelo E. and Samanin R. (2002) Stimulation of serotonin1B receptors induces conditioned place aversion and facilitates cocaine place conditioning in rats. Psychopharmacol. 163, 142-150.
19. Chaouloff F., Courvoisier H., Moisan M. P. and Mormede P. (1999) GR 127935 reduced basal locomotor activity and prevents RU 14969-, but not D-amphetamine-induced hyperlocomotion, in the Wistar-Kyoto Hyperactive (WKHA) rat. Psychopharmacology 141, 326-331.
20. 1B receptor. Br. J. Pharmacol. 110, 1621-1629.
21. Chopin P. and Briley M. (1987) Animal models of anxiety: the effect of compounds that modify 5-HT neurotransmission. Trends Pharmacol. Sci. 8, 383-388.
22. 1B/D receptor ligands. Pharmacol. Ther. 62, 385-405.
23. Coccaro E. F., Siever L. J., Klar H., Maurer K., Rubenstein K., Cooper T. B., Mohs R. C. and Davis K. L. (1989) Serotonergic studies in affective and personality disorder patients: Correlates with behavioral aggression and impulsivity. Arch. General Psychiatry 46, 587-599.
24. Creese I. and Iversen S. D. (1973) Blockage of amphetamine-induced motor stimulation and stereotypy in the adult rat following neonatal treatment with 6-hydroxydopamine. Brain Res. 55, 369-382.
25. Crino P. B., Vogt B. A., Volicer L. and Wiley R. G. (1990) Cellular localization of serotonin 1A, 1B and uptake sites in cingulate cortex of the rat. J. Pharmacol. Exp. Ther. 252, 651-656.
26. Dackis C. A. and Gold M. S. (1985) New concepts in cocaine addiction: The dopamine depletion hypothesis. Neurosci. Biobehav. Rev. 9, 469-477.
27. 1B receptors in the regulation of extracellular serotonin and dopamine in the dorsal striatum of mice. Eur. J. Pharmacol. 476, 71-77.
28. 2 agonists. J. Pharacol. 89, 377-384.
29. 1B receptors in an animal model of depression. Neuropharmacology 30, 101-105.
30. Egan M. F., Wing L., Li R., Kirch D. G. and Wyatt R. J. (1994) Effects of chronic cocaine treatment on rat brain: long-term reduction in frontal cortical serotonin. Biol. Psychiatry 36, 637-640.
31. Filip M., Nowak E., Papla I. and Przegalinski E. (2001) Role of 5-hydroxytryptamine1B receptors and 5-hydroxytryptamine uptake inhibition in the cocaine-evoked discriminative stimulus effects in rats. J. Physiol. Pharmacol. 52, 249-263.
32. 1B receptor ligands microinjected into the ventral tegmental area on cocaine discrimination in rats. Eur. J. Pharmacol. 459, 239-245.
33. Filip M., Papla I., Nowak E., Jungersmith K. and Przegalinski E. (2002) Effects of serotonin (5-HT) (1B) receptor ligands, microinjected into accumbens subregions, on cocaine discrimination in rats. Naunyn Shmiedebergs Arch., Pharmacol. 366, 226-234.
34. Fishbein D. H., Lozovsky D. and Jaffee J. H. (1989) Impulsivity, aggression, and neuroendocrine responses to serotonergic stimulation in substance abusers. Biol. Psychiatry 25, 1049-1066.
35. 1B) agonists in the isolation-induced social behavioural deficit test. Neuropharmacology 30, 623-627.
36. Frankfurt M., Mendelson S. D., McKittrick C. R. and McEwen B. S. (1993) Alterations of serotonin receptor binding in the hypothalamus following acute denervation. Brain Res. 601, 349-352.
37. 1B agonist CP 93,129 facilitates striatal dopamine release in vivo. Synapse 15, 90-92.
38. Gawin F. H. and Ellinwood E. H. (1988) Cocaine and other stimulants: actions, abuse, and treatment. N. Engl. J. Med. 318, 1173-1182.
39. Gillin J. C., Pulvirenti L., Withers N., Golshan S. and Koob G. F. (1994) The effects of lisuride on mood, craving and sleep during acute withdrawal from cocaine and amphetamine: a preliminary report. Biol. Psychiatry 35, 843-849.
40. Guan X.-M. and McBride W. J. (1989) Serotonin microinfusion into the ventral tegmental area increases accumbens dopamine release. Brain Res. Bull. 23, 541-547.
41. Hartig P. R., Branchek T. A. and Weinshank R. L. (1992) A subfamily of 5-HT1D receptor genes. Trends Pharmacol. Sci. 13, 152-159.
