-
1
-
-
0025812554
-
Bloom AL Progress in the clinical management of haemophilia
-
Bloom AL Progress in the clinical management of haemophilia. Thromb Haemost 1991; 66:166-177.
-
(1991)
Thromb Haemost
, vol.66
, pp. 166-177
-
-
-
2
-
-
34547436844
-
Coagulation factor concentrates: Past, present, and future
-
Key NS, Negrier C. Coagulation factor concentrates: past, present, and future. Lancet 2007; 370:439-448.
-
(2007)
Lancet
, vol.370
, pp. 439-448
-
-
Key, N.S.1
Negrier, C.2
-
3
-
-
0035822038
-
The hemophilias: From royal genes to gene therapy
-
Mannucci PM, Tuddenham EG. The hemophilias: from royal genes to gene therapy. N Engl J Med 2001; 344:1773-1779.
-
(2001)
N Engl J Med
, vol.344
, pp. 1773-1779
-
-
Mannucci, P.M.1
Tuddenham, E.G.2
-
5
-
-
0026635406
-
Twenty-five years' experience of prophylactic treatment in severe haemophilia A and B
-
Nilsson IM, Berntorp E, Lofqvist T, Pettersson H. Twenty-five years' experience of prophylactic treatment in severe haemophilia A and B. J Intern Med 1992; 232:25-32.
-
(1992)
J Intern Med
, vol.232
, pp. 25-32
-
-
Nilsson, I.M.1
Berntorp, E.2
Lofqvist, T.3
Pettersson, H.4
-
6
-
-
34547757915
-
Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia
-
Manco-Johnson MJ, Abshire TC, Shapiro AD, et al. Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia. N Engl J Med 2007; 357:535-544.
-
(2007)
N Engl J Med
, vol.357
, pp. 535-544
-
-
Manco-Johnson, M.J.1
Abshire, T.C.2
Shapiro, A.D.3
-
8
-
-
22144490270
-
Can long-term prophylaxis for severe haemophilia be stopped in adulthood? Results from Denmark and the Netherlands
-
van DK, Fischer K, van der Bom JG, et al. Can long-term prophylaxis for severe haemophilia be stopped in adulthood? Results from Denmark and the Netherlands. Br J Haematol 2005; 130:107-112.
-
(2005)
Br J Haematol
, vol.130
, pp. 107-112
-
-
Van Dk Fischer, K.1
Van Der Bom, J.G.2
-
9
-
-
77950211350
-
New early prophylaxis regimen that avoids immunological danger signals can reduce FVIII inhibitor development
-
Kurnik K, Bidlingmaier C, Engl W, et al. New early prophylaxis regimen that avoids immunological danger signals can reduce FVIII inhibitor development. Haemophilia 2010; 16:256-262.
-
(2010)
Haemophilia
, vol.16
, pp. 256-262
-
-
Kurnik, K.1
Bidlingmaier, C.2
Engl, W.3
-
10
-
-
33646759553
-
Tailored prophylaxis in severe hemophilia A: Interim results from the first 5 years of the Canadian Hemophilia Primary Prophylaxis Study
-
Feldman BM, Pai M, Rivard GE, et al. Tailored prophylaxis in severe hemophilia A: interim results from the first 5 years of the Canadian Hemophilia Primary Prophylaxis Study. J Thromb Haemost 2006; 4:1228-1236.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 1228-1236
-
-
Feldman, B.M.1
Pai, M.2
Rivard, G.E.3
-
11
-
-
0034651022
-
Reduction of the antigenicity of factor VIII toward complex inhibitory antibody plasmas using multiply-substituted hybrid human/porcine factor VIII molecules
-
Barrow RT, Healey JF, Gailani D, et al. Reduction of the antigenicity of factor VIII toward complex inhibitory antibody plasmas using multiply-substituted hybrid human/porcine factor VIII molecules. Blood 2000; 95:564-568.
-
(2000)
Blood
, vol.95
, pp. 564-568
-
-
Barrow, R.T.1
Healey, J.F.2
Gailani, D.3
-
12
-
-
15244354145
-
Factor IX variants improve gene therapy efficacy for hemophilia B
-
Schuettrumpf J, Herzog RW, Schlachterman A, et al. Factor IX variants improve gene therapy efficacy for hemophilia B. Blood 2005; 105:2316-2323.
