메뉴 건너뛰기




Volumn 62, Issue 1, 2015, Pages 131-139

Increased autophagy sustains the survival and pro-tumourigenic effects of neutrophils in human hepatocellular carcinoma

Author keywords

Autophagy; Hepatocellular carcinoma; Neutrophil; Pro tumourigenic properties; Survival

Indexed keywords

CASPASE 3; GELATINASE B; HYALURONIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LC3 PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; ONCOSTATIN M; PROTEIN; PROTEIN MCL 1; UNCLASSIFIED DRUG;

EID: 84918570174     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.08.023     Document Type: Article
Times cited : (91)

References (35)
  • 1
    • 79960829290 scopus 로고    scopus 로고
    • Neutrophils in the activation and regulation of innate and adaptive immunity
    • A. Mantovani, M.A. Cassatella, C. Costantini, and S. Jaillon Neutrophils in the activation and regulation of innate and adaptive immunity Nat Rev Immunol 11 2011 519 531
    • (2011) Nat Rev Immunol , vol.11 , pp. 519-531
    • Mantovani, A.1    Cassatella, M.A.2    Costantini, C.3    Jaillon, S.4
  • 2
    • 33344468233 scopus 로고    scopus 로고
    • Neutrophils and immunity: Challenges and opportunities
    • C. Nathan Neutrophils and immunity: challenges and opportunities Nat Rev Immunol 6 2006 173 182
    • (2006) Nat Rev Immunol , vol.6 , pp. 173-182
    • Nathan, C.1
  • 5
    • 47949090079 scopus 로고    scopus 로고
    • The role of myeloid cells in the promotion of tumour angiogenesis
    • C. Murdoch, M. Muthana, S.B. Coffelt, and C.E. Lewis The role of myeloid cells in the promotion of tumour angiogenesis Nat Rev Cancer 8 2008 618 631
    • (2008) Nat Rev Cancer , vol.8 , pp. 618-631
    • Murdoch, C.1    Muthana, M.2    Coffelt, S.B.3    Lewis, C.E.4
  • 6
    • 34547113798 scopus 로고    scopus 로고
    • Tumour-derived hyaluronan induces formation of immunosuppressive macrophages through transient early activation of monocytes
    • D.M. Kuang, Y. Wu, N. Chen, J. Cheng, S.M. Zhuang, and L. Zheng Tumour-derived hyaluronan induces formation of immunosuppressive macrophages through transient early activation of monocytes Blood 110 2007 587 595
    • (2007) Blood , vol.110 , pp. 587-595
    • Kuang, D.M.1    Wu, Y.2    Chen, N.3    Cheng, J.4    Zhuang, S.M.5    Zheng, L.6
  • 7
    • 67449110979 scopus 로고    scopus 로고
    • Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1
    • D.M. Kuang, Q. Zhao, C. Peng, J. Xu, J.P. Zhang, and C. Wu Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1 J Exp Med 206 2009 1327 1337
    • (2009) J Exp Med , vol.206 , pp. 1327-1337
    • Kuang, D.M.1    Zhao, Q.2    Peng, C.3    Xu, J.4    Zhang, J.P.5    Wu, C.6
  • 8
    • 73449111925 scopus 로고    scopus 로고
    • Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells
    • D.M. Kuang, C. Peng, Q. Zhao, Y. Wu, M.S. Chen, and L. Zheng Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells Hepatology 51 2010 154 164
    • (2010) Hepatology , vol.51 , pp. 154-164
    • Kuang, D.M.1    Peng, C.2    Zhao, Q.3    Wu, Y.4    Chen, M.S.5    Zheng, L.6
  • 9
    • 79953328298 scopus 로고    scopus 로고
    • Tumor-Associated neutrophils: New targets for cancer therapy
    • A.D. Gregory, and M.A. Houghton Tumor-Associated neutrophils: new targets for cancer therapy Cancer Res 71 2011 2411 2416