42. Higgins G. A., Jordan C. C. and Skingle M. (1991) Evidence that the unilateral activation of 5-HT1D receptors in the substantia nigra of the guinea pig elicits contralateral rotation. Br. J. Pharmacol. 102, 305-310.
43. Hoyer D., Clarke D. E., Fozard J. R., Hartig P. R., Martin G. R., Mylecharane E. J., Saxena P. R. and Humphrey P. P. A. (1994) International union of pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol. Rev. 46, 157-203.
44. Iyer R. N. and Bradberry C. W. (1996) Serotonin-mediated increase in prefrontal cortex dopamine release: pharmacological characterization. J. Pharmacol. Exp. Ther. 277, 40-47.
45. 1b receptors block the GABAb synaptic potential in rat dopamine neurons. J. Neurosci. 12, 2000-2006.
46. 1 receptors modulate glutamate transmission in the ventral tegmental area. J. Neurosci. 15, 5379-5388.
47. Kalivas P. W. and Duffy P. (1998) Repeated cocaine administration alters extracellular glutamate in the ventral tegmental area. J. Neurochem. 70, 1497-1502.
48. Karasawa J.-i., Yoshimizu T. and Chaki S. (2006) A metabotropic glutamate 2/3 receptor antagonist, MGS0039, increases extracellular dopamine levels in the nucleus accumbens shell. Neurosci. Lett. 393, 127-130.
49. 1B receptor: binding studies in rat brain membranes. J. Neurochem. 58, 1268-1276.
50. Koob G. F. and Bloom F. E. (1988) Cellular and molecular mechanisms of drug dependence. Science 242, 715-723.
51. Koob G. F., Sanna P. P. and Bloom F. E. (1998) Neuroscience of addiction. Neuron 21, 467-476.
52. Kuhar M. L., Ritz M. C. and Boja J.W. (1991) The dopamine hypothesis of the reinforcing properties of cocaine. Trends Neurosci. 14, 299-302.
53. 1B antagonists by chemical modulation of 3-[3-(N,N-dimethylamino) propyl]-4-hydroxy-N-['4-(pyridin-4-yl) phenyl]benzamide (GR-55562). J. Med. Chem. 40, 3542-3550.
54. Loh E. A. and Roberts D. C. S. (1990) Break-points on a progressive ratio schedule reinforced by intravenous cocaine increase following depletion of forebrain serotonin. Psychopharmacol. 101, 262-266.
55. 1B/1D antagonist GR 127935. Mol. Pharmacol. 51, 755-763.
56. Macor J. E., Burkhart C. A., Heym J. H., Ives J. L., Lebel L. A., Newman M. E., Nielsen J. A., Ryan K., Schulz D.W., Torgesen L. K. and Koe B. K. (1990) 3-(1,2,5,6-Tetrahydropyrid-4-yl)-pyrrolo[3,2-b]pyrid-5-one: a potent and selective serotonin (5-HT1b) agonist and rotationally restricted phenolic analogue of 5-methoxy-3-(1, 2•, 6-tetrahydropyrid)4-yl) indole. J. Medical Chem. 33, 2087-93.
57. 1B binding sites in the rat suprachiasmatic nucleus. Brain Res. 663, 93-100.
58. 1B binding sites following 5,7-dihydroxytryptamine axotomoy in the adult rat. Brain Res. 623, 345-348.
59. Miller N. S., Summers G. L. and Gold M. S. (1993) Cocaine dependence: Alcohol and other drug dependence and withdrawal characteristics. J. Addict. Dis. 12, 25-35.
60. B receptors and the effects of baclofen in the mammalian central nervous system. Prog. Neurobiol. 46, 423-462.
61. Moeller F. G., Steinberg J. L., Petty F., Fulton M., Cherek D. R., Kramer G. and Garver D. L. (1994) Serotonin and impulsive/aggressive behavior in cocaine dependent subjects. Prog. Neuropsychopharmacol. Biol. Psychiatry 18, 1027-1035.
62. Morgan D., Liu Y. and Roberts D. C. S. (2005a) Rapid and persistent sensitization to the reinforcing effects of cocaine. Neuropsychopharmacol. (online publication 25 May 2005, doi: 10.1038/sj.npp.1300773).
63. Morgan D. and Roberts D. C. S. (2004) Sensitization to the reinforcing effects of cocaine following binge-abstinent self-administration. Neurosci. Biobehav. Rev. 27, 803-812.