-
(2005)
Blood
, vol.105
, pp. 2316-2323
-
-
Schuettrumpf, J.1
Herzog, R.W.2
Schlachterman, A.3
-
13
-
-
33845923722
-
Expression of human coagulation factor VIII in a human hybrid cell line, HKB11
-
Mei B, Chen Y, Chen J, et al. Expression of human coagulation factor VIII in a human hybrid cell line, HKB11. Mol Biotechnol 2006; 34:165-178.
-
(2006)
Mol Biotechnol
, vol.34
, pp. 165-178
-
-
Mei, B.1
Chen, Y.2
Chen, J.3
-
14
-
-
0031424112
-
Biosynthesis, assembly and secretion of coagulation factor VIII
-
Kaufman RJ, Pipe SW, Tagliavacca L, et al. Biosynthesis, assembly and secretion of coagulation factor VIII. Blood Coagul Fibrinolysis 1997; 8 (Suppl 2):S3-S14.
-
(1997)
Blood Coagul Fibrinolysis
, vol.8
, Issue.SUPPL. 2
-
-
Kaufman, R.J.1
Pipe, S.W.2
Tagliavacca, L.3
-
15
-
-
57449092891
-
Antioxidants reduce endoplasmic reticulum stress and improve protein secretion
-
Malhotra JD, Miao H, Zhang K, et al. Antioxidants reduce endoplasmic reticulum stress and improve protein secretion. Proc Natl Acad Sci USA 2008; 105:18525-18530.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 18525-18530
-
-
Malhotra, J.D.1
Miao, H.2
Zhang, K.3
-
16
-
-
69949106861
-
Enhancement of haemostatic efficacy of plasma-derived FVIII by formulation with PEGylated liposomes
-
Dayan I, Robinson M, Baru M. Enhancement of haemostatic efficacy of plasma-derived FVIII by formulation with PEGylated liposomes. Haemophilia 2009; 15:1006-1013.
-
(2009)
Haemophilia
, vol.15
, pp. 1006-1013
-
-
Dayan, I.1
Robinson, M.2
Baru, M.3
-
17
-
-
76149134362
-
Enhancement of the efficacy of therapeutic proteins by formulation with PEGylated liposomes; A case of FVIII, FVIIa and G-CSF
-
Yatuv R, Robinson M, Dayan I, Baru M. Enhancement of the efficacy of therapeutic proteins by formulation with PEGylated liposomes; a case of FVIII, FVIIa and G-CSF. Expert Opin Drug Deliv 2010; 7:187-201.
-
(2010)
Expert Opin Drug Deliv
, vol.7
, pp. 187-201
-
-
Yatuv, R.1
Robinson, M.2
Dayan, I.3
Baru, M.4
-
18
-
-
38349083504
-
Safety and pharmacokinetics of a recombinant factor VIII with pegylated liposomes in severe hemophilia A
-
Powell JS, Nugent DJ, Harrison JA, et al. Safety and pharmacokinetics of a recombinant factor VIII with pegylated liposomes in severe hemophilia A. J Thromb Haemost 2008; 6:277-283.
-
(2008)
J Thromb Haemost
, vol.6
, pp. 277-283
-
-
Powell, J.S.1
Nugent, D.J.2
Harrison, J.A.3
-
19
-
-
33845241302
-
Prolonged bleeding-free period following prophylactic infusion of recombinant factor VIII reconstituted with pegylated liposomes
-
Spira J, Plyushch OP, Andreeva TA, Andreev Y. Prolonged bleeding-free period following prophylactic infusion of recombinant factor VIII reconstituted with pegylated liposomes. Blood 2006; 108:3668-3673.
-
(2006)
Blood
, vol.108
, pp. 3668-3673
-
-
Spira, J.1
Plyushch, O.P.2
Andreeva, T.A.3
Andreev, Y.4
-
20
-
-
70350500718
-
Enhanced efficacy of recombinant FVIII in noncovalent complex with PEGylated liposome in hemophilia A mice
-
Pan J, Liu T, Kim JY, et al. Enhanced efficacy of recombinant FVIII in noncovalent complex with PEGylated liposome in hemophilia A mice. Blood 2009; 114:2802-2811.
-
(2009)
Blood
, vol.114
, pp. 2802-2811
-
-
Pan, J.1
Liu, T.2
Kim, J.Y.3
-
21
-
-
0036083609
-
Pegylation: Engineering improved pharmaceuticals for enhanced therapy
-
MolineuxG. Pegylation: engineering improved pharmaceuticals for enhanced therapy. Cancer Treat Rev 2002; 28 (Suppl A):13-16.