    • (2011) Cancer Res , vol.71 , pp. 2411-2416
    • Gregory, A.D.1    Houghton, M.A.2
  • 11
    • 70350455089 scopus 로고    scopus 로고
    • Presence of intratumoral neutrophils is an independent prognostic factor in localized renal cell carcinoma
    • H.K. Jensen, F. Donskov, N. Marcussen, M. Nordsmark, F. Lundbeck, and H. von der Maase Presence of intratumoral neutrophils is an independent prognostic factor in localized renal cell carcinoma J Clin Oncol 27 2009 4709 4717
    • (2009) J Clin Oncol , vol.27 , pp. 4709-4717
    • Jensen, H.K.1    Donskov, F.2    Marcussen, N.3    Nordsmark, M.4    Lundbeck, F.5    Von Der Maase, H.6
  • 12
    • 69249242897 scopus 로고    scopus 로고
    • The Yin-Yang of tumor-Associated neutrophils
    • A. Mantovani The Yin-Yang of tumor-Associated neutrophils Cancer Cell 16 2009 173 174
    • (2009) Cancer Cell , vol.16 , pp. 173-174
    • Mantovani, A.1
  • 13
    • 84863380159 scopus 로고    scopus 로고
    • Peritumoral neutrophils link inflammatory response to disease progression by fostering angiogenesis in hepatocellular carcinoma
    • D.M. Kuang, Q. Zhao, Y. Wu, C. Peng, J. Wang, and Z. Xu Peritumoral neutrophils link inflammatory response to disease progression by fostering angiogenesis in hepatocellular carcinoma J Hepatol 185 2011 1544 1549
    • (2011) J Hepatol , vol.185 , pp. 1544-1549
    • Kuang, D.M.1    Zhao, Q.2    Wu, Y.3    Peng, C.4    Wang, J.5    Xu, Z.6
  • 14
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Beth Levine, and Guido Kroemer Autophagy in the pathogenesis of disease Cell 132 2008 27 32
    • (2008) Cell , vol.132 , pp. 27-32
    • Levine, B.1    Kroemer, G.2
  • 15
    • 84880376355 scopus 로고    scopus 로고
    • Emerging regulation and functions of autophagy
    • P. Boya, F. Reggiori, and P. Codogno Emerging regulation and functions of autophagy Nat Cell Biol 15 2013 713 720
    • (2013) Nat Cell Biol , vol.15 , pp. 713-720
    • Boya, P.1    Reggiori, F.2    Codogno, P.3
  • 16
    • 72549095406 scopus 로고    scopus 로고
    • Regulation mechanisms and signaling pathways of Autophagy
    • C. He, and D.J. Klionsky Regulation mechanisms and signaling pathways of Autophagy Ann Rev Genet 43 2009 67 93
    • (2009) Ann Rev Genet , vol.43 , pp. 67-93
    • He, C.1    Klionsky, D.J.2
  • 17
    • 78649338141 scopus 로고    scopus 로고
    • Autophagy and the integrated stress response
    • G. Kroemer, G. Mariño, and B. Levine Autophagy and the integrated stress response Mol Cell 40 2010 280 293
    • (2010) Mol Cell , vol.40 , pp. 280-293
    • Kroemer, G.1    Mariño, G.2    Levine, B.3
  • 18
    • 33745713171 scopus 로고    scopus 로고
    • Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
    • K. Degenhardt, R. Mathew, B. Beaudoin, K. Bray, D. Anderson, and G. Chen Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis Cancer Cell 10 2006 51 64
    • (2006) Cancer Cell , vol.10 , pp. 51-64
    • Degenhardt, K.1    Mathew, R.2    Beaudoin, B.3    Bray, K.4    Anderson, D.5    Chen, G.6
  • 19
    • 80052306066 scopus 로고    scopus 로고
    • Autophagy protects breast cancer cells from epirubicin-induced apoptosis and facilitates epirubicin-resistance development
    • W.L. Sun, J. Chen, Y.P. Wang, and H. Zheng Autophagy protects breast cancer cells from epirubicin-induced apoptosis and facilitates epirubicin-resistance development Autophagy 7 2011 1035 1044
