Restorative effect and mechanism of mecobalamin on sciatic nerve crush injury in mice

Neural Regeneration Research

Volumn 9, Issue 22, 2014, Pages 1979-1984

  Gan, Lin ^a   Qian, Min Quan ^a   Shi, Ke Qin ^a   Chen, Gang ^a   Gu, Yang Lin ^a   Du, Wei ^a   Zhu, Guo Xing ^a  

^a WUXI NO 2 PEOPLE S HOSPITAL   (China)

Author keywords

Gene expression; Mecobalamin; Molecular mechanism; Nerve regeneration; Nerve repair; Neural regeneration; Neuroprotective effect; Neurotrophic factor; Peripheral nerve injury; Sciatic nerve; Vitamin B12

Indexed keywords

MECOBALAMIN; MESSENGER RNA; NEUROMODULIN; NEUROTROPHIC FACTOR;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRUSH TRAUMA; DRUG MEGADOSE; GENE EXPRESSION; INVESTIGATIVE PROCEDURES; LOW DRUG DOSE; MALE; MORPHOMETRICS; MOTOR PERFORMANCE; MOUSE; MUSCLE ATROPHY; MUSCLE CELL; MYELIN SHEATH; NERVE FIBER DEGENERATION; NERVE FUNCTION; NERVE GROWTH; NERVE REGENERATION; NONHUMAN; PAW LENGTH; PHYSICAL PARAMETERS; REAL TIME POLYMERASE CHAIN REACTION; SCIATIC NERVE; SCIATIC NERVE CRUSH INJURY; SCIATIC NERVE INJURY; SPINAL GANGLION; TOE SPREAD; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; WALKING TRACK ANALYSIS;

EID: 84918522822     PISSN: 16735374     EISSN: 18767958     Source Type: Journal    
DOI: 10.4103/1673-5374.145379     Document Type: Article

References (48)