-
(2002)
Cancer Treat Rev
, vol.28
, Issue.SUPPL. A
, pp. 13-16
-
-
Molineux, G.1
-
22
-
-
33745107170
-
Strategies to improve plasma half life time of peptide and protein drugs
-
Werle M, Bernkop-Schnurch A. Strategies to improve plasma half life time of peptide and protein drugs. Amino Acids 2006; 30:351-367.
-
(2006)
Amino Acids
, vol.30
, pp. 351-367
-
-
Werle, M.1
Bernkop-Schnurch, A.2
-
23
-
-
0036750664
-
Pegylated interferons for the treatment of chronic hepatitis C infection
-
Luxon BA, Grace M, Brassard D, Bordens R. Pegylated interferons for the treatment of chronic hepatitis C infection. Clin Ther 2002; 24:1363-1383.
-
(2002)
Clin Ther
, vol.24
, pp. 1363-1383
-
-
Luxon, B.A.1
Grace, M.2
Brassard, D.3
Bordens, R.4
-
24
-
-
77955492929
-
Rational design of a fully active long-acting PEGylated factor VIII for hemophilia A treatment
-
[Epub ahead of print]
-
Mei B, Pan C, Jiang H, et al. Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment. Blood 2010 [Epub ahead of print].
-
(2010)
Blood
-
-
Mei, B.1
Pan, C.2
Jiang, H.3
-
25
-
-
34250767667
-
Clearance mechanisms of von Willebrand factor and factor VIII
-
Lenting PJ, Van Schooten CJ, Denis CV. Clearance mechanisms of von Willebrand factor and factor VIII. J Thromb Haemost 2007; 5:1353-1360.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 1353-1360
-
-
Lenting, P.J.1
Van Schooten, C.J.2
Denis, C.V.3
-
26
-
-
0032402122
-
The life cycle of coagulation factor VIII in view of its structure and function
-
Lenting PJ, Van MourikJA, Mertens K. The life cycle of coagulation factor VIII in view of its structure and function. Blood 1998; 92:3983-3996.
-
(1998)
Blood
, vol.92
, pp. 3983-3996
-
-
Lenting, P.J.1
Van Mourik, J.A.2
Mertens, K.3
-
27
-
-
28244484911
-
The promise and challenges of bioengineered recombinant clotting factors
-
Pipe SW. The promise and challenges of bioengineered recombinant clotting factors. J Thromb Haemost 2005; 3:1692-1701.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 1692-1701
-
-
Pipe, S.W.1
-
28
-
-
33646147385
-
Strategies towards a longer acting factor VIII
-
Saenko EL, Pipe SW. Strategies towards a longer acting factor VIII. Haemophilia 2006; 12 (Suppl 3):42-51.
-
(2006)
Haemophilia
, vol.12
, Issue.SUPPL. 3
, pp. 42-51
-
-
Saenko, E.L.1
Pipe, S.W.2
-
29
-
-
34548229364
-
FcRn: The neonatal Fc receptor comes of age
-
Roopenian DC, Akilesh S. FcRn: the neonatal Fc receptor comes of age. Nat Rev Immunol 2007; 7:715-725.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 715-725
-
-
Roopenian, D.C.1
Akilesh, S.2
-
30
-
-
77950391547
-
Prolonged activity of factor IX as a monomeric Fc fusion protein
-
Peters RT, Low SC, Kamphaus GD, et al. Prolonged activity of factor IX as a monomeric Fc fusion protein. Blood 2010; 115:2057-2064.
-
(2010)
Blood
, vol.115
, pp. 2057-2064
-
-
Peters, R.T.1
Low, S.C.2
Kamphaus, G.D.3
-
31
-
-
0030664471
-
Characterization of a genetically engineered inactiva-tion-resistant coagulation factor VIIIa
-
Pipe SW, Kaufman RJ. Characterization of a genetically engineered inactiva-tion-resistant coagulation factor VIIIa. Proc Natl Acad Sci USA 1997; 94:11851-11856.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 11851-11856
-
-
Pipe, S.W.1
Kaufman, R.J.2
-
32
-
-
33646765242
-
Intrinsic stability and functional properties of disulfide bond-stabilized coagulation factor VIIIa variants
-
Gale AJ, Radtke KP, Cunningham MA, et al. Intrinsic stability and functional properties of disulfide bond-stabilized coagulation factor VIIIa variants. J Thromb Haemost 2006; 4:1315-1322.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 1315-1322
-
-
Gale, A.J.1
Radtke, K.P.2
Cunningham, M.A.3
|