    • (2011) Autophagy , vol.7 , pp. 1035-1044
    • Sun, W.L.1    Chen, J.2    Wang, Y.P.3    Zheng, H.4
  • 21
    • 84874459051 scopus 로고    scopus 로고
    • Monocyte/macrophage-elicited natural killer cell dysfunction in hepatocellular carcinoma is mediated by CD48/2B4 interactions
    • Y. Wu, D.M. Kuang, W.D. Pan, Y.L. Wan, X.M. Lao, and D. Wang Monocyte/macrophage-elicited natural killer cell dysfunction in hepatocellular carcinoma is mediated by CD48/2B4 interactions Hepatology 57 2013 1107 1116
    • (2013) Hepatology , vol.57 , pp. 1107-1116
    • Wu, Y.1    Kuang, D.M.2    Pan, W.D.3    Wan, Y.L.4    Lao, X.M.5    Wang, D.6
  • 22
    • 84863012436 scopus 로고    scopus 로고
    • Activated CD69+ T cells foster immune privilege by regulating IDO expression in tumor-Associated macrophages
    • Q. Zhao, D.M. Kuang, Y. Wu, X. Xiao, X.F. Li, and T.J. Li Activated CD69+ T cells foster immune privilege by regulating IDO expression in tumor-Associated macrophages J Immunol 188 2012 1117 1124
    • (2012) J Immunol , vol.188 , pp. 1117-1124
    • Zhao, Q.1    Kuang, D.M.2    Wu, Y.3    Xiao, X.4    Li, X.F.5    Li, T.J.6
  • 23
    • 30744448647 scopus 로고    scopus 로고
    • Extracellular acidosis induces neutrophil activation by a mechanism dependent on activation of phosphatidylinositol 3-kinase/Akt and ERK Pathways
    • D. Martínez, M. Vermeulen, A. Trevani, A. Ceballos, J. Sabatté, and R. Gamberale Extracellular acidosis induces neutrophil activation by a mechanism dependent on activation of phosphatidylinositol 3-kinase/Akt and ERK Pathways J Immunol 176 2006 1163 1171
    • (2006) J Immunol , vol.176 , pp. 1163-1171
    • Martínez, D.1    Vermeulen, M.2    Trevani, A.3    Ceballos, A.4    Sabatté, J.5    Gamberale, R.6
  • 24
    • 77952751229 scopus 로고    scopus 로고
    • Lysophosphatidylcholine increases neutrophil bactericidal activity by enhancement of azurophil granule-phagosome fusion via Glycine·GlyRα2/TRPM2/p38 MAPK signaling
    • C.W. Hong, T.K. Kim, H.Y. Ham, J.S. Nam, Y.H. Kim, and H. Zheng Lysophosphatidylcholine increases neutrophil bactericidal activity by enhancement of azurophil granule-phagosome fusion via Glycine·GlyRα2/TRPM2/p38 MAPK signaling J Immunol 184 2010 4401 4413
    • (2010) J Immunol , vol.184 , pp. 4401-4413
    • Hong, C.W.1    Kim, T.K.2    Ham, H.Y.3    Nam, J.S.4    Kim, Y.H.5    Zheng, H.6
  • 25
    • 33244498163 scopus 로고    scopus 로고
    • Neutrophil adhesion to endothelial cells induced by platelet factor 4 requires sequential activation of Ras, Syk, and JNK MAP kinases
    • B. Kasper, E. Brandt, M. Ernst, and F. Petersen Neutrophil adhesion to endothelial cells induced by platelet factor 4 requires sequential activation of Ras, Syk, and JNK MAP kinases Blood 107 2006 1768 1775
    • (2006) Blood , vol.107 , pp. 1768-1775
    • Kasper, B.1    Brandt, E.2    Ernst, M.3    Petersen, F.4
  • 26
    • 33750284176 scopus 로고    scopus 로고
    • Autophagy in cancer: Good, bad, or both?
    • M.M. Hippert, P.S. O'Toole, and A. Thorburn Autophagy in cancer: good, bad, or both? Cancer Res 66 2006 9349 9351
    • (2006) Cancer Res , vol.66 , pp. 9349-9351
    • Hippert, M.M.1    O'Toole, P.S.2    Thorburn, A.3
  • 27