1. Allodi I, Udina E, Navarro X (2012) Specificity of peripheral nerve regeneration: interactions at the axon level. Prog Neurobiol 98: 16-37.
2. Atlasi MA, Mehdizadeh M, Bahadori MH, Joghataei MT (2009) Morphological identification of cell death in dorsal root ganglion neurons following peripheral nerve injury and repair in adult rat. Iran Biomed J 13: 65-72.
3. Bijwaard KE, Aguilera NS, Monczak Y, Trudel M, Taubenberger JK, Lichy JH (2001) Quantitative real-time reverse transcription-PCR assay for cyclin D1 expression: utility in the diagnosis of mantle cell lymphoma. Clin Chem 47: 195-201.
4. Burland M, Paris L, Quintana P, Bec JM, Diouloufet L, Sar C, Boukhaddaoui H, Charlot B, Braga Silva J, Chammas M, Sieso V, Valmier J, Bardin F (2014) Neurite growth acceleration of adult dorsal root ganglion neurons illuminated by low-level light emitting diode light at 645 nm. J Biophotonics 9999: 9999.
5. Cai S, Shea GK, Tsui AY, Chan YS, Shum DK (2011) Derivation of clinically applicable schwann cells from bone marrow stromal cells for neural repair and regeneration. CNS Neurol Disord Drug Targets 10: 500-508.
6. Chen X, Yang Y, Yao J, Lin W, Li Y, Chen Y, Gao Y, Yang Y, Gu X, Wang X (2011) Bone marrow stromal cells-loaded chitosan conduits promote repair of complete transection injury in rat spinal cord. J Mater Sci Mater Med 22: 2347-2356.
7. Chen Y, Zhao C, Zhang C, Luo L, Yu G (2012) Influence of chronic intermittent hypoxia on growth associated protein 43 expression in the hippocampus of young rats. Neural Regen Res 7: 1241-1246.
8. Cui Q (2006) Actions of neurotrophic factors and their signaling pathways in neuronal survival and axonal regeneration. Mol Neurobiol 33: 155-179.
9. Dadon-Nachum M, Melamed E, Offen D (2011) Stem cells treatment for sciatic nerve injury. Expert Opin Biol Ther 11: 1591-1597.
10. Daly W, Yao L, Zeugolis D, Windebank A, Pandit A (2012) A biomaterials approach to peripheral nerve regeneration: bridging the peripheral nerve gap and enhancing functional recovery. J R Soc Interface 9: 202-221.
11. Danielsen N (1989) Neurotrophic factors and nerve regeneration-an overview. Lakartidningen 86: 2106-2107.
12. Gordon T (2009) The role of neurotrophic factors in nerve regeneration. Neurosurg Focus 26: E3.
13. Grumbles RM, Sesodia S, Wood PM, Thomas CK (2009) Neurotrophic factors improve motoneuron survival and function of muscle reinnervated by embryonic neurons. J Neuropathol Exp Neurol 68: 736-746.
14. Gu X, Ding F, Yang Y, Liu J (2011) Construction of tissue engineered nerve grafts and their application in peripheral nerve regeneration. Prog Neurobiol 93: 204-230.
15. Hoyng SA, Tannemaat MR, De Winter F, Verhaagen J, Malessy MJ (2011) Nerve surgery and gene therapy: a neurobiological and clinical perspective. J Hand Surg Eur Vol 36: 735-746.
16. Huang PJ, Mao XH, Wang YP (2011) Electrophysiological changes in diabetic peripheral neuropathy patients of different Chinese medicine syndrome types intervened by naoxintong and mecobalamin. Zhongguo Zhong Xi Yi Jie He Za Zhi 31: 1051-1056.
17. Izumi K, Fujise T, Inoue K, Mori H, Yamazaki K, Hongou Y, Takagi S, Yamanouchi H, Ashida K, Anzai K (2013) Mecobalamin improved pernicious anemia in an elderly individual with Hashimoto's disease and diabetes mellitus. Nihon Ronen Igakkai Zasshi 50: 542-545.
18. Jacob JM, Zhou Q, Liu Y (2000) Novel method for the labeling of distant neuromuscular junctions. J Neurosci Res 61: 61-66.
19. Johnson IP, Sears TA (2013) Target-dependence of sensory neurons: an ultrastructural comparison of axotomised dorsal root ganglion neurons with allowed or denied reinnervation of peripheral targets. Neuroscience 228: 163-178.
20. Kingham PJ, Kolar MK, Novikova LN, Novikov LN, Wiberg M (2014) Stimulating the neurotrophic and angiogenic properties of human adipose-derived stem cells enhances nerve repair. Stem Cells Dev 23: 741-754.
21. Kocaoglu C, Akin F, Caksen H, Boke SB, Arslan S, Aygun S (2014) Cerebral atrophy in a vitamin B12-deficient infant of a vegetarian mother. J Health Popul Nutr 32: 367-371.
22. Lee EJ, Xu L, Kim GH, Kang SK, Lee SW, Park SH, Kim S, Choi TH, Kim HS (2012) Regeneration of peripheral nerves by transplanted sphere of human mesenchymal stem cells derived from embryonic stem cells. Biomaterials 33: 7039-7046.
23. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25: 402-408.
24. Madduri S, Feldman K, Tervoort T, Papaloizos M, Gander B (2010) Collagen nerve conduits releasing the neurotrophic factors GDNF and NGF. J Control Release 143: 168-174.
25. Mafi P, Hindocha S, Phital M, Sale M (2012) Advances of peripheral nerve repair techniques to improve hand function: a systematic review of literature. Open Orthop J 6: 60-68.
26. Marconi S, Castiglione G, Turano E, Bissolotti G, Angiari S, Farinazzo A, Constantin G, Bedogni G, Bedogni A, Bonetti B (2012) Human adipose-derived mesenchymal stem cells systemically injected promote peripheral nerve regeneration in the mouse model of sciatic crush. Tissue Eng Part A 18: 1264-1272.
