Efficient modification of alpha-synuclein serine 129 by protein kinase CK1 requires phosphorylation of tyrosine 125 as a priming event

ACS Chemical Neuroscience

Volumn 5, Issue 12, 2014, Pages 1203-1208

  Kosten, Jonas ^a   Binolfi, Andres ^a   Stuiver, Marchel ^a   Verzini, Silvia ^a,b   Theillet, Francois Xavier ^a   Bekei, Beata ^a   Van Rossum, Marleen ^a   Selenko, Philipp ^a  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b UNIVERSITY OF POTSDAM   (Germany)

Author keywords

Alpha synuclein; Casein kinase 1; Kinetics; NMR; Parkinson's disease; Phosphorylation

Indexed keywords

ALPHA SYNUCLEIN; CASEIN KINASE I; FOCAL ADHESION KINASE 1; PROTEIN KINASE FYN; PROTEIN KINASE LYN; PROTEIN KINASE YES; PROTEIN TYROSINE KINASE; SERINE; GREEN FLUORESCENT PROTEIN; TYROSINE;

ANIMAL CELL; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VIVO STUDY; NITROGEN NUCLEAR MAGNETIC RESONANCE; NONHUMAN; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTON NUCLEAR MAGNETIC RESONANCE; GENETIC TRANSFECTION; GENETICS; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHORYLATION; PHYSIOLOGY; TRANSFORMED CELL LINE;

MAMMALIA;

ALPHA-SYNUCLEIN; CASEIN KINASE I; CELL LINE, TRANSFORMED; GREEN FLUORESCENT PROTEINS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHORYLATION; SERINE; TRANSFECTION; TYROSINE;

EID: 84918572460     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn5002254     Document Type: Article

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