    • 56449107131 scopus 로고    scopus 로고
    • Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma
    • Z.B. Ding, Y.H. Shi, J. Zhou, S.J. Qiu, Y. Xu, and Z. Dai Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma Cancer Res 68 2008 9167 9175
    • (2008) Cancer Res , vol.68 , pp. 9167-9175
    • Ding, Z.B.1    Shi, Y.H.2    Zhou, J.3    Qiu, S.J.4    Xu, Y.5    Dai, Z.6
  • 28
    • 25444497706 scopus 로고    scopus 로고
    • Breast cancer cells stimulate neutrophils to produce oncostatin M: Potential implications for tumor progression
    • M.M. Queen, R.E. Ryan, R.G. Holzer, C.R. Keller-Peck, and C.L. Jorcyk Breast cancer cells stimulate neutrophils to produce oncostatin M: potential implications for tumor progression Cancer Res 65 2005 8896 8904
    • (2005) Cancer Res , vol.65 , pp. 8896-8904
    • Queen, M.M.1    Ryan, R.E.2    Holzer, R.G.3    Keller-Peck, C.R.4    Jorcyk, C.L.5
  • 30
    • 83355163381 scopus 로고    scopus 로고
    • TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation
    • P.K. Anand, S.W. Tait, M. Lamkanfi, A.O. Amer, G. Nunez, and G. Pagès TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation J Biol Chem 286 2011 42981 42991
    • (2011) J Biol Chem , vol.286 , pp. 42981-42991
    • Anand, P.K.1    Tait, S.W.2    Lamkanfi, M.3    Amer, A.O.4    Nunez, G.5    Pagès, G.6
  • 31
    • 3142704153 scopus 로고    scopus 로고
    • Delayed neutrophil apoptosis in sepsis is associated with maintenance of mitochondrial transmembrane potential and reduced caspase-9 activity
    • R. Taneja, J. Parodo, S.H. Jia, A. Kapus, O.D. Rotstein, and J.C. Marshall Delayed neutrophil apoptosis in sepsis is associated with maintenance of mitochondrial transmembrane potential and reduced caspase-9 activity Crit Care Med 32 2004 1460 1469
    • (2004) Crit Care Med , vol.32 , pp. 1460-1469
    • Taneja, R.1    Parodo, J.2    Jia, S.H.3    Kapus, A.4    Rotstein, O.D.5    Marshall, J.C.6
  • 33
    • 79951642032 scopus 로고    scopus 로고
    • Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
    • K. Nakahira, J.A. Haspel, V.A. Rathinam, S.J. Lee, T. Dolinay, and H.C. Lam Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome Nat Immunol 8 2011 222 230
    • (2011) Nat Immunol , vol.8 , pp. 222-230
    • Nakahira, K.1    Haspel, J.A.2    Rathinam, V.A.3    Lee, S.J.4    Dolinay, T.5    Lam, H.C.6
  • 34
    • 84867773087 scopus 로고    scopus 로고
    • Mitophagy: Mechanisms, pathophysiological roles, and analysis
    • W.X. Ding, and X.M. Yin Mitophagy: mechanisms, pathophysiological roles, and analysis Biol Chem 393 2012 547 564
    • (2012) Biol Chem , vol.393 , pp. 547-564
    • Ding, W.X.1    Yin, X.M.2
  • 35
    • 79958025243 scopus 로고    scopus 로고
    • Extra domain A of fibronectin primes leukotriene biosynthesis and stimulates neutrophil migration through activation of Toll-like receptor 4
    • J.S. Lefebvre, T. Lévesque, S. Picard, G. Paré, A. Gravel, and L. Flamand Extra domain A of fibronectin primes leukotriene biosynthesis and stimulates neutrophil migration through activation of Toll-like receptor 4 Arthritis Rheum 63 2011 1527 1533
    • (2011) Arthritis Rheum , vol.63 , pp. 1527-1533
    • Lefebvre, J.S.1    Lévesque, T.2    Picard, S.3    Paré, G.4    Gravel, A.5    Flamand, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.