27. Matsushita M, Nakagawa H, Namiki S, Ikeda Y, Kaiho Y, Kawamorita N, Ito A, Ishidoya S, Saito S, Arai Y (2009) Effects of urinary function and erectile function on the use of mecobalamin after nerve sparing radical prostatectomy. Nihon Hinyokika Gakkai Zasshi 100: 7-11.
28. Meziere A, Audureau E, Vairelles S, Krypciak S, Dicko M, Monie M, Giraudier S (2014) B12 deficiency increases with age in hospitalized patients: a study on 14, 904 samples. J Gerontol A Biol Sci Med Sci [Epub ahead of print].
29. Rizos E, Papathanasiou MA, Michalopoulou PG, Laskos E, Mazioti A, Kastania A, Vasilopoulou K, Nikolaidou P, Margaritis D, Papageorgiou C, Liappas I (2014) A longitudinal study of alterations of hippocampal volumes and serum BDNF levels in association to atypical antipsychotics in a sample of first-episode patients with schizophrenia. PLoS One 9: e87997.
30. Rustemeyer J, Dicke U (2009) Correlation of three sciatic functional indices with histomorphometric findings in a rat sciatic nerve allograft repair model. Microsurgery 29: 560-567.
31. Saijilafu, Zhou FQ (2012) Genetic study of axon regeneration with cultured adult dorsal root ganglion neurons. J Vis Exp 4141.
32. Saleh A, Roy Chowdhury SK, Smith DR, Balakrishnan S, Tessler L, Martens C, Morrow D, Schartner E, Frizzi KE, Calcutt NA, Fernyhough P (2013) Ciliary neurotrophic factor activates NF-kappaB to enhance mitochondrial bioenergetics and prevent neuropathy in sensory neurons of streptozotocin-induced diabetic rodents. Neuropharmacology 65: 65-73.
33. Tsai MS, Ko YH, Hsu WM, Liang JT, Lai HS, Lee PH, Chang KC (2011) Enhanced aortic nerve growth factor expression and nerve sprouting in rats following gastric perforation. J Surg Res 171: 205-211.
34. Unezaki S, Yoshii S, Mabuchi T, Saito A, Ito S (2009) Effects of neurotrophic factors on nerve regeneration monitored by in vivo imaging in thy1-YFP transgenic mice. J Neurosci Methods 178: 308-315.
35. Valiente-Gomez A, Amann BL, Marmol F, Oliveira C, Messeguer A, Lafuente A, Pomarol-Clotet E, Bernardo Arroyo M (2014) Comparison of serum BDNF levels in deficit and nondeficit chronic schizophrenia and healthy controls. Psychiatry Res [Epub ahead of print].
36. Wan L, Xia R, Ding W (2010) Short-term low-frequency electrical stimulation enhanced remyelination of injured peripheral nerves by inducing the promyelination effect of brain-derived neurotrophic factor on Schwann cell polarization. J Neurosci Res 88: 2578-2587.
37. Wang K, Zhou F, Zhu L, Zhu X, Zhang K, Zhu L (2014a) High level soluble expression, purification, and characterization of human ciliary neuronotrophic factor in Escherichia coli by single protein production system. Protein Expr Purif 96: 8-13.
38. Wang LM, Tang JC, Xin LW, Li Q, Zhou YQ, Chen H, Gu ZL (2012) Effects of nerve growth factor injection via different ways on repair and regeneration of the sciatic nerve after its anastomosis. Zhongguo Zuzhi Gongcheng Yanjiu 16: 1169-1172.
39. Wang XC, Xu DJ, Chen GH, Xia Q, Liu LN (2014b) Association of 2 neurotrophic factor polymorphisms with efficacy of paroxetine in patients with major depressive disorder in a chinese population. Ther Drug Monit 36: 612-617.
40. Wu RH, Xu M, Zhao PF, Liu M (2012) The mRNA alteration and correlation of Calpains and FoxOs during gastrocnemius muscle atrophy induced by sciatic nerve injury and cardiotoxin injection. Zhongguo Zuzhi Gongcheng Yanjiu 16: 1173-1179.
41. Xiao J, Wong AW, Willingham MM, Kaasinen SK, Hendry IA, Howitt J, Putz U, Barrett GL, Kilpatrick TJ, Murray SS (2009) BDNF exerts contrasting effects on peripheral myelination of NGF-dependent and BDNF-dependent DRG neurons. J Neurosci 29: 4016-4022.
42. Xie Y, Yeo TT, Zhang C, Yang T, Tisi MA, Massa SM, Longo FM (2001) The leukocyte common antigen-related protein tyrosine phosphatase receptor regulates regenerative neurite outgrowth in vivo. J Neurosci 21: 5130-5138.
43. Xu P, Rosen KM, Hedstrom K, Rey O, Guha S, Hart C, Corfas G (2013) Nerve injury induces glial cell line-derived neurotrophic factor (GDNF) expression in Schwann cells through purinergic signaling and the PKC-PKD pathway. Glia 61: 1029-1040.
44. Yang MZ, Peng LJ, Hu WK (2013) Methylcobalamin induces differentiation of rat bone mesenchymal stem cells into neuron-like cells in vitro. Zhongguo Zuzhi Gongcheng Yanjiu 17: 5741-5748.
45. Yogeeswari P, Ragavendran JV, Sriram D (2007) Neuropathic pain: strategies in drug discovery and treatment. Expert Opin Drug Discov 2: 169-184.
46. Zhang H, Wu F, Kong X, Yang J, Chen H, Deng L, Cheng Y, Ye L, Zhu S, Zhang X, Wang Z, Shi H, Fu X, Li X, Xu H, Lin L, Xiao J (2014) Nerve growth factor improves functional recovery by inhibiting endoplasmic reticulum stress-induced neuronal apoptosis in rats with spinal cord injury. J Transl Med 12: 130.
47. Zhou S, Chen X, Gu X, Ding F (2009) Achyranthes bidentata Blume extract protects cultured hippocampal neurons against glutamate-induced neurotoxicity. J Ethnopharmacol 122: 547-554.
48. Ziv-Polat O, Shahar A, Levy I, Skaat H, Neuman S, Fregnan F, Geuna S, Grothe C, Haastert-Talini K, Margel S (2014) The role of neurotrophic factors conjugated to iron oxide nanoparticles in peripheral nerve regeneration: in vitro studies. Biomed Res Int 2014: 267808.