64. Morgan D., Smith M. A. and Roberts D. C. S. (2005b) Binge self-administration and deprivation produces sensitization to the reinforcing effects of cocaine in rats. Psychopharmacol. 178, 309-316.
65. 1B auto- and heteroreceptors. Mol. Pharmacol. 58, 1271-1278.
66. 1B receptors. Eur. J. Neurosci. 10, 2371-2379.
67. 1B receptors in nucleus accumbens efferent sensitizes animals to cocaine. J. Neurosci. 22, 10 856-10 863.
68. 1B receptor subtypes in rat brain. Eur. J. Pharmacol. 281, 229-239.
69. Nisbet A. P. and Marsden C. A. (1984) Increased behavioural response to 5-methoxy-N,N-dimethyltryptamine but not to RU-24969 after intraventricular 5,7-dihydroxytryptamine administration. Eur. J. Pharmacol. 104, 177-180.
70. 1B receptors in the ventral tegmental area modulate cocaine-induced increases in nucleus accumbens dopamine levels. J. Pharmacol. Exp. Ther. 311, 711-719.
71. O'Neill M. F., Fernandez A. G. and Palacios J. M. (1996) GR 127935 blocks the locomotor and antidepressant-like effects of RU 24969 and the action of antidepressants in the mouse tail suspension test. Pharmacol. Biochem. Behav. 53, 535-539.
72. 1 agonist RU 24969 in globus-pallidus-lesioned rats. Neurosci. Lett. 67, 113-118.
73. 1 agonist RU 24969 and effects on dopaminergic behaviour. Eur. J. Pharmacol. 139, 205-214.
74. 1B receptors in the brain of the rat. J. Pharmacol. Exp. Ther. 244, 144-153.
75. Parsons L. H., Koob G. F. and Weiss F. (1995) Serotonin dysfunction in the nucleus accumbens of rats during withdrawal after unlimited access to intravenous cocaine. J. Pharmacol. Exp. Ther. 274, 1182-1191.
76. 1B/1A receptor agonist, potentiates cocaine-induced increases in nucleus accumbens dopamine. Synapse 32, 132-135.
77. Parsons L. H., Weiss F. and Koob G. F. (1996) Serotonin-1B receptor stimulation enhances dopamine-mediated reinforcement. Psychopharmacol. 128, 150-160.
78. Parsons L. H., Weiss F. and Koob G. F. (1998) Serotonin1B receptor stimulation enhances cocaine reinforcement: behavioral and neurochemical studies in rats. J. Neurosci. 18, 10 078-10 089.
79. Paxinos G. and Watson C. (1998) The Rat Brain in Stereotaxic Coordinates, 4th edn. Academic Press, San Diego.
80. Pellow S., Chopin P., File S. E. and Briley M. (1985) Validation of open: closed arm entries in an elevated plus maze as a measure of anxiety in the rat. J. Neurosci. Meth. 14, 149-167.
81. Pierce R. C., Bell K., Duffy P. and Kalivas P. W. (1996) Repeated cocaine augments excitatory amino acid transmission in the nucleus accumbens only in rats having developed behavioral sensitization. J. Neurosci. 16, 1550-1560.
82. Potashner S. J. (1979) Baclofen: effects on amino acid release and metabolism in slices of guinea pig cerebral cortex. J. Neurochem. 32, 103-109.
83. 1B receptor binding sites in the central nervous system. Neuropsychopharmacology 10, 259-264.
84. 1B receptors in the rat brain. Neuroscience Lett. 351, 169-172.
85. 1B receptor ligands microinjected into the accumbal shell or core on the cocaine-induced locomotor hyperactivity in rats. J. Physiol. Pharmacol. 53, 383-394.
86. 1B receptor ligands microinjected into the accumbal shell or core on the sensitization of cocaine in rats. Eur. Neuropsychopharmacol. 12, 387-396.
87. 1B receptor ligands microinjected into the ventral tegmental area on the locomotor and sensitizing effects of cocaine in rats. Eur Neuropsychopharmacol. 14, 217-225.
88. 1B receptor ligands on cocaine sensitization in rats. Behav. Pharmacol. 12, 109-116.
89. Rahman S. and McBride W. J. (2002) Involvement of GABA and cholinergic receptors in the nucleus accumbens on feedback of somatodendritic dopamine release in the ventral tegmental area. J. Neurochem. 80, 646-654.
90. Ramboz S., Saudou F., Amara D. A., Belzung C., Segu L., Misslin R., Buhot M. C. and Hen R. (1996) 5-HT1B receptor knock out - behavioral consequences. Behav. Brain Res. 73, 305-312.
