메뉴 건너뛰기




Volumn 34, Issue 12, 2014, Pages 931-937

Pharmacogenetics and the immunogenicity of protein therapeutics

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT BLOOD CLOTTING FACTOR 8;

EID: 84918504398     PISSN: 10799907     EISSN: 15577465     Source Type: Journal    
DOI: 10.1089/jir.2012.0136     Document Type: Review
Times cited : (10)

References (40)
  • 1
    • 80055114308 scopus 로고    scopus 로고
    • Can B-domain deletion alter the immunogenicity of recombinant factor VIII? A meta-analysis of prospective clinical studies
    • Aledort LM, Navickis RJ, Wilkes MM. 2011. Can B-domain deletion alter the immunogenicity of recombinant factor VIII? A meta-analysis of prospective clinical studies. J Thromb Haemost 9:2180-2192.
    • (2011) J Thromb Haemost , vol.9 , pp. 2180-2192
    • Aledort, L.M.1    Navickis, R.J.2    Wilkes, M.M.3
  • 4
    • 47649119586 scopus 로고    scopus 로고
    • Factor VIII genotype and inhibitor development in patients with haemophilia A: Highest risk in patients with splice site mutations
    • Boekhorst J, Lari GR, d'Oiron R, Costa JM, Novakova IR, Ala FA, Lavergne JM, VAN Heerde WL. 2008. Factor VIII genotype and inhibitor development in patients with haemophilia A: highest risk in patients with splice site mutations. Haemophilia 14:729-735.
    • (2008) Haemophilia , vol.14 , pp. 729-735
    • Boekhorst, J.1    Lari, G.R.2    D'Oiron, R.3    Costa, J.M.4    Novakova, I.R.5    Ala, F.A.6    Lavergne, J.M.7    Van Heerde, W.L.8
  • 5
    • 34548317168 scopus 로고    scopus 로고
    • Effect of recombinant factor VIIa variant (NN1731) on platelet function, clot structure and force onset time in whole blood from healthy volunteers and haemophilia patients
    • Brophy DF, Martin EJ, Nolte ME, Kuhn JG, Carr ME, Jr. 2007. Effect of recombinant factor VIIa variant (NN1731) on platelet function, clot structure and force onset time in whole blood from healthy volunteers and haemophilia patients. Haemophilia 13:533-541.
    • (2007) Haemophilia , vol.13 , pp. 533-541
    • Brophy, D.F.1    Martin, E.J.2    Nolte, M.E.3    Kuhn, J.G.4    Carr, M.E.5
  • 6
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogenomics: Translating functional genomics into rational therapeutics
    • Evans WE, Relling MV. 1999. Pharmacogenomics: translating functional genomics into rational therapeutics. Science 286:487-491.
    • (1999) Science , vol.286 , pp. 487-491
    • Evans, W.E.1    Relling, M.V.2
  • 11
    • 80055116249 scopus 로고    scopus 로고
    • Concentrate-related inhibitor risk: Is a difference always real?
    • Iorio A, Marcucci M, Makris M. 2011. Concentrate-related inhibitor risk: is a difference always real? J Thromb Haemost 9:2176-2179.
    • (2011) J Thromb Haemost , vol.9 , pp. 2176-2179
    • Iorio, A.1    Marcucci, M.2    Makris, M.3
  • 13
    • 49749154208 scopus 로고
    • Familial incidence of low pseudocholinesterase level
    • Kalow W. 1956. Familial incidence of low pseudocholinesterase level. Lancet 271:576-577.
    • (1956) Lancet , vol.271 , pp. 576-577
    • Kalow, W.1
  • 14
    • 33745961962 scopus 로고    scopus 로고
    • Protein therapeutics: New applications for pharmacogenetics
    • Krejsa C, Rogge M, Sadee W. 2006. Protein therapeutics: new applications for pharmacogenetics. Nat Rev Drug Discov 5:507-521.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 507-521
    • Krejsa, C.1    Rogge, M.2    Sadee, W.3
  • 15
    • 0026505030 scopus 로고
    • Irreversible association of peptides with class II MHC molecules in living cells
    • Lanzavecchia A, Reid PA, Watts C. 1992. Irreversible association of peptides with class II MHC molecules in living cells. Nature 357:249-252.
    • (1992) Nature , vol.357 , pp. 249-252
    • Lanzavecchia, A.1    Reid, P.A.2    Watts, C.3
  • 16
    • 77955925339 scopus 로고    scopus 로고
    • Improvements in factor concentrates
    • Lillicrap D. 2010. Improvements in factor concentrates. Curr Opin Hematol 17:393-397.
    • (2010) Curr Opin Hematol , vol.17 , pp. 393-397
    • Lillicrap, D.1
  • 17
    • 0035822038 scopus 로고    scopus 로고
    • Medical progress - The hemophilias - From royal genes to gene therapy
    • Mannucci PM, Tuddenham EGD. 2001. Medical progress - The hemophilias - From royal genes to gene therapy. New Engl J Med 344:1773-1779.
    • (2001) New Engl J Med , vol.344 , pp. 1773-1779
    • Mannucci, P.M.1    Tuddenham, E.G.D.2
  • 19
  • 21
    • 60149106150 scopus 로고    scopus 로고
    • Quality by design for biopharmaceuticals