91. Rempel N. L., Callaway C. W. and Geyer M. A. (1993) Serotonin 1B receptor activation mimics behavioral effects of presynaptic serotonin release. Neuropsychopharmacology 8, 201-211.
92. 1B receptors modulate release of [3H]dopamine from rat striatal synaptosomes. Naunyn-Schmiedeberg's Arch. Pharmacol. 359, 40-47.
93. Satel S. L., Krystal J. H., Delgado P. L., Kosten T. R. and Charney D. S. (1995) Tryptophan depletion and attenuation of cue-induced craving for cocaine. Am. J. Psychiatry 152, 778-783.
94. 1B receptors. Science 265, 1875-1878.
95. 1B mRNA in rat brain. Mol. Psych. 4, 572-579.
96. B receptors within the rat dorsolateral septal nucleus. J. Pharmacol. Exp. Ther. 280, 129-137.
97. Shoji S., Simms D., Yamada K. and Gallagher J. P. (1998) Cocaine administered in vitro to brain slices from rats treated with cocaine chronically in vivo results in a g-aminobutyric acid receptor-mediated hyperpolarization recorded from the dorsolateral septum. J. Pharmacol. Exp. Ther. 286, 509-518.
98. Solomon R. L. and Corbit J. D. (1974) An opponent-process theory of motivation. I. Temporal dynamics of affect. Psychol. Rev. 81, 119-145.
99. Spealman R. D. (1993) Modification of behavioral effects of cocaine by selective serotonin and dopamine uptake inhibitors in squirrel monkeys. Psychopharmacol. 112, 93-99.
100. Van de Kar L. D., Carnes M., Maslowski R. J., Bonadonna A. M., Rittenhouse P. A., Kunimoto K., Piechowski R. A. and Bethea C. L. (1989) Neuroendocrine evidence for denervation supersensitivity of serotonin receptors: effects of the 5-HT agonist RU 24969 on corticotropin, corticosterone, prolactin and renin secretion. J. Pharmacol. Exp. Ther. 251, 428-434.
101. Walsh S. L., Preston K. L., Sullivan J. T., Fromme R. and Bigelow G. E. (1994) Fluoxetine alters the effects of intravenous cocaine in humans. J. Clin. Psychopharmacol. 14, 396-407.
102. Weiss F., Parsons L. H. and Markou A. (1995) Neurochemistry of cocaine withdrawal. In: Hammer, R. P., ed. The Neurobiology of Cocaine: Cellular and Molecular Mechanisms. CRC Press, Boca Raton, FL, pp. 163-180.
103. Weissmann D., Mach E., Oberlander C., Demassey Y. and Pujol J.-F. (1986) Evidence for hyperdensity of 5HT1B binding sites in the substantia nigra of the rat after 5,7-dihydoxytryptamine intraventricular injection. Neurochem. Int. 9, 191-200.
104. Wise R. A. (1984) Neural mechanisms of the reinforcing action of cocaine. In: Cocaine: Pharmacology, Effects and Treatment of Abuse (NIDA Research Monograph Series (Grabowsky, J., ed. ), pp. 15-33. Vol. 50. United States. Government Printing Office, Washington, D.C., USA
105. Wu Y.-N., Shen K.-Z. and Johnson S. W. (1999) Presynaptic inhibition preferentially reduces in NMDA receptor-mediated component of transmission in rat midbrain dopamine neurons. Br. J. Pharmacol. 127, 1422-1430.
106. Xi Z.-X., Ramamoorthy S., Shen H., Lake R., Samuvel D. J. and Kalivas P. W. (2003) GABA transmission in the nucleus accumbens is altered after withdrawal from repeated cocaine. J. Neurosci. 23, 3498-3505.
107. 1B/1D receptors in the mesolimbic dopamine system increases dopamine release from the nucleus accumbens: a microdialysis study. Eur. J. Pharmacol. 418, 55-64.
108. Yan Q. S. and Yan S. E. (2001b) Serotonin-1B receptor-mediated inhibition of [(3) H]GABA release from rat ventral tegmental area slices. J. Neurochem. 79, 914-922.
109. 1B receptors within the ventral tegmental area in regulation of mesolimbic dopaminergic neuronal activity via GABA mechanisms: a study with dual-probe microdialysis. Brain Res. 1021, 82-91.
110. Zapata A., Chefer V. I., Ator R., Shippenberg T. S. and Rocha B. A. (2003) Behavioral sensitization and enhanced dopamine response in the nucleus accumbens after intravenous cocaine self-administration in mice. Eur. J. Neurosci. 17, 590-596.