    • Rathore AS, Winkle H. 2009. Quality by design for biopharmaceuticals. Nat Biotechnol 27:26-34.
    • (2009) Nat Biotechnol , vol.27 , pp. 26-34
    • Rathore, A.S.1    Winkle, H.2
  • 22
    • 10944231251 scopus 로고    scopus 로고
    • Risk-based approach to immunogenicity concerns of therapeutic protein products, part 2-Considering host specific and product specific factors impacting immunogenicity
    • Rosenberg AS. 2004. Risk-based approach to immunogenicity concerns of therapeutic protein products, part 2-Considering host specific and product specific factors impacting immunogenicity. BioPharm Int 17:34-42.
    • (2004) BioPharm Int , vol.17 , pp. 34-42
    • Rosenberg, A.S.1
  • 23
    • 16844367771 scopus 로고    scopus 로고
    • A risk-based approach to immunogenicity concerns fo therapeutic protein products
    • Rosenberg AS. 2005. A risk-based approach to immunogenicity concerns fo therapeutic protein products. BioPharm Int 18:32-36.
    • (2005) BioPharm Int , vol.18 , pp. 32-36
    • Rosenberg, A.S.1
  • 24
    • 9644287732 scopus 로고    scopus 로고
    • A risk-based approach to immunogenicity concerns of therapeutic protein products Part 1 Considering consequences of the immune response to a protein
    • Rosenberg AS, Worobec A. 2004. A risk-based approach to immunogenicity concerns of therapeutic protein products Part 1 Considering consequences of the immune response to a protein. BioPharm Int 17:22-26.
    • (2004) BioPharm Int , vol.17 , pp. 22-26
    • Rosenberg, A.S.1    Worobec, A.2
  • 26
    • 0029115540 scopus 로고
    • Inhibitors to factor VIII in a family with mild hemophilia: Molecular characterization and response to factor VIII and desmopressin
    • Santagostino E, Gringeri A, Tagliavacca L, Mannucci PM. 1995. Inhibitors to factor VIII in a family with mild hemophilia: molecular characterization and response to factor VIII and desmopressin. Thromb Haemost 74:619-621.
    • (1995) Thromb Haemost , vol.74 , pp. 619-621
    • Santagostino, E.1    Gringeri, A.2    Tagliavacca, L.3    Mannucci, P.M.4
  • 27
    • 84865790103 scopus 로고    scopus 로고
    • Observations regarding the immunogenicity of BDD-rFVIII derived from a mechanistic personalized medicine perspective
    • Sauna ZE, Ameri A, Kim B, Yanover C, Viel KR, Rajalingam R, Cole SA, Howard TE. 2012a. Observations regarding the immunogenicity of BDD-rFVIII derived from a mechanistic personalized medicine perspective. J Thromb Haemost 10:1961-1965.
    • (2012) J Thromb Haemost , vol.10 , pp. 1961-1965
    • Sauna, Z.E.1    Ameri, A.2    Kim, B.3    Yanover, C.4    Viel, K.R.5    Rajalingam, R.6    Cole, S.A.7    Howard, T.E.8
  • 30
    • 34249684926 scopus 로고    scopus 로고
    • A risk-based bioanalytical strategy for the assessment of antibody immune responses against biological drugs
    • Shankar G, Pendley C, Stein KE. 2007. A risk-based bioanalytical strategy for the assessment of antibody immune responses against biological drugs. Nat Biotechnol 25:555-561.
    • (2007) Nat Biotechnol , vol.25 , pp. 555-561
    • Shankar, G.1    Pendley, C.2    Stein, K.E.3
  • 33
    • 79952674000 scopus 로고    scopus 로고
    • Interactome networks and human disease
    • Vidal M, Cusick ME, Barabasi AL. 2011. Interactome networks and human disease. Cell 144:986-998.
    • (2011) Cell , vol.144 , pp. 986-998
    • Vidal, M.1    Cusick, M.E.2    Barabasi, A.L.3
  • 36
    • 77956690413 scopus 로고    scopus 로고
    • Biopharmaceutical benchmarks 2010
    • Walsh G. 2010. Biopharmaceutical benchmarks 2010. Nat Biotechnol 28:917-924.
    • (2010) Nat Biotechnol , vol.28 , pp. 917-924
    • Walsh, G.1
  • 38
    • 42949139524 scopus 로고    scopus 로고
    • A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach
    • Wang P, Sidney J, Dow C, Mothe B, Sette A, Peters B. 2008b. A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach. PLoS Comput Biol 4:e1000048.
    • (2008) PLoS Comput Biol , vol.4 , pp. e1000048
    • Wang, P.1    Sidney, J.2    Dow, C.3    Mothe, B.4    Sette, A.5    Peters, B.6
  • 40
    • 70349310353 scopus 로고    scopus 로고
    • Factor VIII Inhibitors: Risk factors and methods for prevention and immune modulation
    • Zhang AH, Skupsky J, Scott DW. 2009. Factor VIII Inhibitors: risk factors and methods for prevention and immune modulation. Clin Rev Allergy Immunol 37:114-124.
    • (2009) Clin Rev Allergy Immunol , vol.37 , pp. 114-124
    • Zhang, A.H.1    Skupsky, J.2    Scott, D.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.